SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2gf9'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2C8A_C_NCAC1252_0
(MONO-ADP-RIBOSYLTRAN
SFERASE C3)		 2gf9 RAS-RELATED PROTEIN
RAB-3D
(Homo
sapiens) 		4 / 6 ARG A  41
SER A 165
PHE A  47
GLU A 168
 None
GDP  A 501 (-3.1A)
GDP  A 501 ( 4.4A)
None
 1.33A 2c8aC-2gf9A:
undetectable		 2c8aC-2gf9A:
21.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VDY_A_HCYA1384_1
(CORTICOSTEROID-BINDI
NG GLOBULIN)		 2gf9 RAS-RELATED PROTEIN
RAB-3D
(Homo
sapiens) 		5 / 12 VAL A 180
ARG A  66
ILE A  71
SER A  19
PHE A  23
 None
 1.42A 2vdyA-2gf9A:
undetectable		 2vdyA-2gf9A:
20.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R38_A_RBFA201_2
(BLUE-LIGHT-ACTIVATED
HISTIDINE KINASE 2)		 2gf9 RAS-RELATED PROTEIN
RAB-3D
(Homo
sapiens) 		5 / 8 ILE A  71
LEU A  39
VAL A 175
LEU A 179
PHE A  23
 None
 1.19A 4r38A-2gf9A:
undetectable		 4r38A-2gf9A:
20.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R38_B_RBFB201_2
(BLUE-LIGHT-ACTIVATED
HISTIDINE KINASE 2)		 2gf9 RAS-RELATED PROTEIN
RAB-3D
(Homo
sapiens) 		5 / 8 ILE A  71
LEU A  39
VAL A 175
LEU A 179
PHE A  23
 None
 1.21A 4r38B-2gf9A:
undetectable		 4r38B-2gf9A:
20.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R38_C_RBFC201_2
(BLUE-LIGHT-ACTIVATED
HISTIDINE KINASE 2)		 2gf9 RAS-RELATED PROTEIN
RAB-3D
(Homo
sapiens) 		5 / 9 ILE A  71
LEU A  39
VAL A 175
LEU A 179
PHE A  23
 None
 1.17A 4r38C-2gf9A:
undetectable		 4r38C-2gf9A:
20.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R38_D_RBFD201_2
(BLUE-LIGHT-ACTIVATED
HISTIDINE KINASE 2)		 2gf9 RAS-RELATED PROTEIN
RAB-3D
(Homo
sapiens) 		5 / 8 ILE A  71
LEU A  39
VAL A 175
LEU A 179
PHE A  23
 None
 1.18A 4r38D-2gf9A:
undetectable		 4r38D-2gf9A:
20.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R3A_B_RBFB402_1
(BLUE-LIGHT-ACTIVATED
HISTIDINE KINASE 2)		 2gf9 RAS-RELATED PROTEIN
RAB-3D
(Homo
sapiens) 		5 / 10 ILE A  71
LEU A  39
VAL A 175
LEU A 179
PHE A  23
 None
 1.24A 4r3aB-2gf9A:
undetectable		 4r3aB-2gf9A:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ECN_A_LEUA602_0
(JASMONIC ACID-AMIDO
SYNTHETASE JAR1)		 2gf9 RAS-RELATED PROTEIN
RAB-3D
(Homo
sapiens) 		4 / 7 ALA A  90
THR A  89
TYR A  92
GLU A  82
 None
 1.04A 5ecnA-2gf9A:
undetectable		 5ecnA-2gf9A:
16.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VCY_A_DB8A401_2
(MEMBRANE-ASSOCIATED
TYROSINE- AND
THREONINE-SPECIFIC
CDC2-INHIBITORY
KINASE)		 2gf9 RAS-RELATED PROTEIN
RAB-3D
(Homo
sapiens) 		4 / 4 VAL A 145
LEU A 153
ASN A 106
ASP A 103
 None
 1.16A 5vcyA-2gf9A:
undetectable		 5vcyA-2gf9A:
23.05