SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2ggj'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GMK_C_DVAC6_0
(GRAMICIDIN A)		 2ggj N-ACYLAMINO ACID
RACEMASE
(Deinococcus
radiodurans) 		3 / 3 ALA A 286
VAL A 265
TRP A 294
 None
 1.01A 1gmkC-2ggjA:
undetectable
1gmkD-2ggjA:
undetectable		 1gmkC-2ggjA:
4.64
1gmkD-2ggjA:
4.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DQY_A_CHDA1_0
(LIVER
CARBOXYLESTERASE 1)		 2ggj N-ACYLAMINO ACID
RACEMASE
(Deinococcus
radiodurans) 		4 / 5 TRP A 118
GLY A  50
LEU A 126
PRO A  90
 None
 1.24A 2dqyA-2ggjA:
1.6		 2dqyA-2ggjA:
21.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HZQ_A_STRA300_1
(APOLIPOPROTEIN D)		 2ggj N-ACYLAMINO ACID
RACEMASE
(Deinococcus
radiodurans) 		4 / 7 THR A 152
ALA A 196
TYR A 200
LEU A 211
 None
 1.08A 2hzqA-2ggjA:
undetectable		 2hzqA-2ggjA:
19.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EM0_B_CHDB151_0
(ILEAL BILE
ACID-BINDING PROTEIN)		 2ggj N-ACYLAMINO ACID
RACEMASE
(Deinococcus
radiodurans) 		5 / 12 TYR A 200
ILE A 238
ILE A 219
VAL A 194
PRO A 179
 None
 1.10A 3em0B-2ggjA:
undetectable		 3em0B-2ggjA:
14.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HCO_A_CHDA3_0
(FERROCHELATASE,
MITOCHONDRIAL)		 2ggj N-ACYLAMINO ACID
RACEMASE
(Deinococcus
radiodurans) 		4 / 4 LEU A 223
PRO A 222
LEU A 234
ARG A 236
 None
 1.44A 3hcoA-2ggjA:
3.1		 3hcoA-2ggjA:
20.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HRD_E_NIOE5660_1
(NICOTINATE
DEHYDROGENASE LARGE
MOLYBDOPTERIN
SUBUNIT
NICOTINATE
DEHYDROGENASE MEDIUM
MOLYBDOPTERIN
SUBUNIT)		 2ggj N-ACYLAMINO ACID
RACEMASE
(Deinococcus
radiodurans) 		3 / 3 GLU A 300
GLU A  53
TRP A 330
 None
 1.32A 3hrdA-2ggjA:
0.4
3hrdE-2ggjA:
undetectable
3hrdF-2ggjA:
undetectable		 3hrdA-2ggjA:
23.66
3hrdE-2ggjA:
23.66
3hrdF-2ggjA:
22.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V7P_A_BEZA430_0
(AMIDOHYDROLASE
FAMILY PROTEIN)		 2ggj N-ACYLAMINO ACID
RACEMASE
(Deinococcus
radiodurans) 		4 / 7 ILE A 303
GLY A 304
SER A 301
LEU A 339
 None
 0.80A 3v7pA-2ggjA:
5.6		 3v7pA-2ggjA:
22.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KLR_B_CHDB503_0
(FERROCHELATASE,
MITOCHONDRIAL)		 2ggj N-ACYLAMINO ACID
RACEMASE
(Deinococcus
radiodurans) 		4 / 8 ARG A 328
SER A 312
VAL A 141
GLY A 140
 None
 0.97A 4klrB-2ggjA:
2.6		 4klrB-2ggjA:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PCL_B_SAMB301_1
(O-METHYLTRANSFERASE
FAMILY PROTEIN)		 2ggj N-ACYLAMINO ACID
RACEMASE
(Deinococcus
radiodurans) 		4 / 4 SER A 324
GLU A 300
GLU A  57
ASP A 322
 None
 1.47A 4pclB-2ggjA:
0.7		 4pclB-2ggjA:
19.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Q15_A_HFGA803_1
(PROLINE--TRNA LIGASE)		 2ggj N-ACYLAMINO ACID
RACEMASE
(Deinococcus
radiodurans) 		3 / 3 GLU A  53
THR A 354
HIS A 307
 None
 0.86A 4q15A-2ggjA:
undetectable		 4q15A-2ggjA:
21.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CSW_A_P06A801_2
(SERINE/THREONINE-PRO
TEIN KINASE B-RAF)		 2ggj N-ACYLAMINO ACID
RACEMASE
(Deinococcus
radiodurans) 		3 / 3 PHE A  87
ILE A  10
ASP A 116
 None
 0.74A 5cswA-2ggjA:
undetectable		 5cswA-2ggjA:
21.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CSW_B_P06B801_2
(SERINE/THREONINE-PRO
TEIN KINASE B-RAF)		 2ggj N-ACYLAMINO ACID
RACEMASE
(Deinococcus
radiodurans) 		3 / 3 PHE A  87
ILE A  10
ASP A 116
 None
 0.72A 5cswB-2ggjA:
undetectable		 5cswB-2ggjA:
21.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5D4N_A_ACTA202_0
(NITROGEN REGULATORY
PROTEIN P-II)		 2ggj N-ACYLAMINO ACID
RACEMASE
(Deinococcus
radiodurans) 		4 / 4 VAL A  51
GLY A  50
ARG A 120
VAL A 356
 None
 1.20A 5d4nA-2ggjA:
0.1
5d4nB-2ggjA:
0.0		 5d4nA-2ggjA:
12.80
5d4nB-2ggjA:
12.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VOP_B_C2FB3001_1
(5-METHYLTETRAHYDROFO
LATE HOMOCYSTEINE
S-METHYLTRANSFERASE)		 2ggj N-ACYLAMINO ACID
RACEMASE
(Deinococcus
radiodurans) 		3 / 3 ASP A 245
ASN A 267
ASP A 322
 None
 0.90A 5vopB-2ggjA:
5.2		 5vopB-2ggjA:
25.82