SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2ggv'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1N49_D_RITD401_2
(PROTEASE)		 2ggv NON-STRUCTURAL
PROTEIN 3
(West
Nile
virus) 		4 / 6 ASP B  75
GLY B 148
ILE B 139
ILE B 123
 None
 0.93A 1n49D-2ggvB:
undetectable		 1n49D-2ggvB:
24.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1U18_B_HSMB402_1
(NITROPHORIN 1)		 2ggv NON-STRUCTURAL
PROTEIN 3
(West
Nile
virus) 		4 / 5 GLU B  74
THR B  48
LEU B  49
LEU B  77
 None
 1.22A 1u18B-2ggvB:
undetectable		 1u18B-2ggvB:
20.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QL8_B_BEZB143_0
(PUTATIVE REDOX
PROTEIN)		 2ggv NON-STRUCTURAL
PROTEIN 3
(West
Nile
virus) 		4 / 6 ARG B  24
THR B 134
ALA B  38
PRO B 131
 None
 1.37A 2ql8A-2ggvB:
undetectable
2ql8B-2ggvB:
undetectable		 2ql8A-2ggvB:
20.77
2ql8B-2ggvB:
20.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ARU_A_PNXA607_1
(CHITINASE A)		 2ggv NON-STRUCTURAL
PROTEIN 3
(West
Nile
virus) 		4 / 8 VAL B  99
GLY B 133
THR B 134
ALA B  38
 None
 0.74A 3aruA-2ggvB:
undetectable		 3aruA-2ggvB:
17.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SUF_D_SUED1201_1
(NS3 PROTEASE, NS4A
PROTEIN)		 2ggv NON-STRUCTURAL
PROTEIN 3
(West
Nile
virus) 		5 / 12 VAL B  72
ASP B  75
ILE B 162
ALA B 164
ALA B 125
 None
 1.02A 3sufD-2ggvB:
12.1		 3sufD-2ggvB:
22.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TKG_C_ROCC901_3
(PROTEASE)		 2ggv NON-STRUCTURAL
PROTEIN 3
(West
Nile
virus) 		3 / 3 ASP B  75
THR B 118
PRO B 119
 None
 0.64A 3tkgD-2ggvB:
undetectable		 3tkgD-2ggvB:
22.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P6X_G_HCYG900_2
(GLUCOCORTICOID
RECEPTOR)		 2ggv NON-STRUCTURAL
PROTEIN 3
(West
Nile
virus) 		3 / 3 LEU B 149
MET B  97
TYR B  23
 None
 0.90A 4p6xG-2ggvB:
undetectable		 4p6xG-2ggvB:
20.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4W5N_A_IPHA901_0
(PROTEIN ARGONAUTE-2)		 2ggv NON-STRUCTURAL
PROTEIN 3
(West
Nile
virus) 		3 / 3 VAL B  40
ALA B  38
PHE B  46
 None
 0.89A 4w5nA-2ggvB:
undetectable		 4w5nA-2ggvB:
14.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BRD_C_RFPC502_1
(RIFAMPIN
MONOOXYGENASE)		 2ggv NON-STRUCTURAL
PROTEIN 3
(West
Nile
virus) 		5 / 12 VAL B  22
VAL B  40
MET B  97
THR B 132
GLY B 133
 None
 1.10A 6brdC-2ggvB:
undetectable		 6brdC-2ggvB:
16.20