SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2gh0'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MJW_A_ACTA603_0
(CHOLINE OXIDASE)		 2gh0 GDNF FAMILY RECEPTOR
ALPHA-3
(Homo
sapiens) 		3 / 3 ARG A 287
HIS A 271
SER A 286
 None
 0.86A 4mjwA-2gh0A:
undetectable
4mjwB-2gh0A:
undetectable		 4mjwA-2gh0A:
15.50
4mjwB-2gh0A:
15.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MJW_B_ACTB603_0
(CHOLINE OXIDASE)		 2gh0 GDNF FAMILY RECEPTOR
ALPHA-3
(Homo
sapiens) 		3 / 3 SER A 286
ARG A 287
HIS A 271
 None
 0.93A 4mjwA-2gh0A:
undetectable
4mjwB-2gh0A:
undetectable		 4mjwA-2gh0A:
15.50
4mjwB-2gh0A:
15.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IEN_A_VDYA201_1
(CDL2.2)		 2gh0 GDNF FAMILY RECEPTOR
ALPHA-3
(Homo
sapiens) 		5 / 12 PHE A 204
LEU A 217
MET A 349
THR A 301
LEU A 341
 None
 1.29A 5ienA-2gh0A:
undetectable		 5ienA-2gh0A:
17.84