SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2gh8'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2C8A_C_NCAC1252_0
(MONO-ADP-RIBOSYLTRAN
SFERASE C3)		 2gh8 CAPSID PROTEIN
(Vesicular
exanthema
of
swine
virus) 		4 / 6 ARG A 588
SER A 584
PHE A 400
ARG A 398
 None
 1.40A 2c8aC-2gh8A:
undetectable		 2c8aC-2gh8A:
17.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NNK_A_ROCA401_2
(PROTEASE)		 2gh8 CAPSID PROTEIN
(Vesicular
exanthema
of
swine
virus) 		3 / 3 ARG A 385
VAL A 612
THR A 620
 None
 0.85A 2nnkA-2gh8A:
undetectable		 2nnkA-2gh8A:
11.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q6F_C_010C6_0
(INFECTIOUS
BRONCHITIS VIRUS
(IBV) MAIN PROTEASE
N-[(5-METHYLISOXAZOL
-3-YL)CARBONYL]ALANY
L-L-VALYL-N~1~-((1R,
2Z)-4-(BENZYLOXY)-4-
OXO-1-{[(3R)-2-OXOPY
RROLIDIN-3-YL]METHYL
}BUT-2-ENYL)-L-LEUCI
NAMIDE)		 2gh8 CAPSID PROTEIN
(Vesicular
exanthema
of
swine
virus) 		3 / 3 ASN A 225
LEU A 224
HIS A 308
 None
 0.77A 2q6fB-2gh8A:
undetectable		 2q6fB-2gh8A:
19.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XKW_B_P1BB1475_2
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 2gh8 CAPSID PROTEIN
(Vesicular
exanthema
of
swine
virus) 		4 / 6 LEU A 592
ARG A 398
ILE A 374
LEU A 634
 None
 0.76A 2xkwB-2gh8A:
undetectable		 2xkwB-2gh8A:
18.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JUS_B_ECNB602_1
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 2gh8 CAPSID PROTEIN
(Vesicular
exanthema
of
swine
virus) 		5 / 9 TYR A 552
THR A 496
PHE A 471
GLY A 570
THR A 501
 None
 1.40A 3jusB-2gh8A:
undetectable		 3jusB-2gh8A:
22.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K4V_B_ROCB201_2
(HIV-1 PROTEASE)		 2gh8 CAPSID PROTEIN
(Vesicular
exanthema
of
swine
virus) 		3 / 3 ARG A 385
VAL A 612
THR A 620
 None
 0.87A 3k4vA-2gh8A:
undetectable		 3k4vA-2gh8A:
11.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KM6_A_EAAA222_1
(GLUTATHIONE
S-TRANSFERASE P)		 2gh8 CAPSID PROTEIN
(Vesicular
exanthema
of
swine
virus) 		5 / 10 PHE A 659
GLY A 662
VAL A 702
ASN A 601
GLY A 672
 None
 1.28A 3km6A-2gh8A:
undetectable		 3km6A-2gh8A:
17.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KM6_A_EAAA222_1
(GLUTATHIONE
S-TRANSFERASE P)		 2gh8 CAPSID PROTEIN
(Vesicular
exanthema
of
swine
virus) 		6 / 10 VAL A 671
GLY A 662
VAL A 702
TRP A 658
GLN A 657
ILE A 374
 None
 1.32A 3km6A-2gh8A:
undetectable		 3km6A-2gh8A:
17.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KMO_A_EAAA214_1
(GLUTATHIONE
S-TRANSFERASE P)		 2gh8 CAPSID PROTEIN
(Vesicular
exanthema
of
swine
virus) 		5 / 9 PHE A 659
GLY A 662
VAL A 702
ASN A 601
GLY A 672
 None
 1.25A 3kmoA-2gh8A:
undetectable		 3kmoA-2gh8A:
17.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KMO_A_EAAA214_1
(GLUTATHIONE
S-TRANSFERASE P)		 2gh8 CAPSID PROTEIN
(Vesicular
exanthema
of
swine
virus) 		5 / 9 VAL A 671
GLY A 662
VAL A 702
TRP A 658
GLN A 657
 None
 1.34A 3kmoA-2gh8A:
undetectable		 3kmoA-2gh8A:
17.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NDU_D_ROCD100_3
(PROTEASE)		 2gh8 CAPSID PROTEIN
(Vesicular
exanthema
of
swine
virus) 		3 / 3 ARG A 385
VAL A 612
THR A 620
 None
 0.84A 3nduD-2gh8A:
undetectable		 3nduD-2gh8A:
11.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PEO_F_CU9F301_1
(SOLUBLE
ACETYLCHOLINE
RECEPTOR)		 2gh8 CAPSID PROTEIN
(Vesicular
exanthema
of
swine
virus) 		4 / 7 TRP A 415
TYR A 571
CYH A 622
TYR A 497
 None
 1.44A 3peoF-2gh8A:
0.0		 3peoF-2gh8A:
18.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PWR_A_ROCA401_2
(PROTEASE)		 2gh8 CAPSID PROTEIN
(Vesicular
exanthema
of
swine
virus) 		3 / 3 ARG A 385
VAL A 612
THR A 620
 None
 0.86A 3pwrA-2gh8A:
undetectable		 3pwrA-2gh8A:
11.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TL9_A_ROCA401_2
(PROTEASE)		 2gh8 CAPSID PROTEIN
(Vesicular
exanthema
of
swine
virus) 		3 / 3 ARG A 385
VAL A 612
THR A 620
 None
 0.86A 3tl9A-2gh8A:
undetectable		 3tl9A-2gh8A:
11.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TZF_B_08DB280_1
(7,8-DIHYDROPTEROATE
SYNTHASE)		 2gh8 CAPSID PROTEIN
(Vesicular
exanthema
of
swine
virus) 		4 / 8 PHE A 200
THR A 346
ARG A 347
PRO A 348
 None
 0.87A 3tzfB-2gh8A:
undetectable		 3tzfB-2gh8A:
19.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VNS_A_DVAA602_0
(NRPS ADENYLATION
PROTEIN CYTC1)		 2gh8 CAPSID PROTEIN
(Vesicular
exanthema
of
swine
virus) 		4 / 7 ASP A 409
PHE A 408
GLY A 667
THR A 411
 None
 1.01A 3vnsA-2gh8A:
undetectable		 3vnsA-2gh8A:
22.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M2X_A_TMQA202_2
(DIHYDROFOLATE
REDUCTASE)		 2gh8 CAPSID PROTEIN
(Vesicular
exanthema
of
swine
virus) 		3 / 3 TRP A 209
GLN A 657
THR A 339
 None
 0.99A 4m2xA-2gh8A:
undetectable		 4m2xA-2gh8A:
14.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4S0V_A_SUVA2001_1
(HUMAN OREXIN
RECEPTOR TYPE 2
FUSION PROTEIN TO P.
ABYSII GLYCOGEN
SYNTHASE)		 2gh8 CAPSID PROTEIN
(Vesicular
exanthema
of
swine
virus) 		5 / 12 THR A 458
VAL A 586
THR A 620
VAL A 612
TYR A 497
 None
 1.24A 4s0vA-2gh8A:
undetectable		 4s0vA-2gh8A:
20.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UXQ_A_0LIA1752_2
(FIBROBLAST GROWTH
FACTOR RECEPTOR 4)		 2gh8 CAPSID PROTEIN
(Vesicular
exanthema
of
swine
virus) 		4 / 7 MET A 279
ILE A 218
ALA A 699
ILE A 320
 None
 0.74A 4uxqA-2gh8A:
undetectable		 4uxqA-2gh8A:
19.78