SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2gh9'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FIQ_C_SALC1335_1
(XANTHINE OXIDASE)		 2gh9 MALTOSE/MALTODEXTRIN
-BINDING PROTEIN
(Thermus
thermophilus) 		5 / 8 LEU A 296
ARG A 305
PHE A 111
THR A  61
VAL A 271
 None
MLR  A2913 (-3.0A)
None
None
None
 1.31A 1fiqC-2gh9A:
undetectable		 1fiqC-2gh9A:
19.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FO4_A_SALA3005_1
(XANTHINE
DEHYDROGENASE)		 2gh9 MALTOSE/MALTODEXTRIN
-BINDING PROTEIN
(Thermus
thermophilus) 		5 / 9 LEU A 296
ARG A 305
PHE A 111
THR A  61
VAL A 271
 None
MLR  A2913 (-3.0A)
None
None
None
 1.32A 1fo4A-2gh9A:
0.0		 1fo4A-2gh9A:
15.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WU8_C_ADNC502_1
(HYPOTHETICAL PROTEIN
PH0463)		 2gh9 MALTOSE/MALTODEXTRIN
-BINDING PROTEIN
(Thermus
thermophilus) 		4 / 7 ASN A 159
TYR A 151
ASN A 152
VAL A 209
 None
 1.39A 1wu8A-2gh9A:
1.9
1wu8C-2gh9A:
1.8		 1wu8A-2gh9A:
24.87
1wu8C-2gh9A:
24.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2B9E_A_SAMA1201_0
(NOL1/NOP2/SUN DOMAIN
FAMILY, MEMBER 5
ISOFORM 2)		 2gh9 MALTOSE/MALTODEXTRIN
-BINDING PROTEIN
(Thermus
thermophilus) 		5 / 12 GLY A 167
ASN A 260
LYS A 164
ASP A 181
PHE A 172
 None
 1.32A 2b9eA-2gh9A:
undetectable		 2b9eA-2gh9A:
20.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2O4L_A_TPVA403_2
(PROTEASE)		 2gh9 MALTOSE/MALTODEXTRIN
-BINDING PROTEIN
(Thermus
thermophilus) 		5 / 12 GLY A  74
ALA A  73
GLY A  68
VAL A  67
ILE A  47
 None
 0.87A 2o4lB-2gh9A:
undetectable		 2o4lB-2gh9A:
18.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VE3_B_REAB1445_1
(PUTATIVE CYTOCHROME
P450 120)		 2gh9 MALTOSE/MALTODEXTRIN
-BINDING PROTEIN
(Thermus
thermophilus) 		5 / 12 ALA A  56
ALA A 283
VAL A 271
GLY A 270
GLN A 269
 None
None
None
None
MLR  A2913 (-4.3A)
 1.28A 2ve3B-2gh9A:
undetectable		 2ve3B-2gh9A:
21.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AX9_A_SALA1341_1
(XANTHINE
DEHYDROGENASE/OXIDAS
E)		 2gh9 MALTOSE/MALTODEXTRIN
-BINDING PROTEIN
(Thermus
thermophilus) 		5 / 8 LEU A 296
ARG A 305
PHE A 111
THR A  61
VAL A 271
 None
MLR  A2913 (-3.0A)
None
None
None
 1.33A 3ax9A-2gh9A:
undetectable		 3ax9A-2gh9A:
15.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KK6_B_CELB1701_2
(PROSTAGLANDIN G/H
SYNTHASE 1)		 2gh9 MALTOSE/MALTODEXTRIN
-BINDING PROTEIN
(Thermus
thermophilus) 		4 / 6 LEU A 180
ILE A 187
ALA A 333
LEU A 266
 None
 0.90A 3kk6B-2gh9A:
undetectable		 3kk6B-2gh9A:
20.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SPK_B_TPVB100_1
(HIV-1 PROTEASE)		 2gh9 MALTOSE/MALTODEXTRIN
-BINDING PROTEIN
(Thermus
thermophilus) 		5 / 9 ARG A 305
ASN A 300
VAL A 313
GLY A 324
ILE A 249
 MLR  A2913 (-3.0A)
None
None
None
None
 1.30A 3spkA-2gh9A:
undetectable		 3spkA-2gh9A:
15.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TEG_A_DAHA416_1
(PHENYLALANYL-TRNA
SYNTHETASE,
MITOCHONDRIAL)		 2gh9 MALTOSE/MALTODEXTRIN
-BINDING PROTEIN
(Thermus
thermophilus) 		5 / 12 PHE A 247
GLY A 304
GLY A 233
ALA A 236
GLY A 303
 None
 1.02A 3tegA-2gh9A:
undetectable		 3tegA-2gh9A:
21.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UNA_A_SALA1340_1
(XANTHINE
DEHYDROGENASE/OXIDAS
E)		 2gh9 MALTOSE/MALTODEXTRIN
-BINDING PROTEIN
(Thermus
thermophilus) 		5 / 9 LEU A 296
ARG A 305
PHE A 111
THR A  61
VAL A 271
 None
MLR  A2913 (-3.0A)
None
None
None
 1.32A 3unaA-2gh9A:
undetectable		 3unaA-2gh9A:
15.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UNA_B_SALB1340_1
(XANTHINE
DEHYDROGENASE/OXIDAS
E)		 2gh9 MALTOSE/MALTODEXTRIN
-BINDING PROTEIN
(Thermus
thermophilus) 		5 / 9 LEU A 296
ARG A 305
PHE A 111
THR A  61
VAL A 271
 None
MLR  A2913 (-3.0A)
None
None
None
 1.31A 3unaB-2gh9A:
0.0		 3unaB-2gh9A:
15.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UNC_A_SALA1338_1
(XANTHINE
DEHYDROGENASE/OXIDAS
E)		 2gh9 MALTOSE/MALTODEXTRIN
-BINDING PROTEIN
(Thermus
thermophilus) 		5 / 9 LEU A 296
ARG A 305
PHE A 111
THR A  61
VAL A 271
 None
MLR  A2913 (-3.0A)
None
None
None
 1.32A 3uncA-2gh9A:
0.0		 3uncA-2gh9A:
15.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UNC_B_SALB1338_1
(XANTHINE
DEHYDROGENASE/OXIDAS
E)		 2gh9 MALTOSE/MALTODEXTRIN
-BINDING PROTEIN
(Thermus
thermophilus) 		5 / 9 LEU A 296
ARG A 305
PHE A 111
THR A  61
VAL A 271
 None
MLR  A2913 (-3.0A)
None
None
None
 1.31A 3uncB-2gh9A:
0.0		 3uncB-2gh9A:
15.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ZOS_A_0LIA1004_1
(EPITHELIAL DISCOIDIN
DOMAIN-CONTAINING
RECEPTOR 1)		 2gh9 MALTOSE/MALTODEXTRIN
-BINDING PROTEIN
(Thermus
thermophilus) 		5 / 11 VAL A 254
ALA A 258
PHE A 329
VAL A 191
GLY A 161
 None
 1.06A 3zosA-2gh9A:
undetectable
3zosB-2gh9A:
undetectable		 3zosA-2gh9A:
24.33
3zosB-2gh9A:
24.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A6D_A_SAMA1350_0
(HYDROXYINDOLE
O-METHYLTRANSFERASE)		 2gh9 MALTOSE/MALTODEXTRIN
-BINDING PROTEIN
(Thermus
thermophilus) 		5 / 12 LEU A 185
GLY A 192
GLY A 189
ILE A 366
ALA A 168
 None
 1.15A 4a6dA-2gh9A:
undetectable		 4a6dA-2gh9A:
24.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A6E_A_SAMA1349_0
(HYDROXYINDOLE
O-METHYLTRANSFERASE)		 2gh9 MALTOSE/MALTODEXTRIN
-BINDING PROTEIN
(Thermus
thermophilus) 		5 / 12 LEU A 185
GLY A 192
GLY A 189
ILE A 366
ALA A 168
 None
 1.16A 4a6eA-2gh9A:
undetectable		 4a6eA-2gh9A:
24.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KYK_B_IMNB300_1
(LACTOYLGLUTATHIONE
LYASE)		 2gh9 MALTOSE/MALTODEXTRIN
-BINDING PROTEIN
(Thermus
thermophilus) 		5 / 12 PHE A 162
ALA A 165
PHE A 198
LEU A 202
LEU A 117
 None
 1.24A 4kykA-2gh9A:
undetectable
4kykB-2gh9A:
undetectable		 4kykA-2gh9A:
20.47
4kykB-2gh9A:
20.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OLB_A_TRPA901_0
(PROTEIN ARGONAUTE-2)		 2gh9 MALTOSE/MALTODEXTRIN
-BINDING PROTEIN
(Thermus
thermophilus) 		3 / 3 VAL A 273
ALA A 275
PHE A  46
 None
 0.86A 4olbA-2gh9A:
undetectable		 4olbA-2gh9A:
17.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OU1_A_BEZA302_0
(RETRO-ALDOLASE,
DESIGN RA114)		 2gh9 MALTOSE/MALTODEXTRIN
-BINDING PROTEIN
(Thermus
thermophilus) 		4 / 8 ILE A 199
LYS A 200
ILE A 352
ALA A 351
 None
 0.87A 4ou1A-2gh9A:
undetectable		 4ou1A-2gh9A:
21.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4W5N_A_IPHA901_0
(PROTEIN ARGONAUTE-2)		 2gh9 MALTOSE/MALTODEXTRIN
-BINDING PROTEIN
(Thermus
thermophilus) 		3 / 3 VAL A 273
ALA A 275
PHE A  46
 None
 0.91A 4w5nA-2gh9A:
undetectable		 4w5nA-2gh9A:
17.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XMF_A_HSMA202_1
(NITROPHORIN-7)		 2gh9 MALTOSE/MALTODEXTRIN
-BINDING PROTEIN
(Thermus
thermophilus) 		3 / 3 ASP A  90
LEU A 296
GLY A 293
 None
 0.55A 4xmfA-2gh9A:
undetectable		 4xmfA-2gh9A:
19.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z4I_A_IPHA903_0
(PROTEIN ARGONAUTE-2)		 2gh9 MALTOSE/MALTODEXTRIN
-BINDING PROTEIN
(Thermus
thermophilus) 		3 / 3 VAL A 273
ALA A 275
PHE A  46
 None
 0.83A 4z4iA-2gh9A:
undetectable		 4z4iA-2gh9A:
17.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JS1_A_IPHA902_0
(PROTEIN ARGONAUTE-2)		 2gh9 MALTOSE/MALTODEXTRIN
-BINDING PROTEIN
(Thermus
thermophilus) 		3 / 3 VAL A 273
ALA A 275
PHE A  46
 None
 0.87A 5js1A-2gh9A:
undetectable		 5js1A-2gh9A:
17.96