SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2ghi'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ONI_A_BEZA502_0
(14.5 KDA
TRANSLATIONAL
INHIBITOR PROTEIN)		 2ghi TRANSPORT PROTEIN
(Plasmodium
yoelii) 		4 / 6 PHE A 105
ASN A 106
ARG A 168
ILE A 103
 None
 1.04A 1oniA-2ghiA:
1.1
1oniB-2ghiA:
1.1		 1oniA-2ghiA:
19.92
1oniB-2ghiA:
19.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ONI_D_BEZD508_0
(14.5 KDA
TRANSLATIONAL
INHIBITOR PROTEIN)		 2ghi TRANSPORT PROTEIN
(Plasmodium
yoelii) 		4 / 6 PHE A 105
ASN A 106
ARG A 168
ILE A 103
 None
 1.07A 1oniD-2ghiA:
1.1
1oniF-2ghiA:
undetectable		 1oniD-2ghiA:
19.92
1oniF-2ghiA:
19.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SV9_A_DIFA701_1
(PHOSPHOLIPASE A2)		 2ghi TRANSPORT PROTEIN
(Plasmodium
yoelii) 		4 / 8 ALA A 165
ILE A 164
GLY A 159
PHE A 179
 None
 0.75A 1sv9A-2ghiA:
undetectable		 1sv9A-2ghiA:
19.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DCF_A_ACAA501_1
(6-AMINOHEXANOATE-DIM
ER HYDROLASE)		 2ghi TRANSPORT PROTEIN
(Plasmodium
yoelii) 		4 / 6 ALA A 220
TYR A 247
ILE A 209
ILE A 223
 None
 1.26A 2dcfA-2ghiA:
undetectable		 2dcfA-2ghiA:
19.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2H21_A_SAMA801_0
(RIBULOSE-1,5
BISPHOSPHATE
CARBOXYLASE/OXYGENAS
E)		 2ghi TRANSPORT PROTEIN
(Plasmodium
yoelii) 		5 / 10 GLU A  73
GLY A  74
ARG A  68
TYR A  70
PHE A  25
 None
 1.44A 2h21A-2ghiA:
undetectable		 2h21A-2ghiA:
21.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ELZ_A_CHDA150_0
(ILEAL BILE
ACID-BINDING PROTEIN)		 2ghi TRANSPORT PROTEIN
(Plasmodium
yoelii) 		5 / 12 GLN A  30
VAL A  23
LEU A  65
ILE A  39
THR A  61
 SO4  A2003 (-4.9A)
None
None
None
None
 1.40A 3elzA-2ghiA:
undetectable		 3elzA-2ghiA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ELZ_B_CHDB150_0
(ILEAL BILE
ACID-BINDING PROTEIN)		 2ghi TRANSPORT PROTEIN
(Plasmodium
yoelii) 		5 / 11 GLN A  30
VAL A  23
LEU A  65
ILE A  39
THR A  61
 SO4  A2003 (-4.9A)
None
None
None
None
 1.36A 3elzB-2ghiA:
0.0		 3elzB-2ghiA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_A_TFPA202_1
(PROTEIN S100-A4)		 2ghi TRANSPORT PROTEIN
(Plasmodium
yoelii) 		5 / 12 LEU A 156
SER A 157
ILE A 164
GLU A 160
LEU A 134
 None
 1.22A 3ko0A-2ghiA:
undetectable
3ko0B-2ghiA:
undetectable
3ko0C-2ghiA:
undetectable
3ko0D-2ghiA:
undetectable		 3ko0A-2ghiA:
17.14
3ko0B-2ghiA:
17.14
3ko0C-2ghiA:
17.14
3ko0D-2ghiA:
17.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_I_TFPI202_1
(PROTEIN S100-A4)		 2ghi TRANSPORT PROTEIN
(Plasmodium
yoelii) 		5 / 12 LEU A 156
SER A 157
ILE A 164
GLU A 160
LEU A 134
 None
 1.20A 3ko0G-2ghiA:
undetectable
3ko0H-2ghiA:
undetectable
3ko0I-2ghiA:
undetectable
3ko0J-2ghiA:
undetectable		 3ko0G-2ghiA:
17.14
3ko0H-2ghiA:
17.14
3ko0I-2ghiA:
17.14
3ko0J-2ghiA:
17.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_K_TFPK202_1
(PROTEIN S100-A4)		 2ghi TRANSPORT PROTEIN
(Plasmodium
yoelii) 		5 / 12 LEU A 156
SER A 157
ILE A 164
GLU A 160
LEU A 134
 None
 1.21A 3ko0K-2ghiA:
undetectable
3ko0L-2ghiA:
undetectable
3ko0S-2ghiA:
undetectable
3ko0T-2ghiA:
undetectable		 3ko0K-2ghiA:
17.14
3ko0L-2ghiA:
17.14
3ko0S-2ghiA:
17.14
3ko0T-2ghiA:
17.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_L_TFPL202_1
(PROTEIN S100-A4)		 2ghi TRANSPORT PROTEIN
(Plasmodium
yoelii) 		5 / 12 GLU A 160
LEU A 134
LEU A 156
SER A 157
ILE A 164
 None
 1.21A 3ko0K-2ghiA:
undetectable
3ko0L-2ghiA:
undetectable
3ko0M-2ghiA:
undetectable
3ko0N-2ghiA:
undetectable		 3ko0K-2ghiA:
17.14
3ko0L-2ghiA:
17.14
3ko0M-2ghiA:
17.14
3ko0N-2ghiA:
17.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_M_TFPM202_1
(PROTEIN S100-A4)		 2ghi TRANSPORT PROTEIN
(Plasmodium
yoelii) 		5 / 12 LEU A 156
SER A 157
ILE A 164
GLU A 160
LEU A 134
 None
 1.19A 3ko0M-2ghiA:
undetectable
3ko0N-2ghiA:
undetectable
3ko0O-2ghiA:
undetectable
3ko0P-2ghiA:
undetectable		 3ko0M-2ghiA:
17.14
3ko0N-2ghiA:
17.14
3ko0O-2ghiA:
17.14
3ko0P-2ghiA:
17.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_P_TFPP202_1
(PROTEIN S100-A4)		 2ghi TRANSPORT PROTEIN
(Plasmodium
yoelii) 		5 / 12 GLU A 160
LEU A 134
LEU A 156
SER A 157
ILE A 164
 None
 1.19A 3ko0M-2ghiA:
undetectable
3ko0N-2ghiA:
undetectable
3ko0O-2ghiA:
undetectable
3ko0P-2ghiA:
undetectable		 3ko0M-2ghiA:
17.14
3ko0N-2ghiA:
17.14
3ko0O-2ghiA:
17.14
3ko0P-2ghiA:
17.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P4W_C_DSFC320_1
(GLR4197 PROTEIN)		 2ghi TRANSPORT PROTEIN
(Plasmodium
yoelii) 		4 / 8 ILE A  91
ILE A  95
VAL A  83
ILE A  18
 None
 0.81A 3p4wC-2ghiA:
undetectable		 3p4wC-2ghiA:
22.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WDM_B_ADNB301_1
(4-PHOSPHOPANTOATE--B
ETA-ALANINE LIGASE)		 2ghi TRANSPORT PROTEIN
(Plasmodium
yoelii) 		5 / 10 GLY A 153
LEU A 141
LEU A 156
ASN A 151
ILE A 109
 None
 1.10A 3wdmB-2ghiA:
undetectable		 3wdmB-2ghiA:
25.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WDM_C_ADNC301_1
(4-PHOSPHOPANTOATE--B
ETA-ALANINE LIGASE)		 2ghi TRANSPORT PROTEIN
(Plasmodium
yoelii) 		5 / 9 GLY A 153
LEU A 141
LEU A 156
ASN A 151
ILE A 109
 None
 1.12A 3wdmC-2ghiA:
undetectable		 3wdmC-2ghiA:
25.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WDM_D_ADND301_1
(4-PHOSPHOPANTOATE--B
ETA-ALANINE LIGASE)		 2ghi TRANSPORT PROTEIN
(Plasmodium
yoelii) 		5 / 10 GLY A 153
LEU A 141
LEU A 156
ASN A 151
ILE A 109
 None
 1.12A 3wdmD-2ghiA:
undetectable		 3wdmD-2ghiA:
25.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NKX_A_STRA601_2
(STEROID
17-ALPHA-HYDROXYLASE
/17,20 LYASE)		 2ghi TRANSPORT PROTEIN
(Plasmodium
yoelii) 		4 / 6 LEU A 193
ASP A 136
GLU A 160
ALA A 167
 None
 0.97A 4nkxA-2ghiA:
undetectable		 4nkxA-2ghiA:
20.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CXV_A_0HKA501_2
(MUSCARINIC
ACETYLCHOLINE
RECEPTOR
M1,ENDOLYSIN,MUSCARI
NIC ACETYLCHOLINE
RECEPTOR M1)		 2ghi TRANSPORT PROTEIN
(Plasmodium
yoelii) 		3 / 3 THR A  47
THR A 206
PHE A  14
 None
 0.80A 5cxvA-2ghiA:
undetectable		 5cxvA-2ghiA:
18.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G08_A_Z80A1187_1
(FREQUENIN 2)		 2ghi TRANSPORT PROTEIN
(Plasmodium
yoelii) 		4 / 6 ILE A  18
PHE A  42
PHE A   5
THR A   8
 None
 1.34A 5g08A-2ghiA:
undetectable		 5g08A-2ghiA:
21.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KLA_A_ACTA1505_0
(MATERNAL PROTEIN
PUMILIO)		 2ghi TRANSPORT PROTEIN
(Plasmodium
yoelii) 		3 / 3 HIS A  10
LYS A  13
PHE A  14
 None
 1.15A 5klaA-2ghiA:
undetectable		 5klaA-2ghiA:
21.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MLM_A_STRA401_1
(-)		 2ghi TRANSPORT PROTEIN
(Plasmodium
yoelii) 		5 / 12 PHE A  20
ILE A  18
SER A  90
VAL A  83
ILE A  78
 None
 1.32A 5mlmA-2ghiA:
undetectable		 5mlmA-2ghiA:
21.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GSD_A_STRA401_0
(PROGESTERONE
5-BETA-REDUCTASE)		 2ghi TRANSPORT PROTEIN
(Plasmodium
yoelii) 		5 / 12 PHE A  20
ILE A  18
SER A  90
VAL A  83
ILE A  78
 None
 1.38A 6gsdA-2ghiA:
undetectable		 6gsdA-2ghiA:
13.08