SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2ghs'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1CMA_B_SAMB105_0
(PROTEIN (MET
REPRESSOR))		 2ghs AGR_C_1268P
(Agrobacterium
fabrum) 		5 / 11 GLU A  40
LEU A  38
GLU A 281
HIS A 294
GLY A 258
 EDO  A 317 (-3.9A)
None
None
None
None
 1.12A 1cmaA-2ghsA:
undetectable
1cmaB-2ghsA:
undetectable		 1cmaA-2ghsA:
14.84
1cmaB-2ghsA:
14.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1CMA_B_SAMB105_0
(PROTEIN (MET
REPRESSOR))		 2ghs AGR_C_1268P
(Agrobacterium
fabrum) 		5 / 11 GLU A 281
LEU A  37
HIS A 294
LEU A 283
GLY A 237
 None
 1.29A 1cmaA-2ghsA:
undetectable
1cmaB-2ghsA:
undetectable		 1cmaA-2ghsA:
14.84
1cmaB-2ghsA:
14.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1CMC_A_SAMA105_0
(MET REPRESSOR)		 2ghs AGR_C_1268P
(Agrobacterium
fabrum) 		5 / 10 GLY A 237
GLU A 281
LEU A  37
HIS A 294
LEU A 283
 None
 1.23A 1cmcA-2ghsA:
undetectable
1cmcB-2ghsA:
undetectable		 1cmcA-2ghsA:
14.84
1cmcB-2ghsA:
14.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1CMC_B_SAMB105_0
(MET REPRESSOR)		 2ghs AGR_C_1268P
(Agrobacterium
fabrum) 		5 / 10 GLU A 281
LEU A  37
HIS A 294
LEU A 283
GLY A 237
 None
 1.23A 1cmcA-2ghsA:
undetectable
1cmcB-2ghsA:
undetectable		 1cmcA-2ghsA:
14.84
1cmcB-2ghsA:
14.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MJ2_A_SAMA2200_0
(PROTEIN (METHIONINE
REPRESSOR))		 2ghs AGR_C_1268P
(Agrobacterium
fabrum) 		5 / 12 GLY A 237
GLU A 281
LEU A  37
HIS A 294
LEU A 283
 None
 1.21A 1mj2A-2ghsA:
undetectable
1mj2B-2ghsA:
undetectable		 1mj2A-2ghsA:
16.13
1mj2B-2ghsA:
16.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MJ2_A_SAMA2200_0
(PROTEIN (METHIONINE
REPRESSOR))		 2ghs AGR_C_1268P
(Agrobacterium
fabrum) 		5 / 12 HIS A 294
GLY A 258
GLU A  40
LEU A  38
GLU A 281
 None
None
EDO  A 317 (-3.9A)
None
None
 1.07A 1mj2A-2ghsA:
undetectable
1mj2B-2ghsA:
undetectable		 1mj2A-2ghsA:
16.13
1mj2B-2ghsA:
16.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MJ2_C_SAMC2199_0
(PROTEIN (METHIONINE
REPRESSOR))		 2ghs AGR_C_1268P
(Agrobacterium
fabrum) 		5 / 12 GLY A 237
GLU A 281
LEU A  37
HIS A 294
LEU A 283
 None
 1.25A 1mj2C-2ghsA:
undetectable
1mj2D-2ghsA:
undetectable		 1mj2C-2ghsA:
16.13
1mj2D-2ghsA:
16.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MJ2_C_SAMC2199_0
(PROTEIN (METHIONINE
REPRESSOR))		 2ghs AGR_C_1268P
(Agrobacterium
fabrum) 		5 / 12 HIS A 294
GLY A 258
GLU A  40
LEU A  38
GLU A 281
 None
None
EDO  A 317 (-3.9A)
None
None
 1.02A 1mj2C-2ghsA:
undetectable
1mj2D-2ghsA:
undetectable		 1mj2C-2ghsA:
16.13
1mj2D-2ghsA:
16.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MJL_B_SAMB400_0
(METHIONINE REPRESSOR
PROTEIN METJ)		 2ghs AGR_C_1268P
(Agrobacterium
fabrum) 		5 / 9 GLU A  40
LEU A  38
GLU A 281
HIS A 294
GLY A 258
 EDO  A 317 (-3.9A)
None
None
None
None
 1.19A 1mjlA-2ghsA:
undetectable
1mjlB-2ghsA:
undetectable		 1mjlA-2ghsA:
16.13
1mjlB-2ghsA:
16.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MJL_B_SAMB400_0
(METHIONINE REPRESSOR
PROTEIN METJ)		 2ghs AGR_C_1268P
(Agrobacterium
fabrum) 		5 / 9 GLU A 281
LEU A  37
HIS A 294
LEU A 283
GLY A 237
 None
 1.34A 1mjlA-2ghsA:
undetectable
1mjlB-2ghsA:
undetectable		 1mjlA-2ghsA:
16.13
1mjlB-2ghsA:
16.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MJO_C_SAMC200_0
(METHIONINE REPRESSOR)		 2ghs AGR_C_1268P
(Agrobacterium
fabrum) 		5 / 12 GLY A 237
GLU A 281
LEU A  37
HIS A 294
LEU A 283
 None
 1.22A 1mjoC-2ghsA:
undetectable
1mjoD-2ghsA:
undetectable		 1mjoC-2ghsA:
16.13
1mjoD-2ghsA:
16.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MJO_C_SAMC200_0
(METHIONINE REPRESSOR)		 2ghs AGR_C_1268P
(Agrobacterium
fabrum) 		5 / 12 HIS A 294
GLY A 258
GLU A  40
LEU A  38
GLU A 281
 None
None
EDO  A 317 (-3.9A)
None
None
 1.04A 1mjoC-2ghsA:
undetectable
1mjoD-2ghsA:
undetectable		 1mjoC-2ghsA:
16.13
1mjoD-2ghsA:
16.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MJQ_A_SAMA200_0
(METHIONINE REPRESSOR)		 2ghs AGR_C_1268P
(Agrobacterium
fabrum) 		5 / 11 GLU A  40
LEU A  38
GLU A 281
HIS A 294
GLY A 258
 EDO  A 317 (-3.9A)
None
None
None
None
 1.11A 1mjqA-2ghsA:
undetectable
1mjqB-2ghsA:
undetectable		 1mjqA-2ghsA:
16.13
1mjqB-2ghsA:
16.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MJQ_B_SAMB200_0
(METHIONINE REPRESSOR)		 2ghs AGR_C_1268P
(Agrobacterium
fabrum) 		5 / 11 GLU A 238
GLY A 239
GLU A  40
LEU A  38
GLU A 281
 None
None
EDO  A 317 (-3.9A)
None
None
 1.16A 1mjqA-2ghsA:
undetectable
1mjqB-2ghsA:
undetectable		 1mjqA-2ghsA:
16.13
1mjqB-2ghsA:
16.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MJQ_B_SAMB200_0
(METHIONINE REPRESSOR)		 2ghs AGR_C_1268P
(Agrobacterium
fabrum) 		5 / 11 GLY A 237
GLU A 281
LEU A  37
HIS A 294
LEU A 283
 None
 1.24A 1mjqA-2ghsA:
undetectable
1mjqB-2ghsA:
undetectable		 1mjqA-2ghsA:
16.13
1mjqB-2ghsA:
16.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MJQ_C_SAMC199_0
(METHIONINE REPRESSOR)		 2ghs AGR_C_1268P
(Agrobacterium
fabrum) 		5 / 10 GLU A 281
LEU A  37
HIS A 294
LEU A 283
GLY A 237
 None
 1.24A 1mjqC-2ghsA:
undetectable
1mjqD-2ghsA:
undetectable		 1mjqC-2ghsA:
16.13
1mjqD-2ghsA:
16.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MJQ_D_SAMD200_0
(METHIONINE REPRESSOR)		 2ghs AGR_C_1268P
(Agrobacterium
fabrum) 		5 / 12 HIS A 294
GLY A 258
GLU A  40
LEU A  38
GLU A 281
 None
None
EDO  A 317 (-3.9A)
None
None
 1.16A 1mjqC-2ghsA:
undetectable
1mjqD-2ghsA:
undetectable		 1mjqC-2ghsA:
16.13
1mjqD-2ghsA:
16.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MJQ_H_SAMH200_0
(METHIONINE REPRESSOR)		 2ghs AGR_C_1268P
(Agrobacterium
fabrum) 		5 / 10 GLY A 237
GLU A 281
LEU A  37
HIS A 294
LEU A 283
 None
 1.24A 1mjqG-2ghsA:
undetectable
1mjqH-2ghsA:
undetectable		 1mjqG-2ghsA:
16.13
1mjqH-2ghsA:
16.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MJQ_I_SAMI199_0
(METHIONINE REPRESSOR)		 2ghs AGR_C_1268P
(Agrobacterium
fabrum) 		5 / 11 GLU A  40
LEU A  38
GLU A 281
HIS A 294
GLY A 258
 EDO  A 317 (-3.9A)
None
None
None
None
 1.14A 1mjqI-2ghsA:
undetectable
1mjqJ-2ghsA:
undetectable		 1mjqI-2ghsA:
16.13
1mjqJ-2ghsA:
16.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MJQ_I_SAMI199_0
(METHIONINE REPRESSOR)		 2ghs AGR_C_1268P
(Agrobacterium
fabrum) 		5 / 11 GLU A 281
LEU A  37
HIS A 294
LEU A 283
GLY A 237
 None
 1.23A 1mjqI-2ghsA:
undetectable
1mjqJ-2ghsA:
undetectable		 1mjqI-2ghsA:
16.13
1mjqJ-2ghsA:
16.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MJQ_J_SAMJ200_0
(METHIONINE REPRESSOR)		 2ghs AGR_C_1268P
(Agrobacterium
fabrum) 		5 / 12 HIS A 294
GLY A 258
GLU A  40
LEU A  38
GLU A 281
 None
None
EDO  A 317 (-3.9A)
None
None
 1.15A 1mjqI-2ghsA:
undetectable
1mjqJ-2ghsA:
undetectable		 1mjqI-2ghsA:
16.13
1mjqJ-2ghsA:
16.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V55_W_CHDW4060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE I
CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART)		 2ghs AGR_C_1268P
(Agrobacterium
fabrum) 		5 / 8 ILE A 151
LEU A 162
PHE A 163
THR A 180
LEU A 196
 None
 1.21A 1v55N-2ghsA:
undetectable
1v55W-2ghsA:
undetectable		 1v55N-2ghsA:
21.64
1v55W-2ghsA:
11.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DU8_A_BEZA352_0
(D-AMINO-ACID OXIDASE)		 2ghs AGR_C_1268P
(Agrobacterium
fabrum) 		4 / 6 LEU A  99
TYR A 312
ILE A 137
GLY A 133
 None
 0.88A 2du8A-2ghsA:
undetectable		 2du8A-2ghsA:
23.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DU8_B_BEZB1352_0
(D-AMINO-ACID OXIDASE)		 2ghs AGR_C_1268P
(Agrobacterium
fabrum) 		4 / 6 LEU A  99
TYR A 312
ILE A 137
GLY A 133
 None
 0.91A 2du8B-2ghsA:
undetectable		 2du8B-2ghsA:
23.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIN_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 1)		 2ghs AGR_C_1268P
(Agrobacterium
fabrum) 		5 / 8 ILE A 151
LEU A 162
PHE A 163
THR A 180
LEU A 196
 None
 1.16A 2einA-2ghsA:
undetectable
2einJ-2ghsA:
undetectable		 2einA-2ghsA:
21.64
2einJ-2ghsA:
11.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASO_W_CHDW1059_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1)		 2ghs AGR_C_1268P
(Agrobacterium
fabrum) 		5 / 8 ILE A 151
LEU A 162
PHE A 163
THR A 180
LEU A 196
 None
 1.24A 3asoN-2ghsA:
undetectable
3asoW-2ghsA:
undetectable		 3asoN-2ghsA:
21.64
3asoW-2ghsA:
11.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LSL_D_PZID802_0
(GLUTAMATE RECEPTOR 2)		 2ghs AGR_C_1268P
(Agrobacterium
fabrum) 		3 / 3 SER A 223
ASP A 126
ASN A 125
 None
None
EDO  A 317 (-3.0A)
 0.73A 3lslA-2ghsA:
undetectable
3lslD-2ghsA:
undetectable		 3lslA-2ghsA:
21.86
3lslD-2ghsA:
21.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N62_B_ACTB860_0
(NITRIC OXIDE
SYNTHASE)		 2ghs AGR_C_1268P
(Agrobacterium
fabrum) 		3 / 3 GLY A 306
TRP A 232
VAL A 224
 None
 0.75A 3n62B-2ghsA:
undetectable		 3n62B-2ghsA:
21.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N65_B_ACTB860_0
(NITRIC OXIDE
SYNTHASE)		 2ghs AGR_C_1268P
(Agrobacterium
fabrum) 		3 / 3 GLY A 306
TRP A 232
VAL A 224
 None
 0.75A 3n65B-2ghsA:
undetectable		 3n65B-2ghsA:
22.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N66_B_ACTB860_0
(NITRIC OXIDE
SYNTHASE)		 2ghs AGR_C_1268P
(Agrobacterium
fabrum) 		3 / 3 GLY A 306
TRP A 232
VAL A 224
 None
 0.77A 3n66B-2ghsA:
undetectable		 3n66B-2ghsA:
22.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3R75_A_BEZA701_0
(ANTHRANILATE/PARA-AM
INOBENZOATE
SYNTHASES COMPONENT
I)		 2ghs AGR_C_1268P
(Agrobacterium
fabrum) 		5 / 12 ILE A 151
SER A 150
GLY A 149
THR A 139
GLU A 116
 None
 1.14A 3r75A-2ghsA:
undetectable		 3r75A-2ghsA:
20.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3R75_B_BEZB701_0
(ANTHRANILATE/PARA-AM
INOBENZOATE
SYNTHASES COMPONENT
I)		 2ghs AGR_C_1268P
(Agrobacterium
fabrum) 		5 / 12 ILE A 151
SER A 150
GLY A 149
THR A 139
GLU A 116
 None
 1.14A 3r75B-2ghsA:
undetectable		 3r75B-2ghsA:
20.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3R76_A_BEZA701_0
(ANTHRANILATE/PARA-AM
INOBENZOATE
SYNTHASES COMPONENT
I)		 2ghs AGR_C_1268P
(Agrobacterium
fabrum) 		5 / 11 ILE A 151
SER A 150
GLY A 149
THR A 139
GLU A 116
 None
 1.15A 3r76A-2ghsA:
undetectable		 3r76A-2ghsA:
20.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3R76_B_BEZB701_0
(ANTHRANILATE/PARA-AM
INOBENZOATE
SYNTHASES COMPONENT
I)		 2ghs AGR_C_1268P
(Agrobacterium
fabrum) 		5 / 11 ILE A 151
SER A 150
GLY A 149
THR A 139
GLU A 116
 None
 1.16A 3r76B-2ghsA:
undetectable		 3r76B-2ghsA:
20.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TEH_B_DAHB786_1
(PHENYLALANYL-TRNA
SYNTHETASE BETA
CHAIN)		 2ghs AGR_C_1268P
(Agrobacterium
fabrum) 		4 / 7 LEU A 275
GLY A 222
GLU A  40
ALA A 234
 None
None
EDO  A 317 (-3.9A)
None
 0.89A 3tehB-2ghsA:
undetectable		 3tehB-2ghsA:
18.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N48_B_SAMB601_1
(CAP-SPECIFIC MRNA
(NUCLEOSIDE-2'-O-)-M
ETHYLTRANSFERASE 1)		 2ghs AGR_C_1268P
(Agrobacterium
fabrum) 		4 / 5 ASN A 125
PRO A 169
ASP A 212
ASP A 221
 EDO  A 317 (-3.0A)
None
None
EDO  A 317 (-3.7A)
 1.13A 4n48B-2ghsA:
undetectable		 4n48B-2ghsA:
21.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X3U_B_SVRB102_1
(CHROMOBOX PROTEIN
HOMOLOG 7)		 2ghs AGR_C_1268P
(Agrobacterium
fabrum) 		3 / 3 LYS A  71
ARG A  29
VAL A  30
 None
 0.61A 4x3uA-2ghsA:
undetectable
4x3uB-2ghsA:
undetectable		 4x3uA-2ghsA:
12.00
4x3uB-2ghsA:
12.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YNM_A_SAMA2304_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
ASH1L)		 2ghs AGR_C_1268P
(Agrobacterium
fabrum) 		5 / 12 GLY A 219
TRP A 236
ASN A 233
TYR A 244
ILE A 211
 None
 1.41A 4ynmA-2ghsA:
undetectable		 4ynmA-2ghsA:
18.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YNM_B_SAMB2304_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
ASH1L)		 2ghs AGR_C_1268P
(Agrobacterium
fabrum) 		5 / 12 GLY A 219
TRP A 236
ASN A 233
TYR A 244
ILE A 211
 None
 1.49A 4ynmB-2ghsA:
undetectable		 4ynmB-2ghsA:
18.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YPE_A_SAMA2304_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
ASH1L)		 2ghs AGR_C_1268P
(Agrobacterium
fabrum) 		5 / 12 GLY A 219
TRP A 236
ASN A 233
TYR A 244
ILE A 211
 None
 1.42A 4ypeA-2ghsA:
undetectable		 4ypeA-2ghsA:
18.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IWU_A_ERYA404_1
(MACROLIDE
2'-PHOSPHOTRANSFERAS
E II)		 2ghs AGR_C_1268P
(Agrobacterium
fabrum) 		4 / 6 GLY A 121
ASP A 165
ILE A 151
TYR A 152
 None
 1.11A 5iwuA-2ghsA:
1.6		 5iwuA-2ghsA:
24.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TJZ_A_BEZA302_0
(4-HYDROXY-TETRAHYDRO
DIPICOLINATE
REDUCTASE)		 2ghs AGR_C_1268P
(Agrobacterium
fabrum) 		3 / 3 MET A  79
GLU A 281
ARG A 123
 None
None
EDO  A 317 (-3.1A)
 0.98A 5tjzA-2ghsA:
undetectable		 5tjzA-2ghsA:
23.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUO_B_ACTB804_0
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2ghs AGR_C_1268P
(Agrobacterium
fabrum) 		3 / 3 GLY A 306
TRP A 232
VAL A 224
 None
 0.76A 5vuoB-2ghsA:
undetectable		 5vuoB-2ghsA:
21.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCP_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 2ghs AGR_C_1268P
(Agrobacterium
fabrum) 		5 / 8 ILE A 151
LEU A 162
PHE A 163
THR A 180
LEU A 196
 None
 1.26A 5zcpN-2ghsA:
undetectable
5zcpW-2ghsA:
undetectable		 5zcpN-2ghsA:
21.64
5zcpW-2ghsA:
11.79