SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2giy'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)	View	Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1GMK_A_DVAA8_0 (GRAMICIDIN A)	2giy	GLYCOPROTEIN E (Human alphaherpesvirus 1)	3 / 4	VAL A 261 TRP A 370 TRP A 302	None	1.43A	1gmkA-2giyA: undetectable 1gmkB-2giyA: undetectable	1gmkA-2giyA: 6.88 1gmkB-2giyA: 6.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1SS4_A_ACTA411_0 (GLYOXALASE FAMILY PROTEIN)	2giy	GLYCOPROTEIN E (Human alphaherpesvirus 1)	4 / 5	TRP A 262 VAL A 244 THR A 228 ILE A 375	None	1.38A	1ss4A-2giyA: 0.0	1ss4A-2giyA: 19.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3R9S_A_BEZA264_0 (CARNITINYL-COA DEHYDRATASE)	2giy	GLYCOPROTEIN E (Human alphaherpesvirus 1)	4 / 6	ALA A 384 ILE A 276 LEU A 356 ALA A 231	None	0.66A	3r9sA-2giyA: undetectable	3r9sA-2giyA: 22.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3R9S_C_BEZC264_0 (CARNITINYL-COA DEHYDRATASE)	2giy	GLYCOPROTEIN E (Human alphaherpesvirus 1)	4 / 6	ALA A 384 ILE A 276 LEU A 356 ALA A 231	None	0.67A	3r9sC-2giyA: undetectable	3r9sC-2giyA: 22.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3R9T_A_BEZA264_0 (ECHA1_1)	2giy	GLYCOPROTEIN E (Human alphaherpesvirus 1)	4 / 8	ALA A 384 ILE A 276 LEU A 356 ALA A 231	None	0.69A	3r9tA-2giyA: undetectable	3r9tA-2giyA: 23.13

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1GMK_A_DVAA8_0","GRAMICIDIN A","2giy","GLYCOPROTEIN E","Human alphaherpesvirus 1",3,"VAL A 261;TRP A 370;TRP A 302","None","1.43A","1gmkA-2giyA:undetectable;1gmkB-2giyA:undetectable","1gmkA-2giyA:6.88;1gmkB-2giyA:6.88"],["1SS4_A_ACTA411_0","GLYOXALASE FAMILY PROTEIN","2giy","GLYCOPROTEIN E","Human alphaherpesvirus 1",4,"TRP A 262;VAL A 244;THR A 228;ILE A 375","None","1.38A","1ss4A-2giyA:0.0","1ss4A-2giyA:19.80"],["3R9S_A_BEZA264_0","CARNITINYL-COA DEHYDRATASE","2giy","GLYCOPROTEIN E","Human alphaherpesvirus 1",4,"ALA A 384;ILE A 276;LEU A 356;ALA A 231","None","0.66A","3r9sA-2giyA:undetectable","3r9sA-2giyA:22.39"],["3R9S_C_BEZC264_0","CARNITINYL-COA DEHYDRATASE","2giy","GLYCOPROTEIN E","Human alphaherpesvirus 1",4,"ALA A 384;ILE A 276;LEU A 356;ALA A 231","None","0.67A","3r9sC-2giyA:undetectable","3r9sC-2giyA:22.39"],["3R9T_A_BEZA264_0","ECHA1_1","2giy","GLYCOPROTEIN E","Human alphaherpesvirus 1",4,"ALA A 384;ILE A 276;LEU A 356;ALA A 231","None","0.69A","3r9tA-2giyA:undetectable","3r9tA-2giyA:23.13"]]