SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2gj2'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QX6_A_ML1A233_1
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 2gj2 WSV230
(White
spot
syndrome
virus) 		4 / 6 PHE A  27
PHE A  53
GLY A  57
GLY A  58
 None
 0.83A 2qx6A-2gj2A:
undetectable
2qx6B-2gj2A:
undetectable		 2qx6A-2gj2A:
18.39
2qx6B-2gj2A:
18.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IA4_B_MTXB164_2
(DIHYDROFOLATE
REDUCTASE)		 2gj2 WSV230
(White
spot
syndrome
virus) 		4 / 4 PHE A   4
LYS A   2
ILE A  73
THR A  52
 None
 1.25A 3ia4B-2gj2A:
undetectable		 3ia4B-2gj2A:
23.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S3V_A_TOPA193_1
(DIHYDROFOLATE
REDUCTASE)		 2gj2 WSV230
(White
spot
syndrome
virus) 		4 / 5 ASP A   9
LEU A  47
ILE A  73
PRO A  75
 CD  A 201 (-2.0A)
None
None
None
 1.15A 3s3vA-2gj2A:
undetectable		 3s3vA-2gj2A:
17.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZSF_A_6T0A910_0
(TOLL-LIKE RECEPTOR 7)		 2gj2 WSV230
(White
spot
syndrome
virus) 		4 / 7 THR A  66
ASP A  68
LEU A  71
TYR A  43
 None
 0.97A 5zsfA-2gj2A:
undetectable
5zsfB-2gj2A:
undetectable		 5zsfA-2gj2A:
18.60
5zsfB-2gj2A:
18.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DWD_A_GLYA715_0
(DEOXYNUCLEOSIDE
TRIPHOSPHATE
TRIPHOSPHOHYDROLASE
SAMHD1)		 2gj2 WSV230
(White
spot
syndrome
virus) 		4 / 6 GLY A  67
ASP A  16
SER A  18
ARG A  19
 None
 1.18A 6dwdA-2gj2A:
undetectable
6dwdC-2gj2A:
undetectable		 6dwdA-2gj2A:
10.54
6dwdC-2gj2A:
10.54