SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2gj3'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1RU9_H_ACTH611_0 (IMMUNOGLOBULIN IGG2A, HEAVY CHAIN IMMUNOGLOBULIN IGG2A, LIGHT CHAIN)	2gj3	NITROGEN FIXATION REGULATORY PROTEIN (Azotobacter vinelandii)	4 / 6	LEU A 114 ASN A 102 LEU A 73 PHE A 54	FAD A 500 (-4.3A) FAD A 500 (-3.0A) FAD A 500 (-4.2A) None	1.45A	1ru9H-2gj3A: undetectable 1ru9L-2gj3A: undetectable	1ru9H-2gj3A: 20.54 1ru9L-2gj3A: 19.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1VE3_B_SAMB301_0 (HYPOTHETICAL PROTEIN PH0226)	2gj3	NITROGEN FIXATION REGULATORY PROTEIN (Azotobacter vinelandii)	5 / 12	TYR A 110 GLY A 59 ALA A 50 ILE A 72 HIS A 133	None None None None FAD A 500 ( 4.8A)	1.09A	1ve3B-2gj3A: undetectable	1ve3B-2gj3A: 16.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5MSD_A_BEZA1202_0 (CARBOXYLIC ACID REDUCTASE)	2gj3	NITROGEN FIXATION REGULATORY PROTEIN (Azotobacter vinelandii)	4 / 5	HIS A 133 ILE A 57 SER A 39 ALA A 53	FAD A 500 ( 4.8A) None FAD A 500 ( 4.7A) None	1.27A	5msdA-2gj3A: undetectable	5msdA-2gj3A: 7.73

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1RU9_H_ACTH611_0","IMMUNOGLOBULIN IGG2A, HEAVY CHAIN;IMMUNOGLOBULIN IGG2A, LIGHT CHAIN","2gj3","NITROGEN FIXATION REGULATORY PROTEIN","Azotobacter vinelandii",4,"LEU A 114;ASN A 102;LEU A  73;PHE A  54","FAD A 500 (-4.3A);FAD A 500 (-3.0A);FAD A 500 (-4.2A);None","1.45A","1ru9H-2gj3A:undetectable;1ru9L-2gj3A:undetectable","1ru9H-2gj3A:20.54;1ru9L-2gj3A:19.34"],["1VE3_B_SAMB301_0","HYPOTHETICAL PROTEIN PH0226","2gj3","NITROGEN FIXATION REGULATORY PROTEIN","Azotobacter vinelandii",5,"TYR A 110;GLY A  59;ALA A  50;ILE A  72;HIS A 133","None;None;None;None;FAD A 500 ( 4.8A)","1.09A","1ve3B-2gj3A:undetectable","1ve3B-2gj3A:16.22"],["5MSD_A_BEZA1202_0","CARBOXYLIC ACID REDUCTASE","2gj3","NITROGEN FIXATION REGULATORY PROTEIN","Azotobacter vinelandii",4,"HIS A 133;ILE A  57;SER A  39;ALA A  53","FAD A 500 ( 4.8A);None;FAD A 500 ( 4.7A);None","1.27A","5msdA-2gj3A:undetectable","5msdA-2gj3A:7.73"]]