SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2gj4'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID
Hit
Macromolecule
Res.
Matches
Interface HETATM RMSD Dali
Z-score
Seq.
Identity (%)
View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A7Y_A_DVAA2_0
(ACTINOMYCIN D)
2gj4 GLYCOGEN
PHOSPHORYLASE,
MUSCLE FORM

(Oryctolagus
cuniculus)
4 / 4 THR A 240
PRO A 229
THR A 228
PRO A 231
SO4  A 941 ( 4.4A)
2TH  A 949 ( 4.8A)
None
None
1.34A 1a7yA-2gj4A:
undetectable
1a7yC-2gj4A:
undetectable
1a7yA-2gj4A:
1.25
1a7yC-2gj4A:
1.25
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1C8L_A_CFFA940_1
(PROTEIN (GLYCOGEN
PHOSPHORYLASE))
2gj4 GLYCOGEN
PHOSPHORYLASE,
MUSCLE FORM

(Oryctolagus
cuniculus)
6 / 6 ASN A 282
PHE A 285
HIS A 571
ALA A 610
GLY A 612
TYR A 613
None
0.52A 1c8lA-2gj4A:
55.6
1c8lA-2gj4A:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1GFZ_A_CFFA940_1
(GLYCOGEN
PHOSPHORYLASE)
2gj4 GLYCOGEN
PHOSPHORYLASE,
MUSCLE FORM

(Oryctolagus
cuniculus)
6 / 6 ASN A 282
PHE A 285
HIS A 571
ALA A 610
GLY A 612
TYR A 613
None
0.46A 1gfzA-2gj4A:
56.8
1gfzA-2gj4A:
99.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JNO_A_DVAA6_0
(GRAMICIDIN A)
2gj4 GLYCOGEN
PHOSPHORYLASE,
MUSCLE FORM

(Oryctolagus
cuniculus)
3 / 3 ALA A 818
VAL A 827
TRP A 825
None
0.93A 1jnoA-2gj4A:
undetectable
1jnoA-2gj4A:
1.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JNO_B_DVAB6_0
(GRAMICIDIN A)
2gj4 GLYCOGEN
PHOSPHORYLASE,
MUSCLE FORM

(Oryctolagus
cuniculus)
3 / 3 ALA A 818
VAL A 827
TRP A 825
None
0.93A 1jnoB-2gj4A:
undetectable
1jnoB-2gj4A:
1.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JO4_A_DVAA6_0
(GRAMICIDIN C)
2gj4 GLYCOGEN
PHOSPHORYLASE,
MUSCLE FORM

(Oryctolagus
cuniculus)
3 / 3 ALA A 818
VAL A 827
TRP A 825
None
0.93A 1jo4A-2gj4A:
undetectable
1jo4A-2gj4A:
1.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JO4_B_DVAB6_0
(GRAMICIDIN C)
2gj4 GLYCOGEN
PHOSPHORYLASE,
MUSCLE FORM

(Oryctolagus
cuniculus)
3 / 3 ALA A 818
VAL A 827
TRP A 825
None
0.93A 1jo4B-2gj4A:
undetectable
1jo4B-2gj4A:
1.83
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1L5Q_A_CFFA863_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)
2gj4 GLYCOGEN
PHOSPHORYLASE,
MUSCLE FORM

(Oryctolagus
cuniculus)
6 / 6 ASN A 282
PHE A 285
HIS A 571
ALA A 610
GLY A 612
TYR A 613
None
0.44A 1l5qA-2gj4A:
55.0
1l5qA-2gj4A:
80.87
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1L5Q_A_CFFA864_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)
2gj4 GLYCOGEN
PHOSPHORYLASE,
MUSCLE FORM

(Oryctolagus
cuniculus)
4 / 4 TRP A 174
HIS A 614
LYS A 617
MET A 618
None
0.25A 1l5qA-2gj4A:
55.0
1l5qA-2gj4A:
80.87
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1L5Q_B_CFFB1863_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)
2gj4 GLYCOGEN
PHOSPHORYLASE,
MUSCLE FORM

(Oryctolagus
cuniculus)
6 / 6 ASN A 282
PHE A 285
HIS A 571
ALA A 610
GLY A 612
TYR A 613
None
0.52A 1l5qB-2gj4A:
55.0
1l5qB-2gj4A:
80.87
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1L5Q_B_CFFB1864_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)
2gj4 GLYCOGEN
PHOSPHORYLASE,
MUSCLE FORM

(Oryctolagus
cuniculus)
3 / 3 TRP A 174
HIS A 614
MET A 618
None
0.24A 1l5qB-2gj4A:
55.0
1l5qB-2gj4A:
80.87
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1L5R_A_RBFA859_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)
2gj4 GLYCOGEN
PHOSPHORYLASE,
MUSCLE FORM

(Oryctolagus
cuniculus)
11 / 11 ASN A 282
PHE A 285
LEU A 380
GLU A 382
HIS A 571
TYR A 573
ALA A 610
GLY A 612
TYR A 613
ARG A 770
PHE A 771
None
0.83A 1l5rA-2gj4A:
54.6
1l5rA-2gj4A:
80.87
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1L5R_A_RBFA859_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)
2gj4 GLYCOGEN
PHOSPHORYLASE,
MUSCLE FORM

(Oryctolagus
cuniculus)
6 / 11 HIS A 571
TYR A 573
ALA A 609
TYR A 613
ARG A 770
PHE A 771
None
1.49A 1l5rA-2gj4A:
54.6
1l5rA-2gj4A:
80.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L7F_A_BCZA801_1
(NEURAMINIDASE)
2gj4 GLYCOGEN
PHOSPHORYLASE,
MUSCLE FORM

(Oryctolagus
cuniculus)
3 / 3 ARG A 242
ARG A  81
ARG A 193
None
None
SO4  A 941 (-3.7A)
0.93A 1l7fA-2gj4A:
undetectable
1l7fA-2gj4A:
18.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L7H_A_BCZA801_1
(NEURAMINIDASE)
2gj4 GLYCOGEN
PHOSPHORYLASE,
MUSCLE FORM

(Oryctolagus
cuniculus)
3 / 3 ARG A 242
ARG A  81
ARG A 193
None
None
SO4  A 941 (-3.7A)
0.93A 1l7hA-2gj4A:
undetectable
1l7hA-2gj4A:
18.59
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1L7X_A_CFFA863_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)
2gj4 GLYCOGEN
PHOSPHORYLASE,
MUSCLE FORM

(Oryctolagus
cuniculus)
6 / 6 ASN A 282
PHE A 285
HIS A 571
ALA A 610
GLY A 612
TYR A 613
None
0.42A 1l7xA-2gj4A:
54.5
1l7xA-2gj4A:
80.87
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1L7X_A_CFFA864_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)
2gj4 GLYCOGEN
PHOSPHORYLASE,
MUSCLE FORM

(Oryctolagus
cuniculus)
3 / 3 TRP A 174
HIS A 614
LYS A 617
None
0.22A 1l7xA-2gj4A:
54.5
1l7xA-2gj4A:
80.87
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1L7X_B_CFFB1863_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)
2gj4 GLYCOGEN
PHOSPHORYLASE,
MUSCLE FORM

(Oryctolagus
cuniculus)
6 / 6 ASN A 282
PHE A 285
HIS A 571
ALA A 610
GLY A 612
TYR A 613
None
0.46A 1l7xB-2gj4A:
54.4
1l7xB-2gj4A:
80.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NG8_A_DVAA6_0
(GRAMICIDIN A)
2gj4 GLYCOGEN
PHOSPHORYLASE,
MUSCLE FORM

(Oryctolagus
cuniculus)
3 / 3 ALA A 818
VAL A 827
TRP A 825
None
0.93A 1ng8A-2gj4A:
undetectable
1ng8A-2gj4A:
3.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NG8_B_DVAB6_0
(GRAMICIDIN A)
2gj4 GLYCOGEN
PHOSPHORYLASE,
MUSCLE FORM

(Oryctolagus
cuniculus)
3 / 3 ALA A 818
VAL A 827
TRP A 825
None
0.92A 1ng8B-2gj4A:
undetectable
1ng8B-2gj4A:
3.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NRU_A_DVAA6_0
(GRAMICIDIN A)
2gj4 GLYCOGEN
PHOSPHORYLASE,
MUSCLE FORM

(Oryctolagus
cuniculus)
3 / 3 ALA A 818
VAL A 827
TRP A 825
None
0.94A 1nruA-2gj4A:
undetectable
1nruA-2gj4A:
1.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NRU_B_DVAB6_0
(GRAMICIDIN A)
2gj4 GLYCOGEN
PHOSPHORYLASE,
MUSCLE FORM

(Oryctolagus
cuniculus)
3 / 3 ALA A 818
VAL A 827
TRP A 825
None
0.94A 1nruB-2gj4A:
undetectable
1nruB-2gj4A:
1.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q0Y_H_MOIH401_1
(FAB 9B1, HEAVY CHAIN
FAB 9B1, LIGHT CHAIN)
2gj4 GLYCOGEN
PHOSPHORYLASE,
MUSCLE FORM

(Oryctolagus
cuniculus)
4 / 7 GLU A 385
GLU A 296
TRP A 387
LEU A 392
None
1.29A 1q0yH-2gj4A:
undetectable
1q0yL-2gj4A:
undetectable
1q0yH-2gj4A:
13.43
1q0yL-2gj4A:
12.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QVU_A_PRLA196_0
(TRANSCRIPTIONAL
REGULATOR QACR)
2gj4 GLYCOGEN
PHOSPHORYLASE,
MUSCLE FORM

(Oryctolagus
cuniculus)
4 / 6 LEU A 652
GLU A 646
THR A 624
TYR A 548
None
1.48A 1qvuA-2gj4A:
undetectable
1qvuA-2gj4A:
12.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1S8F_A_BEZA1501_0
(RAS-RELATED PROTEIN
RAB-9A)
2gj4 GLYCOGEN
PHOSPHORYLASE,
MUSCLE FORM

(Oryctolagus
cuniculus)
4 / 5 ILE A 817
TRP A 825
LEU A 150
PRO A 829
None
1.46A 1s8fA-2gj4A:
7.1
1s8fB-2gj4A:
7.1
1s8fA-2gj4A:
13.26
1s8fB-2gj4A:
13.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DM6_A_IMNA1401_1
(NADP-DEPENDENT
LEUKOTRIENE B4
12-HYDROXYDEHYDROGEN
ASE)
2gj4 GLYCOGEN
PHOSPHORYLASE,
MUSCLE FORM

(Oryctolagus
cuniculus)
5 / 10 TYR A 155
ILE A  82
ALA A 153
ILE A 307
ILE A 335
None
1.31A 2dm6A-2gj4A:
3.3
2dm6B-2gj4A:
3.4
2dm6A-2gj4A:
18.31
2dm6B-2gj4A:
18.31
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2ECP_A_ACRA992_1
(MALTODEXTRIN
PHOSPHORYLASE)
2gj4 GLYCOGEN
PHOSPHORYLASE,
MUSCLE FORM

(Oryctolagus
cuniculus)
5 / 10 ASN A 133
LEU A 136
ASP A 339
HIS A 341
ALA A 610
None
1.00A 2ecpA-2gj4A:
45.9
2ecpA-2gj4A:
43.71
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2ECP_B_ACRB992_1
(MALTODEXTRIN
PHOSPHORYLASE)
2gj4 GLYCOGEN
PHOSPHORYLASE,
MUSCLE FORM

(Oryctolagus
cuniculus)
5 / 10 ASN A 133
LEU A 136
ASP A 339
HIS A 341
ALA A 610
None
0.98A 2ecpB-2gj4A:
45.9
2ecpB-2gj4A:
43.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EJ3_C_GBNC1414_1
(BRANCHED-CHAIN AMINO
ACID
AMINOTRANSFERASE)
2gj4 GLYCOGEN
PHOSPHORYLASE,
MUSCLE FORM

(Oryctolagus
cuniculus)
5 / 8 ARG A 309
GLU A 348
THR A 303
ALA A 302
ALA A 301
None
1.40A 2ej3C-2gj4A:
undetectable
2ej3C-2gj4A:
17.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HMA_A_SAMA375_0
(PROBABLE TRNA
(5-METHYLAMINOMETHYL
-2-THIOURIDYLATE)-ME
THYLTRANSFERASE)
2gj4 GLYCOGEN
PHOSPHORYLASE,
MUSCLE FORM

(Oryctolagus
cuniculus)
5 / 11 GLY A 135
ASP A 693
THR A 676
GLY A 677
GLN A 665
PLR  A 940 ( 3.8A)
None
PLR  A 940 (-4.5A)
PLR  A 940 (-3.8A)
PLR  A 940 ( 4.4A)
1.47A 2hmaA-2gj4A:
undetectable
2hmaA-2gj4A:
18.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2M9Q_B_BEZB251_0
(SERINE PROTEASE
INHIBITOR
SERINE PROTEASE
SUBUNIT NS2B, SERINE
PROTEASE NS3)
2gj4 GLYCOGEN
PHOSPHORYLASE,
MUSCLE FORM

(Oryctolagus
cuniculus)
5 / 9 ILE A 308
ILE A 307
PHE A 326
THR A 371
LEU A 353
None
1.19A 2m9qA-2gj4A:
undetectable
2m9qA-2gj4A:
14.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2O4N_A_TPVA300_2
(PROTEASE)
2gj4 GLYCOGEN
PHOSPHORYLASE,
MUSCLE FORM

(Oryctolagus
cuniculus)
4 / 8 LEU A 499
GLY A 508
ILE A 507
LEU A 492
None
0.68A 2o4nB-2gj4A:
undetectable
2o4nB-2gj4A:
8.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q6F_C_010C6_0
(INFECTIOUS
BRONCHITIS VIRUS
(IBV) MAIN PROTEASE
N-[(5-METHYLISOXAZOL
-3-YL)CARBONYL]ALANY
L-L-VALYL-N~1~-((1R,
2Z)-4-(BENZYLOXY)-4-
OXO-1-{[(3R)-2-OXOPY
RROLIDIN-3-YL]METHYL
}BUT-2-ENYL)-L-LEUCI
NAMIDE)
2gj4 GLYCOGEN
PHOSPHORYLASE,
MUSCLE FORM

(Oryctolagus
cuniculus)
3 / 3 ASN A 133
LEU A 136
HIS A 341
None
0.87A 2q6fB-2gj4A:
undetectable
2q6fB-2gj4A:
17.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W9H_A_TOPA1160_1
(DIHYDROFOLATE
REDUCTASE)
2gj4 GLYCOGEN
PHOSPHORYLASE,
MUSCLE FORM

(Oryctolagus
cuniculus)
5 / 10 LEU A 474
ALA A 447
LEU A 430
LEU A 411
VAL A 414
None
None
None
SO4  A 948 (-3.9A)
None
1.03A 2w9hA-2gj4A:
undetectable
2w9hA-2gj4A:
11.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WM3_A_NFLA1301_1
(NMRA-LIKE FAMILY
DOMAIN CONTAINING
PROTEIN 1)
2gj4 GLYCOGEN
PHOSPHORYLASE,
MUSCLE FORM

(Oryctolagus
cuniculus)
4 / 6 LEU A 117
PHE A  31
LEU A  55
ASP A  50
None
0.84A 2wm3A-2gj4A:
3.3
2wm3A-2gj4A:
17.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZS9_A_PAUA603_0
(PANTOTHENATE KINASE)
2gj4 GLYCOGEN
PHOSPHORYLASE,
MUSCLE FORM

(Oryctolagus
cuniculus)
4 / 6 VAL A 455
ASP A 339
TYR A  84
ASN A 484
None
1.45A 2zs9A-2gj4A:
undetectable
2zs9A-2gj4A:
18.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ARU_A_PNXA607_1
(CHITINASE A)
2gj4 GLYCOGEN
PHOSPHORYLASE,
MUSCLE FORM

(Oryctolagus
cuniculus)
5 / 8 GLY A 675
THR A 676
GLU A 672
GLY A 694
ALA A 695
PLR  A 940 (-3.3A)
PLR  A 940 (-4.5A)
PLR  A 940 ( 4.5A)
None
None
1.09A 3aruA-2gj4A:
2.2
3aruA-2gj4A:
21.15
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3BCR_A_AZZA940_1
(GLYCOGEN
PHOSPHORYLASE,
MUSCLE FORM)
2gj4 GLYCOGEN
PHOSPHORYLASE,
MUSCLE FORM

(Oryctolagus
cuniculus)
5 / 5 ASN A 282
PHE A 285
ALA A 610
GLY A 612
TYR A 613
None
0.36A 3bcrA-2gj4A:
57.4
3bcrA-2gj4A:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3DD1_A_CFFA903_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)
2gj4 GLYCOGEN
PHOSPHORYLASE,
MUSCLE FORM

(Oryctolagus
cuniculus)
6 / 6 ASN A 282
PHE A 285
HIS A 571
ALA A 610
GLY A 612
TYR A 613
None
0.47A 3dd1A-2gj4A:
54.0
3dd1A-2gj4A:
80.87
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3DD1_B_CFFB903_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)
2gj4 GLYCOGEN
PHOSPHORYLASE,
MUSCLE FORM

(Oryctolagus
cuniculus)
6 / 6 ASN A 282
PHE A 285
HIS A 571
ALA A 610
GLY A 612
TYR A 613
None
0.45A 3dd1B-2gj4A:
54.0
3dd1B-2gj4A:
80.87
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3DDS_A_CFFA904_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)
2gj4 GLYCOGEN
PHOSPHORYLASE,
MUSCLE FORM

(Oryctolagus
cuniculus)
6 / 6 ASN A 282
PHE A 285
HIS A 571
ALA A 610
GLY A 612
TYR A 613
None
0.49A 3ddsA-2gj4A:
54.2
3ddsA-2gj4A:
80.87
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3DDS_B_CFFB903_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)
2gj4 GLYCOGEN
PHOSPHORYLASE,
MUSCLE FORM

(Oryctolagus
cuniculus)
6 / 6 ASN A 282
PHE A 285
HIS A 571
ALA A 610
GLY A 612
TYR A 613
None
0.50A 3ddsB-2gj4A:
54.4
3ddsB-2gj4A:
80.87
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3DDW_A_CFFA903_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)
2gj4 GLYCOGEN
PHOSPHORYLASE,
MUSCLE FORM

(Oryctolagus
cuniculus)
6 / 6 ASN A 282
PHE A 285
HIS A 571
ALA A 610
GLY A 612
TYR A 613
None
0.47A 3ddwA-2gj4A:
54.1
3ddwA-2gj4A:
80.87
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3DDW_B_CFFB903_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)
2gj4 GLYCOGEN
PHOSPHORYLASE,
MUSCLE FORM

(Oryctolagus
cuniculus)
6 / 6 ASN A 282
PHE A 285
HIS A 571
ALA A 610
GLY A 612
TYR A 613
None
0.48A 3ddwB-2gj4A:
54.4
3ddwB-2gj4A:
80.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FRB_X_TOPX300_1
(DIHYDROFOLATE
REDUCTASE)
2gj4 GLYCOGEN
PHOSPHORYLASE,
MUSCLE FORM

(Oryctolagus
cuniculus)
5 / 11 LEU A 474
ALA A 447
LEU A 430
LEU A 411
VAL A 414
None
None
None
SO4  A 948 (-3.9A)
None
1.07A 3frbX-2gj4A:
undetectable
3frbX-2gj4A:
12.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3H9U_B_ADNB438_1
(ADENOSYLHOMOCYSTEINA
SE)
2gj4 GLYCOGEN
PHOSPHORYLASE,
MUSCLE FORM

(Oryctolagus
cuniculus)
5 / 10 THR A 671
THR A 668
ASN A 284
LEU A 380
HIS A 571
None
1.16A 3h9uB-2gj4A:
5.5
3h9uB-2gj4A:
19.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LP9_D_SPMD230_1
(LS-24)
2gj4 GLYCOGEN
PHOSPHORYLASE,
MUSCLE FORM

(Oryctolagus
cuniculus)
3 / 3 GLU A 672
GLU A 382
ASN A 284
PLR  A 940 ( 4.5A)
None
None
0.88A 3lp9B-2gj4A:
undetectable
3lp9D-2gj4A:
undetectable
3lp9B-2gj4A:
14.09
3lp9D-2gj4A:
14.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MJR_A_AC2A301_1
(DEOXYCYTIDINE KINASE)
2gj4 GLYCOGEN
PHOSPHORYLASE,
MUSCLE FORM

(Oryctolagus
cuniculus)
5 / 9 ILE A 507
GLU A 505
ASP A 533
PHE A 530
LEU A 521
None
1.43A 3mjrA-2gj4A:
0.0
3mjrA-2gj4A:
16.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3THR_A_C2FA1100_0
(GLYCINE
N-METHYLTRANSFERASE)
2gj4 GLYCOGEN
PHOSPHORYLASE,
MUSCLE FORM

(Oryctolagus
cuniculus)
4 / 6 SER A 812
LEU A 683
THR A 487
ARG A 489
None
1.40A 3thrB-2gj4A:
undetectable
3thrB-2gj4A:
15.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VW7_A_VPXA2001_1
(PROTEINASE-ACTIVATED
RECEPTOR 1, LYSOZYME)
2gj4 GLYCOGEN
PHOSPHORYLASE,
MUSCLE FORM

(Oryctolagus
cuniculus)
5 / 12 LEU A 384
LEU A 463
ALA A 451
ALA A 373
TYR A 374
None
1.10A 3vw7A-2gj4A:
undetectable
3vw7A-2gj4A:
19.91
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4BQF_A_QPSA951_1
(ALPHA-GLUCAN
PHOSPHORYLASE 2,
CYTOSOLIC)
2gj4 GLYCOGEN
PHOSPHORYLASE,
MUSCLE FORM

(Oryctolagus
cuniculus)
4 / 6 TRP A 361
ARG A 398
GLU A 405
ARG A 409
None
0.59A 4bqfA-2gj4A:
46.9
4bqfA-2gj4A:
45.35
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4BQF_B_QPSB951_1
(ALPHA-GLUCAN
PHOSPHORYLASE 2,
CYTOSOLIC)
2gj4 GLYCOGEN
PHOSPHORYLASE,
MUSCLE FORM

(Oryctolagus
cuniculus)
4 / 8 TRP A 361
ARG A 398
GLU A 405
ARG A 409
None
0.55A 4bqfB-2gj4A:
46.8
4bqfB-2gj4A:
45.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D33_A_MTLA870_0
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
2gj4 GLYCOGEN
PHOSPHORYLASE,
MUSCLE FORM

(Oryctolagus
cuniculus)
4 / 8 ASN A 440
GLU A 385
ASN A 376
ASP A 339
None
1.10A 4d33A-2gj4A:
undetectable
4d33A-2gj4A:
20.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D33_B_MTLB870_0
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
2gj4 GLYCOGEN
PHOSPHORYLASE,
MUSCLE FORM

(Oryctolagus
cuniculus)
4 / 7 ASN A 440
GLU A 385
ASN A 376
ASP A 339
None
1.10A 4d33B-2gj4A:
undetectable
4d33B-2gj4A:
20.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D39_A_MTLA870_0
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
2gj4 GLYCOGEN
PHOSPHORYLASE,
MUSCLE FORM

(Oryctolagus
cuniculus)
4 / 8 ASN A 440
GLU A 385
ASN A 376
ASP A 339
None
1.04A 4d39A-2gj4A:
undetectable
4d39A-2gj4A:
20.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D39_B_MTLB870_0
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
2gj4 GLYCOGEN
PHOSPHORYLASE,
MUSCLE FORM

(Oryctolagus
cuniculus)
4 / 7 ASN A 440
GLU A 385
ASN A 376
ASP A 339
None
1.08A 4d39B-2gj4A:
undetectable
4d39B-2gj4A:
20.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EYZ_A_CCSA109_0
(CELLULOSOME-RELATED
PROTEIN MODULE FROM
RUMINOCOCCUS
FLAVEFACIENS THAT
RESEMBLES
PAPAIN-LIKE CYSTEINE
PEPTIDASES)
2gj4 GLYCOGEN
PHOSPHORYLASE,
MUSCLE FORM

(Oryctolagus
cuniculus)
5 / 8 ASN A 481
PHE A 479
VAL A 452
HIS A 459
ALA A 673
None
1.35A 4eyzA-2gj4A:
undetectable
4eyzA-2gj4A:
14.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EYZ_B_CCSB109_0
(CELLULOSOME-RELATED
PROTEIN MODULE FROM
RUMINOCOCCUS
FLAVEFACIENS THAT
RESEMBLES
PAPAIN-LIKE CYSTEINE
PEPTIDASES)
2gj4 GLYCOGEN
PHOSPHORYLASE,
MUSCLE FORM

(Oryctolagus
cuniculus)
5 / 8 ASN A 481
PHE A 479
VAL A 452
HIS A 459
ALA A 673
None
1.33A 4eyzB-2gj4A:
undetectable
4eyzB-2gj4A:
14.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KT0_A_PQNA2001_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1
PHOTOSYSTEM I
REACTION CENTER
SUBUNIT IX)
2gj4 GLYCOGEN
PHOSPHORYLASE,
MUSCLE FORM

(Oryctolagus
cuniculus)
5 / 11 GLY A 135
ARG A 138
ALA A 141
GLY A 132
LEU A 198
PLR  A 940 ( 3.8A)
None
None
None
None
1.06A 4kt0A-2gj4A:
undetectable
4kt0J-2gj4A:
undetectable
4kt0A-2gj4A:
22.56
4kt0J-2gj4A:
4.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5C0O_H_SAMH301_0
(TRNA
(ADENINE(58)-N(1))-M
ETHYLTRANSFERASE
TRMI)
2gj4 GLYCOGEN
PHOSPHORYLASE,
MUSCLE FORM

(Oryctolagus
cuniculus)
5 / 12 ALA A 140
GLY A 132
GLY A 137
GLY A 135
LEU A 131
None
None
None
PLR  A 940 ( 3.8A)
None
0.80A 5c0oH-2gj4A:
undetectable
5c0oH-2gj4A:
15.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HYR_A_ESTA601_1
(ESTROGEN RECEPTOR)
2gj4 GLYCOGEN
PHOSPHORYLASE,
MUSCLE FORM

(Oryctolagus
cuniculus)
5 / 10 LEU A 222
ALA A 246
GLU A 273
ARG A 269
HIS A 201
None
None
None
None
SO4  A 942 ( 3.9A)
1.49A 5hyrA-2gj4A:
undetectable
5hyrA-2gj4A:
15.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KC4_E_RBFE201_2
(RIBOFLAVIN
TRANSPORTER RIBU)
2gj4 GLYCOGEN
PHOSPHORYLASE,
MUSCLE FORM

(Oryctolagus
cuniculus)
3 / 3 LYS A 608
ASP A 283
ILE A 623
None
0.81A 5kc4E-2gj4A:
undetectable
5kc4E-2gj4A:
12.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N5D_A_SAMA306_1
(METHYLTRANSFERASE)
2gj4 GLYCOGEN
PHOSPHORYLASE,
MUSCLE FORM

(Oryctolagus
cuniculus)
4 / 7 LEU A 652
ILE A 125
GLU A 124
ASP A 128
None
0.96A 5n5dA-2gj4A:
3.1
5n5dA-2gj4A:
13.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TUD_D_ERMD1201_2
(5-HYDROXYTRYPTAMINE
RECEPTOR 2B,SOLUBLE
CYTOCHROME B562
CHIMERA)
2gj4 GLYCOGEN
PHOSPHORYLASE,
MUSCLE FORM

(Oryctolagus
cuniculus)
4 / 6 LEU A 198
VAL A 200
LEU A 349
GLU A 357
None
0.85A 5tudD-2gj4A:
undetectable
5tudD-2gj4A:
19.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UIG_A_EDTA501_0
(ADENOSINE RECEPTOR
A2A,SOLUBLE
CYTOCHROME
B562,ADENOSINE
RECEPTOR A2A)
2gj4 GLYCOGEN
PHOSPHORYLASE,
MUSCLE FORM

(Oryctolagus
cuniculus)
4 / 6 ASN A 696
THR A 691
ILE A 458
GLU A 698
None
1.35A 5uigA-2gj4A:
undetectable
5uigA-2gj4A:
17.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VNC_C_GCSC801_1
(GLYCOGEN [STARCH]
SYNTHASE ISOFORM 2)
2gj4 GLYCOGEN
PHOSPHORYLASE,
MUSCLE FORM

(Oryctolagus
cuniculus)
7 / 10 GLY A 135
HIS A 377
VAL A 455
ASN A 484
LYS A 574
GLU A 672
GLY A 675
PLR  A 940 ( 3.8A)
None
None
None
PLR  A 940 (-2.8A)
PLR  A 940 ( 4.5A)
PLR  A 940 (-3.3A)
0.70A 5vncC-2gj4A:
18.0
5vncC-2gj4A:
6.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6D8F_A_ACTA803_0
(UNCHARACTERIZED
PROTEIN)
2gj4 GLYCOGEN
PHOSPHORYLASE,
MUSCLE FORM

(Oryctolagus
cuniculus)
3 / 3 GLU A 778
LEU A 738
ARG A 739
None
0.78A 6d8fA-2gj4A:
2.1
6d8fA-2gj4A:
22.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EXI_A_ADNA502_0
(ADENOSYLHOMOCYSTEINA
SE)
2gj4 GLYCOGEN
PHOSPHORYLASE,
MUSCLE FORM

(Oryctolagus
cuniculus)
5 / 12 THR A 671
THR A 668
ASN A 284
LEU A 380
HIS A 571
None
1.17A 6exiA-2gj4A:
4.9
6exiA-2gj4A:
7.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EXI_B_ADNB502_0
(ADENOSYLHOMOCYSTEINA
SE)
2gj4 GLYCOGEN
PHOSPHORYLASE,
MUSCLE FORM

(Oryctolagus
cuniculus)
5 / 12 THR A 671
THR A 668
ASN A 284
LEU A 380
HIS A 571
None
1.16A 6exiB-2gj4A:
2.3
6exiB-2gj4A:
7.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EXI_C_ADNC502_0
(ADENOSYLHOMOCYSTEINA
SE)
2gj4 GLYCOGEN
PHOSPHORYLASE,
MUSCLE FORM

(Oryctolagus
cuniculus)
5 / 12 THR A 671
THR A 668
ASN A 284
LEU A 380
HIS A 571
None
1.15A 6exiC-2gj4A:
4.9
6exiC-2gj4A:
7.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EXI_D_ADND502_0
(ADENOSYLHOMOCYSTEINA
SE)
2gj4 GLYCOGEN
PHOSPHORYLASE,
MUSCLE FORM

(Oryctolagus
cuniculus)
5 / 12 THR A 671
THR A 668
ASN A 284
LEU A 380
HIS A 571
None
1.16A 6exiD-2gj4A:
3.7
6exiD-2gj4A:
7.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GNE_A_ACRA602_1
(-)
2gj4 GLYCOGEN
PHOSPHORYLASE,
MUSCLE FORM

(Oryctolagus
cuniculus)
6 / 12 GLY A 134
GLY A 135
ASP A 339
VAL A 455
ASN A 484
GLY A 675
PLR  A 940 (-3.6A)
PLR  A 940 ( 3.8A)
None
None
None
PLR  A 940 (-3.3A)
0.69A 6gneA-2gj4A:
22.8
6gneA-2gj4A:
20.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GNE_B_ACRB602_1
(-)
2gj4 GLYCOGEN
PHOSPHORYLASE,
MUSCLE FORM

(Oryctolagus
cuniculus)
7 / 12 GLU A  88
GLY A 134
GLY A 135
ASP A 339
VAL A 455
ASN A 484
GLY A 675
None
PLR  A 940 (-3.6A)
PLR  A 940 ( 3.8A)
None
None
None
PLR  A 940 (-3.3A)
0.78A 6gneB-2gj4A:
22.8
6gneB-2gj4A:
20.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GNF_A_QPSA602_1
(-)
2gj4 GLYCOGEN
PHOSPHORYLASE,
MUSCLE FORM

(Oryctolagus
cuniculus)
5 / 12 ASP A 339
HIS A 341
ASN A 484
GLU A 672
GLY A 675
None
None
None
PLR  A 940 ( 4.5A)
PLR  A 940 (-3.3A)
0.77A 6gnfA-2gj4A:
21.6
6gnfA-2gj4A:
21.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GNF_C_QPSC602_2
(-)
2gj4 GLYCOGEN
PHOSPHORYLASE,
MUSCLE FORM

(Oryctolagus
cuniculus)
5 / 12 ASP A 339
HIS A 341
ASN A 484
GLU A 672
GLY A 675
None
None
None
PLR  A 940 ( 4.5A)
PLR  A 940 (-3.3A)
0.76A 6gnfC-2gj4A:
21.9
6gnfC-2gj4A:
21.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GNG_A_QPSA601_1
(-)
2gj4 GLYCOGEN
PHOSPHORYLASE,
MUSCLE FORM

(Oryctolagus
cuniculus)
5 / 12 GLY A 134
LEU A 136
ASP A 339
HIS A 341
ASN A 484
PLR  A 940 (-3.6A)
None
None
None
None
0.88A 6gngA-2gj4A:
21.8
6gngA-2gj4A:
21.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GNG_A_QPSA601_2
(-)
2gj4 GLYCOGEN
PHOSPHORYLASE,
MUSCLE FORM

(Oryctolagus
cuniculus)
6 / 12 GLU A  88
GLY A 135
HIS A 377
VAL A 455
GLU A 672
GLY A 675
None
PLR  A 940 ( 3.8A)
None
None
PLR  A 940 ( 4.5A)
PLR  A 940 (-3.3A)
0.72A 6gngA-2gj4A:
21.8
6gngA-2gj4A:
21.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GNG_B_QPSB601_2
(-)
2gj4 GLYCOGEN
PHOSPHORYLASE,
MUSCLE FORM

(Oryctolagus
cuniculus)
5 / 12 GLU A  88
GLY A 134
GLY A 135
GLY A 612
ASN A 284
None
PLR  A 940 (-3.6A)
PLR  A 940 ( 3.8A)
None
None
1.03A 6gngB-2gj4A:
21.8
6gngB-2gj4A:
21.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GNG_B_QPSB601_2
(-)
2gj4 GLYCOGEN
PHOSPHORYLASE,
MUSCLE FORM

(Oryctolagus
cuniculus)
6 / 12 GLU A  88
GLY A 134
GLY A 135
LEU A 136
HIS A 341
ASN A 284
None
PLR  A 940 (-3.6A)
PLR  A 940 ( 3.8A)
None
None
None
1.12A 6gngB-2gj4A:
21.8
6gngB-2gj4A:
21.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GNG_B_QPSB601_2
(-)
2gj4 GLYCOGEN
PHOSPHORYLASE,
MUSCLE FORM

(Oryctolagus
cuniculus)
5 / 12 GLU A  88
GLY A 134
LEU A 136
HIS A 341
ASN A 284
None
PLR  A 940 (-3.6A)
None
None
None
1.07A 6gngB-2gj4A:
21.8
6gngB-2gj4A:
21.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HQB_A_PQNA2001_0
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1
PHOTOSYSTEM I
REACTION CENTER
SUBUNIT IX)
2gj4 GLYCOGEN
PHOSPHORYLASE,
MUSCLE FORM

(Oryctolagus
cuniculus)
5 / 10 GLY A 135
ARG A 138
ALA A 141
GLY A 132
LEU A 198
PLR  A 940 ( 3.8A)
None
None
None
None
1.05A 6hqbA-2gj4A:
undetectable
6hqbJ-2gj4A:
undetectable
6hqbA-2gj4A:
6.92
6hqbJ-2gj4A:
4.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HZP_A_FVTA501_0
(PEPTIDE ABC
TRANSPORTER PERMEASE)
2gj4 GLYCOGEN
PHOSPHORYLASE,
MUSCLE FORM

(Oryctolagus
cuniculus)
4 / 8 VAL A 629
GLN A 740
ASN A 588
ILE A 584
None
1.01A 6hzpA-2gj4A:
undetectable
6hzpA-2gj4A:
21.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6JI6_A_ACTA305_0
(GLUTATHIONE
S-TRANSFERASE
CLASS-MU 26 KDA
ISOZYME)
2gj4 GLYCOGEN
PHOSPHORYLASE,
MUSCLE FORM

(Oryctolagus
cuniculus)
4 / 5 GLY A 137
LEU A 136
SER A  86
TYR A  84
None
0.95A 6ji6A-2gj4A:
undetectable
6ji6A-2gj4A:
14.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MA7_A_TPFA602_0
(CYTOCHROME P450 3A4)
2gj4 GLYCOGEN
PHOSPHORYLASE,
MUSCLE FORM

(Oryctolagus
cuniculus)
4 / 7 ARG A 398
ALA A 364
THR A 368
ILE A 346
None
0.97A 6ma7A-2gj4A:
undetectable
6ma7A-2gj4A:
7.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MN4_C_AM2C301_0
(AMINOGLYCOSIDE
N(3)-ACETYLTRANSFERA
SE, AAC(3)-IVA)
2gj4 GLYCOGEN
PHOSPHORYLASE,
MUSCLE FORM

(Oryctolagus
cuniculus)
4 / 8 ASP A 339
HIS A 443
HIS A 341
GLU A 382
None
1.15A 6mn4C-2gj4A:
undetectable
6mn4C-2gj4A:
16.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NJ9_K_SAMK500_1
(HISTONE-LYSINE
N-METHYLTRANSFERASE,
H3 LYSINE-79
SPECIFIC)
2gj4 GLYCOGEN
PHOSPHORYLASE,
MUSCLE FORM

(Oryctolagus
cuniculus)
3 / 3 THR A 378
GLU A  88
ASN A 284
None
0.56A 6nj9K-2gj4A:
4.0
6nj9K-2gj4A:
20.07