SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2gj7'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SS4_A_ACTA411_0
(GLYOXALASE FAMILY
PROTEIN)		 2gj7 GLYCOPROTEIN E
(Human
alphaherpesvirus
1) 		4 / 5 TRP F 262
VAL F 244
THR F 228
ILE F 375
 None
 1.37A 1ss4A-2gj7F:
0.0		 1ss4A-2gj7F:
17.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3R9S_A_BEZA264_0
(CARNITINYL-COA
DEHYDRATASE)		 2gj7 GLYCOPROTEIN E
(Human
alphaherpesvirus
1) 		4 / 6 ALA F 384
ILE F 276
LEU F 356
ALA F 231
 None
 0.65A 3r9sA-2gj7F:
undetectable		 3r9sA-2gj7F:
22.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3R9S_C_BEZC264_0
(CARNITINYL-COA
DEHYDRATASE)		 2gj7 GLYCOPROTEIN E
(Human
alphaherpesvirus
1) 		4 / 6 ALA F 384
ILE F 276
LEU F 356
ALA F 231
 None
 0.66A 3r9sC-2gj7F:
undetectable		 3r9sC-2gj7F:
22.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3R9T_A_BEZA264_0
(ECHA1_1)		 2gj7 GLYCOPROTEIN E
(Human
alphaherpesvirus
1) 		4 / 8 ALA F 384
ILE F 276
LEU F 356
ALA F 231
 None
 0.69A 3r9tA-2gj7F:
undetectable		 3r9tA-2gj7F:
22.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FFW_B_715B801_2
(DIPEPTIDYL PEPTIDASE
4)		 2gj7 GLYCOPROTEIN E
(Human
alphaherpesvirus
1) 		3 / 3 ARG F 316
TYR F 311
ASN F 364
 None
 0.66A 4ffwB-2gj7F:
undetectable		 4ffwB-2gj7F:
19.21