SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2gjm'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FM9_A_9CRA201_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 2gjm LACTOPEROXIDASE
(Bubalus
bubalis) 		6 / 12 ILE A 478
LEU A 467
ARG A 426
LEU A 422
ALA A  61
LEU A 460
 None
 1.22A 1fm9A-2gjmA:
undetectable		 1fm9A-2gjmA:
16.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HXB_A_ROCA100_2
(HIV-1 PROTEASE)		 2gjm LACTOPEROXIDASE
(Bubalus
bubalis) 		3 / 3 ARG A 239
THR A 168
VAL A 167
 HEM  A 605 (-4.7A)
CA  A1503 (-3.8A)
None
 1.02A 1hxbA-2gjmA:
undetectable		 1hxbA-2gjmA:
11.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ICU_D_NIOD223_1
(OXYGEN-INSENSITIVE
NAD(P)H
NITROREDUCTASE)		 2gjm LACTOPEROXIDASE
(Bubalus
bubalis) 		4 / 5 PHE A 334
GLY A  90
SER A 389
PHE A  86
 HEM  A 605 ( 4.7A)
HEM  A 605 (-3.4A)
None
None
 1.29A 1icuC-2gjmA:
undetectable
1icuD-2gjmA:
undetectable		 1icuC-2gjmA:
16.78
1icuD-2gjmA:
16.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RQP_A_SAMA500_1
(5'-FLUORO-5'-DEOXYAD
ENOSINE SYNTHASE)		 2gjm LACTOPEROXIDASE
(Bubalus
bubalis) 		4 / 7 ASP A 134
PHE A 130
SER A  65
ARG A 403
 None
 1.22A 1rqpB-2gjmA:
undetectable		 1rqpB-2gjmA:
18.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RQP_C_SAMC500_0
(5'-FLUORO-5'-DEOXYAD
ENOSINE SYNTHASE)		 2gjm LACTOPEROXIDASE
(Bubalus
bubalis) 		4 / 8 ASP A 134
PHE A 130
SER A  65
ARG A 403
 None
 1.17A 1rqpA-2gjmA:
undetectable		 1rqpA-2gjmA:
18.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WU8_C_ADNC502_1
(HYPOTHETICAL PROTEIN
PH0463)		 2gjm LACTOPEROXIDASE
(Bubalus
bubalis) 		4 / 7 ASN A  16
TYR A 316
ASN A 317
ARG A  18
 None
None
NAG  A 588 (-1.9A)
None
 1.40A 1wu8A-2gjmA:
undetectable
1wu8C-2gjmA:
undetectable		 1wu8A-2gjmA:
18.82
1wu8C-2gjmA:
18.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XLS_A_9CRA801_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 2gjm LACTOPEROXIDASE
(Bubalus
bubalis) 		6 / 12 ILE A 478
LEU A 467
ARG A 426
LEU A 422
ALA A  61
LEU A 460
 None
 1.21A 1xlsA-2gjmA:
undetectable		 1xlsA-2gjmA:
16.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XLS_B_9CRB802_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 2gjm LACTOPEROXIDASE
(Bubalus
bubalis) 		6 / 12 ILE A 478
LEU A 467
ARG A 426
LEU A 422
ALA A  61
LEU A 460
 None
 1.22A 1xlsB-2gjmA:
undetectable		 1xlsB-2gjmA:
16.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XLS_C_9CRC803_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 2gjm LACTOPEROXIDASE
(Bubalus
bubalis) 		6 / 12 ILE A 478
LEU A 467
ARG A 426
LEU A 422
ALA A  61
LEU A 460
 None
 1.22A 1xlsC-2gjmA:
undetectable		 1xlsC-2gjmA:
16.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XLS_D_9CRD804_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 2gjm LACTOPEROXIDASE
(Bubalus
bubalis) 		6 / 12 ILE A 478
LEU A 467
ARG A 426
LEU A 422
ALA A  61
LEU A 460
 None
 1.22A 1xlsD-2gjmA:
undetectable		 1xlsD-2gjmA:
16.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F16_2_BO221405_1
(PROTEASOME COMPONENT
PRE3)		 2gjm LACTOPEROXIDASE
(Bubalus
bubalis) 		5 / 11 THR A 168
THR A  11
ARG A 281
SER A 174
GLY A 178
 CA  A1503 (-3.8A)
None
None
CA  A1503 (-2.6A)
None
 1.22A 2f162-2gjmA:
undetectable		 2f162-2gjmA:
14.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F16_N_BO2N1404_1
(PROTEASOME COMPONENT
PRE3)		 2gjm LACTOPEROXIDASE
(Bubalus
bubalis) 		5 / 11 THR A 168
THR A  11
ARG A 281
SER A 174
GLY A 178
 CA  A1503 (-3.8A)
None
None
CA  A1503 (-2.6A)
None
 1.22A 2f16N-2gjmA:
undetectable		 2f16N-2gjmA:
14.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NXE_A_SAMA302_1
(RIBOSOMAL PROTEIN
L11
METHYLTRANSFERASE)		 2gjm LACTOPEROXIDASE
(Bubalus
bubalis) 		3 / 3 THR A 292
ASP A  98
SER A 325
 None
HEM  A 605 (-3.7A)
None
 0.80A 2nxeA-2gjmA:
undetectable		 2nxeA-2gjmA:
18.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NXE_B_SAMB303_1
(RIBOSOMAL PROTEIN
L11
METHYLTRANSFERASE)		 2gjm LACTOPEROXIDASE
(Bubalus
bubalis) 		3 / 3 THR A 292
ASP A  98
SER A 325
 None
HEM  A 605 (-3.7A)
None
 0.74A 2nxeB-2gjmA:
undetectable		 2nxeB-2gjmA:
18.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q64_B_1UNB1001_2
(PROTEASE RETROPEPSIN)		 2gjm LACTOPEROXIDASE
(Bubalus
bubalis) 		3 / 3 ARG A 239
THR A 168
VAL A 167
 HEM  A 605 (-4.7A)
CA  A1503 (-3.8A)
None
 0.89A 2q64A-2gjmA:
undetectable		 2q64A-2gjmA:
12.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QAK_A_1UNA1001_2
(PROTEASE RETROPEPSIN)		 2gjm LACTOPEROXIDASE
(Bubalus
bubalis) 		3 / 3 ARG A 239
THR A 168
VAL A 167
 HEM  A 605 (-4.7A)
CA  A1503 (-3.8A)
None
 0.88A 2qakA-2gjmA:
undetectable		 2qakA-2gjmA:
12.19
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2QQT_A_AINA596_1
(LACTOPEROXIDASE)		 2gjm LACTOPEROXIDASE
(Bubalus
bubalis) 		6 / 6 HIS A  95
ARG A 239
GLU A 242
PHE A 366
GLN A 408
PRO A 409
 SCN  A1502 ( 4.8A)
HEM  A 605 (-4.7A)
HEM  A 605 ( 2.2A)
None
HEM  A 605 ( 4.6A)
None
 0.38A 2qqtA-2gjmA:
65.6		 2qqtA-2gjmA:
99.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V7U_B_SAMB1299_1
(5'-FLUORO-5'-DEOXY
ADENOSINE SYNTHETASE)		 2gjm LACTOPEROXIDASE
(Bubalus
bubalis) 		4 / 7 ASP A 134
PHE A 130
SER A  65
ARG A 403
 None
 1.25A 2v7uB-2gjmA:
undetectable		 2v7uB-2gjmA:
18.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XFH_A_CL6A1414_1
(ERYTHROMYCIN B/D
C-12 HYDROXYLASE)		 2gjm LACTOPEROXIDASE
(Bubalus
bubalis) 		5 / 8 MET A 397
LEU A 451
ILE A 474
LEU A 464
LEU A 455
 None
 1.26A 2xfhA-2gjmA:
undetectable		 2xfhA-2gjmA:
21.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XKW_A_P1BA1478_2
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 2gjm LACTOPEROXIDASE
(Bubalus
bubalis) 		4 / 7 LEU A 572
ILE A 283
ALA A 184
ILE A  10
 None
 0.73A 2xkwA-2gjmA:
undetectable		 2xkwA-2gjmA:
20.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3F78_A_ICFA1_1
(INTEGRIN ALPHA-L)		 2gjm LACTOPEROXIDASE
(Bubalus
bubalis) 		5 / 9 ILE A 288
ILE A 291
GLU A 256
LEU A 253
TYR A 177
 None
 1.19A 3f78A-2gjmA:
undetectable		 3f78A-2gjmA:
14.46
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3GCL_A_AINA609_1
(LACTOPEROXIDASE)		 2gjm LACTOPEROXIDASE
(Bubalus
bubalis) 		6 / 6 HIS A  95
ARG A 239
GLU A 242
PHE A 366
GLN A 408
PRO A 409
 SCN  A1502 ( 4.8A)
HEM  A 605 (-4.7A)
HEM  A 605 ( 2.2A)
None
HEM  A 605 ( 4.6A)
None
 0.52A 3gclA-2gjmA:
61.4		 3gclA-2gjmA:
99.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MG0_N_BO2N1404_1
(PROTEASOME COMPONENT
PRE3)		 2gjm LACTOPEROXIDASE
(Bubalus
bubalis) 		5 / 11 THR A 168
THR A  11
ARG A 281
SER A 174
GLY A 178
 CA  A1503 (-3.8A)
None
None
CA  A1503 (-2.6A)
None
 1.19A 3mg0N-2gjmA:
undetectable		 3mg0N-2gjmA:
14.83
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3OGW_A_IMNA597_1
(LACTOPEROXIDASE)		 2gjm LACTOPEROXIDASE
(Bubalus
bubalis) 		8 / 9 GLN A  91
HIS A  95
PHE A  99
GLU A 102
ARG A 239
GLU A 242
PHE A 366
GLN A 408
 HEM  A 605 (-3.4A)
SCN  A1502 ( 4.8A)
HEM  A 605 (-4.8A)
None
HEM  A 605 (-4.7A)
HEM  A 605 ( 2.2A)
None
HEM  A 605 ( 4.6A)
 0.50A 3ogwA-2gjmA:
65.8		 3ogwA-2gjmA:
99.66
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3PY4_A_TYLA598_1
(LACTOPEROXIDASE)		 2gjm LACTOPEROXIDASE
(Bubalus
bubalis) 		5 / 5 GLN A  91
HIS A  95
ARG A 239
GLU A 242
PHE A 366
 HEM  A 605 (-3.4A)
SCN  A1502 ( 4.8A)
HEM  A 605 (-4.7A)
HEM  A 605 ( 2.2A)
None
 0.37A 3py4A-2gjmA:
65.9		 3py4A-2gjmA:
99.66
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3QF1_A_PZEA6951_1
(LACTOPEROXIDASE)		 2gjm LACTOPEROXIDASE
(Bubalus
bubalis) 		3 / 3 HIS A  95
ARG A 239
GLU A 242
 SCN  A1502 ( 4.8A)
HEM  A 605 (-4.7A)
HEM  A 605 ( 2.2A)
 0.45A 3qf1A-2gjmA:
60.5		 3qf1A-2gjmA:
95.54
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3QL6_A_NIMA614_1
(LACTOPEROXIDASE)		 2gjm LACTOPEROXIDASE
(Bubalus
bubalis) 		7 / 7 GLN A  91
HIS A  95
GLU A 102
ARG A 239
GLU A 242
PHE A 366
PRO A 409
 HEM  A 605 (-3.4A)
SCN  A1502 ( 4.8A)
None
HEM  A 605 (-4.7A)
HEM  A 605 ( 2.2A)
None
None
 0.64A 3ql6A-2gjmA:
60.6		 3ql6A-2gjmA:
99.66
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3R4X_A_PZAA597_0
(LACTOPEROXIDASE)		 2gjm LACTOPEROXIDASE
(Bubalus
bubalis) 		5 / 5 GLN A  91
ASP A  94
HIS A  95
ARG A 239
GLU A 242
 HEM  A 605 (-3.4A)
HEM  A 605 (-2.0A)
SCN  A1502 ( 4.8A)
HEM  A 605 (-4.7A)
HEM  A 605 ( 2.2A)
 0.45A 3r4xA-2gjmA:
60.9		 3r4xA-2gjmA:
99.66
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3R4X_A_PZAA598_0
(LACTOPEROXIDASE)		 2gjm LACTOPEROXIDASE
(Bubalus
bubalis) 		5 / 5 PHE A 238
ARG A 239
GLU A 242
PHE A 366
PRO A 409
 None
HEM  A 605 (-4.7A)
HEM  A 605 ( 2.2A)
None
None
 0.71A 3r4xA-2gjmA:
60.9		 3r4xA-2gjmA:
99.66
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3R55_A_PZAA597_0
(LACTOPEROXIDASE)		 2gjm LACTOPEROXIDASE
(Bubalus
bubalis) 		5 / 5 GLN A  91
ASP A  94
HIS A  95
ARG A 239
GLU A 242
 HEM  A 605 (-3.4A)
HEM  A 605 (-2.0A)
SCN  A1502 ( 4.8A)
HEM  A 605 (-4.7A)
HEM  A 605 ( 2.2A)
 0.39A 3r55A-2gjmA:
61.1		 3r55A-2gjmA:
95.54
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3R55_A_PZAA598_0
(LACTOPEROXIDASE)		 2gjm LACTOPEROXIDASE
(Bubalus
bubalis) 		3 / 3 GLU A 242
PHE A 366
GLN A 408
 HEM  A 605 ( 2.2A)
None
HEM  A 605 ( 4.6A)
 0.38A 3r55A-2gjmA:
61.1		 3r55A-2gjmA:
95.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T3R_C_9PLC501_1
(CYTOCHROME P450 2A6)		 2gjm LACTOPEROXIDASE
(Bubalus
bubalis) 		5 / 9 PHE A 503
PHE A 293
PHE A 328
ILE A 506
PHE A 332
 None
None
None
None
HEM  A 605 (-4.4A)
 1.41A 3t3rC-2gjmA:
undetectable		 3t3rC-2gjmA:
20.23
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3TGY_A_ASCA800_0
(LACTOPEROXIDASE)		 2gjm LACTOPEROXIDASE
(Bubalus
bubalis) 		4 / 4 HIS A  95
ARG A 239
GLU A 242
PHE A 366
 SCN  A1502 ( 4.8A)
HEM  A 605 (-4.7A)
HEM  A 605 ( 2.2A)
None
 0.50A 3tgyA-2gjmA:
60.1		 3tgyA-2gjmA:
99.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C9N_A_CAMA1419_0
(CYTOCHROME P450)		 2gjm LACTOPEROXIDASE
(Bubalus
bubalis) 		4 / 8 THR A 248
LEU A  84
LEU A 384
GLY A 383
 None
 0.61A 4c9nA-2gjmA:
undetectable		 4c9nA-2gjmA:
20.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EJJ_B_NCTB501_1
(CYTOCHROME P450 2A6)		 2gjm LACTOPEROXIDASE
(Bubalus
bubalis) 		4 / 7 PHE A 503
VAL A 300
GLY A  90
PHE A 328
 None
None
HEM  A 605 (-3.4A)
None
 0.88A 4ejjB-2gjmA:
undetectable		 4ejjB-2gjmA:
20.23
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4GN6_A_TYLA621_1
(LACTOPEROXIDASE)		 2gjm LACTOPEROXIDASE
(Bubalus
bubalis) 		4 / 4 HIS A  95
ARG A 239
GLU A 242
PHE A 366
 SCN  A1502 ( 4.8A)
HEM  A 605 (-4.7A)
HEM  A 605 ( 2.2A)
None
 0.39A 4gn6A-2gjmA:
65.0		 4gn6A-2gjmA:
99.66
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4IG5_A_MMZA616_1
(LACTOPEROXIDASE)		 2gjm LACTOPEROXIDASE
(Bubalus
bubalis) 		5 / 5 GLN A  91
HIS A  95
ARG A 239
GLU A 242
LEU A 246
 HEM  A 605 (-3.4A)
SCN  A1502 ( 4.8A)
HEM  A 605 (-4.7A)
HEM  A 605 ( 2.2A)
None
 0.43A 4ig5A-2gjmA:
59.5		 4ig5A-2gjmA:
95.54
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4IG5_B_MMZB617_1
(LACTOPEROXIDASE)		 2gjm LACTOPEROXIDASE
(Bubalus
bubalis) 		5 / 5 GLN A  91
HIS A  95
ARG A 239
GLU A 242
LEU A 246
 HEM  A 605 (-3.4A)
SCN  A1502 ( 4.8A)
HEM  A 605 (-4.7A)
HEM  A 605 ( 2.2A)
None
 0.37A 4ig5B-2gjmA:
60.0		 4ig5B-2gjmA:
95.54
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4KSZ_A_CYSA620_0
(LACTOPEROXIDASE)		 2gjm LACTOPEROXIDASE
(Bubalus
bubalis) 		3 / 3 ARG A 239
GLU A 242
PHE A 366
 HEM  A 605 (-4.7A)
HEM  A 605 ( 2.2A)
None
 0.49A 4kszA-2gjmA:
65.0		 4kszA-2gjmA:
99.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L3G_F_ACTF401_0
(METHYLAMINE
DEHYDROGENASE HEAVY
CHAIN)		 2gjm LACTOPEROXIDASE
(Bubalus
bubalis) 		3 / 3 ARG A 345
LEU A 359
GLU A 358
 None
 0.76A 4l3gF-2gjmA:
undetectable		 4l3gF-2gjmA:
20.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L8F_D_MTXD301_1
(GAMMA-GLUTAMYL
HYDROLASE)		 2gjm LACTOPEROXIDASE
(Bubalus
bubalis) 		5 / 11 GLY A 195
GLY A 273
ALA A 280
LEU A 276
HIS A 257
 None
 1.11A 4l8fD-2gjmA:
undetectable		 4l8fD-2gjmA:
18.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OAD_A_CLMA205_0
(GNAT SUPERFAMILY
ACETYLTRANSFERASE
PA4794)		 2gjm LACTOPEROXIDASE
(Bubalus
bubalis) 		5 / 12 GLU A 274
TYR A   7
ARG A 188
ALA A 280
LEU A 284
 None
 1.13A 4oadA-2gjmA:
undetectable		 4oadA-2gjmA:
15.96
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4QYQ_A_3CJA607_1
(LACTOPEROXIDASE)		 2gjm LACTOPEROXIDASE
(Bubalus
bubalis) 		3 / 3 GLN A  91
HIS A  95
ARG A 239
 HEM  A 605 (-3.4A)
SCN  A1502 ( 4.8A)
HEM  A 605 (-4.7A)
 0.40A 4qyqA-2gjmA:
59.2		 4qyqA-2gjmA:
95.54
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4QYQ_B_3CJB607_1
(LACTOPEROXIDASE)		 2gjm LACTOPEROXIDASE
(Bubalus
bubalis) 		3 / 3 GLN A  91
HIS A  95
ARG A 239
 HEM  A 605 (-3.4A)
SCN  A1502 ( 4.8A)
HEM  A 605 (-4.7A)
 0.30A 4qyqB-2gjmA:
58.9		 4qyqB-2gjmA:
95.54
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4QYQ_C_3CJC607_1
(LACTOPEROXIDASE)		 2gjm LACTOPEROXIDASE
(Bubalus
bubalis) 		6 / 6 GLN A  91
ASP A  94
HIS A  95
ARG A 239
GLU A 242
ARG A 333
 HEM  A 605 (-3.4A)
HEM  A 605 (-2.0A)
SCN  A1502 ( 4.8A)
HEM  A 605 (-4.7A)
HEM  A 605 ( 2.2A)
HEM  A 605 (-2.8A)
 0.56A 4qyqC-2gjmA:
27.2		 4qyqC-2gjmA:
95.54
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4QYQ_D_3CJD607_1
(LACTOPEROXIDASE)		 2gjm LACTOPEROXIDASE
(Bubalus
bubalis) 		4 / 4 GLN A  91
HIS A  95
ARG A 239
GLU A 242
 HEM  A 605 (-3.4A)
SCN  A1502 ( 4.8A)
HEM  A 605 (-4.7A)
HEM  A 605 ( 2.2A)
 0.53A 4qyqD-2gjmA:
22.2		 4qyqD-2gjmA:
95.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WW7_A_ACTA303_0
(EKC/KEOPS COMPLEX
SUBUNIT BUD32)		 2gjm LACTOPEROXIDASE
(Bubalus
bubalis) 		4 / 4 LEU A 455
VAL A 454
GLU A 483
ARG A 437
 None
 1.49A 4ww7A-2gjmA:
0.0		 4ww7A-2gjmA:
19.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DQF_A_CZEA613_1
(SERUM ALBUMIN)		 2gjm LACTOPEROXIDASE
(Bubalus
bubalis) 		5 / 9 ALA A 280
LEU A 196
GLY A 195
LEU A 276
LEU A 264
 None
 1.16A 5dqfA-2gjmA:
undetectable		 5dqfA-2gjmA:
22.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DZK_S_BEZS801_0
(ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 2
BEZ-LEU-LEU)		 2gjm LACTOPEROXIDASE
(Bubalus
bubalis) 		4 / 6 PHE A 503
SER A 325
LEU A 498
LEU A 499
 None
 1.28A 5dzke-2gjmA:
undetectable
5dzks-2gjmA:
undetectable		 5dzke-2gjmA:
15.38
5dzks-2gjmA:
2.30
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5FF1_A_MMZA601_1
(LACTOPEROXIDASE)		 2gjm LACTOPEROXIDASE
(Bubalus
bubalis) 		5 / 5 GLN A  91
HIS A  95
ARG A 239
GLU A 242
LEU A 246
 HEM  A 605 (-3.4A)
SCN  A1502 ( 4.8A)
HEM  A 605 (-4.7A)
HEM  A 605 ( 2.2A)
None
 0.39A 5ff1A-2gjmA:
59.5		 5ff1A-2gjmA:
95.54
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5FF1_A_MMZA602_1
(LACTOPEROXIDASE)		 2gjm LACTOPEROXIDASE
(Bubalus
bubalis) 		5 / 5 GLN A  91
HIS A  95
ARG A 239
GLU A 242
LEU A 246
 HEM  A 605 (-3.4A)
SCN  A1502 ( 4.8A)
HEM  A 605 (-4.7A)
HEM  A 605 ( 2.2A)
None
 0.39A 5ff1A-2gjmA:
59.5		 5ff1A-2gjmA:
95.54
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5FF1_B_MMZB601_1
(LACTOPEROXIDASE)		 2gjm LACTOPEROXIDASE
(Bubalus
bubalis) 		5 / 5 GLN A  91
HIS A  95
ARG A 239
GLU A 242
LEU A 246
 HEM  A 605 (-3.4A)
SCN  A1502 ( 4.8A)
HEM  A 605 (-4.7A)
HEM  A 605 ( 2.2A)
None
 0.38A 5ff1B-2gjmA:
65.7		 5ff1B-2gjmA:
95.54
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5FF1_B_MMZB613_1
(LACTOPEROXIDASE)		 2gjm LACTOPEROXIDASE
(Bubalus
bubalis) 		5 / 5 GLN A  91
HIS A  95
ARG A 239
GLU A 242
LEU A 246
 HEM  A 605 (-3.4A)
SCN  A1502 ( 4.8A)
HEM  A 605 (-4.7A)
HEM  A 605 ( 2.2A)
None
 0.38A 5ff1B-2gjmA:
65.7		 5ff1B-2gjmA:
95.54
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5HPW_A_3CJA609_1
(LACTOPEROXIDASE)		 2gjm LACTOPEROXIDASE
(Bubalus
bubalis) 		5 / 5 GLN A  91
HIS A  95
ARG A 239
GLU A 242
ARG A 333
 HEM  A 605 (-3.4A)
SCN  A1502 ( 4.8A)
HEM  A 605 (-4.7A)
HEM  A 605 ( 2.2A)
HEM  A 605 (-2.8A)
 0.43A 5hpwA-2gjmA:
59.2		 5hpwA-2gjmA:
95.54
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5HPW_B_3CJB609_1
(LACTOPEROXIDASE)		 2gjm LACTOPEROXIDASE
(Bubalus
bubalis) 		4 / 4 GLN A  91
HIS A  95
ARG A 239
ARG A 333
 HEM  A 605 (-3.4A)
SCN  A1502 ( 4.8A)
HEM  A 605 (-4.7A)
HEM  A 605 (-2.8A)
 0.38A 5hpwB-2gjmA:
59.0		 5hpwB-2gjmA:
95.54
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5HPW_C_3CJC609_1
(LACTOPEROXIDASE)		 2gjm LACTOPEROXIDASE
(Bubalus
bubalis) 		6 / 6 GLN A  91
ASP A  94
HIS A  95
ARG A 239
GLU A 242
ARG A 333
 HEM  A 605 (-3.4A)
HEM  A 605 (-2.0A)
SCN  A1502 ( 4.8A)
HEM  A 605 (-4.7A)
HEM  A 605 ( 2.2A)
HEM  A 605 (-2.8A)
 0.56A 5hpwC-2gjmA:
27.2		 5hpwC-2gjmA:
95.54
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5HPW_D_3CJD609_1
(LACTOPEROXIDASE)		 2gjm LACTOPEROXIDASE
(Bubalus
bubalis) 		4 / 4 GLN A  91
HIS A  95
ARG A 239
GLU A 242
 HEM  A 605 (-3.4A)
SCN  A1502 ( 4.8A)
HEM  A 605 (-4.7A)
HEM  A 605 ( 2.2A)
 0.53A 5hpwD-2gjmA:
22.1		 5hpwD-2gjmA:
95.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JI0_A_9CRA501_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 2gjm LACTOPEROXIDASE
(Bubalus
bubalis) 		6 / 11 ILE A 478
LEU A 467
ARG A 426
LEU A 422
ALA A  61
LEU A 460
 None
 1.26A 5ji0A-2gjmA:
undetectable		 5ji0A-2gjmA:
17.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KKZ_O_ASCO1004_0
(CYTOCHROME B
UBIQUINOL-CYTOCHROME
C REDUCTASE
IRON-SULFUR SUBUNIT)		 2gjm LACTOPEROXIDASE
(Bubalus
bubalis) 		4 / 7 HIS A  95
ILE A  92
VAL A  93
TYR A 296
 SCN  A1502 ( 4.8A)
None
None
None
 1.24A 5kkzM-2gjmA:
undetectable
5kkzO-2gjmA:
undetectable		 5kkzM-2gjmA:
15.16
5kkzO-2gjmA:
22.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L5Z_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 2gjm LACTOPEROXIDASE
(Bubalus
bubalis) 		5 / 12 THR A 168
THR A  11
ARG A 281
SER A 174
GLY A 178
 CA  A1503 (-3.8A)
None
None
CA  A1503 (-2.6A)
None
 1.23A 5l5zV-2gjmA:
undetectable
5l5zb-2gjmA:
undetectable		 5l5zV-2gjmA:
18.62
5l5zb-2gjmA:
14.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L5Z_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 2gjm LACTOPEROXIDASE
(Bubalus
bubalis) 		5 / 12 THR A 168
THR A  11
ARG A 281
SER A 174
GLY A 178
 CA  A1503 (-3.8A)
None
None
CA  A1503 (-2.6A)
None
 1.23A 5l5zH-2gjmA:
undetectable
5l5zN-2gjmA:
undetectable		 5l5zH-2gjmA:
18.62
5l5zN-2gjmA:
14.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LF3_B_BO2B305_1
(PROTEASOME SUBUNIT
BETA TYPE-6)		 2gjm LACTOPEROXIDASE
(Bubalus
bubalis) 		5 / 12 THR A 168
THR A  11
ARG A 281
SER A 174
GLY A 178
 CA  A1503 (-3.8A)
None
None
CA  A1503 (-2.6A)
None
 1.22A 5lf3b-2gjmA:
undetectable		 5lf3b-2gjmA:
17.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LF3_N_BO2N304_1
(PROTEASOME SUBUNIT
BETA TYPE-6)		 2gjm LACTOPEROXIDASE
(Bubalus
bubalis) 		5 / 12 THR A 168
THR A  11
ARG A 281
SER A 174
GLY A 178
 CA  A1503 (-3.8A)
None
None
CA  A1503 (-2.6A)
None
 1.23A 5lf3N-2gjmA:
undetectable		 5lf3N-2gjmA:
17.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LG3_I_Z80I401_1
(GAMMA-AMINOBUTYRIC-A
CID RECEPTOR SUBUNIT
BETA-1)		 2gjm LACTOPEROXIDASE
(Bubalus
bubalis) 		4 / 9 VAL A 343
ASN A 367
ASP A 374
ILE A 244
 None
 0.96A 5lg3I-2gjmA:
undetectable		 5lg3I-2gjmA:
21.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NNW_D_GCSD302_1
(25 KDA PROTEIN
ELICITOR)		 2gjm LACTOPEROXIDASE
(Bubalus
bubalis) 		4 / 7 GLY A 335
HIS A 336
HIS A  95
ASP A  94
 HEM  A 605 (-3.4A)
HEM  A 605 (-3.3A)
SCN  A1502 ( 4.8A)
HEM  A 605 (-2.0A)
 1.07A 5nnwD-2gjmA:
undetectable		 5nnwD-2gjmA:
11.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z12_B_9CRB501_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 2gjm LACTOPEROXIDASE
(Bubalus
bubalis) 		6 / 12 ILE A 478
LEU A 467
ARG A 426
LEU A 422
ALA A  61
LEU A 460
 None
 1.27A 5z12B-2gjmA:
undetectable		 5z12B-2gjmA:
10.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6I0Y_A_TRPA3001_0
(23S RIBOSOMAL RNA
TRYPTOPHANASE OPERON
LEADER PEPTIDE)		 2gjm LACTOPEROXIDASE
(Bubalus
bubalis) 		3 / 3 TRP A 369
ILE A 371
ASP A 374
 NAG  A 585 (-3.9A)
None
None
 0.82A 6i0y7-2gjmA:
undetectable		 6i0y7-2gjmA:
3.89