SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2gjn'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P91_B_SAMB2401_0
(RIBOSOMAL RNA LARGE
SUBUNIT
METHYLTRANSFERASE A)		 2gjn HYPOTHETICAL PROTEIN
PA1024
(Pseudomonas
aeruginosa) 		5 / 12 LEU A 187
GLY A  21
GLY A 201
ILE A  18
PRO A 174
 None
FMN  A1904 (-4.0A)
FMN  A1904 (-3.3A)
None
None
 0.97A 1p91B-2gjnA:
undetectable		 1p91B-2gjnA:
21.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PK7_B_ADNB1246_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 2gjn HYPOTHETICAL PROTEIN
PA1024
(Pseudomonas
aeruginosa) 		5 / 8 ARG A 172
GLY A 138
VAL A 139
GLU A 135
ILE A 111
 None
 1.49A 1pk7B-2gjnA:
undetectable		 1pk7B-2gjnA:
24.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PW7_B_RABB646_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 2gjn HYPOTHETICAL PROTEIN
PA1024
(Pseudomonas
aeruginosa) 		5 / 9 ARG A 172
GLY A 138
VAL A 139
GLU A 135
ILE A 111
 None
 1.41A 1pw7B-2gjnA:
undetectable		 1pw7B-2gjnA:
24.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1VHW_A_ADNA252_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 2gjn HYPOTHETICAL PROTEIN
PA1024
(Pseudomonas
aeruginosa) 		5 / 11 ARG A 172
GLY A 138
VAL A 139
GLU A 135
ILE A 111
 None
 1.41A 1vhwA-2gjnA:
undetectable
1vhwD-2gjnA:
undetectable		 1vhwA-2gjnA:
22.26
1vhwD-2gjnA:
22.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1VHW_C_ADNC252_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 2gjn HYPOTHETICAL PROTEIN
PA1024
(Pseudomonas
aeruginosa) 		5 / 11 ARG A 172
GLY A 138
VAL A 139
GLU A 135
ILE A 111
 None
 1.42A 1vhwC-2gjnA:
undetectable
1vhwE-2gjnA:
undetectable		 1vhwC-2gjnA:
22.26
1vhwE-2gjnA:
22.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1VHW_D_ADND252_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 2gjn HYPOTHETICAL PROTEIN
PA1024
(Pseudomonas
aeruginosa) 		5 / 11 ARG A 172
GLY A 138
VAL A 139
GLU A 135
ILE A 111
 None
 1.41A 1vhwA-2gjnA:
undetectable
1vhwD-2gjnA:
undetectable		 1vhwA-2gjnA:
22.26
1vhwD-2gjnA:
22.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1VHW_E_ADNE252_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 2gjn HYPOTHETICAL PROTEIN
PA1024
(Pseudomonas
aeruginosa) 		5 / 11 ARG A 172
GLY A 138
VAL A 139
GLU A 135
ILE A 111
 None
 1.41A 1vhwC-2gjnA:
undetectable
1vhwE-2gjnA:
undetectable		 1vhwC-2gjnA:
22.26
1vhwE-2gjnA:
22.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BL9_A_CP6A1240_1
(DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE)		 2gjn HYPOTHETICAL PROTEIN
PA1024
(Pseudomonas
aeruginosa) 		5 / 12 ILE A 309
ALA A 313
LEU A 191
ILE A 176
ILE A  18
 None
 1.17A 2bl9A-2gjnA:
undetectable		 2bl9A-2gjnA:
16.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IVU_A_ZD6A3015_1
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE RECEPTOR RET
PRECURSOR)		 2gjn HYPOTHETICAL PROTEIN
PA1024
(Pseudomonas
aeruginosa) 		3 / 3 ALA A 103
GLY A 151
SER A 178
 FMN  A1904 (-3.1A)
NIS  A 500 (-2.8A)
FMN  A1904 (-3.2A)
 0.38A 2ivuA-2gjnA:
undetectable		 2ivuA-2gjnA:
21.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QD5_B_CHDB1103_0
(FERROCHELATASE)		 2gjn HYPOTHETICAL PROTEIN
PA1024
(Pseudomonas
aeruginosa) 		4 / 8 ARG A 172
PRO A 107
VAL A 139
GLY A 138
 None
 0.95A 2qd5B-2gjnA:
undetectable		 2qd5B-2gjnA:
19.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WD9_A_IBPA1570_1
(ACYL-COENZYME A
SYNTHETASE ACSM2A,
MITOCHONDRIAL)		 2gjn HYPOTHETICAL PROTEIN
PA1024
(Pseudomonas
aeruginosa) 		4 / 7 ILE A 296
LEU A 295
GLY A 180
GLY A 290
 None
None
FMN  A1904 (-3.7A)
FMN  A1904 ( 4.1A)
 0.76A 2wd9A-2gjnA:
2.6		 2wd9A-2gjnA:
19.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WD9_B_IBPB1570_1
(ACYL-COENZYME A
SYNTHETASE ACSM2A,
MITOCHONDRIAL)		 2gjn HYPOTHETICAL PROTEIN
PA1024
(Pseudomonas
aeruginosa) 		4 / 8 ILE A 296
LEU A 295
GLY A 180
GLY A 290
 None
None
FMN  A1904 (-3.7A)
FMN  A1904 ( 4.1A)
 0.77A 2wd9B-2gjnA:
2.5		 2wd9B-2gjnA:
19.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ADX_B_IMNB3_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 2gjn HYPOTHETICAL PROTEIN
PA1024
(Pseudomonas
aeruginosa) 		5 / 12 GLY A 273
SER A 288
ALA A 289
VAL A 250
ILE A 246
 None
NIS  A 500 ( 3.2A)
None
None
None
 0.92A 3adxB-2gjnA:
undetectable		 3adxB-2gjnA:
22.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EKP_B_478B200_1
(PROTEASE)		 2gjn HYPOTHETICAL PROTEIN
PA1024
(Pseudomonas
aeruginosa) 		5 / 8 GLY A  21
VAL A  99
GLY A  40
ILE A  18
ILE A 122
 FMN  A1904 (-4.0A)
None
None
None
None
 1.03A 3ekpA-2gjnA:
undetectable		 3ekpA-2gjnA:
13.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IJD_A_C2FA314_0
(UNCHARACTERIZED
PROTEIN)		 2gjn HYPOTHETICAL PROTEIN
PA1024
(Pseudomonas
aeruginosa) 		5 / 12 THR A   6
LEU A 191
VAL A 317
LEU A 187
ILE A 309
 None
 1.11A 3ijdA-2gjnA:
8.2		 3ijdA-2gjnA:
19.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MBG_B_ACTB600_0
(FAD-LINKED
SULFHYDRYL OXIDASE
ALR)		 2gjn HYPOTHETICAL PROTEIN
PA1024
(Pseudomonas
aeruginosa) 		4 / 5 ARG A 307
ALA A  38
GLU A  15
HIS A  16
 None
 1.06A 3mbgB-2gjnA:
0.0
3mbgC-2gjnA:
0.0		 3mbgB-2gjnA:
17.07
3mbgC-2gjnA:
17.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MBG_C_ACTC600_0
(FAD-LINKED
SULFHYDRYL OXIDASE
ALR)		 2gjn HYPOTHETICAL PROTEIN
PA1024
(Pseudomonas
aeruginosa) 		4 / 5 GLU A  15
HIS A  16
ARG A 307
ALA A  38
 None
 1.05A 3mbgB-2gjnA:
0.0
3mbgC-2gjnA:
0.0		 3mbgB-2gjnA:
17.07
3mbgC-2gjnA:
17.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PGH_C_FLPC701_1
(CYCLOOXYGENASE-2)		 2gjn HYPOTHETICAL PROTEIN
PA1024
(Pseudomonas
aeruginosa) 		5 / 12 VAL A 216
VAL A 241
GLY A 290
ALA A 289
LEU A 205
 None
None
FMN  A1904 ( 4.1A)
None
FMN  A1904 ( 4.8A)
 0.95A 3pghC-2gjnA:
undetectable		 3pghC-2gjnA:
19.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HOJ_A_ACTA303_0
(REGF PROTEIN)		 2gjn HYPOTHETICAL PROTEIN
PA1024
(Pseudomonas
aeruginosa) 		4 / 5 VAL A  26
ARG A  28
MET A  31
GLU A  30
 None
 0.94A 4hojA-2gjnA:
undetectable		 4hojA-2gjnA:
20.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KIC_A_SAMA401_0
(METHYLTRANSFERASE
MPPJ)		 2gjn HYPOTHETICAL PROTEIN
PA1024
(Pseudomonas
aeruginosa) 		6 / 12 GLY A 180
GLY A 146
ARG A 240
ILE A 198
ALA A 177
ALA A 182
 FMN  A1904 (-3.7A)
None
None
None
None
None
 1.41A 4kicA-2gjnA:
undetectable		 4kicA-2gjnA:
21.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KIC_B_SAMB401_0
(METHYLTRANSFERASE
MPPJ)		 2gjn HYPOTHETICAL PROTEIN
PA1024
(Pseudomonas
aeruginosa) 		5 / 12 GLY A 180
GLY A 146
ILE A 198
ALA A 177
ALA A 182
 FMN  A1904 (-3.7A)
None
None
None
None
 1.12A 4kicB-2gjnA:
undetectable		 4kicB-2gjnA:
21.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UUU_A_SAMA1546_0
(CYSTATHIONINE
BETA-SYNTHASE)		 2gjn HYPOTHETICAL PROTEIN
PA1024
(Pseudomonas
aeruginosa) 		5 / 11 LEU A 187
GLN A 312
ALA A 313
ILE A 296
ASP A 298
 None
 1.06A 4uuuA-2gjnA:
undetectable
4uuuB-2gjnA:
undetectable		 4uuuA-2gjnA:
17.82
4uuuB-2gjnA:
17.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X20_D_LOCD502_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		 2gjn HYPOTHETICAL PROTEIN
PA1024
(Pseudomonas
aeruginosa) 		3 / 3 SER A 227
ALA A 242
VAL A 241
 None
 0.58A 4x20C-2gjnA:
undetectable		 4x20C-2gjnA:
22.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5E72_A_SAMA400_0
(N2,
N2-DIMETHYLGUANOSINE
TRNA
METHYLTRANSFERASE)		 2gjn HYPOTHETICAL PROTEIN
PA1024
(Pseudomonas
aeruginosa) 		5 / 12 ILE A 296
PHE A 181
ILE A 309
ALA A 177
ASP A 183
 None
 0.97A 5e72A-2gjnA:
undetectable		 5e72A-2gjnA:
23.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JCN_A_ASCA502_0
(OS09G0567300 PROTEIN)		 2gjn HYPOTHETICAL PROTEIN
PA1024
(Pseudomonas
aeruginosa) 		4 / 5 GLU A 155
PRO A 153
ARG A 233
PHE A 147
 None
 1.17A 5jcnA-2gjnA:
0.0		 5jcnA-2gjnA:
24.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JCN_B_ASCB502_0
(OS09G0567300 PROTEIN)		 2gjn HYPOTHETICAL PROTEIN
PA1024
(Pseudomonas
aeruginosa) 		4 / 6 GLU A 155
PRO A 153
ARG A 233
PHE A 147
 None
 1.15A 5jcnB-2gjnA:
undetectable		 5jcnB-2gjnA:
24.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KPR_A_PAUA404_0
(PANTOTHENATE KINASE
3)		 2gjn HYPOTHETICAL PROTEIN
PA1024
(Pseudomonas
aeruginosa) 		4 / 5 GLU A 101
GLY A 201
SER A 178
GLY A 179
 FMN  A1904 ( 4.7A)
FMN  A1904 (-3.3A)
FMN  A1904 (-3.2A)
FMN  A1904 (-3.4A)
 1.03A 5kprA-2gjnA:
undetectable		 5kprA-2gjnA:
23.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EBP_A_DAHA123_0
(RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE,
BETA SUBUNIT)		 2gjn HYPOTHETICAL PROTEIN
PA1024
(Pseudomonas
aeruginosa) 		5 / 9 LEU A  41
GLY A 201
PHE A 204
PHE A   8
ILE A 176
 None
FMN  A1904 (-3.3A)
None
None
None
 1.35A 6ebpA-2gjnA:
undetectable		 6ebpA-2gjnA:
12.50