SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2gjv'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIN_W_CHDW1060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 1)		 2gjv PUTATIVE CYTOPLASMIC
PROTEIN
(Salmonella
enterica) 		4 / 6 ILE A   7
ARG A  67
MET A 124
LEU A 103
 None
 1.02A 2einN-2gjvA:
undetectable
2einW-2gjvA:
undetectable		 2einN-2gjvA:
16.31
2einW-2gjvA:
16.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JW3_A_TOPA208_1
(DIHYDROFOLATE
REDUCTASE)		 2gjv PUTATIVE CYTOPLASMIC
PROTEIN
(Salmonella
enterica) 		5 / 10 ALA A  70
LEU A 103
VAL A  10
ILE A  66
ILE A   7
 None
 1.14A 3jw3A-2gjvA:
undetectable		 3jw3A-2gjvA:
22.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OEZ_A_STIA601_2
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE SRC)		 2gjv PUTATIVE CYTOPLASMIC
PROTEIN
(Salmonella
enterica) 		4 / 5 VAL A   6
ILE A  25
MET A  21
ARG A  67
 None
 1.41A 3oezA-2gjvA:
2.7		 3oezA-2gjvA:
18.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PYY_B_STIB4_2
(V-ABL ABELSON MURINE
LEUKEMIA VIRAL
ONCOGENE HOMOLOG 1
ISOFORM B VARIANT)		 2gjv PUTATIVE CYTOPLASMIC
PROTEIN
(Salmonella
enterica) 		4 / 5 VAL A   6
ILE A  25
MET A  21
ARG A  67
 None
 1.46A 3pyyB-2gjvA:
2.4		 3pyyB-2gjvA:
22.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P68_A_MTXA201_1
(DIHYDROFOLATE
REDUCTASE)		 2gjv PUTATIVE CYTOPLASMIC
PROTEIN
(Salmonella
enterica) 		5 / 11 ILE A  44
SER A  49
ILE A  66
ILE A   7
THR A  71
 None
 1.42A 4p68A-2gjvA:
undetectable		 4p68A-2gjvA:
23.35