SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2gjz'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1DSD_C_DVAC2_0 (ACTINOMYCIN D)	2gjz	CATALYTIC ELIMINATION ANTIBODY 13G5 HEAVY CHAIN (Mus musculus)	4 / 4	THR H 116 PRO H 118 THR H 117 PRO H 149	None	1.35A	1dsdC-2gjzH: undetectable	1dsdC-2gjzH: 8.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1DSD_C_DVAC2_0 (ACTINOMYCIN D)	2gjz	CATALYTIC ELIMINATION ANTIBODY 13G5 HEAVY CHAIN (Mus musculus)	4 / 4	THR H 117 PRO H 149 THR H 116 PRO H 118	None	1.29A	1dsdC-2gjzH: undetectable	1dsdC-2gjzH: 8.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1DSD_C_DVAC8_0 (ACTINOMYCIN D)	2gjz	CATALYTIC ELIMINATION ANTIBODY 13G5 HEAVY CHAIN (Mus musculus)	4 / 4	THR H 116 PRO H 118 THR H 117 PRO H 149	None	1.35A	1dsdC-2gjzH: undetectable	1dsdC-2gjzH: 8.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1DSD_C_DVAC8_0 (ACTINOMYCIN D)	2gjz	CATALYTIC ELIMINATION ANTIBODY 13G5 HEAVY CHAIN (Mus musculus)	4 / 4	THR H 117 PRO H 149 THR H 116 PRO H 118	None	1.29A	1dsdC-2gjzH: undetectable	1dsdC-2gjzH: 8.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1LQU_B_ACTB1424_0 (FPRA)	2gjz	CATALYTIC ELIMINATION ANTIBODY 13G5 HEAVY CHAIN (Mus musculus)	4 / 4	ALA H 88 ARG H 38 GLN H 39 GLU H 46	None	1.49A	1lquB-2gjzH: undetectable	1lquB-2gjzH: 17.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4EM2_A_SALA501_1 (UNCHARACTERIZED HTH-TYPE TRANSCRIPTIONAL REGULATOR SAR2349)	2gjz	CATALYTIC ELIMINATION ANTIBODY 13G5 HEAVY CHAIN (Mus musculus)	4 / 5	TYR H 90 LEU H 80 LEU H 82 ARG H 66	None	1.21A	4em2A-2gjzH: undetectable	4em2A-2gjzH: 16.67
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4M93_B_ACTB305_0 (S25-26 FAB (IGG1K) HEAVY CHAIN)	2gjz	CATALYTIC ELIMINATION ANTIBODY 13G5 HEAVY CHAIN (Mus musculus)	4 / 4	SER H 19 THR H 21 PHE H 79 LYS H 81	None	0.90A	4m93B-2gjzH: 24.6	4m93B-2gjzH: 78.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5XIW_D_LOCD503_1 (TUBULIN ALPHA-1B CHAIN TUBULIN BETA CHAIN)	2gjz	CATALYTIC ELIMINATION ANTIBODY 13G5 HEAVY CHAIN (Mus musculus)	3 / 3	SER H 216 ALA H 211 VAL H 210	None	0.54A	5xiwC-2gjzH: undetectable	5xiwC-2gjzH: 14.93

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1DSD_C_DVAC2_0","ACTINOMYCIN D","2gjz","CATALYTIC ELIMINATION ANTIBODY 13G5 HEAVY CHAIN","Mus musculus",4,"THR H 116;PRO H 118;THR H 117;PRO H 149","None","1.35A","1dsdC-2gjzH:undetectable","1dsdC-2gjzH:8.20"],["1DSD_C_DVAC2_0","ACTINOMYCIN D","2gjz","CATALYTIC ELIMINATION ANTIBODY 13G5 HEAVY CHAIN","Mus musculus",4,"THR H 117;PRO H 149;THR H 116;PRO H 118","None","1.29A","1dsdC-2gjzH:undetectable","1dsdC-2gjzH:8.20"],["1DSD_C_DVAC8_0","ACTINOMYCIN D","2gjz","CATALYTIC ELIMINATION ANTIBODY 13G5 HEAVY CHAIN","Mus musculus",4,"THR H 116;PRO H 118;THR H 117;PRO H 149","None","1.35A","1dsdC-2gjzH:undetectable","1dsdC-2gjzH:8.20"],["1DSD_C_DVAC8_0","ACTINOMYCIN D","2gjz","CATALYTIC ELIMINATION ANTIBODY 13G5 HEAVY CHAIN","Mus musculus",4,"THR H 117;PRO H 149;THR H 116;PRO H 118","None","1.29A","1dsdC-2gjzH:undetectable","1dsdC-2gjzH:8.20"],["1LQU_B_ACTB1424_0","FPRA","2gjz","CATALYTIC ELIMINATION ANTIBODY 13G5 HEAVY CHAIN","Mus musculus",4,"ALA H  88;ARG H  38;GLN H  39;GLU H  46","None","1.49A","1lquB-2gjzH:undetectable","1lquB-2gjzH:17.23"],["4EM2_A_SALA501_1","UNCHARACTERIZED HTH-TYPE TRANSCRIPTIONAL REGULATOR SAR2349","2gjz","CATALYTIC ELIMINATION ANTIBODY 13G5 HEAVY CHAIN","Mus musculus",4,"TYR H  90;LEU H  80;LEU H  82;ARG H  66","None","1.21A","4em2A-2gjzH:undetectable","4em2A-2gjzH:16.67"],["4M93_B_ACTB305_0","S25-26 FAB (IGG1K) HEAVY CHAIN","2gjz","CATALYTIC ELIMINATION ANTIBODY 13G5 HEAVY CHAIN","Mus musculus",4,"SER H  19;THR H  21;PHE H  79;LYS H  81","None","0.90A","4m93B-2gjzH:24.6","4m93B-2gjzH:78.32"],["5XIW_D_LOCD503_1","TUBULIN ALPHA-1B CHAIN;TUBULIN BETA CHAIN","2gjz","CATALYTIC ELIMINATION ANTIBODY 13G5 HEAVY CHAIN","Mus musculus",3,"SER H 216;ALA H 211;VAL H 210","None","0.54A","5xiwC-2gjzH:undetectable","5xiwC-2gjzH:14.93"]]