SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2glf'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1D4F_D_ADND604_2
(S-ADENOSYLHOMOCYSTEI
NE HYDROLASE)		 2glf PROBABLE M18-FAMILY
AMINOPEPTIDASE 1
(Thermotoga
maritima) 		4 / 5 THR A 288
GLU A  35
THR A  38
HIS A  94
 None
None
None
MN  A5001 (-3.6A)
 1.42A 1d4fD-2glfA:
undetectable		 1d4fD-2glfA:
23.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E7C_A_HLTA4001_1
(SERUM ALBUMIN)		 2glf PROBABLE M18-FAMILY
AMINOPEPTIDASE 1
(Thermotoga
maritima) 		4 / 5 ARG A  71
LYS A  73
ALA A  74
GLY A 289
 None
 0.99A 1e7cA-2glfA:
undetectable		 1e7cA-2glfA:
23.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1K2R_B_H4BB2760_1
(NITRIC-OXIDE
SYNTHASE)		 2glf PROBABLE M18-FAMILY
AMINOPEPTIDASE 1
(Thermotoga
maritima) 		4 / 7 PHE A  21
GLU A  17
ARG A 261
VAL A 443
 None
 1.25A 1k2rA-2glfA:
undetectable
1k2rB-2glfA:
undetectable		 1k2rA-2glfA:
20.95
1k2rB-2glfA:
20.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1K2S_B_H4BB2760_1
(NITRIC-OXIDE
SYNTHASE)		 2glf PROBABLE M18-FAMILY
AMINOPEPTIDASE 1
(Thermotoga
maritima) 		4 / 6 PHE A  21
GLU A  17
ARG A 261
VAL A 443
 None
 1.26A 1k2sA-2glfA:
undetectable
1k2sB-2glfA:
undetectable		 1k2sA-2glfA:
20.95
1k2sB-2glfA:
20.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1K2U_B_H4BB2760_1
(NITRIC-OXIDE
SYNTHASE)		 2glf PROBABLE M18-FAMILY
AMINOPEPTIDASE 1
(Thermotoga
maritima) 		4 / 6 PHE A  21
GLU A  17
ARG A 261
VAL A 443
 None
 1.24A 1k2uA-2glfA:
undetectable
1k2uB-2glfA:
undetectable		 1k2uA-2glfA:
20.95
1k2uB-2glfA:
20.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LZX_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE)		 2glf PROBABLE M18-FAMILY
AMINOPEPTIDASE 1
(Thermotoga
maritima) 		4 / 7 ARG A 261
VAL A 443
PHE A  21
GLU A  17
 None
 1.25A 1lzxA-2glfA:
undetectable
1lzxB-2glfA:
undetectable		 1lzxA-2glfA:
20.95
1lzxB-2glfA:
20.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LZX_B_H4BB1760_1
(NITRIC-OXIDE
SYNTHASE)		 2glf PROBABLE M18-FAMILY
AMINOPEPTIDASE 1
(Thermotoga
maritima) 		4 / 7 PHE A  21
GLU A  17
ARG A 261
VAL A 443
 None
 1.26A 1lzxA-2glfA:
undetectable
1lzxB-2glfA:
undetectable		 1lzxA-2glfA:
20.95
1lzxB-2glfA:
20.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LZZ_B_H4BB1760_1
(NITRIC-OXIDE
SYNTHASE)		 2glf PROBABLE M18-FAMILY
AMINOPEPTIDASE 1
(Thermotoga
maritima) 		4 / 7 PHE A  21
GLU A  17
ARG A 261
VAL A 443
 None
 1.24A 1lzzA-2glfA:
undetectable
1lzzB-2glfA:
undetectable		 1lzzA-2glfA:
20.95
1lzzB-2glfA:
20.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MMV_B_H4BB2760_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 2glf PROBABLE M18-FAMILY
AMINOPEPTIDASE 1
(Thermotoga
maritima) 		4 / 7 PHE A  21
GLU A  17
ARG A 261
VAL A 443
 None
 1.26A 1mmvA-2glfA:
undetectable
1mmvB-2glfA:
undetectable		 1mmvA-2glfA:
20.95
1mmvB-2glfA:
20.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MMW_A_H4BA1760_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 2glf PROBABLE M18-FAMILY
AMINOPEPTIDASE 1
(Thermotoga
maritima) 		4 / 7 ARG A 261
VAL A 443
PHE A  21
GLU A  17
 None
 1.25A 1mmwA-2glfA:
undetectable
1mmwB-2glfA:
undetectable		 1mmwA-2glfA:
20.95
1mmwB-2glfA:
20.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MMW_B_H4BB2760_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 2glf PROBABLE M18-FAMILY
AMINOPEPTIDASE 1
(Thermotoga
maritima) 		4 / 7 PHE A  21
GLU A  17
ARG A 261
VAL A 443
 None
 1.24A 1mmwA-2glfA:
undetectable
1mmwB-2glfA:
undetectable		 1mmwA-2glfA:
20.95
1mmwB-2glfA:
20.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MX1_E_THAE5_2
(LIVER
CARBOXYLESTERASE I)		 2glf PROBABLE M18-FAMILY
AMINOPEPTIDASE 1
(Thermotoga
maritima) 		3 / 3 PHE A  51
LEU A 264
LEU A 260
 None
 0.52A 1mx1E-2glfA:
2.8		 1mx1E-2glfA:
21.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P6H_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 2glf PROBABLE M18-FAMILY
AMINOPEPTIDASE 1
(Thermotoga
maritima) 		4 / 6 ARG A 261
VAL A 443
PHE A  21
GLU A  17
 None
 1.24A 1p6hA-2glfA:
undetectable
1p6hB-2glfA:
undetectable		 1p6hA-2glfA:
20.87
1p6hB-2glfA:
20.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P6H_B_H4BB761_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 2glf PROBABLE M18-FAMILY
AMINOPEPTIDASE 1
(Thermotoga
maritima) 		4 / 7 PHE A  21
GLU A  17
ARG A 261
VAL A 443
 None
 1.25A 1p6hA-2glfA:
undetectable
1p6hB-2glfA:
undetectable		 1p6hA-2glfA:
20.87
1p6hB-2glfA:
20.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P6I_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 2glf PROBABLE M18-FAMILY
AMINOPEPTIDASE 1
(Thermotoga
maritima) 		4 / 7 ARG A 261
VAL A 443
PHE A  21
GLU A  17
 None
 1.24A 1p6iA-2glfA:
0.0
1p6iB-2glfA:
undetectable		 1p6iA-2glfA:
20.87
1p6iB-2glfA:
20.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P6K_B_H4BB761_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 2glf PROBABLE M18-FAMILY
AMINOPEPTIDASE 1
(Thermotoga
maritima) 		4 / 7 PHE A  21
GLU A  17
ARG A 261
VAL A 443
 None
 1.23A 1p6kA-2glfA:
0.0
1p6kB-2glfA:
undetectable		 1p6kA-2glfA:
20.87
1p6kB-2glfA:
20.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PK7_B_ADNB1246_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 2glf PROBABLE M18-FAMILY
AMINOPEPTIDASE 1
(Thermotoga
maritima) 		5 / 8 GLY A 246
VAL A 238
GLU A 237
GLU A  19
ILE A 432
 None
 1.18A 1pk7B-2glfA:
5.7		 1pk7B-2glfA:
21.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PK9_C_2FAC308_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 2glf PROBABLE M18-FAMILY
AMINOPEPTIDASE 1
(Thermotoga
maritima) 		5 / 11 GLY A 246
VAL A 238
GLU A 237
GLU A  19
ILE A 432
 None
 1.07A 1pk9C-2glfA:
6.5		 1pk9C-2glfA:
21.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PW7_B_RABB646_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 2glf PROBABLE M18-FAMILY
AMINOPEPTIDASE 1
(Thermotoga
maritima) 		5 / 9 GLY A 246
VAL A 238
GLU A 237
GLU A  19
ILE A 432
 None
 1.10A 1pw7B-2glfA:
4.0		 1pw7B-2glfA:
22.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RG7_A_MTXA161_1
(DIHYDROFOLATE
REDUCTASE)		 2glf PROBABLE M18-FAMILY
AMINOPEPTIDASE 1
(Thermotoga
maritima) 		5 / 12 ALA A 370
LEU A 355
SER A 326
ILE A 325
LEU A 448
 None
 1.11A 1rg7A-2glfA:
undetectable		 1rg7A-2glfA:
15.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RS6_B_H4BB761_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 2glf PROBABLE M18-FAMILY
AMINOPEPTIDASE 1
(Thermotoga
maritima) 		4 / 8 PHE A  21
GLU A  17
ARG A 261
VAL A 443
 None
 1.29A 1rs6A-2glfA:
undetectable
1rs6B-2glfA:
undetectable		 1rs6A-2glfA:
20.87
1rs6B-2glfA:
20.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1VHW_A_ADNA252_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 2glf PROBABLE M18-FAMILY
AMINOPEPTIDASE 1
(Thermotoga
maritima) 		5 / 11 GLY A 246
VAL A 238
GLU A 237
GLU A  19
ILE A 432
 None
 1.09A 1vhwA-2glfA:
6.3
1vhwD-2glfA:
6.1		 1vhwA-2glfA:
22.25
1vhwD-2glfA:
22.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1VHW_C_ADNC252_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 2glf PROBABLE M18-FAMILY
AMINOPEPTIDASE 1
(Thermotoga
maritima) 		5 / 11 GLY A 246
VAL A 238
GLU A 237
GLU A  19
ILE A 432
 None
 1.08A 1vhwC-2glfA:
6.1
1vhwE-2glfA:
6.4		 1vhwC-2glfA:
22.25
1vhwE-2glfA:
22.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1VHW_D_ADND252_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 2glf PROBABLE M18-FAMILY
AMINOPEPTIDASE 1
(Thermotoga
maritima) 		5 / 11 GLY A 246
VAL A 238
GLU A 237
GLU A  19
ILE A 432
 None
 1.09A 1vhwA-2glfA:
6.4
1vhwD-2glfA:
6.1		 1vhwA-2glfA:
22.25
1vhwD-2glfA:
22.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1VHW_E_ADNE252_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 2glf PROBABLE M18-FAMILY
AMINOPEPTIDASE 1
(Thermotoga
maritima) 		5 / 11 GLY A 246
VAL A 238
GLU A 237
GLU A  19
ILE A 432
 None
 1.09A 1vhwC-2glfA:
6.1
1vhwE-2glfA:
6.4		 1vhwC-2glfA:
22.25
1vhwE-2glfA:
22.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZVL_A_H4BA900_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 2glf PROBABLE M18-FAMILY
AMINOPEPTIDASE 1
(Thermotoga
maritima) 		4 / 7 ARG A 261
VAL A 443
PHE A  21
GLU A  17
 None
 1.24A 1zvlA-2glfA:
undetectable
1zvlB-2glfA:
undetectable		 1zvlA-2glfA:
20.96
1zvlB-2glfA:
20.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZZQ_B_H4BB761_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 2glf PROBABLE M18-FAMILY
AMINOPEPTIDASE 1
(Thermotoga
maritima) 		4 / 7 PHE A  21
GLU A  17
ARG A 261
VAL A 443
 None
 1.26A 1zzqA-2glfA:
undetectable
1zzqB-2glfA:
undetectable		 1zzqA-2glfA:
20.91
1zzqB-2glfA:
20.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DCF_A_ACAA501_1
(6-AMINOHEXANOATE-DIM
ER HYDROLASE)		 2glf PROBABLE M18-FAMILY
AMINOPEPTIDASE 1
(Thermotoga
maritima) 		4 / 6 ALA A 247
TYR A  25
ILE A 432
ILE A 245
 None
 1.15A 2dcfA-2glfA:
undetectable		 2dcfA-2glfA:
23.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2G6H_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 2glf PROBABLE M18-FAMILY
AMINOPEPTIDASE 1
(Thermotoga
maritima) 		4 / 8 ARG A 261
VAL A 443
PHE A  21
GLU A  17
 None
 1.26A 2g6hA-2glfA:
undetectable
2g6hB-2glfA:
undetectable		 2g6hA-2glfA:
20.91
2g6hB-2glfA:
20.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2G6H_B_H4BB761_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 2glf PROBABLE M18-FAMILY
AMINOPEPTIDASE 1
(Thermotoga
maritima) 		4 / 6 PHE A  21
GLU A  17
ARG A 261
VAL A 443
 None
 1.25A 2g6hA-2glfA:
undetectable
2g6hB-2glfA:
undetectable		 2g6hA-2glfA:
20.91
2g6hB-2glfA:
20.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2G6K_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 2glf PROBABLE M18-FAMILY
AMINOPEPTIDASE 1
(Thermotoga
maritima) 		4 / 7 ARG A 261
VAL A 443
PHE A  21
GLU A  17
 None
 1.26A 2g6kA-2glfA:
undetectable
2g6kB-2glfA:
undetectable		 2g6kA-2glfA:
20.91
2g6kB-2glfA:
20.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2G6M_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 2glf PROBABLE M18-FAMILY
AMINOPEPTIDASE 1
(Thermotoga
maritima) 		4 / 7 ARG A 261
VAL A 443
PHE A  21
GLU A  17
 None
 1.24A 2g6mA-2glfA:
undetectable
2g6mB-2glfA:
undetectable		 2g6mA-2glfA:
20.91
2g6mB-2glfA:
20.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2G6M_B_H4BB761_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 2glf PROBABLE M18-FAMILY
AMINOPEPTIDASE 1
(Thermotoga
maritima) 		4 / 7 PHE A  21
GLU A  17
ARG A 261
VAL A 443
 None
 1.26A 2g6mA-2glfA:
undetectable
2g6mB-2glfA:
undetectable		 2g6mA-2glfA:
20.91
2g6mB-2glfA:
20.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HX4_B_H4BB760_1
(NITRIC-OXIDE
SYNTHASE)		 2glf PROBABLE M18-FAMILY
AMINOPEPTIDASE 1
(Thermotoga
maritima) 		4 / 7 PHE A  21
GLU A  17
ARG A 261
VAL A 443
 None
 1.28A 2hx4A-2glfA:
undetectable
2hx4B-2glfA:
undetectable		 2hx4A-2glfA:
20.82
2hx4B-2glfA:
20.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q72_A_IXXA802_1
(TRANSPORTER)		 2glf PROBABLE M18-FAMILY
AMINOPEPTIDASE 1
(Thermotoga
maritima) 		4 / 6 ILE A  45
SER A  49
ARG A  79
PHE A 276
 None
 0.97A 2q72A-2glfA:
undetectable		 2q72A-2glfA:
24.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XFH_A_CL6A1414_1
(ERYTHROMYCIN B/D
C-12 HYDROXYLASE)		 2glf PROBABLE M18-FAMILY
AMINOPEPTIDASE 1
(Thermotoga
maritima) 		5 / 8 LEU A  84
ILE A 302
LEU A 299
THR A 322
LEU A  88
 None
 1.49A 2xfhA-2glfA:
undetectable		 2xfhA-2glfA:
22.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y7H_B_SAMB530_1
(TYPE I RESTRICTION
ENZYME ECOKI M
PROTEIN)		 2glf PROBABLE M18-FAMILY
AMINOPEPTIDASE 1
(Thermotoga
maritima) 		3 / 3 TYR A 121
GLU A 228
THR A  38
 None
 1.00A 2y7hB-2glfA:
undetectable		 2y7hB-2glfA:
22.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZM7_A_ACAA501_1
(6-AMINOHEXANOATE-DIM
ER HYDROLASE)		 2glf PROBABLE M18-FAMILY
AMINOPEPTIDASE 1
(Thermotoga
maritima) 		4 / 7 ALA A 247
TYR A  25
ILE A 432
ILE A 245
 None
 1.16A 2zm7A-2glfA:
undetectable		 2zm7A-2glfA:
23.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZM9_A_ACAA501_1
(6-AMINOHEXANOATE-DIM
ER HYDROLASE)		 2glf PROBABLE M18-FAMILY
AMINOPEPTIDASE 1
(Thermotoga
maritima) 		5 / 9 ALA A 247
TYR A  25
ILE A 432
GLY A 246
ILE A 245
 None
 1.19A 2zm9A-2glfA:
0.0		 2zm9A-2glfA:
22.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B3M_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE)		 2glf PROBABLE M18-FAMILY
AMINOPEPTIDASE 1
(Thermotoga
maritima) 		4 / 7 ARG A 261
VAL A 443
PHE A  21
GLU A  17
 None
 1.25A 3b3mA-2glfA:
undetectable
3b3mB-2glfA:
undetectable		 3b3mA-2glfA:
20.82
3b3mB-2glfA:
20.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B3M_B_H4BB760_1
(NITRIC-OXIDE
SYNTHASE)		 2glf PROBABLE M18-FAMILY
AMINOPEPTIDASE 1
(Thermotoga
maritima) 		4 / 7 PHE A  21
GLU A  17
ARG A 261
VAL A 443
 None
 1.22A 3b3mA-2glfA:
undetectable
3b3mB-2glfA:
undetectable		 3b3mA-2glfA:
20.82
3b3mB-2glfA:
20.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CZH_A_D2VA602_1
(CYTOCHROME P450 2R1)		 2glf PROBABLE M18-FAMILY
AMINOPEPTIDASE 1
(Thermotoga
maritima) 		5 / 12 THR A 441
VAL A 356
ALA A 392
VAL A 378
THR A 359
 None
 1.08A 3czhA-2glfA:
undetectable		 3czhA-2glfA:
22.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DL9_A_V2HA602_0
(CYTOCHROME P450 2R1)		 2glf PROBABLE M18-FAMILY
AMINOPEPTIDASE 1
(Thermotoga
maritima) 		5 / 12 THR A 441
VAL A 356
ALA A 392
VAL A 378
THR A 359
 None
 1.05A 3dl9A-2glfA:
undetectable		 3dl9A-2glfA:
22.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DQT_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 2glf PROBABLE M18-FAMILY
AMINOPEPTIDASE 1
(Thermotoga
maritima) 		4 / 7 PHE A 233
GLU A 431
SER A 428
TRP A 129
 None
 1.22A 3dqtA-2glfA:
undetectable
3dqtB-2glfA:
undetectable		 3dqtA-2glfA:
21.41
3dqtB-2glfA:
21.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FC5_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2glf PROBABLE M18-FAMILY
AMINOPEPTIDASE 1
(Thermotoga
maritima) 		4 / 7 ARG A 261
VAL A 443
PHE A  21
GLU A  17
 None
 1.27A 3fc5A-2glfA:
undetectable
3fc5B-2glfA:
undetectable		 3fc5A-2glfA:
21.19
3fc5B-2glfA:
21.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FC5_B_H4BB761_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2glf PROBABLE M18-FAMILY
AMINOPEPTIDASE 1
(Thermotoga
maritima) 		4 / 7 PHE A  21
GLU A  17
ARG A 261
VAL A 443
 None
 1.25A 3fc5A-2glfA:
undetectable
3fc5B-2glfA:
undetectable		 3fc5A-2glfA:
21.19
3fc5B-2glfA:
21.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HSN_B_H4BB1760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2glf PROBABLE M18-FAMILY
AMINOPEPTIDASE 1
(Thermotoga
maritima) 		4 / 7 PHE A  21
GLU A  17
ARG A 261
VAL A 443
 None
 1.27A 3hsnA-2glfA:
undetectable
3hsnB-2glfA:
undetectable		 3hsnA-2glfA:
20.82
3hsnB-2glfA:
20.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HSO_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2glf PROBABLE M18-FAMILY
AMINOPEPTIDASE 1
(Thermotoga
maritima) 		4 / 7 ARG A 261
VAL A 443
PHE A  21
GLU A  17
 None
 1.26A 3hsoA-2glfA:
undetectable
3hsoB-2glfA:
undetectable		 3hsoA-2glfA:
20.82
3hsoB-2glfA:
20.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HSP_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2glf PROBABLE M18-FAMILY
AMINOPEPTIDASE 1
(Thermotoga
maritima) 		4 / 7 ARG A 261
VAL A 443
PHE A  21
GLU A  17
 None
 1.27A 3hspA-2glfA:
undetectable
3hspB-2glfA:
undetectable		 3hspA-2glfA:
20.82
3hspB-2glfA:
20.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JT6_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2glf PROBABLE M18-FAMILY
AMINOPEPTIDASE 1
(Thermotoga
maritima) 		4 / 7 PHE A  21
GLU A  17
ARG A 261
VAL A 443
 None
 1.25A 3jt6A-2glfA:
undetectable
3jt6B-2glfA:
undetectable		 3jt6A-2glfA:
20.82
3jt6B-2glfA:
20.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JWT_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2glf PROBABLE M18-FAMILY
AMINOPEPTIDASE 1
(Thermotoga
maritima) 		4 / 7 ARG A 261
VAL A 443
PHE A  21
GLU A  17
 None
 1.25A 3jwtA-2glfA:
undetectable
3jwtB-2glfA:
undetectable		 3jwtA-2glfA:
20.25
3jwtB-2glfA:
20.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JX0_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2glf PROBABLE M18-FAMILY
AMINOPEPTIDASE 1
(Thermotoga
maritima) 		4 / 7 PHE A  21
GLU A  17
ARG A 261
VAL A 443
 None
 1.28A 3jx0A-2glfA:
undetectable
3jx0B-2glfA:
undetectable		 3jx0A-2glfA:
20.82
3jx0B-2glfA:
20.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JX1_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2glf PROBABLE M18-FAMILY
AMINOPEPTIDASE 1
(Thermotoga
maritima) 		4 / 8 PHE A  21
GLU A  17
ARG A 261
VAL A 443
 None
 1.26A 3jx1A-2glfA:
undetectable
3jx1B-2glfA:
undetectable		 3jx1A-2glfA:
20.82
3jx1B-2glfA:
20.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JX3_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2glf PROBABLE M18-FAMILY
AMINOPEPTIDASE 1
(Thermotoga
maritima) 		4 / 7 PHE A  21
GLU A  17
ARG A 261
VAL A 443
 None
 1.25A 3jx3A-2glfA:
0.0
3jx3B-2glfA:
undetectable		 3jx3A-2glfA:
20.82
3jx3B-2glfA:
20.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3L4D_D_TPFD490_1
(STEROL 14-ALPHA
DEMETHYLASE)		 2glf PROBABLE M18-FAMILY
AMINOPEPTIDASE 1
(Thermotoga
maritima) 		4 / 8 ALA A  68
ALA A 298
LEU A  84
MET A 305
 None
 0.99A 3l4dD-2glfA:
undetectable		 3l4dD-2glfA:
21.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLP_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2glf PROBABLE M18-FAMILY
AMINOPEPTIDASE 1
(Thermotoga
maritima) 		4 / 7 PHE A  21
GLU A  17
ARG A 261
VAL A 443
 None
 1.25A 3nlpA-2glfA:
undetectable
3nlpB-2glfA:
undetectable		 3nlpA-2glfA:
20.82
3nlpB-2glfA:
20.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLR_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2glf PROBABLE M18-FAMILY
AMINOPEPTIDASE 1
(Thermotoga
maritima) 		4 / 7 ARG A 261
VAL A 443
PHE A  21
GLU A  17
 None
 1.20A 3nlrA-2glfA:
undetectable
3nlrB-2glfA:
undetectable		 3nlrA-2glfA:
20.82
3nlrB-2glfA:
20.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLY_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2glf PROBABLE M18-FAMILY
AMINOPEPTIDASE 1
(Thermotoga
maritima) 		4 / 8 PHE A  21
GLU A  17
ARG A 261
VAL A 443
 None
 1.26A 3nlyA-2glfA:
undetectable
3nlyB-2glfA:
undetectable		 3nlyA-2glfA:
20.82
3nlyB-2glfA:
20.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLZ_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2glf PROBABLE M18-FAMILY
AMINOPEPTIDASE 1
(Thermotoga
maritima) 		4 / 7 PHE A  21
GLU A  17
ARG A 261
VAL A 443
 None
 1.25A 3nlzA-2glfA:
undetectable
3nlzB-2glfA:
undetectable		 3nlzA-2glfA:
20.82
3nlzB-2glfA:
20.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PNG_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2glf PROBABLE M18-FAMILY
AMINOPEPTIDASE 1
(Thermotoga
maritima) 		4 / 7 PHE A  21
GLU A  17
ARG A 261
VAL A 443
 None
 1.24A 3pngA-2glfA:
undetectable
3pngB-2glfA:
undetectable		 3pngA-2glfA:
20.82
3pngB-2glfA:
20.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3Q9A_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2glf PROBABLE M18-FAMILY
AMINOPEPTIDASE 1
(Thermotoga
maritima) 		4 / 7 ARG A 261
VAL A 443
PHE A  21
GLU A  17
 None
 1.26A 3q9aA-2glfA:
undetectable
3q9aB-2glfA:
undetectable		 3q9aA-2glfA:
20.82
3q9aB-2glfA:
20.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QPS_A_CHDA211_0
(CMER)		 2glf PROBABLE M18-FAMILY
AMINOPEPTIDASE 1
(Thermotoga
maritima) 		5 / 10 PHE A  51
ALA A  77
PHE A  78
GLY A 273
ILE A 272
 None
 1.38A 3qpsA-2glfA:
undetectable		 3qpsA-2glfA:
20.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T3Q_A_9PLA501_1
(CYTOCHROME P450 2A6)		 2glf PROBABLE M18-FAMILY
AMINOPEPTIDASE 1
(Thermotoga
maritima) 		5 / 10 PHE A 102
PHE A 222
PHE A 161
ALA A 190
ILE A 210
 None
 1.11A 3t3qA-2glfA:
undetectable		 3t3qA-2glfA:
22.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T3Q_B_9PLB501_1
(CYTOCHROME P450 2A6)		 2glf PROBABLE M18-FAMILY
AMINOPEPTIDASE 1
(Thermotoga
maritima) 		5 / 10 PHE A 102
PHE A 222
PHE A 161
ALA A 190
ILE A 210
 None
 1.06A 3t3qB-2glfA:
undetectable		 3t3qB-2glfA:
22.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T3Q_C_9PLC501_1
(CYTOCHROME P450 2A6)		 2glf PROBABLE M18-FAMILY
AMINOPEPTIDASE 1
(Thermotoga
maritima) 		5 / 10 PHE A 102
PHE A 222
PHE A 161
ALA A 190
ILE A 210
 None
 1.07A 3t3qC-2glfA:
undetectable		 3t3qC-2glfA:
22.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T3Q_D_9PLD501_1
(CYTOCHROME P450 2A6)		 2glf PROBABLE M18-FAMILY
AMINOPEPTIDASE 1
(Thermotoga
maritima) 		5 / 10 PHE A 102
PHE A 222
PHE A 161
ALA A 190
ILE A 210
 None
 1.10A 3t3qD-2glfA:
undetectable		 3t3qD-2glfA:
22.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TYM_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2glf PROBABLE M18-FAMILY
AMINOPEPTIDASE 1
(Thermotoga
maritima) 		4 / 7 PHE A  21
GLU A  17
ARG A 261
VAL A 443
 None
 1.25A 3tymA-2glfA:
undetectable
3tymB-2glfA:
undetectable		 3tymA-2glfA:
20.82
3tymB-2glfA:
20.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UAW_A_ADNA236_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE)		 2glf PROBABLE M18-FAMILY
AMINOPEPTIDASE 1
(Thermotoga
maritima) 		5 / 11 GLY A 246
VAL A 238
GLU A 237
GLU A  19
ILE A 432
 None
 1.14A 3uawA-2glfA:
undetectable		 3uawA-2glfA:
20.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UAY_A_ADNA236_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE)		 2glf PROBABLE M18-FAMILY
AMINOPEPTIDASE 1
(Thermotoga
maritima) 		5 / 10 GLY A 246
VAL A 238
GLU A 237
GLU A  19
ILE A 432
 None
 1.11A 3uayA-2glfA:
7.2		 3uayA-2glfA:
20.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFU_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2glf PROBABLE M18-FAMILY
AMINOPEPTIDASE 1
(Thermotoga
maritima) 		4 / 7 PHE A  21
GLU A  17
ARG A 261
VAL A 443
 None
 1.26A 3ufuA-2glfA:
undetectable
3ufuB-2glfA:
undetectable		 3ufuA-2glfA:
20.82
3ufuB-2glfA:
20.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFV_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2glf PROBABLE M18-FAMILY
AMINOPEPTIDASE 1
(Thermotoga
maritima) 		4 / 7 PHE A  21
GLU A  17
ARG A 261
VAL A 443
 None
 1.25A 3ufvA-2glfA:
undetectable
3ufvB-2glfA:
undetectable		 3ufvA-2glfA:
20.82
3ufvB-2glfA:
20.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C5N_A_PXLA300_1
(PHOSPHOMETHYLPYRIMID
INE KINASE)		 2glf PROBABLE M18-FAMILY
AMINOPEPTIDASE 1
(Thermotoga
maritima) 		4 / 7 GLY A 420
ASP A 328
GLY A 327
HIS A  94
 None
MN  A5001 (-2.2A)
None
MN  A5001 (-3.6A)
 0.81A 4c5nA-2glfA:
undetectable		 4c5nA-2glfA:
23.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C5N_C_PXLC300_1
(PHOSPHOMETHYLPYRIMID
INE KINASE)		 2glf PROBABLE M18-FAMILY
AMINOPEPTIDASE 1
(Thermotoga
maritima) 		4 / 8 GLY A 420
ASP A 328
GLY A 327
HIS A  94
 None
MN  A5001 (-2.2A)
None
MN  A5001 (-3.6A)
 0.76A 4c5nC-2glfA:
undetectable		 4c5nC-2glfA:
23.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CAN_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2glf PROBABLE M18-FAMILY
AMINOPEPTIDASE 1
(Thermotoga
maritima) 		4 / 7 ARG A 261
VAL A 443
PHE A  21
GLU A  17
 None
 1.26A 4canA-2glfA:
undetectable
4canB-2glfA:
undetectable		 4canA-2glfA:
20.82
4canB-2glfA:
20.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CTR_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2glf PROBABLE M18-FAMILY
AMINOPEPTIDASE 1
(Thermotoga
maritima) 		4 / 7 ARG A 261
VAL A 443
PHE A  21
GLU A  17
 None
 1.21A 4ctrA-2glfA:
undetectable
4ctrB-2glfA:
undetectable		 4ctrA-2glfA:
20.82
4ctrB-2glfA:
20.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CTU_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2glf PROBABLE M18-FAMILY
AMINOPEPTIDASE 1
(Thermotoga
maritima) 		4 / 7 PHE A  21
GLU A  17
ARG A 261
VAL A 443
 None
 1.26A 4ctuA-2glfA:
undetectable
4ctuB-2glfA:
0.0		 4ctuA-2glfA:
20.82
4ctuB-2glfA:
20.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CTW_A_H4BA1718_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2glf PROBABLE M18-FAMILY
AMINOPEPTIDASE 1
(Thermotoga
maritima) 		4 / 7 ARG A 261
VAL A 443
PHE A  21
GLU A  17
 None
 1.26A 4ctwA-2glfA:
undetectable
4ctwB-2glfA:
undetectable		 4ctwA-2glfA:
20.82
4ctwB-2glfA:
20.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CX7_C_H4BC600_1
(NITRIC OXIDE
SYNTHASE, INDUCIBLE)		 2glf PROBABLE M18-FAMILY
AMINOPEPTIDASE 1
(Thermotoga
maritima) 		4 / 8 SER A 428
TRP A 129
PHE A 233
GLU A 431
 None
 1.14A 4cx7C-2glfA:
undetectable
4cx7D-2glfA:
undetectable		 4cx7C-2glfA:
21.64
4cx7D-2glfA:
21.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D1N_C_H4BC760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2glf PROBABLE M18-FAMILY
AMINOPEPTIDASE 1
(Thermotoga
maritima) 		4 / 7 ARG A 261
VAL A 443
PHE A  21
GLU A  17
 None
 1.26A 4d1nC-2glfA:
undetectable
4d1nD-2glfA:
undetectable		 4d1nC-2glfA:
23.42
4d1nD-2glfA:
23.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D2Y_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2glf PROBABLE M18-FAMILY
AMINOPEPTIDASE 1
(Thermotoga
maritima) 		4 / 7 ARG A 261
VAL A 443
PHE A  21
GLU A  17
 None
 1.26A 4d2yA-2glfA:
undetectable
4d2yB-2glfA:
undetectable		 4d2yA-2glfA:
20.82
4d2yB-2glfA:
20.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D2Y_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2glf PROBABLE M18-FAMILY
AMINOPEPTIDASE 1
(Thermotoga
maritima) 		4 / 7 PHE A  21
GLU A  17
ARG A 261
VAL A 443
 None
 1.27A 4d2yA-2glfA:
undetectable
4d2yB-2glfA:
undetectable		 4d2yA-2glfA:
20.82
4d2yB-2glfA:
20.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D30_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2glf PROBABLE M18-FAMILY
AMINOPEPTIDASE 1
(Thermotoga
maritima) 		4 / 7 PHE A  21
GLU A  17
ARG A 261
VAL A 443
 None
 1.28A 4d30A-2glfA:
undetectable
4d30B-2glfA:
undetectable		 4d30A-2glfA:
20.82
4d30B-2glfA:
20.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D3B_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2glf PROBABLE M18-FAMILY
AMINOPEPTIDASE 1
(Thermotoga
maritima) 		4 / 7 PHE A  21
GLU A  17
ARG A 261
VAL A 443
 None
 1.24A 4d3bA-2glfA:
undetectable
4d3bB-2glfA:
undetectable		 4d3bA-2glfA:
20.82
4d3bB-2glfA:
20.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FVZ_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2glf PROBABLE M18-FAMILY
AMINOPEPTIDASE 1
(Thermotoga
maritima) 		4 / 7 ARG A 261
VAL A 443
PHE A  21
GLU A  17
 None
 1.26A 4fvzA-2glfA:
undetectable
4fvzB-2glfA:
undetectable		 4fvzA-2glfA:
20.82
4fvzB-2glfA:
20.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HVR_A_SALA203_1
(3-HYDROXYANTHRANILAT
E 3,4-DIOXYGENASE)		 2glf PROBABLE M18-FAMILY
AMINOPEPTIDASE 1
(Thermotoga
maritima) 		4 / 7 ASP A 251
GLU A 281
HIS A 427
GLU A 280
 MN  A5002 ( 2.7A)
MN  A5002 (-2.1A)
MN  A5002 (-3.6A)
MN  A5001 (-4.4A)
 1.04A 4hvrA-2glfA:
undetectable		 4hvrA-2glfA:
15.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JSF_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2glf PROBABLE M18-FAMILY
AMINOPEPTIDASE 1
(Thermotoga
maritima) 		4 / 7 PHE A  21
GLU A  17
ARG A 261
VAL A 443
 None
 1.26A 4jsfA-2glfA:
undetectable
4jsfB-2glfA:
undetectable		 4jsfA-2glfA:
20.82
4jsfB-2glfA:
20.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K5J_B_H4BB502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 2glf PROBABLE M18-FAMILY
AMINOPEPTIDASE 1
(Thermotoga
maritima) 		4 / 7 PHE A 233
GLU A 431
SER A 428
TRP A 129
 None
 1.19A 4k5jA-2glfA:
undetectable
4k5jB-2glfA:
undetectable		 4k5jA-2glfA:
21.34
4k5jB-2glfA:
21.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCM_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2glf PROBABLE M18-FAMILY
AMINOPEPTIDASE 1
(Thermotoga
maritima) 		4 / 7 ARG A 261
VAL A 443
PHE A  21
GLU A  17
 None
 1.26A 4kcmA-2glfA:
undetectable
4kcmB-2glfA:
undetectable		 4kcmA-2glfA:
20.82
4kcmB-2glfA:
20.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PQA_A_X8ZA401_1
(SUCCINYL-DIAMINOPIME
LATE DESUCCINYLASE)		 2glf PROBABLE M18-FAMILY
AMINOPEPTIDASE 1
(Thermotoga
maritima) 		7 / 11 HIS A  94
ASP A 251
GLU A 280
GLU A 281
GLY A 401
GLY A 402
HIS A 427
 MN  A5001 (-3.6A)
MN  A5002 ( 2.7A)
MN  A5001 (-4.4A)
MN  A5002 (-2.1A)
None
None
MN  A5002 (-3.6A)
 1.22A 4pqaA-2glfA:
20.8		 4pqaA-2glfA:
23.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R88_C_1LDC501_0
(CYTOSINE DEAMINASE)		 2glf PROBABLE M18-FAMILY
AMINOPEPTIDASE 1
(Thermotoga
maritima) 		5 / 12 LEU A 211
PHE A 102
ILE A 136
GLU A 219
LEU A 208
 None
 1.48A 4r88C-2glfA:
undetectable		 4r88C-2glfA:
21.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UCH_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2glf PROBABLE M18-FAMILY
AMINOPEPTIDASE 1
(Thermotoga
maritima) 		4 / 7 ARG A 261
VAL A 443
PHE A  21
GLU A  17
 None
 1.27A 4uchA-2glfA:
undetectable
4uchB-2glfA:
undetectable		 4uchA-2glfA:
23.25
4uchB-2glfA:
23.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UH3_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2glf PROBABLE M18-FAMILY
AMINOPEPTIDASE 1
(Thermotoga
maritima) 		4 / 7 PHE A  21
GLU A  17
ARG A 261
VAL A 443
 None
 1.28A 4uh3A-2glfA:
undetectable
4uh3B-2glfA:
undetectable		 4uh3A-2glfA:
20.82
4uh3B-2glfA:
20.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UH5_A_H4BA760_1
(NEURONAL NITRIC
OXIDE SYNTHASE)		 2glf PROBABLE M18-FAMILY
AMINOPEPTIDASE 1
(Thermotoga
maritima) 		4 / 7 ARG A 261
VAL A 443
PHE A  21
GLU A  17
 None
 1.27A 4uh5A-2glfA:
undetectable
4uh5B-2glfA:
undetectable		 4uh5A-2glfA:
23.30
4uh5B-2glfA:
23.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UH6_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2glf PROBABLE M18-FAMILY
AMINOPEPTIDASE 1
(Thermotoga
maritima) 		4 / 7 ARG A 261
VAL A 443
PHE A  21
GLU A  17
 None
 1.24A 4uh6A-2glfA:
undetectable
4uh6B-2glfA:
undetectable		 4uh6A-2glfA:
23.30
4uh6B-2glfA:
23.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UPP_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2glf PROBABLE M18-FAMILY
AMINOPEPTIDASE 1
(Thermotoga
maritima) 		4 / 7 ARG A 261
VAL A 443
PHE A  21
GLU A  17
 None
 1.25A 4uppA-2glfA:
undetectable
4uppB-2glfA:
undetectable		 4uppA-2glfA:
20.82
4uppB-2glfA:
20.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V3U_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2glf PROBABLE M18-FAMILY
AMINOPEPTIDASE 1
(Thermotoga
maritima) 		4 / 7 ARG A 261
VAL A 443
PHE A  21
GLU A  17
 None
 1.25A 4v3uA-2glfA:
undetectable
4v3uB-2glfA:
undetectable		 4v3uA-2glfA:
23.42
4v3uB-2glfA:
23.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V3U_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2glf PROBABLE M18-FAMILY
AMINOPEPTIDASE 1
(Thermotoga
maritima) 		4 / 7 PHE A  21
GLU A  17
ARG A 261
VAL A 443
 None
 1.29A 4v3uA-2glfA:
undetectable
4v3uB-2glfA:
undetectable		 4v3uA-2glfA:
23.42
4v3uB-2glfA:
23.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V3U_C_H4BC760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2glf PROBABLE M18-FAMILY
AMINOPEPTIDASE 1
(Thermotoga
maritima) 		4 / 7 ARG A 261
VAL A 443
PHE A  21
GLU A  17
 None
 1.28A 4v3uC-2glfA:
undetectable
4v3uD-2glfA:
undetectable		 4v3uC-2glfA:
23.42
4v3uD-2glfA:
23.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V3U_D_H4BD760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2glf PROBABLE M18-FAMILY
AMINOPEPTIDASE 1
(Thermotoga
maritima) 		4 / 7 PHE A  21
GLU A  17
ARG A 261
VAL A 443
 None
 1.23A 4v3uC-2glfA:
undetectable
4v3uD-2glfA:
undetectable		 4v3uC-2glfA:
23.42
4v3uD-2glfA:
23.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V3W_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2glf PROBABLE M18-FAMILY
AMINOPEPTIDASE 1
(Thermotoga
maritima) 		4 / 7 PHE A  21
GLU A  17
ARG A 261
VAL A 443
 None
 1.18A 4v3wA-2glfA:
undetectable
4v3wB-2glfA:
undetectable		 4v3wA-2glfA:
20.82
4v3wB-2glfA:
20.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V3X_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2glf PROBABLE M18-FAMILY
AMINOPEPTIDASE 1
(Thermotoga
maritima) 		4 / 7 PHE A  21
GLU A  17
ARG A 261
VAL A 443
 None
 1.27A 4v3xA-2glfA:
undetectable
4v3xB-2glfA:
undetectable		 4v3xA-2glfA:
20.82
4v3xB-2glfA:
20.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V3Z_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2glf PROBABLE M18-FAMILY
AMINOPEPTIDASE 1
(Thermotoga
maritima) 		4 / 6 ARG A 261
VAL A 443
PHE A  21
GLU A  17
 None
 1.23A 4v3zA-2glfA:
undetectable
4v3zB-2glfA:
undetectable		 4v3zA-2glfA:
20.82
4v3zB-2glfA:
20.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V3Z_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2glf PROBABLE M18-FAMILY
AMINOPEPTIDASE 1
(Thermotoga
maritima) 		4 / 7 PHE A  21
GLU A  17
ARG A 261
VAL A 443
 None
 1.24A 4v3zA-2glfA:
undetectable
4v3zB-2glfA:
undetectable		 4v3zA-2glfA:
20.82
4v3zB-2glfA:
20.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ADB_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2glf PROBABLE M18-FAMILY
AMINOPEPTIDASE 1
(Thermotoga
maritima) 		4 / 6 PHE A  21
GLU A  17
ARG A 261
VAL A 443
 None
 1.25A 5adbA-2glfA:
undetectable
5adbB-2glfA:
undetectable		 5adbA-2glfA:
20.82
5adbB-2glfA:
20.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ADC_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2glf PROBABLE M18-FAMILY
AMINOPEPTIDASE 1
(Thermotoga
maritima) 		4 / 7 PHE A  21
GLU A  17
ARG A 261
VAL A 443
 None
 1.25A 5adcA-2glfA:
undetectable
5adcB-2glfA:
undetectable		 5adcA-2glfA:
20.82
5adcB-2glfA:
20.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ADD_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2glf PROBABLE M18-FAMILY
AMINOPEPTIDASE 1
(Thermotoga
maritima) 		4 / 7 PHE A  21
GLU A  17
ARG A 261
VAL A 443
 None
 1.24A 5addA-2glfA:
undetectable
5addB-2glfA:
undetectable		 5addA-2glfA:
20.82
5addB-2glfA:
20.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AGN_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2glf PROBABLE M18-FAMILY
AMINOPEPTIDASE 1
(Thermotoga
maritima) 		4 / 7 PHE A  21
GLU A  17
ARG A 261
VAL A 443
 None
 1.26A 5agnA-2glfA:
undetectable
5agnB-2glfA:
undetectable		 5agnA-2glfA:
20.82
5agnB-2glfA:
20.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FVQ_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2glf PROBABLE M18-FAMILY
AMINOPEPTIDASE 1
(Thermotoga
maritima) 		4 / 6 ARG A 261
VAL A 443
PHE A  21
GLU A  17
 None
 1.25A 5fvqA-2glfA:
undetectable
5fvqB-2glfA:
undetectable		 5fvqA-2glfA:
20.82
5fvqB-2glfA:
20.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FVR_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2glf PROBABLE M18-FAMILY
AMINOPEPTIDASE 1
(Thermotoga
maritima) 		4 / 6 PHE A  21
GLU A  17
ARG A 261
VAL A 443
 None
 1.28A 5fvrA-2glfA:
undetectable
5fvrB-2glfA:
undetectable		 5fvrA-2glfA:
20.82
5fvrB-2glfA:
20.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FVS_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2glf PROBABLE M18-FAMILY
AMINOPEPTIDASE 1
(Thermotoga
maritima) 		4 / 7 PHE A  21
GLU A  17
ARG A 261
VAL A 443
 None
 1.29A 5fvsA-2glfA:
undetectable
5fvsB-2glfA:
undetectable		 5fvsA-2glfA:
20.82
5fvsB-2glfA:
20.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FVT_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2glf PROBABLE M18-FAMILY
AMINOPEPTIDASE 1
(Thermotoga
maritima) 		4 / 7 ARG A 261
VAL A 443
PHE A  21
GLU A  17
 None
 1.26A 5fvtA-2glfA:
undetectable
5fvtB-2glfA:
undetectable		 5fvtA-2glfA:
20.82
5fvtB-2glfA:
20.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FVT_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2glf PROBABLE M18-FAMILY
AMINOPEPTIDASE 1
(Thermotoga
maritima) 		4 / 7 PHE A  21
GLU A  17
ARG A 261
VAL A 443
 None
 1.25A 5fvtA-2glfA:
undetectable
5fvtB-2glfA:
undetectable		 5fvtA-2glfA:
20.82
5fvtB-2glfA:
20.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FVU_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2glf PROBABLE M18-FAMILY
AMINOPEPTIDASE 1
(Thermotoga
maritima) 		4 / 6 ARG A 261
VAL A 443
PHE A  21
GLU A  17
 None
 1.24A 5fvuA-2glfA:
undetectable
5fvuB-2glfA:
undetectable		 5fvuA-2glfA:
23.30
5fvuB-2glfA:
23.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FVV_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2glf PROBABLE M18-FAMILY
AMINOPEPTIDASE 1
(Thermotoga
maritima) 		4 / 7 ARG A 261
VAL A 443
PHE A  21
GLU A  17
 None
 1.27A 5fvvA-2glfA:
undetectable
5fvvB-2glfA:
undetectable		 5fvvA-2glfA:
23.30
5fvvB-2glfA:
23.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FVW_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2glf PROBABLE M18-FAMILY
AMINOPEPTIDASE 1
(Thermotoga
maritima) 		4 / 7 ARG A 261
VAL A 443
PHE A  21
GLU A  17
 None
 1.24A 5fvwA-2glfA:
undetectable
5fvwB-2glfA:
undetectable		 5fvwA-2glfA:
23.30
5fvwB-2glfA:
23.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FVX_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2glf PROBABLE M18-FAMILY
AMINOPEPTIDASE 1
(Thermotoga
maritima) 		4 / 7 ARG A 261
VAL A 443
PHE A  21
GLU A  17
 None
 1.25A 5fvxA-2glfA:
undetectable
5fvxB-2glfA:
undetectable		 5fvxA-2glfA:
23.30
5fvxB-2glfA:
23.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G0N_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2glf PROBABLE M18-FAMILY
AMINOPEPTIDASE 1
(Thermotoga
maritima) 		4 / 7 ARG A 261
VAL A 443
PHE A  21
GLU A  17
 None
 1.24A 5g0nA-2glfA:
undetectable
5g0nB-2glfA:
undetectable		 5g0nA-2glfA:
20.82
5g0nB-2glfA:
20.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G0N_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2glf PROBABLE M18-FAMILY
AMINOPEPTIDASE 1
(Thermotoga
maritima) 		4 / 7 PHE A  21
GLU A  17
ARG A 261
VAL A 443
 None
 1.26A 5g0nA-2glfA:
undetectable
5g0nB-2glfA:
undetectable		 5g0nA-2glfA:
20.82
5g0nB-2glfA:
20.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3C_B_AC2B301_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE)		 2glf PROBABLE M18-FAMILY
AMINOPEPTIDASE 1
(Thermotoga
maritima) 		5 / 10 GLY A 246
VAL A 238
GLU A 237
GLU A  19
ILE A 432
 None
 1.06A 5i3cB-2glfA:
7.0		 5i3cB-2glfA:
21.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3C_C_AC2C301_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE)		 2glf PROBABLE M18-FAMILY
AMINOPEPTIDASE 1
(Thermotoga
maritima) 		5 / 11 GLY A 246
VAL A 238
GLU A 237
GLU A  19
ILE A 432
 None
 1.10A 5i3cC-2glfA:
6.0		 5i3cC-2glfA:
21.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UNT_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2glf PROBABLE M18-FAMILY
AMINOPEPTIDASE 1
(Thermotoga
maritima) 		4 / 7 ARG A 261
VAL A 443
PHE A  21
GLU A  17
 None
 1.22A 5untA-2glfA:
undetectable
5untB-2glfA:
undetectable		 5untA-2glfA:
20.82
5untB-2glfA:
20.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UNT_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2glf PROBABLE M18-FAMILY
AMINOPEPTIDASE 1
(Thermotoga
maritima) 		4 / 7 PHE A  21
GLU A  17
ARG A 261
VAL A 443
 None
 1.24A 5untA-2glfA:
undetectable
5untB-2glfA:
undetectable		 5untA-2glfA:
20.82
5untB-2glfA:
20.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UNW_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2glf PROBABLE M18-FAMILY
AMINOPEPTIDASE 1
(Thermotoga
maritima) 		4 / 7 PHE A  21
GLU A  17
ARG A 261
VAL A 443
 None
 1.29A 5unwA-2glfA:
undetectable
5unwB-2glfA:
undetectable		 5unwA-2glfA:
20.82
5unwB-2glfA:
20.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UO5_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2glf PROBABLE M18-FAMILY
AMINOPEPTIDASE 1
(Thermotoga
maritima) 		4 / 7 ARG A 261
VAL A 443
PHE A  21
GLU A  17
 None
 1.26A 5uo5A-2glfA:
undetectable
5uo5B-2glfA:
undetectable		 5uo5A-2glfA:
23.30
5uo5B-2glfA:
23.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UO7_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2glf PROBABLE M18-FAMILY
AMINOPEPTIDASE 1
(Thermotoga
maritima) 		4 / 8 ARG A 261
VAL A 443
PHE A  21
GLU A  17
 None
 1.21A 5uo7A-2glfA:
undetectable
5uo7B-2glfA:
undetectable		 5uo7A-2glfA:
23.30
5uo7B-2glfA:
23.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VOO_B_C2FB702_0
(5-METHYLTETRAHYDROFO
LATE HOMOCYSTEINE
S-METHYLTRANSFERASE)		 2glf PROBABLE M18-FAMILY
AMINOPEPTIDASE 1
(Thermotoga
maritima) 		5 / 12 GLY A 249
LYS A  33
VAL A 356
LEU A 394
SER A 433
 None
 1.15A 5vooB-2glfA:
undetectable		 5vooB-2glfA:
21.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VOO_D_C2FD3001_0
(5-METHYLTETRAHYDROFO
LATE HOMOCYSTEINE
S-METHYLTRANSFERASE)		 2glf PROBABLE M18-FAMILY
AMINOPEPTIDASE 1
(Thermotoga
maritima) 		5 / 12 GLY A 249
LYS A  33
VAL A 356
LEU A 394
SER A 433
 None
 1.18A 5vooD-2glfA:
undetectable		 5vooD-2glfA:
21.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VOO_E_C2FE3001_0
(5-METHYLTETRAHYDROFO
LATE HOMOCYSTEINE
S-METHYLTRANSFERASE)		 2glf PROBABLE M18-FAMILY
AMINOPEPTIDASE 1
(Thermotoga
maritima) 		5 / 12 GLY A 249
LYS A  33
VAL A 356
LEU A 394
SER A 433
 None
 1.17A 5vooE-2glfA:
undetectable		 5vooE-2glfA:
21.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUI_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2glf PROBABLE M18-FAMILY
AMINOPEPTIDASE 1
(Thermotoga
maritima) 		4 / 7 PHE A  21
GLU A  17
ARG A 261
VAL A 443
 None
 1.27A 5vuiA-2glfA:
undetectable
5vuiB-2glfA:
undetectable		 5vuiA-2glfA:
20.82
5vuiB-2glfA:
20.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUJ_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2glf PROBABLE M18-FAMILY
AMINOPEPTIDASE 1
(Thermotoga
maritima) 		4 / 7 PHE A  21
GLU A  17
ARG A 261
VAL A 443
 None
 1.21A 5vujA-2glfA:
undetectable
5vujB-2glfA:
0.0		 5vujA-2glfA:
20.82
5vujB-2glfA:
20.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUL_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2glf PROBABLE M18-FAMILY
AMINOPEPTIDASE 1
(Thermotoga
maritima) 		4 / 7 PHE A  21
GLU A  17
ARG A 261
VAL A 443
 None
 1.26A 5vulA-2glfA:
undetectable
5vulB-2glfA:
undetectable		 5vulA-2glfA:
20.82
5vulB-2glfA:
20.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUM_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2glf PROBABLE M18-FAMILY
AMINOPEPTIDASE 1
(Thermotoga
maritima) 		4 / 7 PHE A  21
GLU A  17
ARG A 261
VAL A 443
 None
 1.24A 5vumA-2glfA:
undetectable
5vumB-2glfA:
undetectable		 5vumA-2glfA:
20.82
5vumB-2glfA:
20.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUN_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2glf PROBABLE M18-FAMILY
AMINOPEPTIDASE 1
(Thermotoga
maritima) 		4 / 7 PHE A  21
GLU A  17
ARG A 261
VAL A 443
 None
 1.25A 5vunA-2glfA:
undetectable
5vunB-2glfA:
undetectable		 5vunA-2glfA:
20.82
5vunB-2glfA:
20.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUO_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2glf PROBABLE M18-FAMILY
AMINOPEPTIDASE 1
(Thermotoga
maritima) 		4 / 7 PHE A  21
GLU A  17
ARG A 261
VAL A 443
 None
 1.25A 5vuoA-2glfA:
undetectable
5vuoB-2glfA:
undetectable		 5vuoA-2glfA:
20.82
5vuoB-2glfA:
20.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUP_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2glf PROBABLE M18-FAMILY
AMINOPEPTIDASE 1
(Thermotoga
maritima) 		4 / 7 PHE A  21
GLU A  17
ARG A 261
VAL A 443
 None
 1.26A 5vupA-2glfA:
undetectable
5vupB-2glfA:
undetectable		 5vupA-2glfA:
20.82
5vupB-2glfA:
20.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUT_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2glf PROBABLE M18-FAMILY
AMINOPEPTIDASE 1
(Thermotoga
maritima) 		4 / 7 PHE A  21
GLU A  17
ARG A 261
VAL A 443
 None
 1.24A 5vutA-2glfA:
undetectable
5vutB-2glfA:
undetectable		 5vutA-2glfA:
20.82
5vutB-2glfA:
20.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VV1_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2glf PROBABLE M18-FAMILY
AMINOPEPTIDASE 1
(Thermotoga
maritima) 		4 / 6 ARG A 261
VAL A 443
PHE A  21
GLU A  17
 None
 1.27A 5vv1A-2glfA:
undetectable
5vv1B-2glfA:
undetectable		 5vv1A-2glfA:
23.30
5vv1B-2glfA:
23.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VV2_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2glf PROBABLE M18-FAMILY
AMINOPEPTIDASE 1
(Thermotoga
maritima) 		4 / 7 ARG A 261
VAL A 443
PHE A  21
GLU A  17
 None
 1.25A 5vv2A-2glfA:
undetectable
5vv2B-2glfA:
undetectable		 5vv2A-2glfA:
23.30
5vv2B-2glfA:
23.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VVN_B_H4BB502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 2glf PROBABLE M18-FAMILY
AMINOPEPTIDASE 1
(Thermotoga
maritima) 		4 / 7 PHE A 233
GLU A 431
SER A 428
TRP A 129
 None
 1.24A 5vvnA-2glfA:
undetectable
5vvnB-2glfA:
undetectable		 5vvnA-2glfA:
21.34
5vvnB-2glfA:
21.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZRF_D_EVPD101_1
()		 2glf PROBABLE M18-FAMILY
AMINOPEPTIDASE 1
(Thermotoga
maritima) 		4 / 5 ASP A 310
ARG A 300
GLN A 306
MET A  64
 None
 1.46A 5zrfB-2glfA:
2.8		 5zrfB-2glfA:
22.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZV2_A_LEVA801_2
(FIBROBLAST GROWTH
FACTOR RECEPTOR 1)		 2glf PROBABLE M18-FAMILY
AMINOPEPTIDASE 1
(Thermotoga
maritima) 		3 / 3 LYS A 180
LEU A 186
ASP A 165
 None
 0.94A 5zv2A-2glfA:
undetectable		 5zv2A-2glfA:
12.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUR_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2glf PROBABLE M18-FAMILY
AMINOPEPTIDASE 1
(Thermotoga
maritima) 		4 / 7 ARG A 261
VAL A 443
PHE A  21
GLU A  17
 None
 1.27A 6aurA-2glfA:
undetectable
6aurB-2glfA:
undetectable		 6aurA-2glfA:
11.98
6aurB-2glfA:
11.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUS_B_H4BB803_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2glf PROBABLE M18-FAMILY
AMINOPEPTIDASE 1
(Thermotoga
maritima) 		4 / 7 PHE A  21
GLU A  17
ARG A 261
VAL A 443
 None
 1.25A 6ausA-2glfA:
undetectable
6ausB-2glfA:
undetectable		 6ausA-2glfA:
11.98
6ausB-2glfA:
11.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUT_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2glf PROBABLE M18-FAMILY
AMINOPEPTIDASE 1
(Thermotoga
maritima) 		4 / 7 PHE A  21
GLU A  17
ARG A 261
VAL A 443
 None
 1.27A 6autA-2glfA:
undetectable
6autB-2glfA:
undetectable		 6autA-2glfA:
11.98
6autB-2glfA:
11.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUX_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2glf PROBABLE M18-FAMILY
AMINOPEPTIDASE 1
(Thermotoga
maritima) 		4 / 7 PHE A  21
GLU A  17
ARG A 261
VAL A 443
 None
 1.27A 6auxA-2glfA:
undetectable
6auxB-2glfA:
undetectable		 6auxA-2glfA:
11.98
6auxB-2glfA:
11.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUY_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2glf PROBABLE M18-FAMILY
AMINOPEPTIDASE 1
(Thermotoga
maritima) 		4 / 7 ARG A 261
VAL A 443
PHE A  21
GLU A  17
 None
 1.23A 6auyA-2glfA:
undetectable
6auyB-2glfA:
undetectable		 6auyA-2glfA:
10.83
6auyB-2glfA:
10.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUZ_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2glf PROBABLE M18-FAMILY
AMINOPEPTIDASE 1
(Thermotoga
maritima) 		4 / 7 ARG A 261
VAL A 443
PHE A  21
GLU A  17
 None
 1.22A 6auzA-2glfA:
undetectable
6auzB-2glfA:
undetectable		 6auzA-2glfA:
10.83
6auzB-2glfA:
10.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AV2_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2glf PROBABLE M18-FAMILY
AMINOPEPTIDASE 1
(Thermotoga
maritima) 		4 / 7 ARG A 261
VAL A 443
PHE A  21
GLU A  17
 None
 1.25A 6av2A-2glfA:
undetectable
6av2B-2glfA:
undetectable		 6av2A-2glfA:
10.83
6av2B-2glfA:
10.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AV3_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2glf PROBABLE M18-FAMILY
AMINOPEPTIDASE 1
(Thermotoga
maritima) 		4 / 7 ARG A 261
VAL A 443
PHE A  21
GLU A  17
 None
 1.26A 6av3A-2glfA:
undetectable
6av3B-2glfA:
undetectable		 6av3A-2glfA:
10.83
6av3B-2glfA:
10.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AV4_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2glf PROBABLE M18-FAMILY
AMINOPEPTIDASE 1
(Thermotoga
maritima) 		4 / 7 ARG A 261
VAL A 443
PHE A  21
GLU A  17
 None
 1.25A 6av4A-2glfA:
undetectable
6av4B-2glfA:
undetectable		 6av4A-2glfA:
10.83
6av4B-2glfA:
10.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AV6_B_H4BB501_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 2glf PROBABLE M18-FAMILY
AMINOPEPTIDASE 1
(Thermotoga
maritima) 		4 / 7 SER A 428
TRP A 129
PHE A 233
GLU A 431
 None
 1.22A 6av6A-2glfA:
0.0
6av6B-2glfA:
undetectable		 6av6A-2glfA:
13.17
6av6B-2glfA:
13.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AV6_D_H4BD502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 2glf PROBABLE M18-FAMILY
AMINOPEPTIDASE 1
(Thermotoga
maritima) 		4 / 7 PHE A 233
GLU A 431
SER A 428
TRP A 129
 None
 1.20A 6av6C-2glfA:
undetectable
6av6D-2glfA:
undetectable		 6av6C-2glfA:
13.17
6av6D-2glfA:
13.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AV7_A_H4BA502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 2glf PROBABLE M18-FAMILY
AMINOPEPTIDASE 1
(Thermotoga
maritima) 		4 / 7 SER A 428
TRP A 129
PHE A 233
GLU A 431
 None
 1.23A 6av7A-2glfA:
undetectable
6av7B-2glfA:
undetectable		 6av7A-2glfA:
13.17
6av7B-2glfA:
13.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DK1_C_GM4C301_0
(SIGMA NON-OPIOID
INTRACELLULAR
RECEPTOR 1)		 2glf PROBABLE M18-FAMILY
AMINOPEPTIDASE 1
(Thermotoga
maritima) 		5 / 11 ALA A  93
LEU A 423
TYR A 445
THR A 258
ALA A 256
 None
 1.15A 6dk1C-2glfA:
undetectable		 6dk1C-2glfA:
21.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MB9_A_NMYA303_0
(AAC(3)-IIIB PROTEIN)		 2glf PROBABLE M18-FAMILY
AMINOPEPTIDASE 1
(Thermotoga
maritima) 		5 / 10 TYR A 295
ASP A 316
THR A 322
GLY A  87
GLU A 317
 None
 1.18A 6mb9A-2glfA:
0.0		 6mb9A-2glfA:
12.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MB9_B_NMYB302_0
(AAC(3)-IIIB PROTEIN)		 2glf PROBABLE M18-FAMILY
AMINOPEPTIDASE 1
(Thermotoga
maritima) 		5 / 10 TYR A 295
ASP A 316
THR A 322
GLY A  87
GLU A 317
 None
 1.25A 6mb9B-2glfA:
0.0		 6mb9B-2glfA:
12.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MB9_D_NMYD302_0
(AAC(3)-IIIB PROTEIN)		 2glf PROBABLE M18-FAMILY
AMINOPEPTIDASE 1
(Thermotoga
maritima) 		5 / 10 TYR A 295
ASP A 316
THR A 322
GLY A  87
GLU A 317
 None
 1.23A 6mb9D-2glfA:
0.0		 6mb9D-2glfA:
12.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MN5_C_LLLC301_0
(AMINOGLYCOSIDE
N(3)-ACETYLTRANSFERA
SE, AAC(3)-IVA)		 2glf PROBABLE M18-FAMILY
AMINOPEPTIDASE 1
(Thermotoga
maritima) 		4 / 6 ASP A 101
GLU A  35
ASP A  96
GLU A 280
 None
None
None
MN  A5001 (-4.4A)
 1.35A 6mn5C-2glfA:
undetectable		 6mn5C-2glfA:
8.99