SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2glx'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1AV2_B_DVAB8_0
(GRAMICIDIN A)		 2glx 1,5-ANHYDRO-D-FRUCTO
SE REDUCTASE
(Ensifer
adhaerens) 		3 / 3 VAL A  28
VAL A  64
TRP A   4
 None
 0.89A 1av2A-2glxA:
undetectable
1av2B-2glxA:
undetectable		 1av2A-2glxA:
4.42
1av2B-2glxA:
4.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DFO_A_FFOA1002_0
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 2glx 1,5-ANHYDRO-D-FRUCTO
SE REDUCTASE
(Ensifer
adhaerens) 		5 / 12 LEU A  91
LEU A 287
SER A 301
ALA A 302
SER A  70
 None
 1.01A 1dfoA-2glxA:
undetectable		 1dfoA-2glxA:
22.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DFO_B_FFOB2002_1
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 2glx 1,5-ANHYDRO-D-FRUCTO
SE REDUCTASE
(Ensifer
adhaerens) 		5 / 12 LEU A  91
LEU A 287
SER A 301
ALA A 302
SER A  70
 None
 1.01A 1dfoB-2glxA:
undetectable		 1dfoB-2glxA:
22.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DFO_C_FFOC3002_1
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 2glx 1,5-ANHYDRO-D-FRUCTO
SE REDUCTASE
(Ensifer
adhaerens) 		5 / 12 LEU A  91
LEU A 287
SER A 301
ALA A 302
SER A  70
 None
 1.00A 1dfoC-2glxA:
1.8		 1dfoC-2glxA:
22.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DFO_D_FFOD4002_1
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 2glx 1,5-ANHYDRO-D-FRUCTO
SE REDUCTASE
(Ensifer
adhaerens) 		5 / 12 LEU A  91
LEU A 287
SER A 301
ALA A 302
SER A  70
 None
 1.00A 1dfoD-2glxA:
undetectable		 1dfoD-2glxA:
22.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EPB_A_9CRA165_2
(EPIDIDYMAL RETINOIC
ACID-BINDING PROTEIN)		 2glx 1,5-ANHYDRO-D-FRUCTO
SE REDUCTASE
(Ensifer
adhaerens) 		4 / 7 LEU A 218
ALA A 226
PHE A 228
VAL A 149
 None
 0.90A 1epbA-2glxA:
undetectable		 1epbA-2glxA:
20.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EQB_A_FFOA1293_0
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 2glx 1,5-ANHYDRO-D-FRUCTO
SE REDUCTASE
(Ensifer
adhaerens) 		5 / 12 LEU A  91
LEU A 287
SER A 301
ALA A 302
SER A  70
 None
 1.05A 1eqbA-2glxA:
1.6		 1eqbA-2glxA:
22.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EQB_B_FFOB2293_1
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 2glx 1,5-ANHYDRO-D-FRUCTO
SE REDUCTASE
(Ensifer
adhaerens) 		5 / 12 LEU A  91
LEU A 287
SER A 301
ALA A 302
SER A  70
 None
 1.05A 1eqbB-2glxA:
undetectable		 1eqbB-2glxA:
22.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EQB_C_FFOC3293_1
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 2glx 1,5-ANHYDRO-D-FRUCTO
SE REDUCTASE
(Ensifer
adhaerens) 		5 / 12 LEU A  91
LEU A 287
SER A 301
ALA A 302
SER A  70
 None
 1.04A 1eqbC-2glxA:
1.8		 1eqbC-2glxA:
22.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EQB_D_FFOD4293_1
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 2glx 1,5-ANHYDRO-D-FRUCTO
SE REDUCTASE
(Ensifer
adhaerens) 		5 / 12 LEU A  91
LEU A 287
SER A 301
ALA A 302
SER A  70
 None
 1.04A 1eqbD-2glxA:
1.8		 1eqbD-2glxA:
22.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HRK_B_CHDB2503_0
(FERROCHELATASE)		 2glx 1,5-ANHYDRO-D-FRUCTO
SE REDUCTASE
(Ensifer
adhaerens) 		4 / 4 LEU A  96
PRO A  95
LEU A 311
ARG A 104
 None
 1.36A 1hrkB-2glxA:
2.1		 1hrkB-2glxA:
23.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HRC_B_CHDB1604_0
(FERROCHELATASE)		 2glx 1,5-ANHYDRO-D-FRUCTO
SE REDUCTASE
(Ensifer
adhaerens) 		4 / 4 LEU A  96
PRO A  95
LEU A 311
ARG A 104
 None
 1.31A 2hrcB-2glxA:
2.1		 2hrcB-2glxA:
23.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PNJ_B_CHDB503_0
(FERROCHELATASE,
MITOCHONDRIAL)		 2glx 1,5-ANHYDRO-D-FRUCTO
SE REDUCTASE
(Ensifer
adhaerens) 		4 / 4 LEU A  96
PRO A  95
LEU A 311
ARG A 104
 None
 1.43A 2pnjB-2glxA:
2.2		 2pnjB-2glxA:
23.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2R5Q_B_1UNB900_1
(PROTEASE)		 2glx 1,5-ANHYDRO-D-FRUCTO
SE REDUCTASE
(Ensifer
adhaerens) 		5 / 9 LEU A 287
ILE A  48
ILE A   7
VAL A  17
ILE A  21
 None
 1.08A 2r5qA-2glxA:
undetectable		 2r5qA-2glxA:
15.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2R5Q_D_1UND900_1
(PROTEASE)		 2glx 1,5-ANHYDRO-D-FRUCTO
SE REDUCTASE
(Ensifer
adhaerens) 		5 / 9 LEU A 287
ILE A  48
ILE A   7
VAL A  17
ILE A  21
 None
 1.08A 2r5qC-2glxA:
undetectable		 2r5qC-2glxA:
15.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VMY_A_FFOA505_1
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 2glx 1,5-ANHYDRO-D-FRUCTO
SE REDUCTASE
(Ensifer
adhaerens) 		5 / 12 LEU A  91
LEU A 287
SER A 301
ALA A 302
SER A  70
 None
 0.91A 2vmyB-2glxA:
undetectable		 2vmyB-2glxA:
22.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VMY_B_FFOB505_0
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 2glx 1,5-ANHYDRO-D-FRUCTO
SE REDUCTASE
(Ensifer
adhaerens) 		5 / 12 LEU A  91
LEU A 287
SER A 301
ALA A 302
SER A  70
 None
 0.87A 2vmyA-2glxA:
undetectable		 2vmyA-2glxA:
22.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XRZ_A_ACTA1470_0
(DEOXYRIBODIPYRIMIDIN
E PHOTOLYASE)		 2glx 1,5-ANHYDRO-D-FRUCTO
SE REDUCTASE
(Ensifer
adhaerens) 		4 / 5 ARG A 140
ALA A 135
ASP A 134
GLU A 138
 None
 1.02A 2xrzA-2glxA:
1.3		 2xrzA-2glxA:
20.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D91_A_REMA350_1
(RENIN)		 2glx 1,5-ANHYDRO-D-FRUCTO
SE REDUCTASE
(Ensifer
adhaerens) 		5 / 12 GLN A 258
ASP A 230
THR A 239
ASP A 181
HIS A 129
 ACT  A1502 ( 4.1A)
None
None
None
None
 1.27A 3d91A-2glxA:
undetectable		 3d91A-2glxA:
21.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FW3_B_ETSB303_1
(CARBONIC ANHYDRASE 4)		 2glx 1,5-ANHYDRO-D-FRUCTO
SE REDUCTASE
(Ensifer
adhaerens) 		5 / 12 HIS A 201
ILE A 177
VAL A 173
THR A 233
THR A 234
 None
 1.06A 3fw3B-2glxA:
undetectable		 3fw3B-2glxA:
22.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QJ7_A_SPMA264_1
(THYMIDYLATE SYNTHASE)		 2glx 1,5-ANHYDRO-D-FRUCTO
SE REDUCTASE
(Ensifer
adhaerens) 		4 / 8 ALA A 226
LEU A 185
ASP A 191
SER A 222
 None
 0.96A 3qj7A-2glxA:
undetectable
3qj7D-2glxA:
undetectable		 3qj7A-2glxA:
23.38
3qj7D-2glxA:
23.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ZQT_A_30ZA1920_1
(ANDROGEN RECEPTOR)		 2glx 1,5-ANHYDRO-D-FRUCTO
SE REDUCTASE
(Ensifer
adhaerens) 		4 / 6 PRO A 167
GLY A 170
ASN A  73
LEU A 175
 None
None
NDP  A1500 (-3.4A)
None
 1.00A 3zqtA-2glxA:
undetectable		 3zqtA-2glxA:
18.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4BVA_A_T3A1314_1
(THIOMORPHOLINE-CARBO
XYLATE DEHYDROGENASE)		 2glx 1,5-ANHYDRO-D-FRUCTO
SE REDUCTASE
(Ensifer
adhaerens) 		5 / 12 VAL A 317
GLY A 314
VAL A 179
HIS A 151
GLU A 211
 None
 1.35A 4bvaA-2glxA:
8.7		 4bvaA-2glxA:
22.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4I41_A_MIXA501_1
(SERINE/THREONINE-PRO
TEIN KINASE PIM-1)		 2glx 1,5-ANHYDRO-D-FRUCTO
SE REDUCTASE
(Ensifer
adhaerens) 		5 / 12 ASP A 181
THR A 239
VAL A 153
ASP A 176
ILE A 177
 None
None
None
ACT  A1502 ( 3.9A)
None
 1.29A 4i41A-2glxA:
undetectable		 4i41A-2glxA:
20.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R29_B_SAMB301_0
(UNCHARACTERIZED
PROTEIN)		 2glx 1,5-ANHYDRO-D-FRUCTO
SE REDUCTASE
(Ensifer
adhaerens) 		5 / 12 ALA A  13
SER A  10
GLY A   8
ALA A  66
GLY A   5
 None
NDP  A1500 (-4.0A)
NDP  A1500 (-3.0A)
None
None
 1.12A 4r29B-2glxA:
undetectable		 4r29B-2glxA:
18.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RET_C_DGXC2005_1
(SODIUM/POTASSIUM-TRA
NSPORTING ATPASE
SUBUNIT ALPHA-1)		 2glx 1,5-ANHYDRO-D-FRUCTO
SE REDUCTASE
(Ensifer
adhaerens) 		5 / 12 GLU A 330
LEU A 218
GLY A 314
ALA A 182
ARG A 104
 None
 1.21A 4retC-2glxA:
5.1		 4retC-2glxA:
16.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XNX_A_41XA707_1
(TRANSPORTER)		 2glx 1,5-ANHYDRO-D-FRUCTO
SE REDUCTASE
(Ensifer
adhaerens) 		5 / 11 ALA A 231
VAL A 173
ASP A 212
GLY A 216
SER A 200
 None
 1.23A 4xnxA-2glxA:
undetectable		 4xnxA-2glxA:
22.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z2E_F_TR6F101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT B
SYMMETRIZED E-SITE
DNA)		 2glx 1,5-ANHYDRO-D-FRUCTO
SE REDUCTASE
(Ensifer
adhaerens) 		4 / 5 GLY A 252
ARG A 253
GLY A 240
GLU A 238
 None
 1.20A 4z2eB-2glxA:
undetectable
4z2eC-2glxA:
2.1		 4z2eB-2glxA:
20.67
4z2eC-2glxA:
21.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A06_A_SORA1341_0
(ALDOSE-ALDOSE
OXIDOREDUCTASE)		 2glx 1,5-ANHYDRO-D-FRUCTO
SE REDUCTASE
(Ensifer
adhaerens) 		4 / 7 LYS A  94
PHE A 232
ARG A 163
ASP A 176
 NDP  A1500 ( 2.9A)
None
NDP  A1500 (-3.0A)
ACT  A1502 ( 3.9A)
 1.24A 5a06A-2glxA:
38.9		 5a06A-2glxA:
29.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A06_A_SORA1343_0
(ALDOSE-ALDOSE
OXIDOREDUCTASE)		 2glx 1,5-ANHYDRO-D-FRUCTO
SE REDUCTASE
(Ensifer
adhaerens) 		4 / 6 ASP A  65
LYS A  88
HIS A  89
ILE A 294
 None
 0.74A 5a06A-2glxA:
38.9		 5a06A-2glxA:
29.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A06_B_SORB1341_0
(ALDOSE-ALDOSE
OXIDOREDUCTASE)		 2glx 1,5-ANHYDRO-D-FRUCTO
SE REDUCTASE
(Ensifer
adhaerens) 		5 / 7 LYS A  94
PHE A 232
ARG A 163
ASP A 176
ILE A 177
 NDP  A1500 ( 2.9A)
None
NDP  A1500 (-3.0A)
ACT  A1502 ( 3.9A)
None
 1.34A 5a06B-2glxA:
39.0		 5a06B-2glxA:
29.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A06_B_SORB1343_0
(ALDOSE-ALDOSE
OXIDOREDUCTASE)		 2glx 1,5-ANHYDRO-D-FRUCTO
SE REDUCTASE
(Ensifer
adhaerens) 		4 / 5 ASP A  65
LYS A  88
HIS A  89
ILE A 294
 None
 0.79A 5a06B-2glxA:
39.0		 5a06B-2glxA:
29.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A06_C_SORC1341_0
(ALDOSE-ALDOSE
OXIDOREDUCTASE)		 2glx 1,5-ANHYDRO-D-FRUCTO
SE REDUCTASE
(Ensifer
adhaerens) 		4 / 7 LYS A  94
PHE A 232
ARG A 163
ASP A 176
 NDP  A1500 ( 2.9A)
None
NDP  A1500 (-3.0A)
ACT  A1502 ( 3.9A)
 1.24A 5a06C-2glxA:
38.9		 5a06C-2glxA:
29.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A06_D_SORD1342_0
(ALDOSE-ALDOSE
OXIDOREDUCTASE)		 2glx 1,5-ANHYDRO-D-FRUCTO
SE REDUCTASE
(Ensifer
adhaerens) 		4 / 7 LYS A  94
PHE A 232
ARG A 163
ASP A 176
 NDP  A1500 ( 2.9A)
None
NDP  A1500 (-3.0A)
ACT  A1502 ( 3.9A)
 1.22A 5a06D-2glxA:
39.0		 5a06D-2glxA:
29.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A06_D_SORD1344_0
(ALDOSE-ALDOSE
OXIDOREDUCTASE)		 2glx 1,5-ANHYDRO-D-FRUCTO
SE REDUCTASE
(Ensifer
adhaerens) 		4 / 5 ASP A  65
LYS A  88
HIS A  89
ILE A 294
 None
 0.75A 5a06D-2glxA:
39.0		 5a06D-2glxA:
29.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A06_E_SORE1342_0
(ALDOSE-ALDOSE
OXIDOREDUCTASE)		 2glx 1,5-ANHYDRO-D-FRUCTO
SE REDUCTASE
(Ensifer
adhaerens) 		4 / 7 LYS A  94
PHE A 232
ARG A 163
ASP A 176
 NDP  A1500 ( 2.9A)
None
NDP  A1500 (-3.0A)
ACT  A1502 ( 3.9A)
 1.24A 5a06E-2glxA:
39.1		 5a06E-2glxA:
29.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A06_F_SORF1343_0
(ALDOSE-ALDOSE
OXIDOREDUCTASE)		 2glx 1,5-ANHYDRO-D-FRUCTO
SE REDUCTASE
(Ensifer
adhaerens) 		4 / 7 LYS A  94
PHE A 232
ARG A 163
ASP A 176
 NDP  A1500 ( 2.9A)
None
NDP  A1500 (-3.0A)
ACT  A1502 ( 3.9A)
 1.23A 5a06F-2glxA:
39.0		 5a06F-2glxA:
29.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A06_F_SORF1344_0
(ALDOSE-ALDOSE
OXIDOREDUCTASE)		 2glx 1,5-ANHYDRO-D-FRUCTO
SE REDUCTASE
(Ensifer
adhaerens) 		4 / 5 ASP A  65
LYS A  88
HIS A  89
ILE A 294
 None
 0.77A 5a06F-2glxA:
39.0		 5a06F-2glxA:
29.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BS8_G_MFXG101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT B
DNA SUBSTRATE 24-MER
TTACGTGCATAGTCATTCAT
GACC)		 2glx 1,5-ANHYDRO-D-FRUCTO
SE REDUCTASE
(Ensifer
adhaerens) 		4 / 7 ALA A 286
ARG A  22
GLY A  26
GLU A  27
 None
 0.76A 5bs8A-2glxA:
undetectable
5bs8C-2glxA:
undetectable
5bs8D-2glxA:
1.8		 5bs8A-2glxA:
24.04
5bs8C-2glxA:
24.04
5bs8D-2glxA:
23.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BTG_E_LFXE101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT B
DNA SUBSTRATE 24-MER
GGTCATGAATGACTATGCAC
GTAA)		 2glx 1,5-ANHYDRO-D-FRUCTO
SE REDUCTASE
(Ensifer
adhaerens) 		4 / 6 ALA A 286
ARG A  22
GLY A  26
GLU A  27
 None
 0.71A 5btgA-2glxA:
undetectable
5btgB-2glxA:
2.1
5btgC-2glxA:
undetectable		 5btgA-2glxA:
24.04
5btgB-2glxA:
23.30
5btgC-2glxA:
24.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BTG_F_LFXF101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT B
DNA SUBSTRATE 24-MER
TTACGTGCATAGTCATTCAT
GACC)		 2glx 1,5-ANHYDRO-D-FRUCTO
SE REDUCTASE
(Ensifer
adhaerens) 		4 / 7 ALA A 286
ARG A  22
GLY A  26
GLU A  27
 None
 0.82A 5btgA-2glxA:
undetectable
5btgC-2glxA:
undetectable
5btgD-2glxA:
1.8		 5btgA-2glxA:
24.04
5btgC-2glxA:
24.04
5btgD-2glxA:
23.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HWA_A_GCSA301_1
(CHITOSANASE)		 2glx 1,5-ANHYDRO-D-FRUCTO
SE REDUCTASE
(Ensifer
adhaerens) 		4 / 8 ILE A 177
ARG A 163
GLY A 172
ASN A  73
 None
NDP  A1500 (-3.0A)
None
NDP  A1500 (-3.4A)
 1.06A 5hwaA-2glxA:
undetectable		 5hwaA-2glxA:
19.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L6E_A_SAMA601_0
(N6-ADENOSINE-METHYLT
RANSFERASE 70 KDA
SUBUNIT)		 2glx 1,5-ANHYDRO-D-FRUCTO
SE REDUCTASE
(Ensifer
adhaerens) 		5 / 12 LEU A 185
SER A 249
PHE A 241
GLY A 252
GLY A 240
 None
 1.07A 5l6eA-2glxA:
undetectable		 5l6eA-2glxA:
22.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EMU_B_SAMB301_0
(TRNA
(GUANINE(9)-/ADENINE
(9)-N1)-METHYLTRANSF
ERASE)		 2glx 1,5-ANHYDRO-D-FRUCTO
SE REDUCTASE
(Ensifer
adhaerens) 		5 / 12 LEU A 250
ILE A 141
GLY A 245
ILE A 145
ILE A 136
 None
 1.07A 6emuB-2glxA:
2.9		 6emuB-2glxA:
18.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6F7L_B_ACTB505_0
(AMINE OXIDASE LKCE)		 2glx 1,5-ANHYDRO-D-FRUCTO
SE REDUCTASE
(Ensifer
adhaerens) 		3 / 3 HIS A  76
ASN A  73
LEU A 175
 NDP  A1500 (-4.1A)
NDP  A1500 (-3.4A)
None
 0.74A 6f7lB-2glxA:
undetectable		 6f7lB-2glxA:
21.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NQA_K_SAMK500_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE,
H3 LYSINE-79
SPECIFIC)		 2glx 1,5-ANHYDRO-D-FRUCTO
SE REDUCTASE
(Ensifer
adhaerens) 		5 / 10 THR A 257
GLY A 252
GLY A 240
GLU A 242
ASN A 254
 None
 1.20A 6nqaK-2glxA:
undetectable		 6nqaK-2glxA:
22.25