SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2gm5'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FBM_B_RTLB951_3
(PROTEIN (CARTILAGE
OLIGOMERIC MATRIX
PROTEIN))		 2gm5 TRANSPOSON
GAMMA-DELTA
RESOLVASE
(Escherichia
coli) 		4 / 5 LEU A  23
VAL A  20
LEU A  16
GLN A  13
 None
 0.88A 1fbmE-2gm5A:
undetectable		 1fbmE-2gm5A:
25.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2E5D_A_NCAA1501_0
(NICOTINAMIDE
PHOSPHORIBOSYLTRANSF
ERASE)		 2gm5 TRANSPOSON
GAMMA-DELTA
RESOLVASE
(Escherichia
coli) 		4 / 7 ARG A  71
ASP A  36
ARG A  52
ASP A  44
 None
 1.18A 2e5dA-2gm5A:
undetectable
2e5dB-2gm5A:
undetectable		 2e5dA-2gm5A:
15.26
2e5dB-2gm5A:
15.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2E5D_B_NCAB1502_0
(NICOTINAMIDE
PHOSPHORIBOSYLTRANSF
ERASE)		 2gm5 TRANSPOSON
GAMMA-DELTA
RESOLVASE
(Escherichia
coli) 		4 / 7 ASP A  44
ARG A  71
ASP A  36
ARG A  52
 None
 1.18A 2e5dA-2gm5A:
undetectable
2e5dB-2gm5A:
undetectable		 2e5dA-2gm5A:
15.26
2e5dB-2gm5A:
15.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NUJ_B_478B401_1
(PROTEASE)		 2gm5 TRANSPOSON
GAMMA-DELTA
RESOLVASE
(Escherichia
coli) 		5 / 10 ALA A  26
ASP A  25
GLY A   5
ILE A  61
ILE A  93
 None
 1.00A 3nujA-2gm5A:
undetectable		 3nujA-2gm5A:
23.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NUO_B_478B478_1
(PROTEASE)		 2gm5 TRANSPOSON
GAMMA-DELTA
RESOLVASE
(Escherichia
coli) 		5 / 9 ALA A  26
ASP A  25
GLY A   5
ILE A  61
ILE A  93
 None
 1.04A 3nuoA-2gm5A:
undetectable		 3nuoA-2gm5A:
23.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JW1_B_CELB602_2
(PROSTAGLANDIN G/H
SYNTHASE 2)		 2gm5 TRANSPOSON
GAMMA-DELTA
RESOLVASE
(Escherichia
coli) 		4 / 6 VAL A 107
ARG A  91
ILE A  90
PHE A  92
 None
 0.95A 5jw1B-2gm5A:
undetectable		 5jw1B-2gm5A:
13.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KR0_A_478A101_1
(PROTEASE E35D-APV)		 2gm5 TRANSPOSON
GAMMA-DELTA
RESOLVASE
(Escherichia
coli) 		5 / 9 ALA A  26
ASP A  25
GLY A   5
ILE A  61
ILE A  93
 None
 0.96A 5kr0A-2gm5A:
undetectable		 5kr0A-2gm5A:
23.40