SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2gmh'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID
Hit
Macromolecule
Res.
Matches
Interface HETATM RMSD Dali
Z-score
Seq.
Identity (%)
View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1BX4_A_ADNA355_1
(PROTEIN (ADENOSINE
KINASE))
2gmh ELECTRON TRANSFER
FLAVOPROTEIN-UBIQUIN
ONE OXIDOREDUCTASE

(Sus
scrofa)
5 / 12 GLY A 164
ALA A  43
GLY A  42
HIS A  79
ILE A  76
None
None
FAD  A 611 (-3.3A)
FAD  A 611 (-4.4A)
None
0.94A 1bx4A-2gmhA:
4.5
1bx4A-2gmhA:
18.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C8L_A_CFFA940_1
(PROTEIN (GLYCOGEN
PHOSPHORYLASE))
2gmh ELECTRON TRANSFER
FLAVOPROTEIN-UBIQUIN
ONE OXIDOREDUCTASE

(Sus
scrofa)
4 / 6 HIS A 216
ALA A 332
GLY A 239
TYR A 238
None
0.93A 1c8lA-2gmhA:
undetectable
1c8lA-2gmhA:
21.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1CLA_A_CLMA221_0
(TYPE III
CHLORAMPHENICOL
ACETYLTRANSFERASE)
2gmh ELECTRON TRANSFER
FLAVOPROTEIN-UBIQUIN
ONE OXIDOREDUCTASE

(Sus
scrofa)
5 / 10 ALA A 370
ALA A 212
LEU A  69
VAL A 159
ILE A  40
FAD  A 611 ( 4.0A)
None
None
None
None
1.33A 1claA-2gmhA:
undetectable
1claA-2gmhA:
17.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EPB_B_9CRB165_2
(EPIDIDYMAL RETINOIC
ACID-BINDING PROTEIN)
2gmh ELECTRON TRANSFER
FLAVOPROTEIN-UBIQUIN
ONE OXIDOREDUCTASE

(Sus
scrofa)
4 / 8 LEU A 223
ALA A 220
PHE A 211
TYR A 402
None
0.87A 1epbB-2gmhA:
1.7
1epbB-2gmhA:
15.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GFZ_A_CFFA940_1
(GLYCOGEN
PHOSPHORYLASE)
2gmh ELECTRON TRANSFER
FLAVOPROTEIN-UBIQUIN
ONE OXIDOREDUCTASE

(Sus
scrofa)
4 / 6 HIS A 216
ALA A 332
GLY A 239
TYR A 238
None
0.96A 1gfzA-2gmhA:
2.6
1gfzA-2gmhA:
21.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_N_TRPN81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))
2gmh ELECTRON TRANSFER
FLAVOPROTEIN-UBIQUIN
ONE OXIDOREDUCTASE

(Sus
scrofa)
4 / 8 GLY A 577
HIS A 496
ALA A 580
SER A 492
EDO  A 619 (-3.2A)
None
EDO  A 624 (-3.5A)
EDO  A 621 ( 4.6A)
0.83A 1gtfN-2gmhA:
undetectable
1gtfO-2gmhA:
undetectable
1gtfN-2gmhA:
8.82
1gtfO-2gmhA:
8.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1IBG_H_OBNH1_1
(IGG2B-KAPPA 40-50
FAB (HEAVY CHAIN))
2gmh ELECTRON TRANSFER
FLAVOPROTEIN-UBIQUIN
ONE OXIDOREDUCTASE

(Sus
scrofa)
4 / 6 LEU A 223
PHE A 346
TYR A 402
VAL A 178
None
1.25A 1ibgH-2gmhA:
undetectable
1ibgH-2gmhA:
15.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L5Q_A_CFFA863_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)
2gmh ELECTRON TRANSFER
FLAVOPROTEIN-UBIQUIN
ONE OXIDOREDUCTASE

(Sus
scrofa)
4 / 6 HIS A 216
ALA A 332
GLY A 239
TYR A 238
None
1.03A 1l5qA-2gmhA:
3.1
1l5qA-2gmhA:
21.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L5Q_B_CFFB1863_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)
2gmh ELECTRON TRANSFER
FLAVOPROTEIN-UBIQUIN
ONE OXIDOREDUCTASE

(Sus
scrofa)
4 / 6 HIS A 216
ALA A 332
GLY A 239
TYR A 238
None
1.03A 1l5qB-2gmhA:
undetectable
1l5qB-2gmhA:
21.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L7X_A_CFFA863_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)
2gmh ELECTRON TRANSFER
FLAVOPROTEIN-UBIQUIN
ONE OXIDOREDUCTASE

(Sus
scrofa)
4 / 6 HIS A 216
ALA A 332
GLY A 239
TYR A 238
None
1.06A 1l7xA-2gmhA:
undetectable
1l7xA-2gmhA:
21.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L7X_B_CFFB1863_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)
2gmh ELECTRON TRANSFER
FLAVOPROTEIN-UBIQUIN
ONE OXIDOREDUCTASE

(Sus
scrofa)
4 / 6 HIS A 216
ALA A 332
GLY A 239
TYR A 238
None
1.06A 1l7xB-2gmhA:
undetectable
1l7xB-2gmhA:
21.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LQT_A_ACTA1871_0
(FPRA)
2gmh ELECTRON TRANSFER
FLAVOPROTEIN-UBIQUIN
ONE OXIDOREDUCTASE

(Sus
scrofa)
4 / 7 PRO A 356
ALA A  46
PHE A 358
SER A 373
None
FAD  A 611 (-3.2A)
None
None
1.19A 1lqtA-2gmhA:
10.6
1lqtA-2gmhA:
21.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LQU_A_ACTA1428_0
(FPRA)
2gmh ELECTRON TRANSFER
FLAVOPROTEIN-UBIQUIN
ONE OXIDOREDUCTASE

(Sus
scrofa)
4 / 7 PRO A 356
ALA A  46
PHE A 358
SER A 373
None
FAD  A 611 (-3.2A)
None
None
1.18A 1lquA-2gmhA:
10.6
1lquA-2gmhA:
21.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RJD_A_SAMA801_0
(CARBOXY METHYL
TRANSFERASE FOR
PROTEIN PHOSPHATASE
2A CATALYTIC SUBUNIT)
2gmh ELECTRON TRANSFER
FLAVOPROTEIN-UBIQUIN
ONE OXIDOREDUCTASE

(Sus
scrofa)
5 / 12 ALA A  90
GLY A  47
GLY A 374
LEU A  69
LEU A  48
None
1.10A 1rjdA-2gmhA:
undetectable
1rjdA-2gmhA:
18.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RJD_C_SAMC803_0
(CARBOXY METHYL
TRANSFERASE FOR
PROTEIN PHOSPHATASE
2A CATALYTIC SUBUNIT)
2gmh ELECTRON TRANSFER
FLAVOPROTEIN-UBIQUIN
ONE OXIDOREDUCTASE

(Sus
scrofa)
5 / 12 ALA A  90
GLY A  47
GLY A 374
LEU A  69
LEU A  48
None
1.10A 1rjdC-2gmhA:
undetectable
1rjdC-2gmhA:
18.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RMT_D_ADND1504_1
(CLASS B ACID
PHOSPHATASE)
2gmh ELECTRON TRANSFER
FLAVOPROTEIN-UBIQUIN
ONE OXIDOREDUCTASE

(Sus
scrofa)
4 / 8 ASP A 563
TYR A 296
ASP A 461
THR A 558
None
None
None
SF4  A 610 ( 4.5A)
1.07A 1rmtD-2gmhA:
undetectable
1rmtD-2gmhA:
17.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RXC_B_URFB2011_1
(URIDINE
PHOSPHORYLASE)
2gmh ELECTRON TRANSFER
FLAVOPROTEIN-UBIQUIN
ONE OXIDOREDUCTASE

(Sus
scrofa)
4 / 8 GLY A 293
ILE A 240
VAL A 292
PRO A 303
None
0.88A 1rxcB-2gmhA:
undetectable
1rxcB-2gmhA:
19.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RXC_C_URFC2081_1
(URIDINE
PHOSPHORYLASE)
2gmh ELECTRON TRANSFER
FLAVOPROTEIN-UBIQUIN
ONE OXIDOREDUCTASE

(Sus
scrofa)
4 / 7 GLY A 293
ILE A 240
VAL A 292
PRO A 303
None
0.99A 1rxcC-2gmhA:
undetectable
1rxcC-2gmhA:
19.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RXC_D_URFD2021_1
(URIDINE
PHOSPHORYLASE)
2gmh ELECTRON TRANSFER
FLAVOPROTEIN-UBIQUIN
ONE OXIDOREDUCTASE

(Sus
scrofa)
4 / 7 GLY A 293
ILE A 240
VAL A 292
PRO A 303
None
1.00A 1rxcD-2gmhA:
undetectable
1rxcD-2gmhA:
19.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RXC_E_URFE2031_1
(URIDINE
PHOSPHORYLASE)
2gmh ELECTRON TRANSFER
FLAVOPROTEIN-UBIQUIN
ONE OXIDOREDUCTASE

(Sus
scrofa)
4 / 8 GLY A 293
ILE A 240
VAL A 292
PRO A 303
None
0.93A 1rxcE-2gmhA:
undetectable
1rxcE-2gmhA:
19.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RXC_E_URFE2031_1
(URIDINE
PHOSPHORYLASE)
2gmh ELECTRON TRANSFER
FLAVOPROTEIN-UBIQUIN
ONE OXIDOREDUCTASE

(Sus
scrofa)
4 / 8 THR A 438
ILE A 421
VAL A 418
PRO A 362
UQ5  A 612 (-3.0A)
None
None
None
0.99A 1rxcE-2gmhA:
undetectable
1rxcE-2gmhA:
19.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RXC_F_URFF2001_1
(URIDINE
PHOSPHORYLASE)
2gmh ELECTRON TRANSFER
FLAVOPROTEIN-UBIQUIN
ONE OXIDOREDUCTASE

(Sus
scrofa)
4 / 7 GLY A 293
ILE A 240
VAL A 292
PRO A 303
None
0.94A 1rxcF-2gmhA:
undetectable
1rxcF-2gmhA:
19.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RXC_I_URFI2041_1
(URIDINE
PHOSPHORYLASE)
2gmh ELECTRON TRANSFER
FLAVOPROTEIN-UBIQUIN
ONE OXIDOREDUCTASE

(Sus
scrofa)
4 / 8 GLY A 293
ILE A 240
VAL A 292
PRO A 303
None
0.89A 1rxcI-2gmhA:
undetectable
1rxcI-2gmhA:
19.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RXC_I_URFI2041_1
(URIDINE
PHOSPHORYLASE)
2gmh ELECTRON TRANSFER
FLAVOPROTEIN-UBIQUIN
ONE OXIDOREDUCTASE

(Sus
scrofa)
4 / 8 THR A 438
ILE A 421
VAL A 418
PRO A 362
UQ5  A 612 (-3.0A)
None
None
None
0.97A 1rxcI-2gmhA:
undetectable
1rxcI-2gmhA:
19.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RXC_K_URFK2061_1
(URIDINE
PHOSPHORYLASE)
2gmh ELECTRON TRANSFER
FLAVOPROTEIN-UBIQUIN
ONE OXIDOREDUCTASE

(Sus
scrofa)
4 / 8 GLY A 293
ILE A 240
VAL A 292
PRO A 303
None
0.88A 1rxcK-2gmhA:
undetectable
1rxcK-2gmhA:
19.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RXC_L_URFL2071_1
(URIDINE
PHOSPHORYLASE)
2gmh ELECTRON TRANSFER
FLAVOPROTEIN-UBIQUIN
ONE OXIDOREDUCTASE

(Sus
scrofa)
4 / 7 GLY A 293
ILE A 240
VAL A 292
PRO A 303
None
0.91A 1rxcL-2gmhA:
undetectable
1rxcL-2gmhA:
19.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WG8_B_SAMB3141_1
(PREDICTED
S-ADENOSYLMETHIONINE
-DEPENDENT
METHYLTRANSFERASE)
2gmh ELECTRON TRANSFER
FLAVOPROTEIN-UBIQUIN
ONE OXIDOREDUCTASE

(Sus
scrofa)
3 / 3 HIS A 555
ASP A 560
ASN A 567
None
0.85A 1wg8B-2gmhA:
3.5
1wg8B-2gmhA:
18.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2CBR_A_A80A201_1
(PROTEIN (CRABP-I))
2gmh ELECTRON TRANSFER
FLAVOPROTEIN-UBIQUIN
ONE OXIDOREDUCTASE

(Sus
scrofa)
5 / 12 LEU A 333
THR A 369
GLY A 336
LEU A 344
TYR A 402
FAD  A 611 ( 4.0A)
None
None
None
None
0.99A 2cbrA-2gmhA:
undetectable
2cbrA-2gmhA:
12.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2CC8_A_RBFA1067_1
(VNG1446H)
2gmh ELECTRON TRANSFER
FLAVOPROTEIN-UBIQUIN
ONE OXIDOREDUCTASE

(Sus
scrofa)
3 / 3 PHE A 198
VAL A  27
TRP A  24
None
0.84A 2cc8A-2gmhA:
undetectable
2cc8A-2gmhA:
7.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2CCB_A_RBFA1067_1
(VNG1446H)
2gmh ELECTRON TRANSFER
FLAVOPROTEIN-UBIQUIN
ONE OXIDOREDUCTASE

(Sus
scrofa)
3 / 3 PHE A 198
VAL A  27
TRP A  24
None
0.83A 2ccbA-2gmhA:
undetectable
2ccbA-2gmhA:
7.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F80_B_017B301_1
(POL POLYPROTEIN)
2gmh ELECTRON TRANSFER
FLAVOPROTEIN-UBIQUIN
ONE OXIDOREDUCTASE

(Sus
scrofa)
5 / 12 LEU A 350
GLY A 374
ALA A  50
VAL A 208
ILE A 210
None
1.03A 2f80A-2gmhA:
undetectable
2f80A-2gmhA:
11.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F8G_B_017B401_1
(POL POLYPROTEIN)
2gmh ELECTRON TRANSFER
FLAVOPROTEIN-UBIQUIN
ONE OXIDOREDUCTASE

(Sus
scrofa)
5 / 12 LEU A 350
GLY A 374
ALA A  50
VAL A 208
ILE A 210
None
1.07A 2f8gA-2gmhA:
undetectable
2f8gA-2gmhA:
10.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2J9C_C_ACTC1120_0
(HYPOTHETICAL
NITROGEN REGULATORY
PII-LIKE PROTEIN
MJ0059)
2gmh ELECTRON TRANSFER
FLAVOPROTEIN-UBIQUIN
ONE OXIDOREDUCTASE

(Sus
scrofa)
3 / 3 LYS A 467
TYR A 520
PRO A 465
None
0.97A 2j9cC-2gmhA:
1.9
2j9cC-2gmhA:
11.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QHF_A_NCAA493_0
(CHORISMATE SYNTHASE)
2gmh ELECTRON TRANSFER
FLAVOPROTEIN-UBIQUIN
ONE OXIDOREDUCTASE

(Sus
scrofa)
5 / 11 ALA A  50
ILE A 381
ILE A 352
ALA A 212
VAL A  38
None
1.09A 2qhfA-2gmhA:
undetectable
2qhfA-2gmhA:
23.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VX9_A_RBFA1064_1
(DODECIN)
2gmh ELECTRON TRANSFER
FLAVOPROTEIN-UBIQUIN
ONE OXIDOREDUCTASE

(Sus
scrofa)
3 / 3 PHE A 198
VAL A  27
TRP A  24
None
0.83A 2vx9A-2gmhA:
undetectable
2vx9A-2gmhA:
6.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XN5_A_FUNA1356_2
(THYROXINE-BINDING
GLOBULIN)
2gmh ELECTRON TRANSFER
FLAVOPROTEIN-UBIQUIN
ONE OXIDOREDUCTASE

(Sus
scrofa)
3 / 3 LEU A 320
ARG A 325
ILE A 248
None
0.62A 2xn5B-2gmhA:
undetectable
2xn5B-2gmhA:
6.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y7W_B_SALB1300_1
(LYSR-TYPE REGULATORY
PROTEIN)
2gmh ELECTRON TRANSFER
FLAVOPROTEIN-UBIQUIN
ONE OXIDOREDUCTASE

(Sus
scrofa)
5 / 10 ILE A 123
GLY A 115
PHE A 114
GLY A 263
THR A 118
None
None
UQ5  A 612 (-4.1A)
None
None
1.18A 2y7wB-2gmhA:
0.9
2y7wB-2gmhA:
17.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YGN_A_PCFA1179_1
(WNT INHIBITORY
FACTOR 1)
2gmh ELECTRON TRANSFER
FLAVOPROTEIN-UBIQUIN
ONE OXIDOREDUCTASE

(Sus
scrofa)
4 / 5 ILE A 519
PHE A 535
PRO A 299
PHE A 527
None
1.29A 2ygnA-2gmhA:
undetectable
2ygnA-2gmhA:
12.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CYX_A_ROCA201_1
(HIV-1 PROTEASE)
2gmh ELECTRON TRANSFER
FLAVOPROTEIN-UBIQUIN
ONE OXIDOREDUCTASE

(Sus
scrofa)
5 / 12 LEU A 350
GLY A 374
ALA A  50
VAL A 208
ILE A 210
None
1.04A 3cyxA-2gmhA:
undetectable
3cyxA-2gmhA:
10.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DD1_A_CFFA903_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)
2gmh ELECTRON TRANSFER
FLAVOPROTEIN-UBIQUIN
ONE OXIDOREDUCTASE

(Sus
scrofa)
4 / 6 HIS A 216
ALA A 332
GLY A 239
TYR A 238
None
0.98A 3dd1A-2gmhA:
2.2
3dd1A-2gmhA:
21.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DD1_B_CFFB903_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)
2gmh ELECTRON TRANSFER
FLAVOPROTEIN-UBIQUIN
ONE OXIDOREDUCTASE

(Sus
scrofa)
4 / 6 HIS A 216
ALA A 332
GLY A 239
TYR A 238
None
0.98A 3dd1B-2gmhA:
undetectable
3dd1B-2gmhA:
21.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DDS_A_CFFA904_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)
2gmh ELECTRON TRANSFER
FLAVOPROTEIN-UBIQUIN
ONE OXIDOREDUCTASE

(Sus
scrofa)
4 / 6 HIS A 216
ALA A 332
GLY A 239
TYR A 238
None
1.01A 3ddsA-2gmhA:
3.0
3ddsA-2gmhA:
21.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DDS_B_CFFB903_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)
2gmh ELECTRON TRANSFER
FLAVOPROTEIN-UBIQUIN
ONE OXIDOREDUCTASE

(Sus
scrofa)
4 / 6 HIS A 216
ALA A 332
GLY A 239
TYR A 238
None
0.99A 3ddsB-2gmhA:
undetectable
3ddsB-2gmhA:
21.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DDW_A_CFFA903_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)
2gmh ELECTRON TRANSFER
FLAVOPROTEIN-UBIQUIN
ONE OXIDOREDUCTASE

(Sus
scrofa)
4 / 6 HIS A 216
ALA A 332
GLY A 239
TYR A 238
None
1.01A 3ddwA-2gmhA:
2.3
3ddwA-2gmhA:
21.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DDW_B_CFFB903_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)
2gmh ELECTRON TRANSFER
FLAVOPROTEIN-UBIQUIN
ONE OXIDOREDUCTASE

(Sus
scrofa)
4 / 6 HIS A 216
ALA A 332
GLY A 239
TYR A 238
None
1.01A 3ddwB-2gmhA:
undetectable
3ddwB-2gmhA:
21.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EEO_A_SAMA328_1
(MODIFICATION
METHYLASE HHAI)
2gmh ELECTRON TRANSFER
FLAVOPROTEIN-UBIQUIN
ONE OXIDOREDUCTASE

(Sus
scrofa)
3 / 3 GLU A 379
SER A 409
VAL A 411
None
0.75A 3eeoA-2gmhA:
2.9
3eeoA-2gmhA:
21.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FUU_A_ADNA0_1
(DIMETHYLADENOSINE
TRANSFERASE)
2gmh ELECTRON TRANSFER
FLAVOPROTEIN-UBIQUIN
ONE OXIDOREDUCTASE

(Sus
scrofa)
5 / 12 VAL A  41
GLY A  42
GLY A  44
GLU A  71
ALA A 167
FAD  A 611 (-4.9A)
FAD  A 611 (-3.3A)
FAD  A 611 (-3.7A)
FAD  A 611 (-2.9A)
FAD  A 611 (-3.3A)
0.80A 3fuuA-2gmhA:
3.6
3fuuA-2gmhA:
18.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IJX_B_HCZB800_1
(GLUTAMATE RECEPTOR 2)
2gmh ELECTRON TRANSFER
FLAVOPROTEIN-UBIQUIN
ONE OXIDOREDUCTASE

(Sus
scrofa)
5 / 10 LEU A 406
SER A 373
ILE A 341
PRO A 342
GLY A 357
None
1.39A 3ijxB-2gmhA:
undetectable
3ijxD-2gmhA:
undetectable
3ijxB-2gmhA:
19.31
3ijxD-2gmhA:
19.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OYA_A_RLTA398_1
(PFV INTEGRASE)
2gmh ELECTRON TRANSFER
FLAVOPROTEIN-UBIQUIN
ONE OXIDOREDUCTASE

(Sus
scrofa)
4 / 8 ASP A 295
GLN A 462
GLN A 236
GLU A 335
None
1.10A 3oyaA-2gmhA:
undetectable
3oyaA-2gmhA:
20.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TZF_B_08DB280_1
(7,8-DIHYDROPTEROATE
SYNTHASE)
2gmh ELECTRON TRANSFER
FLAVOPROTEIN-UBIQUIN
ONE OXIDOREDUCTASE

(Sus
scrofa)
4 / 8 THR A  80
ARG A 331
GLY A  83
LYS A 243
FAD  A 611 ( 4.7A)
FAD  A 611 (-4.1A)
FAD  A 611 (-3.9A)
None
1.08A 3tzfB-2gmhA:
undetectable
3tzfB-2gmhA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V4T_D_ACTD502_0
(UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE)
2gmh ELECTRON TRANSFER
FLAVOPROTEIN-UBIQUIN
ONE OXIDOREDUCTASE

(Sus
scrofa)
3 / 3 GLY A 366
THR A 369
ASN A 360
FAD  A 611 (-3.3A)
None
None
0.68A 3v4tD-2gmhA:
undetectable
3v4tD-2gmhA:
22.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V81_A_NVPA901_1
(HIV-1 REVERSE
TRANSCRIPTASE P66
SUBUNIT)
2gmh ELECTRON TRANSFER
FLAVOPROTEIN-UBIQUIN
ONE OXIDOREDUCTASE

(Sus
scrofa)
4 / 8 LEU A 204
VAL A  41
TYR A 165
LEU A 202
None
FAD  A 611 (-4.9A)
None
None
1.07A 3v81A-2gmhA:
2.0
3v81A-2gmhA:
22.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WSJ_A_MK1A201_2
(PROTEASE)
2gmh ELECTRON TRANSFER
FLAVOPROTEIN-UBIQUIN
ONE OXIDOREDUCTASE

(Sus
scrofa)
4 / 7 LEU A 350
ALA A  50
VAL A 159
ILE A 210
None
0.65A 3wsjB-2gmhA:
undetectable
3wsjB-2gmhA:
11.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DXU_A_ACAA711_1
(LACTOTRANSFERRIN)
2gmh ELECTRON TRANSFER
FLAVOPROTEIN-UBIQUIN
ONE OXIDOREDUCTASE

(Sus
scrofa)
4 / 6 GLY A 531
PRO A 529
GLY A 329
GLU A 244
None
SF4  A 610 ( 4.3A)
None
None
0.88A 4dxuA-2gmhA:
undetectable
4dxuA-2gmhA:
21.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E1V_A_URFA1301_1
(URIDINE
PHOSPHORYLASE)
2gmh ELECTRON TRANSFER
FLAVOPROTEIN-UBIQUIN
ONE OXIDOREDUCTASE

(Sus
scrofa)
4 / 8 GLY A 293
ILE A 240
VAL A 292
PRO A 303
None
0.96A 4e1vA-2gmhA:
undetectable
4e1vA-2gmhA:
17.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E1V_B_URFB1301_1
(URIDINE
PHOSPHORYLASE)
2gmh ELECTRON TRANSFER
FLAVOPROTEIN-UBIQUIN
ONE OXIDOREDUCTASE

(Sus
scrofa)
4 / 7 GLY A 293
ILE A 240
VAL A 292
PRO A 303
None
0.91A 4e1vB-2gmhA:
undetectable
4e1vB-2gmhA:
17.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E1V_C_URFC1301_1
(URIDINE
PHOSPHORYLASE)
2gmh ELECTRON TRANSFER
FLAVOPROTEIN-UBIQUIN
ONE OXIDOREDUCTASE

(Sus
scrofa)
4 / 8 GLY A 293
ILE A 240
VAL A 292
PRO A 303
None
0.98A 4e1vC-2gmhA:
undetectable
4e1vC-2gmhA:
17.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E1V_D_URFD1301_1
(URIDINE
PHOSPHORYLASE)
2gmh ELECTRON TRANSFER
FLAVOPROTEIN-UBIQUIN
ONE OXIDOREDUCTASE

(Sus
scrofa)
4 / 8 GLY A 293
ILE A 240
VAL A 292
PRO A 303
None
0.96A 4e1vD-2gmhA:
undetectable
4e1vD-2gmhA:
17.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E1V_E_URFE1301_1
(URIDINE
PHOSPHORYLASE)
2gmh ELECTRON TRANSFER
FLAVOPROTEIN-UBIQUIN
ONE OXIDOREDUCTASE

(Sus
scrofa)
4 / 8 GLY A 293
ILE A 240
VAL A 292
PRO A 303
None
0.94A 4e1vE-2gmhA:
undetectable
4e1vE-2gmhA:
17.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E1V_E_URFE1301_1
(URIDINE
PHOSPHORYLASE)
2gmh ELECTRON TRANSFER
FLAVOPROTEIN-UBIQUIN
ONE OXIDOREDUCTASE

(Sus
scrofa)
4 / 8 THR A 438
ILE A 421
VAL A 418
PRO A 362
UQ5  A 612 (-3.0A)
None
None
None
0.95A 4e1vE-2gmhA:
undetectable
4e1vE-2gmhA:
17.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E1V_G_URFG1301_1
(URIDINE
PHOSPHORYLASE)
2gmh ELECTRON TRANSFER
FLAVOPROTEIN-UBIQUIN
ONE OXIDOREDUCTASE

(Sus
scrofa)
4 / 8 GLY A 293
ILE A 240
VAL A 292
PRO A 303
None
0.99A 4e1vG-2gmhA:
undetectable
4e1vG-2gmhA:
17.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E1V_H_URFH1301_1
(URIDINE
PHOSPHORYLASE)
2gmh ELECTRON TRANSFER
FLAVOPROTEIN-UBIQUIN
ONE OXIDOREDUCTASE

(Sus
scrofa)
4 / 8 GLY A 293
ILE A 240
VAL A 292
PRO A 303
None
0.95A 4e1vH-2gmhA:
undetectable
4e1vH-2gmhA:
17.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E1V_H_URFH1301_1
(URIDINE
PHOSPHORYLASE)
2gmh ELECTRON TRANSFER
FLAVOPROTEIN-UBIQUIN
ONE OXIDOREDUCTASE

(Sus
scrofa)
4 / 8 THR A 438
ILE A 421
VAL A 418
PRO A 362
UQ5  A 612 (-3.0A)
None
None
None
1.01A 4e1vH-2gmhA:
undetectable
4e1vH-2gmhA:
17.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FU8_A_ACTA302_0
(UROKINASE-TYPE
PLASMINOGEN
ACTIVATOR)
2gmh ELECTRON TRANSFER
FLAVOPROTEIN-UBIQUIN
ONE OXIDOREDUCTASE

(Sus
scrofa)
4 / 5 HIS A 312
GLN A 480
GLY A 479
SER A 482
None
1.00A 4fu8A-2gmhA:
undetectable
4fu8A-2gmhA:
17.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HLA_A_017A200_1
(PROTEASE)
2gmh ELECTRON TRANSFER
FLAVOPROTEIN-UBIQUIN
ONE OXIDOREDUCTASE

(Sus
scrofa)
5 / 12 LEU A 350
GLY A 374
ALA A  50
VAL A 208
ILE A 210
None
1.00A 4hlaA-2gmhA:
undetectable
4hlaA-2gmhA:
11.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HLA_A_017A200_2
(PROTEASE)
2gmh ELECTRON TRANSFER
FLAVOPROTEIN-UBIQUIN
ONE OXIDOREDUCTASE

(Sus
scrofa)
5 / 11 LEU A 350
GLY A 374
ALA A  50
VAL A 208
ILE A 210
None
1.01A 4hlaB-2gmhA:
undetectable
4hlaB-2gmhA:
11.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KR4_C_AICC401_1
(OUTER MEMBRANE
PROTEIN F)
2gmh ELECTRON TRANSFER
FLAVOPROTEIN-UBIQUIN
ONE OXIDOREDUCTASE

(Sus
scrofa)
4 / 8 LYS A 456
ARG A 422
ASP A 267
GLU A 306
None
1.38A 4kr4C-2gmhA:
undetectable
4kr4C-2gmhA:
19.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LL3_A_017A201_1
(PROTEASE)
2gmh ELECTRON TRANSFER
FLAVOPROTEIN-UBIQUIN
ONE OXIDOREDUCTASE

(Sus
scrofa)
5 / 8 ALA A  51
VAL A  38
GLY A 374
VAL A  41
ILE A  40
None
None
None
FAD  A 611 (-4.9A)
None
1.35A 4ll3A-2gmhA:
undetectable
4ll3A-2gmhA:
11.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LNX_A_T44A501_1
(THYROID HORMONE
RECEPTOR ALPHA)
2gmh ELECTRON TRANSFER
FLAVOPROTEIN-UBIQUIN
ONE OXIDOREDUCTASE

(Sus
scrofa)
4 / 6 SER A 340
GLU A 234
GLN A 339
VAL A 361
None
1.24A 4lnxA-2gmhA:
undetectable
4lnxA-2gmhA:
18.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OK1_A_198A1001_1
(ANDROGEN RECEPTOR)
2gmh ELECTRON TRANSFER
FLAVOPROTEIN-UBIQUIN
ONE OXIDOREDUCTASE

(Sus
scrofa)
5 / 12 LEU A  48
GLY A  47
VAL A  70
ILE A 381
VAL A 208
None
1.11A 4ok1A-2gmhA:
undetectable
4ok1A-2gmhA:
16.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OKW_A_198A1001_1
(ANDROGEN RECEPTOR)
2gmh ELECTRON TRANSFER
FLAVOPROTEIN-UBIQUIN
ONE OXIDOREDUCTASE

(Sus
scrofa)
5 / 12 LEU A  48
GLY A  47
VAL A  70
ILE A 381
VAL A 208
None
1.17A 4okwA-2gmhA:
undetectable
4okwA-2gmhA:
16.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OT2_A_NPSA602_1
(SERUM ALBUMIN)
2gmh ELECTRON TRANSFER
FLAVOPROTEIN-UBIQUIN
ONE OXIDOREDUCTASE

(Sus
scrofa)
4 / 6 ARG A 200
ALA A 182
ASP A 185
LEU A 171
None
0.95A 4ot2A-2gmhA:
2.8
4ot2A-2gmhA:
21.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PWD_A_NVPA901_1
(HIV-1 REVERSE
TRANSCRIPTASE, P66
SUBUNIT)
2gmh ELECTRON TRANSFER
FLAVOPROTEIN-UBIQUIN
ONE OXIDOREDUCTASE

(Sus
scrofa)
4 / 8 LEU A 204
VAL A  41
TYR A 165
LEU A 202
None
FAD  A 611 (-4.9A)
None
None
1.03A 4pwdA-2gmhA:
undetectable
4pwdA-2gmhA:
22.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4S0V_A_SUVA2001_2
(HUMAN OREXIN
RECEPTOR TYPE 2
FUSION PROTEIN TO P.
ABYSII GLYCOGEN
SYNTHASE)
2gmh ELECTRON TRANSFER
FLAVOPROTEIN-UBIQUIN
ONE OXIDOREDUCTASE

(Sus
scrofa)
4 / 5 PRO A 132
HIS A 368
TYR A 277
VAL A 258
None
1.34A 4s0vA-2gmhA:
4.4
4s0vA-2gmhA:
21.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4S0V_A_SUVA2001_2
(HUMAN OREXIN
RECEPTOR TYPE 2
FUSION PROTEIN TO P.
ABYSII GLYCOGEN
SYNTHASE)
2gmh ELECTRON TRANSFER
FLAVOPROTEIN-UBIQUIN
ONE OXIDOREDUCTASE

(Sus
scrofa)
4 / 5 PRO A 362
HIS A 368
TYR A 277
VAL A 258
None
1.14A 4s0vA-2gmhA:
4.4
4s0vA-2gmhA:
21.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XDR_A_ADNA402_1
(FAD:PROTEIN FMN
TRANSFERASE)
2gmh ELECTRON TRANSFER
FLAVOPROTEIN-UBIQUIN
ONE OXIDOREDUCTASE

(Sus
scrofa)
5 / 12 GLY A 217
ALA A 220
ILE A 170
ILE A 181
VAL A 178
None
0.98A 4xdrA-2gmhA:
undetectable
4xdrA-2gmhA:
21.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XE5_A_OBNA1104_2
(SODIUM/POTASSIUM-TRA
NSPORTING ATPASE
SUBUNIT ALPHA-1)
2gmh ELECTRON TRANSFER
FLAVOPROTEIN-UBIQUIN
ONE OXIDOREDUCTASE

(Sus
scrofa)
4 / 6 PRO A 512
ILE A 568
VAL A 532
PHE A 527
None
None
SF4  A 610 ( 4.3A)
None
1.19A 4xe5A-2gmhA:
2.9
4xe5A-2gmhA:
19.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XUM_A_IMNA502_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)
2gmh ELECTRON TRANSFER
FLAVOPROTEIN-UBIQUIN
ONE OXIDOREDUCTASE

(Sus
scrofa)
4 / 7 GLU A 335
ILE A 240
CYH A 556
ILE A 561
None
None
SF4  A 610 (-2.2A)
None
0.97A 4xumA-2gmhA:
undetectable
4xumA-2gmhA:
19.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XV2_A_P06A801_2
(SERINE/THREONINE-PRO
TEIN KINASE B-RAF)
2gmh ELECTRON TRANSFER
FLAVOPROTEIN-UBIQUIN
ONE OXIDOREDUCTASE

(Sus
scrofa)
4 / 4 GLY A 214
LEU A 415
PHE A 338
ILE A 341
FAD  A 611 (-3.4A)
None
None
None
0.89A 4xv2A-2gmhA:
undetectable
4xv2A-2gmhA:
20.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z7F_C_FOLC201_0
(FOLATE ECF
TRANSPORTER)
2gmh ELECTRON TRANSFER
FLAVOPROTEIN-UBIQUIN
ONE OXIDOREDUCTASE

(Sus
scrofa)
5 / 12 SER A 487
ALA A 330
PHE A 290
PHE A 307
LEU A 288
None
1.33A 4z7fC-2gmhA:
undetectable
4z7fC-2gmhA:
19.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_L_TRPL101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
2gmh ELECTRON TRANSFER
FLAVOPROTEIN-UBIQUIN
ONE OXIDOREDUCTASE

(Sus
scrofa)
4 / 8 SER A 492
GLY A 577
HIS A 496
ALA A 580
EDO  A 621 ( 4.6A)
EDO  A 619 (-3.2A)
None
EDO  A 624 (-3.5A)
0.85A 5eezL-2gmhA:
undetectable
5eezV-2gmhA:
undetectable
5eezL-2gmhA:
8.82
5eezV-2gmhA:
8.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_L_TRPL101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
2gmh ELECTRON TRANSFER
FLAVOPROTEIN-UBIQUIN
ONE OXIDOREDUCTASE

(Sus
scrofa)
4 / 8 SER A 492
GLY A 577
HIS A 496
ALA A 580
EDO  A 621 ( 4.6A)
EDO  A 619 (-3.2A)
None
EDO  A 624 (-3.5A)
0.85A 5ef1L-2gmhA:
undetectable
5ef1V-2gmhA:
undetectable
5ef1L-2gmhA:
8.82
5ef1V-2gmhA:
8.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_L_TRPL101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
2gmh ELECTRON TRANSFER
FLAVOPROTEIN-UBIQUIN
ONE OXIDOREDUCTASE

(Sus
scrofa)
4 / 8 SER A 492
GLY A 577
HIS A 496
ALA A 580
EDO  A 621 ( 4.6A)
EDO  A 619 (-3.2A)
None
EDO  A 624 (-3.5A)
0.85A 5ef2L-2gmhA:
undetectable
5ef2V-2gmhA:
undetectable
5ef2L-2gmhA:
8.82
5ef2V-2gmhA:
8.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EVY_X_SALX502_1
(SALICYLATE
HYDROXYLASE)
2gmh ELECTRON TRANSFER
FLAVOPROTEIN-UBIQUIN
ONE OXIDOREDUCTASE

(Sus
scrofa)
4 / 5 SER A 488
GLN A 308
LEU A 242
PHE A 304
None
1.41A 5evyX-2gmhA:
18.2
5evyX-2gmhA:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IK1_A_CAMA503_0
(CAMPHOR
5-MONOOXYGENASE)
2gmh ELECTRON TRANSFER
FLAVOPROTEIN-UBIQUIN
ONE OXIDOREDUCTASE

(Sus
scrofa)
4 / 7 GLY A 180
VAL A  70
ILE A  40
VAL A  41
None
None
None
FAD  A 611 (-4.9A)
0.65A 5ik1A-2gmhA:
undetectable
5ik1A-2gmhA:
20.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JH7_B_6K9B503_1
(TUBULIN ALPHA-1B
CHAIN
TUBULIN BETA-2B
CHAIN)
2gmh ELECTRON TRANSFER
FLAVOPROTEIN-UBIQUIN
ONE OXIDOREDUCTASE

(Sus
scrofa)
4 / 7 LEU A 294
GLU A 306
ILE A 364
VAL A 291
None
None
UQ5  A 612 ( 4.8A)
UQ5  A 612 ( 4.9A)
1.21A 5jh7C-2gmhA:
undetectable
5jh7C-2gmhA:
20.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NY7_A_NCAA303_0
(AMIDASE)
2gmh ELECTRON TRANSFER
FLAVOPROTEIN-UBIQUIN
ONE OXIDOREDUCTASE

(Sus
scrofa)
4 / 6 ARG A 257
GLY A 256
THR A 110
GLU A 111
None
0.91A 5ny7A-2gmhA:
undetectable
5ny7A-2gmhA:
21.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5O96_C_SAMC501_0
(RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE E)
2gmh ELECTRON TRANSFER
FLAVOPROTEIN-UBIQUIN
ONE OXIDOREDUCTASE

(Sus
scrofa)
4 / 7 GLY A  47
GLY A  42
SER A 148
ALA A 154
None
FAD  A 611 (-3.3A)
None
None
0.77A 5o96C-2gmhA:
2.0
5o96C-2gmhA:
17.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X6Y_A_SAMA901_0
(MRNA CAPPING ENZYME
P5)
2gmh ELECTRON TRANSFER
FLAVOPROTEIN-UBIQUIN
ONE OXIDOREDUCTASE

(Sus
scrofa)
5 / 11 VAL A  41
GLY A  42
GLU A  71
ALA A 167
LEU A 219
FAD  A 611 (-4.9A)
FAD  A 611 (-3.3A)
FAD  A 611 (-2.9A)
FAD  A 611 (-3.3A)
FAD  A 611 (-4.4A)
0.73A 5x6yA-2gmhA:
undetectable
5x6yA-2gmhA:
21.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X6Y_B_SAMB901_0
(MRNA CAPPING ENZYME
P5)
2gmh ELECTRON TRANSFER
FLAVOPROTEIN-UBIQUIN
ONE OXIDOREDUCTASE

(Sus
scrofa)
5 / 10 VAL A  41
GLY A  42
GLU A  71
ALA A 167
LEU A 219
FAD  A 611 (-4.9A)
FAD  A 611 (-3.3A)
FAD  A 611 (-2.9A)
FAD  A 611 (-3.3A)
FAD  A 611 (-4.4A)
0.74A 5x6yB-2gmhA:
undetectable
5x6yB-2gmhA:
21.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X6Y_C_SAMC901_0
(MRNA CAPPING ENZYME
P5)
2gmh ELECTRON TRANSFER
FLAVOPROTEIN-UBIQUIN
ONE OXIDOREDUCTASE

(Sus
scrofa)
5 / 11 VAL A  41
GLY A  42
GLU A  71
ALA A 167
LEU A 219
FAD  A 611 (-4.9A)
FAD  A 611 (-3.3A)
FAD  A 611 (-2.9A)
FAD  A 611 (-3.3A)
FAD  A 611 (-4.4A)
0.65A 5x6yC-2gmhA:
undetectable
5x6yC-2gmhA:
21.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Y2T_B_8LXB501_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)
2gmh ELECTRON TRANSFER
FLAVOPROTEIN-UBIQUIN
ONE OXIDOREDUCTASE

(Sus
scrofa)
4 / 8 HIS A 368
PHE A 358
SER A 409
LEU A 344
None
1.10A 5y2tB-2gmhA:
undetectable
5y2tB-2gmhA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZRD_A_CUA606_0
(TYROSINASE)
2gmh ELECTRON TRANSFER
FLAVOPROTEIN-UBIQUIN
ONE OXIDOREDUCTASE

(Sus
scrofa)
4 / 4 HIS A 555
CYH A 553
HIS A 503
HIS A 496
None
SF4  A 610 (-2.3A)
None
None
1.01A 5zrdA-2gmhA:
undetectable
5zrdA-2gmhA:
22.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZRD_B_CUB607_0
(TYROSINASE)
2gmh ELECTRON TRANSFER
FLAVOPROTEIN-UBIQUIN
ONE OXIDOREDUCTASE

(Sus
scrofa)
4 / 5 HIS A 555
CYH A 553
HIS A 503
HIS A 496
None
SF4  A 610 (-2.3A)
None
None
0.97A 5zrdB-2gmhA:
undetectable
5zrdB-2gmhA:
22.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZRD_C_CUC605_0
(TYROSINASE)
2gmh ELECTRON TRANSFER
FLAVOPROTEIN-UBIQUIN
ONE OXIDOREDUCTASE

(Sus
scrofa)
4 / 5 HIS A 555
CYH A 553
HIS A 503
HIS A 496
None
SF4  A 610 (-2.3A)
None
None
1.01A 5zrdC-2gmhA:
undetectable
5zrdC-2gmhA:
22.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZRD_D_CUD606_0
(TYROSINASE)
2gmh ELECTRON TRANSFER
FLAVOPROTEIN-UBIQUIN
ONE OXIDOREDUCTASE

(Sus
scrofa)
4 / 5 HIS A 555
CYH A 553
HIS A 503
HIS A 496
None
SF4  A 610 (-2.3A)
None
None
1.07A 5zrdD-2gmhA:
undetectable
5zrdD-2gmhA:
22.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BAA_E_GBME2001_2
(ATP-BINDING CASSETTE
SUB-FAMILY C MEMBER
8)
2gmh ELECTRON TRANSFER
FLAVOPROTEIN-UBIQUIN
ONE OXIDOREDUCTASE

(Sus
scrofa)
3 / 3 LEU A 245
THR A 107
ASN A 106
None
0.72A 6baaE-2gmhA:
undetectable
6baaE-2gmhA:
16.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BAA_F_GBMF2001_2
(ATP-BINDING CASSETTE
SUB-FAMILY C MEMBER
8)
2gmh ELECTRON TRANSFER
FLAVOPROTEIN-UBIQUIN
ONE OXIDOREDUCTASE

(Sus
scrofa)
3 / 3 LEU A 245
THR A 107
ASN A 106
None
0.72A 6baaF-2gmhA:
undetectable
6baaF-2gmhA:
16.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BAA_G_GBMG2001_2
(ATP-BINDING CASSETTE
SUB-FAMILY C MEMBER
8)
2gmh ELECTRON TRANSFER
FLAVOPROTEIN-UBIQUIN
ONE OXIDOREDUCTASE

(Sus
scrofa)
3 / 3 LEU A 245
THR A 107
ASN A 106
None
0.73A 6baaG-2gmhA:
undetectable
6baaG-2gmhA:
16.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BAA_H_GBMH2001_2
(ATP-BINDING CASSETTE
SUB-FAMILY C MEMBER
8)
2gmh ELECTRON TRANSFER
FLAVOPROTEIN-UBIQUIN
ONE OXIDOREDUCTASE

(Sus
scrofa)
3 / 3 LEU A 245
THR A 107
ASN A 106
None
0.73A 6baaH-2gmhA:
undetectable
6baaH-2gmhA:
16.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6D8P_B_ACTB804_0
(UNCHARACTERIZED
PROTEIN)
2gmh ELECTRON TRANSFER
FLAVOPROTEIN-UBIQUIN
ONE OXIDOREDUCTASE

(Sus
scrofa)
4 / 4 HIS A 218
VAL A  41
LEU A 219
ALA A 168
EDO  A 622 ( 3.6A)
FAD  A 611 (-4.9A)
FAD  A 611 (-4.4A)
EDO  A 622 (-3.4A)
1.28A 6d8pB-2gmhA:
undetectable
6d8pB-2gmhA:
20.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EKZ_A_SNPA413_0
(AROMATIC
PEROXYGENASE)
2gmh ELECTRON TRANSFER
FLAVOPROTEIN-UBIQUIN
ONE OXIDOREDUCTASE

(Sus
scrofa)
4 / 7 ASP A 459
GLY A 272
GLY A 293
VAL A 291
None
UQ5  A 612 (-3.3A)
None
UQ5  A 612 ( 4.9A)
0.98A 6ekzA-2gmhA:
undetectable
6ekzA-2gmhA:
9.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GNE_A_ACRA602_1
(-)
2gmh ELECTRON TRANSFER
FLAVOPROTEIN-UBIQUIN
ONE OXIDOREDUCTASE

(Sus
scrofa)
5 / 12 GLY A 577
GLY A 578
VAL A 554
VAL A 489
GLY A 493
EDO  A 619 (-3.2A)
None
SF4  A 610 (-4.1A)
EDO  A 621 (-4.5A)
EDO  A 624 (-3.7A)
1.02A 6gneA-2gmhA:
4.0
6gneA-2gmhA:
21.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GNE_B_ACRB602_1
(-)
2gmh ELECTRON TRANSFER
FLAVOPROTEIN-UBIQUIN
ONE OXIDOREDUCTASE

(Sus
scrofa)
5 / 12 GLY A 577
GLY A 578
VAL A 554
VAL A 489
GLY A 493
EDO  A 619 (-3.2A)
None
SF4  A 610 (-4.1A)
EDO  A 621 (-4.5A)
EDO  A 624 (-3.7A)
1.02A 6gneB-2gmhA:
2.0
6gneB-2gmhA:
21.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GQI_A_ACTA604_0
(CYCLOHEXANONE
MONOOXYGENASE FROM
THERMOCRISPUM
MUNICIPALE)
2gmh ELECTRON TRANSFER
FLAVOPROTEIN-UBIQUIN
ONE OXIDOREDUCTASE

(Sus
scrofa)
4 / 6 TRP A 246
ILE A 481
GLY A 322
GLU A 321
None
1.04A 6gqiA-2gmhA:
7.4
6gqiA-2gmhA:
20.90