SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2gmq'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3TBG_D_RTZD2_1 (CYTOCHROME P450 2D6)	2gmq	HYPOTHETICAL PROTEIN EF0006 (Enterococcus faecalis)	5 / 9	LEU A 64 THR A 63 LEU A 34 ILE A 99 PHE A 108	None	1.01A	3tbgD-2gmqA: undetectable	3tbgD-2gmqA: 13.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3TBG_D_RTZD2_1 (CYTOCHROME P450 2D6)	2gmq	HYPOTHETICAL PROTEIN EF0006 (Enterococcus faecalis)	5 / 9	LEU A 64 THR A 63 VAL A 77 LEU A 34 ILE A 99	None	1.04A	3tbgD-2gmqA: undetectable	3tbgD-2gmqA: 13.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5WP1_A_BEZA403_0 (MITOGEN-ACTIVATED PROTEIN KINASE 1)	2gmq	HYPOTHETICAL PROTEIN EF0006 (Enterococcus faecalis)	4 / 4	GLY A 113 PHE A 112 ASN A 69 LYS A 71	None	1.08A	5wp1A-2gmqA: 0.1	5wp1A-2gmqA: 17.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6NMP_C_CHDC307_0 (CYTOCHROME C OXIDASE SUBUNIT 3 CYTOCHROME C OXIDASE SUBUNIT 7A1, MITOCHONDRIAL)	2gmq	HYPOTHETICAL PROTEIN EF0006 (Enterococcus faecalis)	4 / 6	LYS A 100 PHE A 97 LEU A 34 PHE A 108	None	1.29A	6nmpC-2gmqA: undetectable 6nmpJ-2gmqA: undetectable	6nmpC-2gmqA: 18.57 6nmpJ-2gmqA: 21.19

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["3TBG_D_RTZD2_1","CYTOCHROME P450 2D6","2gmq","HYPOTHETICAL PROTEIN EF0006","Enterococcus faecalis",5,"LEU A  64;THR A  63;LEU A  34;ILE A  99;PHE A 108","None","1.01A","3tbgD-2gmqA:undetectable","3tbgD-2gmqA:13.14"],["3TBG_D_RTZD2_1","CYTOCHROME P450 2D6","2gmq","HYPOTHETICAL PROTEIN EF0006","Enterococcus faecalis",5,"LEU A  64;THR A  63;VAL A  77;LEU A  34;ILE A  99","None","1.04A","3tbgD-2gmqA:undetectable","3tbgD-2gmqA:13.14"],["5WP1_A_BEZA403_0","MITOGEN-ACTIVATED PROTEIN KINASE 1","2gmq","HYPOTHETICAL PROTEIN EF0006","Enterococcus faecalis",4,"GLY A 113;PHE A 112;ASN A  69;LYS A  71","None","1.08A","5wp1A-2gmqA:0.1","5wp1A-2gmqA:17.23"],["6NMP_C_CHDC307_0","CYTOCHROME C OXIDASE SUBUNIT 3;CYTOCHROME C OXIDASE SUBUNIT 7A1, MITOCHONDRIAL","2gmq","HYPOTHETICAL PROTEIN EF0006","Enterococcus faecalis",4,"LYS A 100;PHE A  97;LEU A  34;PHE A 108","None","1.29A","6nmpC-2gmqA:undetectable;6nmpJ-2gmqA:undetectable","6nmpC-2gmqA:18.57;6nmpJ-2gmqA:21.19"]]