SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2gmy'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1N5X_A_TEIA3006_1
(XANTHINE
DEHYDROGENASE)		 2gmy HYPOTHETICAL PROTEIN
ATU0492
(Agrobacterium
fabrum) 		5 / 12 LEU A 111
LEU A  88
THR A  96
VAL A  95
ALA A 126
 None
 1.17A 1n5xA-2gmyA:
undetectable		 1n5xA-2gmyA:
8.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1N5X_B_TEIB4006_1
(XANTHINE
DEHYDROGENASE)		 2gmy HYPOTHETICAL PROTEIN
ATU0492
(Agrobacterium
fabrum) 		5 / 12 LEU A 111
LEU A  88
THR A  96
VAL A  95
ALA A 126
 None
 1.17A 1n5xB-2gmyA:
undetectable		 1n5xB-2gmyA:
8.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZM7_A_ACAA501_1
(6-AMINOHEXANOATE-DIM
ER HYDROLASE)		 2gmy HYPOTHETICAL PROTEIN
ATU0492
(Agrobacterium
fabrum) 		4 / 7 ALA A 126
ILE A 130
ILE A  35
HIS A  55
 None
 0.95A 2zm7A-2gmyA:
undetectable		 2zm7A-2gmyA:
16.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ADS_A_IMNA2_2
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 2gmy HYPOTHETICAL PROTEIN
ATU0492
(Agrobacterium
fabrum) 		4 / 6 ILE A 123
ILE A  45
LEU A  30
PHE A  34
 None
 0.90A 3adsA-2gmyA:
undetectable		 3adsA-2gmyA:
19.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ADX_A_IMNA2_2
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 2gmy HYPOTHETICAL PROTEIN
ATU0492
(Agrobacterium
fabrum) 		4 / 7 ILE A 123
ILE A  45
LEU A  30
PHE A  34
 None
 0.90A 3adxA-2gmyA:
undetectable		 3adxA-2gmyA:
19.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DDY_A_RBFA187_1
(LUMAZINE PROTEIN)		 2gmy HYPOTHETICAL PROTEIN
ATU0492
(Agrobacterium
fabrum) 		5 / 12 VAL A 138
ASN A 134
ILE A 130
ALA A  42
ILE A  44
 None
 1.19A 3ddyA-2gmyA:
undetectable		 3ddyA-2gmyA:
22.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KIR_A_RCXA601_2
(PROSTAGLANDIN G/H
SYNTHASE 2)		 2gmy HYPOTHETICAL PROTEIN
ATU0492
(Agrobacterium
fabrum) 		3 / 3 ARG A 141
ILE A   5
PHE A 140
 None
 0.54A 5kirA-2gmyA:
undetectable		 5kirA-2gmyA:
13.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N5D_A_SAMA306_1
(METHYLTRANSFERASE)		 2gmy HYPOTHETICAL PROTEIN
ATU0492
(Agrobacterium
fabrum) 		4 / 7 ILE A  98
GLU A 100
ASP A  93
ASN A  46
 None
 0.92A 5n5dA-2gmyA:
undetectable		 5n5dA-2gmyA:
21.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X66_F_MTXF402_1
(THYMIDYLATE SYNTHASE)		 2gmy HYPOTHETICAL PROTEIN
ATU0492
(Agrobacterium
fabrum) 		5 / 12 ILE A 123
ASP A  93
LEU A  89
GLY A  90
THR A  82
 None
 0.94A 5x66F-2gmyA:
undetectable		 5x66F-2gmyA:
17.93