SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2gn1'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_C_TRPC81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 2gn1 THREONINE
DEHYDRATASE
CATABOLIC
(Salmonella
enterica) 		5 / 10 SER A 219
ALA A 218
GLY A 184
ALA A 217
ILE A 183
 None
None
LLP  A  58 ( 3.5A)
None
None
 1.10A 1gtnB-2gn1A:
undetectable
1gtnC-2gn1A:
undetectable		 1gtnB-2gn1A:
11.99
1gtnC-2gn1A:
11.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_C_TRPC81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 2gn1 THREONINE
DEHYDRATASE
CATABOLIC
(Salmonella
enterica) 		5 / 10 SER A 219
ALA A 218
GLY A 185
ALA A 217
ILE A 183
 None
None
LLP  A  58 ( 3.8A)
None
None
 1.13A 1gtnB-2gn1A:
undetectable
1gtnC-2gn1A:
undetectable		 1gtnB-2gn1A:
11.99
1gtnC-2gn1A:
11.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_M_TRPM81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 2gn1 THREONINE
DEHYDRATASE
CATABOLIC
(Salmonella
enterica) 		5 / 11 GLY A 184
ALA A 217
ILE A 183
SER A 219
ALA A 218
 LLP  A  58 ( 3.5A)
None
None
None
None
 1.10A 1gtnM-2gn1A:
undetectable
1gtnN-2gn1A:
undetectable		 1gtnM-2gn1A:
11.99
1gtnN-2gn1A:
11.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_M_TRPM81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 2gn1 THREONINE
DEHYDRATASE
CATABOLIC
(Salmonella
enterica) 		5 / 11 GLY A 185
ALA A 217
ILE A 183
SER A 219
ALA A 218
 LLP  A  58 ( 3.8A)
None
None
None
None
 1.10A 1gtnM-2gn1A:
undetectable
1gtnN-2gn1A:
undetectable		 1gtnM-2gn1A:
11.99
1gtnN-2gn1A:
11.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_U_TRPU81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 2gn1 THREONINE
DEHYDRATASE
CATABOLIC
(Salmonella
enterica) 		5 / 10 GLY A 184
ALA A 217
ILE A 183
SER A 219
ALA A 218
 LLP  A  58 ( 3.5A)
None
None
None
None
 1.12A 1gtnU-2gn1A:
undetectable
1gtnV-2gn1A:
undetectable		 1gtnU-2gn1A:
11.99
1gtnV-2gn1A:
11.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_U_TRPU81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 2gn1 THREONINE
DEHYDRATASE
CATABOLIC
(Salmonella
enterica) 		5 / 10 GLY A 185
ALA A 217
ILE A 183
SER A 219
ALA A 218
 LLP  A  58 ( 3.8A)
None
None
None
None
 1.14A 1gtnU-2gn1A:
undetectable
1gtnV-2gn1A:
undetectable		 1gtnU-2gn1A:
11.99
1gtnV-2gn1A:
11.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HXW_B_RITB301_2
(HIV-1 PROTEASE)		 2gn1 THREONINE
DEHYDRATASE
CATABOLIC
(Salmonella
enterica) 		6 / 11 GLY A 285
ALA A 284
ASP A 236
GLY A 184
ILE A 183
VAL A 261
 LLP  A  58 ( 4.8A)
LLP  A  58 ( 3.4A)
None
LLP  A  58 ( 3.5A)
None
None
 1.47A 1hxwB-2gn1A:
undetectable		 1hxwB-2gn1A:
15.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MCN_P_DHIP1_0
(IMMUNOGLOBULIN
LAMBDA DIMER MCG
(LIGHT CHAIN)
PEPTIDE
N-ACETYL-D-HIS-L-PRO
-NH2)		 2gn1 THREONINE
DEHYDRATASE
CATABOLIC
(Salmonella
enterica) 		3 / 3 PHE A 149
TYR A 153
PRO A 151
 None
LLP  A  58 ( 4.8A)
None
 0.91A 1mcnA-2gn1A:
undetectable
1mcnB-2gn1A:
undetectable
1mcnP-2gn1A:
undetectable		 1mcnA-2gn1A:
20.81
1mcnB-2gn1A:
20.81
1mcnP-2gn1A:
9.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OG5_A_SWFA502_1
(CYTOCHROME P450 2C9)		 2gn1 THREONINE
DEHYDRATASE
CATABOLIC
(Salmonella
enterica) 		5 / 12 LEU A  46
LEU A 273
LEU A 287
PRO A 182
LEU A 188
 None
None
None
LLP  A  58 ( 4.6A)
LLP  A  58 ( 4.5A)
 1.23A 1og5A-2gn1A:
undetectable		 1og5A-2gn1A:
21.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OG5_B_SWFB502_1
(CYTOCHROME P450 2C9)		 2gn1 THREONINE
DEHYDRATASE
CATABOLIC
(Salmonella
enterica) 		5 / 12 ILE A 180
LEU A  46
LEU A 287
PRO A 182
LEU A 188
 None
None
None
LLP  A  58 ( 4.6A)
LLP  A  58 ( 4.5A)
 1.23A 1og5B-2gn1A:
undetectable		 1og5B-2gn1A:
21.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QZZ_A_ACTA421_0
(ACLACINOMYCIN-10-HYD
ROXYLASE)		 2gn1 THREONINE
DEHYDRATASE
CATABOLIC
(Salmonella
enterica) 		4 / 8 GLY A 191
GLY A 187
GLY A 186
LEU A 188
 None
LLP  A  58 ( 3.2A)
LLP  A  58 ( 3.4A)
LLP  A  58 ( 4.5A)
 0.65A 1qzzA-2gn1A:
2.5		 1qzzA-2gn1A:
23.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SG9_A_SAMA301_0
(HEMK PROTEIN)		 2gn1 THREONINE
DEHYDRATASE
CATABOLIC
(Salmonella
enterica) 		5 / 12 PHE A  57
GLY A  61
ILE A 159
VAL A  90
PHE A 149
 LLP  A  58 ( 3.8A)
LLP  A  58 ( 4.2A)
None
None
None
 1.24A 1sg9A-2gn1A:
3.4		 1sg9A-2gn1A:
22.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_T_TRPT81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2gn1 THREONINE
DEHYDRATASE
CATABOLIC
(Salmonella
enterica) 		5 / 10 GLY A 184
ALA A 217
ILE A 183
SER A 219
ALA A 218
 LLP  A  58 ( 3.5A)
None
None
None
None
 1.12A 1utdT-2gn1A:
undetectable
1utdU-2gn1A:
undetectable		 1utdT-2gn1A:
11.99
1utdU-2gn1A:
11.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_T_TRPT81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2gn1 THREONINE
DEHYDRATASE
CATABOLIC
(Salmonella
enterica) 		5 / 10 GLY A 185
ALA A 217
ILE A 183
SER A 219
ALA A 218
 LLP  A  58 ( 3.8A)
None
None
None
None
 1.14A 1utdT-2gn1A:
undetectable
1utdU-2gn1A:
undetectable		 1utdT-2gn1A:
11.99
1utdU-2gn1A:
11.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AVV_A_MK1A901_3
(POL POLYPROTEIN)		 2gn1 THREONINE
DEHYDRATASE
CATABOLIC
(Salmonella
enterica) 		6 / 12 GLY A 285
ALA A 284
ASP A 236
GLY A 184
ILE A 183
VAL A 261
 LLP  A  58 ( 4.8A)
LLP  A  58 ( 3.4A)
None
LLP  A  58 ( 3.5A)
None
None
 1.48A 2avvB-2gn1A:
undetectable		 2avvB-2gn1A:
15.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BM9_F_SAMF301_0
(CEPHALOSPORIN
HYDROXYLASE CMCI)		 2gn1 THREONINE
DEHYDRATASE
CATABOLIC
(Salmonella
enterica) 		5 / 12 GLY A  55
GLY A 237
ASP A 236
ALA A 284
ALA A 286
 None
LLP  A  58 ( 4.4A)
None
LLP  A  58 ( 3.4A)
None
 1.03A 2bm9F-2gn1A:
3.5		 2bm9F-2gn1A:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FN1_B_SALB503_1
(SALICYLATE
SYNTHETASE, IRP9)		 2gn1 THREONINE
DEHYDRATASE
CATABOLIC
(Salmonella
enterica) 		5 / 11 ILE A 266
GLY A 237
THR A 233
ARG A 319
GLU A 282
 None
LLP  A  58 ( 4.4A)
None
None
LLP  A  58 ( 3.7A)
 1.35A 2fn1B-2gn1A:
undetectable		 2fn1B-2gn1A:
24.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2H42_C_VIAC903_2
(CGMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE)		 2gn1 THREONINE
DEHYDRATASE
CATABOLIC
(Salmonella
enterica) 		3 / 3 ASN A 178
ILE A 309
MET A  30
 None
 0.76A 2h42C-2gn1A:
undetectable		 2h42C-2gn1A:
19.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IEN_B_017B402_1
(PROTEASE)		 2gn1 THREONINE
DEHYDRATASE
CATABOLIC
(Salmonella
enterica) 		6 / 12 GLY A 285
ALA A 284
ASP A 236
GLY A 184
ILE A 183
VAL A 261
 LLP  A  58 ( 4.8A)
LLP  A  58 ( 3.4A)
None
LLP  A  58 ( 3.5A)
None
None
 1.43A 2ienA-2gn1A:
undetectable		 2ienA-2gn1A:
15.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IEO_A_017A402_1
(PROTEASE)		 2gn1 THREONINE
DEHYDRATASE
CATABOLIC
(Salmonella
enterica) 		5 / 12 GLY A 283
ALA A 235
ASP A 236
ASP A 239
VAL A 208
 None
 0.93A 2ieoA-2gn1A:
undetectable		 2ieoA-2gn1A:
15.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q5K_A_AB1A201_1
(PROTEASE)		 2gn1 THREONINE
DEHYDRATASE
CATABOLIC
(Salmonella
enterica) 		5 / 9 ALA A 235
ASP A 236
GLY A 312
ILE A 310
VAL A 208
 None
None
LLP  A  58 ( 3.5A)
None
None
 1.03A 2q5kA-2gn1A:
undetectable		 2q5kA-2gn1A:
15.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2R5P_D_MK1D902_2
(PROTEASE)		 2gn1 THREONINE
DEHYDRATASE
CATABOLIC
(Salmonella
enterica) 		6 / 12 GLY A 285
ALA A 284
ASP A 236
GLY A 184
ILE A 183
VAL A 261
 LLP  A  58 ( 4.8A)
LLP  A  58 ( 3.4A)
None
LLP  A  58 ( 3.5A)
None
None
 1.46A 2r5pD-2gn1A:
undetectable		 2r5pD-2gn1A:
15.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2UXP_B_CLMB1211_0
(HTH-TYPE
TRANSCRIPTIONAL
REGULATOR TTGR)		 2gn1 THREONINE
DEHYDRATASE
CATABOLIC
(Salmonella
enterica) 		5 / 11 ALA A 284
GLU A 282
VAL A 208
GLY A 312
ILE A 310
 LLP  A  58 ( 3.4A)
LLP  A  58 ( 3.7A)
None
LLP  A  58 ( 3.5A)
None
 1.11A 2uxpB-2gn1A:
undetectable		 2uxpB-2gn1A:
21.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W9H_A_TOPA1160_1
(DIHYDROFOLATE
REDUCTASE)		 2gn1 THREONINE
DEHYDRATASE
CATABOLIC
(Salmonella
enterica) 		5 / 10 ALA A 286
LEU A 273
LEU A 293
SER A  33
ILE A  44
 None
 1.14A 2w9hA-2gn1A:
undetectable		 2w9hA-2gn1A:
19.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YDO_A_ADNA400_1
(ADENOSINE RECEPTOR
A2A)		 2gn1 THREONINE
DEHYDRATASE
CATABOLIC
(Salmonella
enterica) 		5 / 12 LEU A 293
LEU A  46
ASN A 277
ILE A 310
SER A 308
 None
 1.38A 2ydoA-2gn1A:
0.0		 2ydoA-2gn1A:
20.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Z54_A_AB1A200_2
(HIV-1 PROTEASE)		 2gn1 THREONINE
DEHYDRATASE
CATABOLIC
(Salmonella
enterica) 		6 / 12 GLY A 285
ALA A 284
ASP A 236
GLY A 184
ILE A 183
VAL A 261
 LLP  A  58 ( 4.8A)
LLP  A  58 ( 3.4A)
None
LLP  A  58 ( 3.5A)
None
None
 1.46A 2z54B-2gn1A:
undetectable		 2z54B-2gn1A:
15.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_E_SVRE510_2
(PHOSPHOLIPASE A2)		 2gn1 THREONINE
DEHYDRATASE
CATABOLIC
(Salmonella
enterica) 		4 / 6 VAL A  79
GLY A  61
ARG A  20
LEU A  21
 None
LLP  A  58 ( 4.2A)
None
None
 1.05A 3bjwE-2gn1A:
undetectable		 3bjwE-2gn1A:
15.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EM6_A_017A200_1
(PROTEASE)		 2gn1 THREONINE
DEHYDRATASE
CATABOLIC
(Salmonella
enterica) 		5 / 8 GLY A 285
ALA A 284
ASP A 236
GLY A 184
VAL A 261
 LLP  A  58 ( 4.8A)
LLP  A  58 ( 3.4A)
None
LLP  A  58 ( 3.5A)
None
 1.27A 3em6A-2gn1A:
undetectable		 3em6A-2gn1A:
15.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IV6_D_SAMD301_0
(PUTATIVE
ZN-DEPENDENT ALCOHOL
DEHYDROGENASE)		 2gn1 THREONINE
DEHYDRATASE
CATABOLIC
(Salmonella
enterica) 		5 / 12 GLY A 185
THR A 247
ASP A 239
ASP A 154
ARG A 242
 LLP  A  58 ( 3.8A)
None
None
None
None
 1.04A 3iv6D-2gn1A:
2.3		 3iv6D-2gn1A:
21.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NU9_A_478A401_2
(PROTEASE)		 2gn1 THREONINE
DEHYDRATASE
CATABOLIC
(Salmonella
enterica) 		6 / 10 GLY A 285
ALA A 284
ASP A 236
GLY A 184
ILE A 183
VAL A 261
 LLP  A  58 ( 4.8A)
LLP  A  58 ( 3.4A)
None
LLP  A  58 ( 3.5A)
None
None
 1.34A 3nu9B-2gn1A:
undetectable		 3nu9B-2gn1A:
15.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OY4_B_017B200_2
(HIV-1 PROTEASE)		 2gn1 THREONINE
DEHYDRATASE
CATABOLIC
(Salmonella
enterica) 		6 / 10 GLY A 285
ALA A 284
ASP A 236
GLY A 184
ILE A 183
VAL A 261
 LLP  A  58 ( 4.8A)
LLP  A  58 ( 3.4A)
None
LLP  A  58 ( 3.5A)
None
None
 1.47A 3oy4B-2gn1A:
undetectable		 3oy4B-2gn1A:
15.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PS9_A_SAMA670_0
(TRNA
5-METHYLAMINOMETHYL-
2-THIOURIDINE
BIOSYNTHESIS
BIFUNCTIONAL PROTEIN
MNMC)		 2gn1 THREONINE
DEHYDRATASE
CATABOLIC
(Salmonella
enterica) 		5 / 12 GLY A 313
ASN A  85
PHE A  48
ILE A 280
GLY A 285
 None
LLP  A  58 ( 3.8A)
None
None
LLP  A  58 ( 4.8A)
 1.23A 3ps9A-2gn1A:
4.4		 3ps9A-2gn1A:
18.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SO9_A_017A100_1
(HIV-1 PROTEASE)		 2gn1 THREONINE
DEHYDRATASE
CATABOLIC
(Salmonella
enterica) 		5 / 8 GLY A 285
ALA A 284
ASP A 236
GLY A 184
ILE A 183
 LLP  A  58 ( 4.8A)
LLP  A  58 ( 3.4A)
None
LLP  A  58 ( 3.5A)
None
 1.31A 3so9A-2gn1A:
undetectable		 3so9A-2gn1A:
15.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ACA_C_DXCC1478_0
(TRANSLATION
ELONGATION FACTOR
SELB)		 2gn1 THREONINE
DEHYDRATASE
CATABOLIC
(Salmonella
enterica) 		4 / 7 ASP A 316
GLY A 313
THR A 281
ILE A 280
 None
 0.81A 4acaC-2gn1A:
3.2		 4acaC-2gn1A:
23.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DQB_B_017B101_2
(ASPARTYL PROTEASE)		 2gn1 THREONINE
DEHYDRATASE
CATABOLIC
(Salmonella
enterica) 		6 / 10 GLY A 285
ALA A 284
ASP A 236
GLY A 184
ILE A 183
VAL A 261
 LLP  A  58 ( 4.8A)
LLP  A  58 ( 3.4A)
None
LLP  A  58 ( 3.5A)
None
None
 1.38A 4dqbB-2gn1A:
undetectable		 4dqbB-2gn1A:
14.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DQE_B_017B101_2
(ASPARTYL PROTEASE)		 2gn1 THREONINE
DEHYDRATASE
CATABOLIC
(Salmonella
enterica) 		6 / 10 GLY A 285
ALA A 284
ASP A 236
GLY A 184
ILE A 183
VAL A 261
 LLP  A  58 ( 4.8A)
LLP  A  58 ( 3.4A)
None
LLP  A  58 ( 3.5A)
None
None
 1.36A 4dqeB-2gn1A:
undetectable		 4dqeB-2gn1A:
14.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DQH_B_017B101_2
(WILD-TYPE HIV-1
PROTEASE DIMER)		 2gn1 THREONINE
DEHYDRATASE
CATABOLIC
(Salmonella
enterica) 		6 / 10 GLY A 285
ALA A 284
ASP A 236
GLY A 184
ILE A 183
VAL A 261
 LLP  A  58 ( 4.8A)
LLP  A  58 ( 3.4A)
None
LLP  A  58 ( 3.5A)
None
None
 1.38A 4dqhB-2gn1A:
undetectable		 4dqhB-2gn1A:
15.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K50_A_ACTA502_0
(RNA POLYMERASE
3D-POL)		 2gn1 THREONINE
DEHYDRATASE
CATABOLIC
(Salmonella
enterica) 		3 / 3 ARG A  20
LYS A  65
LYS A 157
 None
 0.95A 4k50A-2gn1A:
undetectable		 4k50A-2gn1A:
21.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K50_E_ACTE502_0
(RNA POLYMERASE
3D-POL)		 2gn1 THREONINE
DEHYDRATASE
CATABOLIC
(Salmonella
enterica) 		3 / 3 ARG A  20
LYS A  65
LYS A 157
 None
 0.91A 4k50E-2gn1A:
undetectable		 4k50E-2gn1A:
21.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K50_I_ACTI506_0
(RNA POLYMERASE
3D-POL)		 2gn1 THREONINE
DEHYDRATASE
CATABOLIC
(Salmonella
enterica) 		3 / 3 ARG A  20
LYS A  65
LYS A 157
 None
 0.97A 4k50I-2gn1A:
undetectable		 4k50I-2gn1A:
21.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Q1X_A_017A101_1
(ASPARTYL PROTEASE)		 2gn1 THREONINE
DEHYDRATASE
CATABOLIC
(Salmonella
enterica) 		6 / 11 GLY A 285
ALA A 284
ASP A 236
GLY A 184
ILE A 183
VAL A 261
 LLP  A  58 ( 4.8A)
LLP  A  58 ( 3.4A)
None
LLP  A  58 ( 3.5A)
None
None
 1.44A 4q1xA-2gn1A:
undetectable		 4q1xA-2gn1A:
15.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Q1Y_A_017A106_1
(ASPARTYL PROTEASE)		 2gn1 THREONINE
DEHYDRATASE
CATABOLIC
(Salmonella
enterica) 		6 / 10 GLY A 285
ALA A 284
ASP A 236
GLY A 184
ILE A 183
VAL A 261
 LLP  A  58 ( 4.8A)
LLP  A  58 ( 3.4A)
None
LLP  A  58 ( 3.5A)
None
None
 1.44A 4q1yA-2gn1A:
undetectable		 4q1yA-2gn1A:
15.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QZU_C_ACTC202_0
(RETINOL-BINDING
PROTEIN 2)		 2gn1 THREONINE
DEHYDRATASE
CATABOLIC
(Salmonella
enterica) 		4 / 6 GLU A  49
THR A  28
GLN A  52
LEU A  21
 None
 1.37A 4qzuC-2gn1A:
undetectable		 4qzuC-2gn1A:
16.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R1Z_A_AERA601_1
(CYP17A1 PROTEIN)		 2gn1 THREONINE
DEHYDRATASE
CATABOLIC
(Salmonella
enterica) 		5 / 9 ALA A  87
ILE A 141
GLY A 101
ALA A 122
VAL A 125
 None
 0.94A 4r1zA-2gn1A:
undetectable		 4r1zA-2gn1A:
22.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R21_B_STRB601_1
(CYTOCHROME P450
FAMILY 17
POLYPEPTIDE 2)		 2gn1 THREONINE
DEHYDRATASE
CATABOLIC
(Salmonella
enterica) 		5 / 9 ILE A 250
VAL A 251
GLY A 191
ILE A 203
VAL A 255
 None
 1.07A 4r21B-2gn1A:
undetectable		 4r21B-2gn1A:
22.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z2E_F_TR6F101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT B
SYMMETRIZED E-SITE
DNA)		 2gn1 THREONINE
DEHYDRATASE
CATABOLIC
(Salmonella
enterica) 		4 / 5 GLY A  77
ARG A 147
GLY A 146
GLU A 145
 None
 1.19A 4z2eB-2gn1A:
undetectable
4z2eC-2gn1A:
undetectable		 4z2eB-2gn1A:
23.17
4z2eC-2gn1A:
25.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5C0O_F_SAMF301_0
(TRNA
(ADENINE(58)-N(1))-M
ETHYLTRANSFERASE
TRMI)		 2gn1 THREONINE
DEHYDRATASE
CATABOLIC
(Salmonella
enterica) 		5 / 12 GLY A 184
GLY A 186
GLY A 187
LEU A 188
ALA A 210
 LLP  A  58 ( 3.5A)
LLP  A  58 ( 3.4A)
LLP  A  58 ( 3.2A)
LLP  A  58 ( 4.5A)
None
 0.65A 5c0oF-2gn1A:
undetectable		 5c0oF-2gn1A:
20.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_P_TRPP101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2gn1 THREONINE
DEHYDRATASE
CATABOLIC
(Salmonella
enterica) 		5 / 10 GLY A 184
ALA A 217
ILE A 183
SER A 219
ALA A 218
 LLP  A  58 ( 3.5A)
None
None
None
None
 1.14A 5eeuO-2gn1A:
undetectable
5eeuP-2gn1A:
undetectable		 5eeuO-2gn1A:
11.99
5eeuP-2gn1A:
11.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_P_TRPP101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2gn1 THREONINE
DEHYDRATASE
CATABOLIC
(Salmonella
enterica) 		5 / 10 GLY A 185
ALA A 217
ILE A 183
SER A 219
ALA A 218
 LLP  A  58 ( 3.8A)
None
None
None
None
 1.14A 5eeuO-2gn1A:
undetectable
5eeuP-2gn1A:
undetectable		 5eeuO-2gn1A:
11.99
5eeuP-2gn1A:
11.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_R_TRPR101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2gn1 THREONINE
DEHYDRATASE
CATABOLIC
(Salmonella
enterica) 		5 / 10 GLY A 184
ALA A 217
ILE A 183
SER A 219
ALA A 218
 LLP  A  58 ( 3.5A)
None
None
None
None
 1.14A 5eeuQ-2gn1A:
undetectable
5eeuR-2gn1A:
undetectable		 5eeuQ-2gn1A:
11.99
5eeuR-2gn1A:
11.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_R_TRPR101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2gn1 THREONINE
DEHYDRATASE
CATABOLIC
(Salmonella
enterica) 		5 / 10 GLY A 185
ALA A 217
ILE A 183
SER A 219
ALA A 218
 LLP  A  58 ( 3.8A)
None
None
None
None
 1.15A 5eeuQ-2gn1A:
undetectable
5eeuR-2gn1A:
undetectable		 5eeuQ-2gn1A:
11.99
5eeuR-2gn1A:
11.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_P_TRPP101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2gn1 THREONINE
DEHYDRATASE
CATABOLIC
(Salmonella
enterica) 		5 / 10 GLY A 184
ALA A 217
ILE A 183
SER A 219
ALA A 218
 LLP  A  58 ( 3.5A)
None
None
None
None
 1.14A 5eevO-2gn1A:
undetectable
5eevP-2gn1A:
undetectable		 5eevO-2gn1A:
11.99
5eevP-2gn1A:
11.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_P_TRPP101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2gn1 THREONINE
DEHYDRATASE
CATABOLIC
(Salmonella
enterica) 		5 / 10 GLY A 185
ALA A 217
ILE A 183
SER A 219
ALA A 218
 LLP  A  58 ( 3.8A)
None
None
None
None
 1.14A 5eevO-2gn1A:
undetectable
5eevP-2gn1A:
undetectable		 5eevO-2gn1A:
11.99
5eevP-2gn1A:
11.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_R_TRPR101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2gn1 THREONINE
DEHYDRATASE
CATABOLIC
(Salmonella
enterica) 		5 / 10 GLY A 184
ALA A 217
ILE A 183
SER A 219
ALA A 218
 LLP  A  58 ( 3.5A)
None
None
None
None
 1.14A 5eevQ-2gn1A:
undetectable
5eevR-2gn1A:
undetectable		 5eevQ-2gn1A:
11.99
5eevR-2gn1A:
11.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_R_TRPR101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2gn1 THREONINE
DEHYDRATASE
CATABOLIC
(Salmonella
enterica) 		5 / 10 GLY A 185
ALA A 217
ILE A 183
SER A 219
ALA A 218
 LLP  A  58 ( 3.8A)
None
None
None
None
 1.14A 5eevQ-2gn1A:
undetectable
5eevR-2gn1A:
undetectable		 5eevQ-2gn1A:
11.99
5eevR-2gn1A:
11.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_P_TRPP101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2gn1 THREONINE
DEHYDRATASE
CATABOLIC
(Salmonella
enterica) 		5 / 10 GLY A 184
ALA A 217
ILE A 183
SER A 219
ALA A 218
 LLP  A  58 ( 3.5A)
None
None
None
None
 1.14A 5eewO-2gn1A:
undetectable
5eewP-2gn1A:
undetectable		 5eewO-2gn1A:
11.99
5eewP-2gn1A:
11.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_P_TRPP101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2gn1 THREONINE
DEHYDRATASE
CATABOLIC
(Salmonella
enterica) 		5 / 10 GLY A 185
ALA A 217
ILE A 183
SER A 219
ALA A 218
 LLP  A  58 ( 3.8A)
None
None
None
None
 1.14A 5eewO-2gn1A:
undetectable
5eewP-2gn1A:
undetectable		 5eewO-2gn1A:
11.99
5eewP-2gn1A:
11.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_R_TRPR101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2gn1 THREONINE
DEHYDRATASE
CATABOLIC
(Salmonella
enterica) 		5 / 10 GLY A 184
ALA A 217
ILE A 183
SER A 219
ALA A 218
 LLP  A  58 ( 3.5A)
None
None
None
None
 1.14A 5eewQ-2gn1A:
undetectable
5eewR-2gn1A:
undetectable		 5eewQ-2gn1A:
11.99
5eewR-2gn1A:
11.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_R_TRPR101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2gn1 THREONINE
DEHYDRATASE
CATABOLIC
(Salmonella
enterica) 		5 / 10 GLY A 185
ALA A 217
ILE A 183
SER A 219
ALA A 218
 LLP  A  58 ( 3.8A)
None
None
None
None
 1.14A 5eewQ-2gn1A:
undetectable
5eewR-2gn1A:
undetectable		 5eewQ-2gn1A:
11.99
5eewR-2gn1A:
11.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_P_TRPP101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2gn1 THREONINE
DEHYDRATASE
CATABOLIC
(Salmonella
enterica) 		5 / 10 GLY A 184
ALA A 217
ILE A 183
SER A 219
ALA A 218
 LLP  A  58 ( 3.5A)
None
None
None
None
 1.14A 5eexO-2gn1A:
undetectable
5eexP-2gn1A:
undetectable		 5eexO-2gn1A:
11.99
5eexP-2gn1A:
11.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_P_TRPP101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2gn1 THREONINE
DEHYDRATASE
CATABOLIC
(Salmonella
enterica) 		5 / 10 GLY A 185
ALA A 217
ILE A 183
SER A 219
ALA A 218
 LLP  A  58 ( 3.8A)
None
None
None
None
 1.14A 5eexO-2gn1A:
undetectable
5eexP-2gn1A:
undetectable		 5eexO-2gn1A:
11.99
5eexP-2gn1A:
11.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_P_TRPP101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2gn1 THREONINE
DEHYDRATASE
CATABOLIC
(Salmonella
enterica) 		5 / 10 GLY A 184
ALA A 217
ILE A 183
SER A 219
ALA A 218
 LLP  A  58 ( 3.5A)
None
None
None
None
 1.14A 5eeyO-2gn1A:
undetectable
5eeyP-2gn1A:
undetectable		 5eeyO-2gn1A:
11.99
5eeyP-2gn1A:
11.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_P_TRPP101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2gn1 THREONINE
DEHYDRATASE
CATABOLIC
(Salmonella
enterica) 		5 / 10 GLY A 185
ALA A 217
ILE A 183
SER A 219
ALA A 218
 LLP  A  58 ( 3.8A)
None
None
None
None
 1.14A 5eeyO-2gn1A:
undetectable
5eeyP-2gn1A:
undetectable		 5eeyO-2gn1A:
11.99
5eeyP-2gn1A:
11.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_P_TRPP101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2gn1 THREONINE
DEHYDRATASE
CATABOLIC
(Salmonella
enterica) 		5 / 10 GLY A 184
ALA A 217
ILE A 183
SER A 219
ALA A 218
 LLP  A  58 ( 3.5A)
None
None
None
None
 1.14A 5eezO-2gn1A:
undetectable
5eezP-2gn1A:
undetectable		 5eezO-2gn1A:
11.99
5eezP-2gn1A:
11.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_P_TRPP101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2gn1 THREONINE
DEHYDRATASE
CATABOLIC
(Salmonella
enterica) 		5 / 10 GLY A 185
ALA A 217
ILE A 183
SER A 219
ALA A 218
 LLP  A  58 ( 3.8A)
None
None
None
None
 1.14A 5eezO-2gn1A:
undetectable
5eezP-2gn1A:
undetectable		 5eezO-2gn1A:
11.99
5eezP-2gn1A:
11.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_P_TRPP101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2gn1 THREONINE
DEHYDRATASE
CATABOLIC
(Salmonella
enterica) 		5 / 10 GLY A 184
ALA A 217
ILE A 183
SER A 219
ALA A 218
 LLP  A  58 ( 3.5A)
None
None
None
None
 1.14A 5ef0O-2gn1A:
undetectable
5ef0P-2gn1A:
undetectable		 5ef0O-2gn1A:
11.99
5ef0P-2gn1A:
11.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_P_TRPP101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2gn1 THREONINE
DEHYDRATASE
CATABOLIC
(Salmonella
enterica) 		5 / 10 GLY A 185
ALA A 217
ILE A 183
SER A 219
ALA A 218
 LLP  A  58 ( 3.8A)
None
None
None
None
 1.14A 5ef0O-2gn1A:
undetectable
5ef0P-2gn1A:
undetectable		 5ef0O-2gn1A:
11.99
5ef0P-2gn1A:
11.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_P_TRPP101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2gn1 THREONINE
DEHYDRATASE
CATABOLIC
(Salmonella
enterica) 		5 / 10 GLY A 184
ALA A 217
ILE A 183
SER A 219
ALA A 218
 LLP  A  58 ( 3.5A)
None
None
None
None
 1.14A 5ef1O-2gn1A:
undetectable
5ef1P-2gn1A:
undetectable		 5ef1O-2gn1A:
11.99
5ef1P-2gn1A:
11.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_P_TRPP101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2gn1 THREONINE
DEHYDRATASE
CATABOLIC
(Salmonella
enterica) 		5 / 10 GLY A 185
ALA A 217
ILE A 183
SER A 219
ALA A 218
 LLP  A  58 ( 3.8A)
None
None
None
None
 1.14A 5ef1O-2gn1A:
undetectable
5ef1P-2gn1A:
undetectable		 5ef1O-2gn1A:
11.99
5ef1P-2gn1A:
11.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_P_TRPP101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2gn1 THREONINE
DEHYDRATASE
CATABOLIC
(Salmonella
enterica) 		5 / 10 GLY A 184
ALA A 217
ILE A 183
SER A 219
ALA A 218
 LLP  A  58 ( 3.5A)
None
None
None
None
 1.14A 5ef2O-2gn1A:
undetectable
5ef2P-2gn1A:
undetectable		 5ef2O-2gn1A:
11.99
5ef2P-2gn1A:
11.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_P_TRPP101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2gn1 THREONINE
DEHYDRATASE
CATABOLIC
(Salmonella
enterica) 		5 / 10 GLY A 185
ALA A 217
ILE A 183
SER A 219
ALA A 218
 LLP  A  58 ( 3.8A)
None
None
None
None
 1.14A 5ef2O-2gn1A:
undetectable
5ef2P-2gn1A:
undetectable		 5ef2O-2gn1A:
11.99
5ef2P-2gn1A:
11.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_P_TRPP101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2gn1 THREONINE
DEHYDRATASE
CATABOLIC
(Salmonella
enterica) 		5 / 10 GLY A 184
ALA A 217
ILE A 183
SER A 219
ALA A 218
 LLP  A  58 ( 3.5A)
None
None
None
None
 1.14A 5ef3O-2gn1A:
undetectable
5ef3P-2gn1A:
undetectable		 5ef3O-2gn1A:
11.99
5ef3P-2gn1A:
11.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_P_TRPP101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2gn1 THREONINE
DEHYDRATASE
CATABOLIC
(Salmonella
enterica) 		5 / 10 GLY A 185
ALA A 217
ILE A 183
SER A 219
ALA A 218
 LLP  A  58 ( 3.8A)
None
None
None
None
 1.14A 5ef3O-2gn1A:
undetectable
5ef3P-2gn1A:
undetectable		 5ef3O-2gn1A:
11.99
5ef3P-2gn1A:
11.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IFU_A_GBMA801_1
(PROLINE--TRNA LIGASE)		 2gn1 THREONINE
DEHYDRATASE
CATABOLIC
(Salmonella
enterica) 		5 / 12 LEU A 188
ILE A 165
GLY A 166
ILE A 169
MET A 170
 LLP  A  58 ( 4.5A)
None
None
None
None
 1.13A 5ifuA-2gn1A:
undetectable		 5ifuA-2gn1A:
23.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JWA_H_ACTH614_0
(NADH DEHYDROGENASE,
PUTATIVE)		 2gn1 THREONINE
DEHYDRATASE
CATABOLIC
(Salmonella
enterica) 		4 / 6 ILE A 180
VAL A 261
VAL A 208
SER A 294
 None
 1.00A 5jwaH-2gn1A:
2.0		 5jwaH-2gn1A:
23.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KR0_A_478A101_2
(PROTEASE E35D-APV)		 2gn1 THREONINE
DEHYDRATASE
CATABOLIC
(Salmonella
enterica) 		6 / 9 GLY A 285
ALA A 284
ASP A 236
GLY A 184
ILE A 183
VAL A 261
 LLP  A  58 ( 4.8A)
LLP  A  58 ( 3.4A)
None
LLP  A  58 ( 3.5A)
None
None
 1.31A 5kr0B-2gn1A:
undetectable		 5kr0B-2gn1A:
15.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WWS_B_SAMB501_0
(PUTATIVE
METHYLTRANSFERASE
NSUN6)		 2gn1 THREONINE
DEHYDRATASE
CATABOLIC
(Salmonella
enterica) 		5 / 12 ALA A 160
LYS A  65
ILE A 194
GLY A 186
ASP A 155
 None
None
None
LLP  A  58 ( 3.4A)
None
 1.09A 5wwsB-2gn1A:
2.5		 5wwsB-2gn1A:
21.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DJ2_B_AB1B201_0
(HIV-1 PROTEASE)		 2gn1 THREONINE
DEHYDRATASE
CATABOLIC
(Salmonella
enterica) 		5 / 10 ALA A 235
ASP A 236
GLY A 312
ILE A 310
VAL A 208
 None
None
LLP  A  58 ( 3.5A)
None
None
 0.98A 6dj2A-2gn1A:
undetectable		 6dj2A-2gn1A:
14.24