SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2go0'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PH9_A_GNTA301_1
(SOLUBLE
ACETYLCHOLINE
RECEPTOR)		 2go0 REGENERATING
ISLET-DERIVED
PROTEIN 3 ALPHA
(Homo
sapiens) 		4 / 7 TYR A  92
TRP A 120
TYR A   9
ILE A  66
 None
 1.10A 2ph9A-2go0A:
undetectable
2ph9B-2go0A:
undetectable		 2ph9A-2go0A:
19.66
2ph9B-2go0A:
19.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XDC_A_DVAA8_0
(GRAMICIDIN A)		 2go0 REGENERATING
ISLET-DERIVED
PROTEIN 3 ALPHA
(Homo
sapiens) 		3 / 3 VAL A 132
TRP A  23
TRP A  65
 None
 1.26A 2xdcA-2go0A:
undetectable
2xdcB-2go0A:
undetectable		 2xdcA-2go0A:
9.41
2xdcB-2go0A:
9.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XDC_B_DVAB8_0
(GRAMICIDIN A)		 2go0 REGENERATING
ISLET-DERIVED
PROTEIN 3 ALPHA
(Homo
sapiens) 		3 / 3 TRP A  65
VAL A 132
TRP A  23
 None
 1.28A 2xdcA-2go0A:
undetectable
2xdcB-2go0A:
undetectable		 2xdcA-2go0A:
9.41
2xdcB-2go0A:
9.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XDC_D_DVAD8_0
(GRAMICIDIN A)		 2go0 REGENERATING
ISLET-DERIVED
PROTEIN 3 ALPHA
(Homo
sapiens) 		3 / 3 TRP A  65
VAL A 132
TRP A  23
 None
 0.87A 2xdcC-2go0A:
undetectable
2xdcD-2go0A:
undetectable		 2xdcC-2go0A:
9.41
2xdcD-2go0A:
9.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XDC_F_DVAF8_0
(GRAMICIDIN A)		 2go0 REGENERATING
ISLET-DERIVED
PROTEIN 3 ALPHA
(Homo
sapiens) 		3 / 3 TRP A  65
VAL A 132
TRP A  23
 None
 0.90A 2xdcE-2go0A:
undetectable
2xdcF-2go0A:
undetectable		 2xdcE-2go0A:
9.41
2xdcF-2go0A:
9.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y5M_A_DVAA8_0
(VAL-GRAMICIDIN A)		 2go0 REGENERATING
ISLET-DERIVED
PROTEIN 3 ALPHA
(Homo
sapiens) 		3 / 3 VAL A 132
TRP A  23
TRP A  65
 None
 1.26A 2y5mA-2go0A:
undetectable
2y5mB-2go0A:
undetectable		 2y5mA-2go0A:
9.41
2y5mB-2go0A:
9.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y5M_F_DVAF8_0
(VAL-GRAMICIDIN A)		 2go0 REGENERATING
ISLET-DERIVED
PROTEIN 3 ALPHA
(Homo
sapiens) 		3 / 3 TRP A  65
VAL A 132
TRP A  23
 None
 0.88A 2y5mE-2go0A:
undetectable
2y5mF-2go0A:
undetectable		 2y5mE-2go0A:
9.41
2y5mF-2go0A:
9.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y6N_A_DVAA8_0
(VAL-GRAMICIDIN A)		 2go0 REGENERATING
ISLET-DERIVED
PROTEIN 3 ALPHA
(Homo
sapiens) 		3 / 3 VAL A 132
TRP A  23
TRP A  65
 None
 1.26A 2y6nA-2go0A:
undetectable
2y6nB-2go0A:
undetectable		 2y6nA-2go0A:
9.41
2y6nB-2go0A:
9.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y6N_B_DVAB8_0
(VAL-GRAMICIDIN A)		 2go0 REGENERATING
ISLET-DERIVED
PROTEIN 3 ALPHA
(Homo
sapiens) 		3 / 3 TRP A  65
VAL A 132
TRP A  23
 None
 1.27A 2y6nA-2go0A:
undetectable
2y6nB-2go0A:
undetectable		 2y6nA-2go0A:
9.41
2y6nB-2go0A:
9.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y6N_D_DVAD8_0
(VAL-GRAMICIDIN A)		 2go0 REGENERATING
ISLET-DERIVED
PROTEIN 3 ALPHA
(Homo
sapiens) 		3 / 3 TRP A  65
VAL A 132
TRP A  23
 None
 0.86A 2y6nC-2go0A:
undetectable
2y6nD-2go0A:
undetectable		 2y6nC-2go0A:
9.41
2y6nD-2go0A:
9.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y6N_F_DVAF8_0
(VAL-GRAMICIDIN A)		 2go0 REGENERATING
ISLET-DERIVED
PROTEIN 3 ALPHA
(Homo
sapiens) 		3 / 3 TRP A  65
VAL A 132
TRP A  23
 None
 0.86A 2y6nE-2go0A:
undetectable
2y6nF-2go0A:
undetectable		 2y6nE-2go0A:
9.41
2y6nF-2go0A:
9.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ZQ8_A_DVAA8_0
(VAL-GRAMICIDIN A)		 2go0 REGENERATING
ISLET-DERIVED
PROTEIN 3 ALPHA
(Homo
sapiens) 		3 / 3 VAL A 132
TRP A  23
TRP A  65
 None
 1.30A 3zq8A-2go0A:
undetectable
3zq8B-2go0A:
undetectable		 3zq8A-2go0A:
9.41
3zq8B-2go0A:
9.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EMA_A_BRLA601_2
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 2go0 REGENERATING
ISLET-DERIVED
PROTEIN 3 ALPHA
(Homo
sapiens) 		3 / 3 PHE A  49
VAL A  64
ILE A  66
 None
 0.49A 4emaA-2go0A:
undetectable		 4emaA-2go0A:
20.31