SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2go2'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z95_A_198A501_2
(ANDROGEN RECEPTOR)		 2go2 KUNITZ-TYPE SERINE
PROTEASE INHIBITOR
BBKI
(Bauhinia
bauhinioides) 		4 / 6 LEU A  63
ASN A  14
LEU A 109
ILE A  76
 None
EDO  A 700 (-3.3A)
None
None
 0.91A 1z95A-2go2A:
undetectable		 1z95A-2go2A:
18.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F8L_A_SAMA400_0
(HYPOTHETICAL PROTEIN
LMO1582)		 2go2 KUNITZ-TYPE SERINE
PROTEASE INHIBITOR
BBKI
(Bauhinia
bauhinioides) 		5 / 12 HIS A  51
GLY A  30
VAL A  46
ASP A  48
PHE A  78
 None
 1.06A 2f8lA-2go2A:
undetectable		 2f8lA-2go2A:
19.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PLW_A_SAMA203_1
(RIBOSOMAL RNA
METHYLTRANSFERASE,
PUTATIVE)		 2go2 KUNITZ-TYPE SERINE
PROTEASE INHIBITOR
BBKI
(Bauhinia
bauhinioides) 		3 / 3 SER A 107
ASP A 104
ASP A  89
 None
 0.59A 2plwA-2go2A:
undetectable		 2plwA-2go2A:
24.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A9K_A_TYLA2200_1
(CREB-BINDING PROTEIN)		 2go2 KUNITZ-TYPE SERINE
PROTEASE INHIBITOR
BBKI
(Bauhinia
bauhinioides) 		4 / 6 VAL A 114
LEU A  74
ILE A  76
VAL A  12
 None
 0.87A 4a9kA-2go2A:
undetectable		 4a9kA-2go2A:
21.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OKW_A_198A1001_2
(ANDROGEN RECEPTOR)		 2go2 KUNITZ-TYPE SERINE
PROTEASE INHIBITOR
BBKI
(Bauhinia
bauhinioides) 		4 / 7 LEU A  63
ASN A  14
LEU A 109
ILE A  76
 None
EDO  A 700 (-3.3A)
None
None
 0.92A 4okwA-2go2A:
undetectable		 4okwA-2go2A:
18.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Y9M_A_NIOA401_1
(CASEIN KINASE II
SUBUNIT ALPHA')		 2go2 KUNITZ-TYPE SERINE
PROTEASE INHIBITOR
BBKI
(Bauhinia
bauhinioides) 		4 / 8 LEU A 147
VAL A 100
VAL A  45
ILE A  76
 None
 0.69A 5y9mA-2go2A:
undetectable		 5y9mA-2go2A:
21.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Y9M_X_NIOX401_1
(CASEIN KINASE II
SUBUNIT ALPHA')		 2go2 KUNITZ-TYPE SERINE
PROTEASE INHIBITOR
BBKI
(Bauhinia
bauhinioides) 		4 / 8 LEU A 147
VAL A 100
VAL A  45
ILE A  76
 None
 0.70A 5y9mX-2go2A:
undetectable		 5y9mX-2go2A:
21.94