SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2go9'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5QGK_A_ACTA301_0 (PEROXISOMAL COENZYME A DIPHOSPHATASE NUDT7)	2go9	U4/U6 SNRNA-ASSOCIATED SPLICING FACTOR PRP24 (Saccharomyces cerevisiae)	3 / 3	VAL A 34 TYR A 22 GLN A 18	None	0.73A	5qgkA-2go9A: undetectable	5qgkA-2go9A: 23.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5QGR_A_ACTA301_0 (PEROXISOMAL COENZYME A DIPHOSPHATASE NUDT7)	2go9	U4/U6 SNRNA-ASSOCIATED SPLICING FACTOR PRP24 (Saccharomyces cerevisiae)	3 / 3	VAL A 34 TYR A 22 GLN A 18	None	0.69A	5qgrA-2go9A: undetectable	5qgrA-2go9A: 23.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5QGT_A_ACTA301_0 (PEROXISOMAL COENZYME A DIPHOSPHATASE NUDT7)	2go9	U4/U6 SNRNA-ASSOCIATED SPLICING FACTOR PRP24 (Saccharomyces cerevisiae)	3 / 3	VAL A 34 TYR A 22 GLN A 18	None	0.67A	5qgtA-2go9A: undetectable	5qgtA-2go9A: 23.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5X5Q_D_D16D402_1 (THYMIDYLATE SYNTHASE)	2go9	U4/U6 SNRNA-ASSOCIATED SPLICING FACTOR PRP24 (Saccharomyces cerevisiae)	4 / 8	LYS A 63 PHE A 25 ASP A 55 GLY A 56	None	0.69A	5x5qD-2go9A: undetectable	5x5qD-2go9A: 19.38

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["5QGK_A_ACTA301_0","PEROXISOMAL COENZYME A DIPHOSPHATASE NUDT7","2go9","U4\/U6 SNRNA-ASSOCIATED SPLICING FACTOR PRP24","Saccharomyces cerevisiae",3,"VAL A  34;TYR A  22;GLN A  18","None","0.73A","5qgkA-2go9A:undetectable","5qgkA-2go9A:23.04"],["5QGR_A_ACTA301_0","PEROXISOMAL COENZYME A DIPHOSPHATASE NUDT7","2go9","U4\/U6 SNRNA-ASSOCIATED SPLICING FACTOR PRP24","Saccharomyces cerevisiae",3,"VAL A  34;TYR A  22;GLN A  18","None","0.69A","5qgrA-2go9A:undetectable","5qgrA-2go9A:23.04"],["5QGT_A_ACTA301_0","PEROXISOMAL COENZYME A DIPHOSPHATASE NUDT7","2go9","U4\/U6 SNRNA-ASSOCIATED SPLICING FACTOR PRP24","Saccharomyces cerevisiae",3,"VAL A  34;TYR A  22;GLN A  18","None","0.67A","5qgtA-2go9A:undetectable","5qgtA-2go9A:23.04"],["5X5Q_D_D16D402_1","THYMIDYLATE SYNTHASE","2go9","U4\/U6 SNRNA-ASSOCIATED SPLICING FACTOR PRP24","Saccharomyces cerevisiae",4,"LYS A  63;PHE A  25;ASP A  55;GLY A  56","None","0.69A","5x5qD-2go9A:undetectable","5x5qD-2go9A:19.38"]]