SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2goj'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A51_D_VDYD6178_1
(VITAMIN D
HYDROXYLASE)		 2goj FE-SUPEROXIDE
DISMUTASE
(Plasmodium
falciparum) 		5 / 12 ILE A  96
MET A 195
ILE A 153
VAL A 182
PRO A  88
 None
 1.10A 3a51D-2gojA:
undetectable		 3a51D-2gojA:
15.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A51_E_VDYE6178_1
(VITAMIN D
HYDROXYLASE)		 2goj FE-SUPEROXIDE
DISMUTASE
(Plasmodium
falciparum) 		5 / 12 ILE A  96
MET A 195
ILE A 153
VAL A 182
PRO A  88
 None
 1.17A 3a51E-2gojA:
undetectable		 3a51E-2gojA:
15.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K8M_B_ACRB820_1
(ALPHA-AMYLASE, SUSG)		 2goj FE-SUPEROXIDE
DISMUTASE
(Plasmodium
falciparum) 		4 / 7 GLU A  87
TRP A 184
LEU A 154
TRP A 178
 None
 1.37A 3k8mB-2gojA:
undetectable		 3k8mB-2gojA:
15.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DSG_A_0HKA1201_1
(MUSCARINIC
ACETYLCHOLINE
RECEPTOR
M4,ENDOLYSIN,ENDOLYS
IN,MUSCARINIC
ACETYLCHOLINE
RECEPTOR M4)		 2goj FE-SUPEROXIDE
DISMUTASE
(Plasmodium
falciparum) 		5 / 12 TYR A  76
SER A  79
TRP A  77
THR A  22
TYR A 174
 None
 1.50A 5dsgA-2gojA:
undetectable		 5dsgA-2gojA:
18.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HUO_D_08HD501_0
(GAMMA-AMINOBUTYRIC
ACID RECEPTOR
SUBUNIT
ALPHA-1,GAMMA-AMINOB
UTYRIC ACID RECEPTOR
SUBUNIT ALPHA-1
GAMMA-AMINOBUTYRIC
ACID RECEPTOR
SUBUNIT GAMMA-2)		 2goj FE-SUPEROXIDE
DISMUTASE
(Plasmodium
falciparum) 		4 / 8 TYR A  76
PHE A 110
VAL A 182
SER A  79
 None
 1.05A 6huoC-2gojA:
undetectable
6huoD-2gojA:
undetectable		 6huoC-2gojA:
16.67
6huoD-2gojA:
15.74