SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2goy'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HVY_C_D16C416_1
(THYMIDYLATE SYNTHASE)		 2goy ADENOSINE
PHOSPHOSULFATE
REDUCTASE
(Pseudomonas
aeruginosa) 		5 / 11 PHE A 193
ILE A  45
LEU A  69
GLY A 161
MET A  72
 None
 1.13A 1hvyC-2goyA:
undetectable		 1hvyC-2goyA:
23.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JJP_A_KLNA413_1
(CYTOCHROME P450
113A1)		 2goy ADENOSINE
PHOSPHOSULFATE
REDUCTASE
(Pseudomonas
aeruginosa) 		5 / 12 ALA A  34
LEU A  37
ALA A  38
GLN A 166
GLN A 162
 None
 1.29A 2jjpA-2goyA:
undetectable		 2jjpA-2goyA:
22.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OLT_B_GCSB302_1
(CHITOSANASE)		 2goy ADENOSINE
PHOSPHOSULFATE
REDUCTASE
(Pseudomonas
aeruginosa) 		4 / 5 ARG A  89
THR A  87
ASP A  86
TYR A  95
 None
SF4  A 301 ( 4.1A)
None
None
 1.44A 4oltB-2goyA:
undetectable		 4oltB-2goyA:
21.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QWP_A_GCSA302_1
(CHITOSANASE)		 2goy ADENOSINE
PHOSPHOSULFATE
REDUCTASE
(Pseudomonas
aeruginosa) 		4 / 5 ARG A  89
THR A  87
ASP A  86
TYR A  95
 None
SF4  A 301 ( 4.1A)
None
None
 1.47A 4qwpA-2goyA:
undetectable		 4qwpA-2goyA:
21.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EML_A_SAMA701_0
(PROTEIN ARGININE
N-METHYLTRANSFERASE
5)		 2goy ADENOSINE
PHOSPHOSULFATE
REDUCTASE
(Pseudomonas
aeruginosa) 		5 / 12 PRO A 230
GLY A  88
PRO A 114
LEU A 119
LEU A 128
 SF4  A 301 ( 4.6A)
None
None
None
None
 1.20A 5emlA-2goyA:
3.3		 5emlA-2goyA:
18.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ODI_D_ACTD202_0
(METHYL-VIOLOGEN
REDUCING
HYDROGENASE, SUBUNIT
D)		 2goy ADENOSINE
PHOSPHOSULFATE
REDUCTASE
(Pseudomonas
aeruginosa) 		3 / 3 HIS A 219
GLU A  65
TRP A 205
 None
 1.24A 5odiD-2goyA:
undetectable		 5odiD-2goyA:
19.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5SYF_B_TA1B502_1
(TUBULIN BETA CHAIN)		 2goy ADENOSINE
PHOSPHOSULFATE
REDUCTASE
(Pseudomonas
aeruginosa) 		5 / 12 ASP A  44
ALA A  49
ARG A  78
PRO A 195
LEU A  69
 None
 1.26A 5syfB-2goyA:
2.2		 5syfB-2goyA:
18.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5SYF_B_TA1B502_1
(TUBULIN BETA CHAIN)		 2goy ADENOSINE
PHOSPHOSULFATE
REDUCTASE
(Pseudomonas
aeruginosa) 		5 / 12 ASP A  44
LEU A 213
ALA A  73
PRO A 195
LEU A 196
 None
 1.21A 5syfB-2goyA:
2.2		 5syfB-2goyA:
18.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X5Q_E_D16E402_1
(THYMIDYLATE SYNTHASE)		 2goy ADENOSINE
PHOSPHOSULFATE
REDUCTASE
(Pseudomonas
aeruginosa) 		4 / 6 PHE A 193
ILE A  45
LEU A  69
GLY A 161
 None
 0.95A 5x5qE-2goyA:
undetectable		 5x5qE-2goyA:
23.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X66_F_MTXF402_1
(THYMIDYLATE SYNTHASE)		 2goy ADENOSINE
PHOSPHOSULFATE
REDUCTASE
(Pseudomonas
aeruginosa) 		5 / 12 PHE A 193
ILE A  45
LEU A  69
GLY A 161
MET A  72
 None
 1.15A 5x66F-2goyA:
undetectable		 5x66F-2goyA:
23.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B0I_B_TA1B502_1
(TUBULIN BETA CHAIN)		 2goy ADENOSINE
PHOSPHOSULFATE
REDUCTASE
(Pseudomonas
aeruginosa) 		5 / 12 ASP A  44
LEU A 213
ALA A  73
PRO A 195
LEU A 196
 None
 1.10A 6b0iB-2goyA:
2.2		 6b0iB-2goyA:
14.69