SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2gpj'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NT2_A_SAMA301_0
(FIBRILLARIN-LIKE
PRE-RRNA PROCESSING
PROTEIN)		 2gpj SIDEROPHORE-INTERACT
ING PROTEIN
(Shewanella
putrefaciens) 		6 / 12 GLY A 118
ALA A 196
SER A 223
ALA A 141
ASP A 119
ILE A 143
 None
None
None
None
ACY  A 509 (-3.7A)
None
 1.29A 1nt2A-2gpjA:
6.2		 1nt2A-2gpjA:
24.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PNJ_B_CHDB502_0
(FERROCHELATASE,
MITOCHONDRIAL)		 2gpj SIDEROPHORE-INTERACT
ING PROTEIN
(Shewanella
putrefaciens) 		4 / 7 ILE A 126
PRO A 191
GLY A 139
TRP A 113
 None
None
CA  A 252 ( 4.6A)
None
 1.19A 2pnjB-2gpjA:
2.2		 2pnjB-2gpjA:
24.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WUZ_A_TPFA1460_1
(LANOSTEROL
14-ALPHA-DEMETHYLASE
, PUTATIVE)		 2gpj SIDEROPHORE-INTERACT
ING PROTEIN
(Shewanella
putrefaciens) 		5 / 10 PHE A  48
ALA A  83
ALA A  87
LEU A  27
VAL A  12
 None
FAD  A 500 (-3.3A)
None
None
None
 1.41A 2wuzA-2gpjA:
undetectable		 2wuzA-2gpjA:
19.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WUZ_B_TPFB1460_1
(LANOSTEROL
14-ALPHA-DEMETHYLASE
, PUTATIVE)		 2gpj SIDEROPHORE-INTERACT
ING PROTEIN
(Shewanella
putrefaciens) 		5 / 10 PHE A  48
ALA A  83
ALA A  87
LEU A  27
VAL A  12
 None
FAD  A 500 (-3.3A)
None
None
None
 1.39A 2wuzB-2gpjA:
undetectable		 2wuzB-2gpjA:
19.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZI9_A_CL9A401_2
(DEOXYCYTIDINE KINASE)		 2gpj SIDEROPHORE-INTERACT
ING PROTEIN
(Shewanella
putrefaciens) 		3 / 3 ASP A  73
PHE A  74
LEU A  76
 EDO  A 502 ( 3.6A)
None
None
 0.68A 2zi9A-2gpjA:
undetectable		 2zi9A-2gpjA:
21.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EM0_B_CHDB152_0
(ILEAL BILE
ACID-BINDING PROTEIN)		 2gpj SIDEROPHORE-INTERACT
ING PROTEIN
(Shewanella
putrefaciens) 		4 / 8 ILE A 107
ASN A 135
VAL A 160
GLY A 139
 None
None
None
CA  A 252 ( 4.6A)
 0.83A 3em0B-2gpjA:
undetectable		 3em0B-2gpjA:
19.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WIP_G_ACHG301_0
(ACETYLCHOLINE-BINDIN
G PROTEIN)		 2gpj SIDEROPHORE-INTERACT
ING PROTEIN
(Shewanella
putrefaciens) 		4 / 8 THR A 222
TYR A 225
ARG A 206
LEU A 205
 None
FAD  A 500 (-3.6A)
CL  A 254 (-4.4A)
None
 1.28A 3wipG-2gpjA:
undetectable
3wipH-2gpjA:
undetectable		 3wipG-2gpjA:
21.40
3wipH-2gpjA:
21.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WIP_J_ACHJ301_0
(ACETYLCHOLINE-BINDIN
G PROTEIN)		 2gpj SIDEROPHORE-INTERACT
ING PROTEIN
(Shewanella
putrefaciens) 		4 / 8 ARG A 206
LEU A 205
THR A 222
TYR A 225
 CL  A 254 (-4.4A)
None
None
FAD  A 500 (-3.6A)
 1.28A 3wipF-2gpjA:
undetectable
3wipJ-2gpjA:
undetectable		 3wipF-2gpjA:
21.40
3wipJ-2gpjA:
21.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LRH_F_FOLF301_1
(FOLATE RECEPTOR
ALPHA)		 2gpj SIDEROPHORE-INTERACT
ING PROTEIN
(Shewanella
putrefaciens) 		3 / 3 ASP A  73
TRP A 164
SER A 127
 EDO  A 502 ( 3.6A)
None
EDO  A 502 (-3.6A)
 1.09A 4lrhF-2gpjA:
undetectable		 4lrhF-2gpjA:
18.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TUD_D_ERMD1201_2
(5-HYDROXYTRYPTAMINE
RECEPTOR 2B,SOLUBLE
CYTOCHROME B562
CHIMERA)		 2gpj SIDEROPHORE-INTERACT
ING PROTEIN
(Shewanella
putrefaciens) 		4 / 6 LEU A 130
THR A  61
LEU A 116
LEU A 205
 None
FAD  A 500 (-4.0A)
None
None
 0.97A 5tudD-2gpjA:
undetectable		 5tudD-2gpjA:
21.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HU9_H_PCFH604_0
(CYTOCHROME B-C1
COMPLEX SUBUNIT 8
CYTOCHROME C OXIDASE
POLYPEPTIDE 5A,
MITOCHONDRIAL)		 2gpj SIDEROPHORE-INTERACT
ING PROTEIN
(Shewanella
putrefaciens) 		4 / 8 GLY A  81
SER A  84
ALA A  87
LYS A  88
 FAD  A 500 (-3.4A)
FAD  A 500 (-3.2A)
None
None
 0.62A 6hu9H-2gpjA:
undetectable
6hu9e-2gpjA:
undetectable		 6hu9H-2gpjA:
15.48
6hu9e-2gpjA:
21.52