SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2gpz'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A27_A_ESTA350_1
(17-BETA-HYDROXYSTERO
ID-DEHYDROGENASE)		 2gpz TRANSTHYRETIN-LIKE
PROTEIN
(Salmonella
enterica) 		5 / 12 VAL A  25
GLY A  41
LEU A  52
VAL A 100
PHE A  67
 None
 1.33A 1a27A-2gpzA:
undetectable		 1a27A-2gpzA:
16.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T86_A_CAMA1422_0
(CYTOCHROME P450-CAM)		 2gpz TRANSTHYRETIN-LIKE
PROTEIN
(Salmonella
enterica) 		4 / 8 THR A  69
THR A 111
VAL A   9
VAL A 100
 None
 0.84A 1t86A-2gpzA:
undetectable		 1t86A-2gpzA:
16.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RXH_A_HSMA7_1
(CATIONIC TRYPSIN)		 2gpz TRANSTHYRETIN-LIKE
PROTEIN
(Salmonella
enterica) 		4 / 5 ASP A  44
SER A   8
VAL A   9
GLY A  47
 SO4  A 116 (-3.1A)
None
None
None
 1.06A 3rxhA-2gpzA:
undetectable		 3rxhA-2gpzA:
16.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6F7L_B_ACTB503_0
(AMINE OXIDASE LKCE)		 2gpz TRANSTHYRETIN-LIKE
PROTEIN
(Salmonella
enterica) 		3 / 3 VAL A  25
GLU A  24
ILE A  49
 None
 0.62A 6f7lB-2gpzA:
undetectable		 6f7lB-2gpzA:
11.03