SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2gqb'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1XZX_X_T3X500_1 (THYROID HORMONE RECEPTOR BETA-1)	2gqb	CONSERVED HYPOTHETICAL PROTEIN (Rhodopseudomonas palustris)	5 / 12	ILE A 7 ILE A 11 LEU A 73 ILE A 128 PHE A 12	None	1.25A	1xzxX-2gqbA: undetectable	1xzxX-2gqbA: 16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3S3V_A_TOPA187_1 (DIHYDROFOLATE REDUCTASE)	2gqb	CONSERVED HYPOTHETICAL PROTEIN (Rhodopseudomonas palustris)	5 / 12	ILE A 47 PHE A 12 ILE A 7 LEU A 117 VAL A 49	None	1.05A	3s3vA-2gqbA: undetectable	3s3vA-2gqbA: 19.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4AC9_C_DXCC1475_0 (MJ0495-LIKE PROTEIN)	2gqb	CONSERVED HYPOTHETICAL PROTEIN (Rhodopseudomonas palustris)	4 / 8	ILE A 7 ILE A 11 PHE A 12 GLY A 122	None	0.82A	4ac9C-2gqbA: undetectable	4ac9C-2gqbA: 16.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5UUN_B_ACTB307_0 (GLUTATHIONE S-TRANSFERASE-LIKE PROTEIN)	2gqb	CONSERVED HYPOTHETICAL PROTEIN (Rhodopseudomonas palustris)	3 / 3	LEU A 89 ALA A 85 LEU A 109	None	0.46A	5uunB-2gqbA: undetectable	5uunB-2gqbA: 19.18

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1XZX_X_T3X500_1","THYROID HORMONE RECEPTOR BETA-1","2gqb","CONSERVED HYPOTHETICAL PROTEIN","Rhodopseudomonas palustris",5,"ILE A   7;ILE A  11;LEU A  73;ILE A 128;PHE A  12","None","1.25A","1xzxX-2gqbA:undetectable","1xzxX-2gqbA:16.67"],["3S3V_A_TOPA187_1","DIHYDROFOLATE REDUCTASE","2gqb","CONSERVED HYPOTHETICAL PROTEIN","Rhodopseudomonas palustris",5,"ILE A  47;PHE A  12;ILE A   7;LEU A 117;VAL A  49","None","1.05A","3s3vA-2gqbA:undetectable","3s3vA-2gqbA:19.70"],["4AC9_C_DXCC1475_0","MJ0495-LIKE PROTEIN","2gqb","CONSERVED HYPOTHETICAL PROTEIN","Rhodopseudomonas palustris",4,"ILE A   7;ILE A  11;PHE A  12;GLY A 122","None","0.82A","4ac9C-2gqbA:undetectable","4ac9C-2gqbA:16.83"],["5UUN_B_ACTB307_0","GLUTATHIONE S-TRANSFERASE-LIKE PROTEIN","2gqb","CONSERVED HYPOTHETICAL PROTEIN","Rhodopseudomonas palustris",3,"LEU A  89;ALA A  85;LEU A 109","None","0.46A","5uunB-2gqbA:undetectable","5uunB-2gqbA:19.18"]]