SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2gqd'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JIN_A_KTNA801_1
(CYTOCHROME P450
107A1)		 2gqd 3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
SYNTHASE 2
(Staphylococcus
aureus) 		5 / 11 ALA A 351
ALA A  82
ALA A  83
THR A 169
LEU A 239
 None
 0.98A 1jinA-2gqdA:
undetectable		 1jinA-2gqdA:
20.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NV8_B_SAMB301_0
(HEMK PROTEIN)		 2gqd 3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
SYNTHASE 2
(Staphylococcus
aureus) 		5 / 12 ILE A 352
GLY A 237
GLY A 191
ILE A 172
ALA A  79
 None
 1.03A 1nv8B-2gqdA:
undetectable		 1nv8B-2gqdA:
21.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SBR_A_VIBA501_1
(YKOF)		 2gqd 3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
SYNTHASE 2
(Staphylococcus
aureus) 		4 / 8 PHE A  75
ILE A 188
ILE A 106
THR A  76
 None
 0.82A 1sbrA-2gqdA:
undetectable		 1sbrA-2gqdA:
19.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SBR_B_VIBB503_1
(YKOF)		 2gqd 3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
SYNTHASE 2
(Staphylococcus
aureus) 		4 / 7 PHE A  75
ILE A 188
ILE A 106
THR A  76
 None
 0.80A 1sbrB-2gqdA:
undetectable		 1sbrB-2gqdA:
19.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SGU_B_MK1B2632_1
(POL POLYPROTEIN)		 2gqd 3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
SYNTHASE 2
(Staphylococcus
aureus) 		5 / 8 ILE A 106
GLY A 190
GLY A 237
ILE A 349
ALA A 194
 None
 1.30A 1sguA-2gqdA:
undetectable		 1sguA-2gqdA:
14.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UPF_B_URFB999_1
(URACIL
PHOSPHORIBOSYLTRANSF
ERASE)		 2gqd 3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
SYNTHASE 2
(Staphylococcus
aureus) 		4 / 7 MET A 232
ALA A  52
ILE A 196
PHE A 204
 None
 0.92A 1upfB-2gqdA:
undetectable		 1upfB-2gqdA:
18.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IGT_C_SAMC1003_0
(SAM DEPENDENT
METHYLTRANSFERASE)		 2gqd 3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
SYNTHASE 2
(Staphylococcus
aureus) 		5 / 12 ALA A 283
SER A 281
ALA A 318
ALA A 405
TYR A 300
 None
 1.19A 2igtC-2gqdA:
undetectable		 2igtC-2gqdA:
22.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OXT_D_SAMD300_0
(NUCLEOSIDE-2'-O-METH
YLTRANSFERASE)		 2gqd 3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
SYNTHASE 2
(Staphylococcus
aureus) 		6 / 12 GLY A 344
GLY A 109
GLY A 111
THR A 167
HIS A 403
HIS A 304
 None
 1.35A 2oxtD-2gqdA:
undetectable		 2oxtD-2gqdA:
21.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QMM_A_SAMA301_0
(UPF0217 PROTEIN
AF_1056)		 2gqd 3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
SYNTHASE 2
(Staphylococcus
aureus) 		5 / 9 LEU A 342
ILE A 349
GLY A 348
GLY A 190
LEU A  15
 None
 0.88A 2qmmA-2gqdA:
undetectable		 2qmmA-2gqdA:
19.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QMM_B_SAMB301_0
(UPF0217 PROTEIN
AF_1056)		 2gqd 3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
SYNTHASE 2
(Staphylococcus
aureus) 		5 / 11 LEU A 342
ILE A 349
GLY A 348
GLY A 190
LEU A  15
 None
 0.87A 2qmmA-2gqdA:
undetectable
2qmmB-2gqdA:
undetectable		 2qmmA-2gqdA:
19.53
2qmmB-2gqdA:
19.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X45_B_HSMB1162_1
(ALLERGEN ARG R 1)		 2gqd 3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
SYNTHASE 2
(Staphylococcus
aureus) 		3 / 3 GLU A 114
HIS A 198
GLU A 117
 None
 0.82A 2x45B-2gqdA:
undetectable		 2x45B-2gqdA:
15.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X45_C_HSMC1162_1
(ALLERGEN ARG R 1)		 2gqd 3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
SYNTHASE 2
(Staphylococcus
aureus) 		3 / 3 GLU A 114
HIS A 198
GLU A 117
 None
 0.79A 2x45C-2gqdA:
undetectable		 2x45C-2gqdA:
15.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y05_A_RALA802_1
(PROSTAGLANDIN
REDUCTASE 1)		 2gqd 3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
SYNTHASE 2
(Staphylococcus
aureus) 		4 / 7 VAL A 148
GLY A  13
VAL A  87
ASP A  21
 None
 0.94A 2y05A-2gqdA:
undetectable
2y05B-2gqdA:
undetectable		 2y05A-2gqdA:
21.78
2y05B-2gqdA:
21.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DVAC10_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		 2gqd 3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
SYNTHASE 2
(Staphylococcus
aureus) 		3 / 3 GLY A 190
GLY A 347
GLY A 168
 None
 0.43A 3bogC-2gqdA:
undetectable		 3bogC-2gqdA:
11.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_D_DVAD47_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		 2gqd 3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
SYNTHASE 2
(Staphylococcus
aureus) 		4 / 4 GLY A 344
GLY A 191
GLY A 107
GLY A 168
 None
 0.66A 3bogD-2gqdA:
undetectable		 3bogD-2gqdA:
11.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ELW_A_SAMA4633_0
(METHYLTRANSFERASE)		 2gqd 3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
SYNTHASE 2
(Staphylococcus
aureus) 		6 / 12 GLY A 109
GLY A 348
GLY A 168
GLY A 107
PHE A 353
ILE A 349
 None
 1.39A 3elwA-2gqdA:
undetectable		 3elwA-2gqdA:
22.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G88_A_SAMA303_0
(RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE G)		 2gqd 3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
SYNTHASE 2
(Staphylococcus
aureus) 		5 / 11 GLY A 190
GLY A 168
ALA A 236
ALA A  83
ALA A 160
 None
 0.94A 3g88A-2gqdA:
undetectable		 3g88A-2gqdA:
22.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G88_B_SAMB303_0
(RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE G)		 2gqd 3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
SYNTHASE 2
(Staphylococcus
aureus) 		5 / 11 GLY A 190
GLY A 168
ALA A 236
ALA A  83
ALA A 160
 None
 0.94A 3g88B-2gqdA:
undetectable		 3g88B-2gqdA:
22.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G89_A_SAMA303_0
(RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE G)		 2gqd 3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
SYNTHASE 2
(Staphylococcus
aureus) 		5 / 12 GLY A 190
GLY A 168
ALA A 236
ALA A  83
ALA A 160
 None
 0.97A 3g89A-2gqdA:
undetectable		 3g89A-2gqdA:
22.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G89_A_SAMA303_0
(RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE G)		 2gqd 3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
SYNTHASE 2
(Staphylococcus
aureus) 		5 / 12 GLY A 191
GLY A 168
ALA A 160
THR A 161
ALA A 144
 None
 1.08A 3g89A-2gqdA:
undetectable		 3g89A-2gqdA:
22.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G89_B_SAMB303_0
(RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE G)		 2gqd 3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
SYNTHASE 2
(Staphylococcus
aureus) 		5 / 11 GLY A 190
GLY A 168
ALA A 236
ALA A  83
ALA A 160
 None
 0.97A 3g89B-2gqdA:
undetectable		 3g89B-2gqdA:
22.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G89_B_SAMB303_0
(RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE G)		 2gqd 3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
SYNTHASE 2
(Staphylococcus
aureus) 		5 / 11 GLY A 191
GLY A 168
ALA A 160
THR A 161
ALA A 144
 None
 1.09A 3g89B-2gqdA:
undetectable		 3g89B-2gqdA:
22.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G8B_A_SAMA303_0
(RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE G)		 2gqd 3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
SYNTHASE 2
(Staphylococcus
aureus) 		5 / 12 GLY A 190
GLY A 168
ALA A 236
ALA A  83
ALA A 160
 None
 1.01A 3g8bA-2gqdA:
undetectable		 3g8bA-2gqdA:
22.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G8B_A_SAMA303_0
(RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE G)		 2gqd 3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
SYNTHASE 2
(Staphylococcus
aureus) 		5 / 12 GLY A 191
GLY A 168
ALA A 160
THR A 161
ALA A 144
 None
 1.06A 3g8bA-2gqdA:
undetectable		 3g8bA-2gqdA:
22.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G8B_B_SAMB303_0
(RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE G)		 2gqd 3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
SYNTHASE 2
(Staphylococcus
aureus) 		5 / 12 GLY A 190
GLY A 168
ALA A 236
ALA A  83
ALA A 160
 None
 0.95A 3g8bB-2gqdA:
undetectable		 3g8bB-2gqdA:
22.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IK6_H_HCZH800_1
(GLUTAMATE RECEPTOR 2)		 2gqd 3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
SYNTHASE 2
(Staphylococcus
aureus) 		4 / 4 LYS A 331
SER A 334
LEU A 388
SER A 357
 None
 1.36A 3ik6H-2gqdA:
0.5		 3ik6H-2gqdA:
22.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ILU_H_HFZH800_1
(GLUTAMATE RECEPTOR 2)		 2gqd 3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
SYNTHASE 2
(Staphylococcus
aureus) 		4 / 5 LYS A 331
SER A 334
LEU A 388
SER A 357
 None
 1.38A 3iluH-2gqdA:
undetectable		 3iluH-2gqdA:
22.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MDT_B_VORB506_1
(CHOLESTEROL
24-HYDROXYLASE)		 2gqd 3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
SYNTHASE 2
(Staphylococcus
aureus) 		5 / 11 LEU A  55
PHE A  58
THR A  76
ALA A 236
THR A 192
 None
 1.08A 3mdtB-2gqdA:
undetectable		 3mdtB-2gqdA:
22.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NXU_A_RITA600_1
(CYTOCHROME P450 3A4)		 2gqd 3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
SYNTHASE 2
(Staphylococcus
aureus) 		5 / 12 LEU A  15
ILE A  80
ALA A  83
ALA A 160
GLY A 344
 None
 1.02A 3nxuA-2gqdA:
undetectable		 3nxuA-2gqdA:
22.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U6T_A_KANA4699_1
(RIBOSOME
INACTIVATING PROTEIN)		 2gqd 3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
SYNTHASE 2
(Staphylococcus
aureus) 		5 / 10 ILE A 201
GLU A 117
ILE A  39
ALA A  52
GLU A  54
 None
 1.25A 3u6tA-2gqdA:
undetectable		 3u6tA-2gqdA:
19.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DAJ_A_0HKA2000_1
(MUSCARINIC
ACETYLCHOLINE
RECEPTOR M3,
LYSOZYME)		 2gqd 3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
SYNTHASE 2
(Staphylococcus
aureus) 		5 / 12 TYR A 300
SER A 357
THR A 366
ALA A 385
TRP A  26
 None
 1.48A 4dajA-2gqdA:
undetectable		 4dajA-2gqdA:
21.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E1G_B_LNLB701_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 2gqd 3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
SYNTHASE 2
(Staphylococcus
aureus) 		5 / 12 TYR A 300
GLY A 347
SER A 397
GLY A 399
LEU A 398
 None
 1.09A 4e1gB-2gqdA:
undetectable		 4e1gB-2gqdA:
22.99
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4LS7_A_1X9A504_1
(3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
SYNTHASE 2)		 2gqd 3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
SYNTHASE 2
(Staphylococcus
aureus) 		10 / 12 GLY A 109
ALA A 164
CYH A 165
GLU A 193
PHE A 204
HIS A 304
THR A 306
HIS A 341
LEU A 343
GLY A 399
 None
 0.54A 4ls7A-2gqdA:
74.0		 4ls7A-2gqdA:
66.13
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4LS7_A_1X9A504_1
(3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
SYNTHASE 2)		 2gqd 3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
SYNTHASE 2
(Staphylococcus
aureus) 		7 / 12 GLY A 109
ALA A 164
GLU A 193
PHE A 204
LEU A 343
GLY A 399
PHE A 400
 None
 0.71A 4ls7A-2gqdA:
74.0		 4ls7A-2gqdA:
66.13
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4LS7_B_1X9B503_1
(3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
SYNTHASE 2)		 2gqd 3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
SYNTHASE 2
(Staphylococcus
aureus) 		8 / 12 ALA A 164
CYH A 165
PHE A 204
HIS A 304
THR A 306
HIS A 341
LEU A 343
GLY A 399
 None
 0.59A 4ls7A-2gqdA:
74.0
4ls7B-2gqdA:
73.8		 4ls7A-2gqdA:
66.13
4ls7B-2gqdA:
66.13
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4LS7_B_1X9B503_1
(3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
SYNTHASE 2)		 2gqd 3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
SYNTHASE 2
(Staphylococcus
aureus) 		5 / 12 ALA A 164
PHE A 204
LEU A 343
GLY A 399
PHE A 400
 None
 0.79A 4ls7A-2gqdA:
74.0
4ls7B-2gqdA:
73.8		 4ls7A-2gqdA:
66.13
4ls7B-2gqdA:
66.13
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4LS7_B_1X9B503_1
(3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
SYNTHASE 2)		 2gqd 3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
SYNTHASE 2
(Staphylococcus
aureus) 		5 / 12 ILE A 110
ALA A 164
CYH A 165
HIS A 304
GLY A 399
 None
 0.83A 4ls7A-2gqdA:
74.0
4ls7B-2gqdA:
73.8		 4ls7A-2gqdA:
66.13
4ls7B-2gqdA:
66.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NKX_B_STRB601_1
(STEROID
17-ALPHA-HYDROXYLASE
/17,20 LYASE)		 2gqd 3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
SYNTHASE 2
(Staphylococcus
aureus) 		6 / 12 ALA A 345
ILE A 188
GLY A  13
ALA A  82
ALA A 144
VAL A 148
 None
 1.40A 4nkxB-2gqdA:
undetectable		 4nkxB-2gqdA:
21.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OKB_A_198A1002_2
(ANDROGEN RECEPTOR)		 2gqd 3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
SYNTHASE 2
(Staphylococcus
aureus) 		4 / 6 LEU A 378
MET A 284
LEU A 301
VAL A 363
 None
 1.20A 4okbA-2gqdA:
undetectable		 4okbA-2gqdA:
18.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OR0_A_NPSA602_1
(SERUM ALBUMIN)		 2gqd 3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
SYNTHASE 2
(Staphylococcus
aureus) 		5 / 9 PHE A 409
ALA A 291
SER A 395
LEU A 407
VAL A 406
 None
 1.17A 4or0A-2gqdA:
undetectable		 4or0A-2gqdA:
21.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PAE_A_NIZA804_1
(CATALASE-PEROXIDASE)		 2gqd 3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
SYNTHASE 2
(Staphylococcus
aureus) 		4 / 6 ASP A 214
LEU A  51
HIS A  50
THR A  44
 None
 1.34A 4paeA-2gqdA:
undetectable		 4paeA-2gqdA:
20.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R20_A_AERA602_1
(CYTOCHROME P450
FAMILY 17
POLYPEPTIDE 2)		 2gqd 3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
SYNTHASE 2
(Staphylococcus
aureus) 		4 / 8 ALA A  79
ILE A 140
GLY A 111
SER A 171
 None
 0.85A 4r20A-2gqdA:
undetectable		 4r20A-2gqdA:
21.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RVG_A_SAMA503_0
(D-MYCAROSE
3-C-METHYLTRANSFERAS
E)		 2gqd 3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
SYNTHASE 2
(Staphylococcus
aureus) 		5 / 12 THR A 145
ILE A 172
GLY A 190
ALA A 236
ILE A   9
 None
 1.05A 4rvgA-2gqdA:
undetectable		 4rvgA-2gqdA:
21.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RZV_B_032B801_2
(SERINE/THREONINE-PRO
TEIN KINASE B-RAF)		 2gqd 3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
SYNTHASE 2
(Staphylococcus
aureus) 		4 / 5 ILE A  36
PHE A  58
SER A 337
HIS A 368
 None
 1.32A 4rzvB-2gqdA:
undetectable		 4rzvB-2gqdA:
19.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZDY_A_1YNA602_1
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 2gqd 3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
SYNTHASE 2
(Staphylococcus
aureus) 		5 / 12 GLY A 190
ILE A 319
GLY A 280
THR A 264
PHE A 409
 None
 1.17A 4zdyA-2gqdA:
undetectable		 4zdyA-2gqdA:
19.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZJO_D_ERYD1101_0
(MULTIDRUG EFFLUX
PUMP SUBUNIT ACRB)		 2gqd 3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
SYNTHASE 2
(Staphylococcus
aureus) 		5 / 11 SER A 397
ALA A 287
GLU A 350
THR A 189
GLY A 190
 None
 1.43A 4zjoD-2gqdA:
undetectable		 4zjoD-2gqdA:
17.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZJO_D_ERYD1101_0
(MULTIDRUG EFFLUX
PUMP SUBUNIT ACRB)		 2gqd 3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
SYNTHASE 2
(Staphylococcus
aureus) 		5 / 11 THR A 163
SER A 397
ALA A 287
GLU A 350
GLY A 190
 None
 1.04A 4zjoD-2gqdA:
undetectable		 4zjoD-2gqdA:
17.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BW4_B_SAMB301_0
(16S RRNA
(ADENINE(1408)-N(1))
-METHYLTRANSFERASE)		 2gqd 3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
SYNTHASE 2
(Staphylococcus
aureus) 		5 / 12 GLY A 190
GLY A 348
ALA A 236
ALA A  83
ILE A 188
 None
 1.27A 5bw4B-2gqdA:
undetectable		 5bw4B-2gqdA:
24.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5C0O_H_SAMH301_1
(TRNA
(ADENINE(58)-N(1))-M
ETHYLTRANSFERASE
TRMI)		 2gqd 3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
SYNTHASE 2
(Staphylococcus
aureus) 		4 / 5 THR A 264
GLY A 279
GLU A 315
HIS A 304
 None
 1.13A 5c0oH-2gqdA:
undetectable		 5c0oH-2gqdA:
20.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ESL_A_1YNA701_1
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 2gqd 3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
SYNTHASE 2
(Staphylococcus
aureus) 		5 / 12 GLY A 190
ILE A 319
GLY A 280
THR A 264
PHE A 409
 None
 1.16A 5eslA-2gqdA:
undetectable		 5eslA-2gqdA:
19.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HIE_D_P06D801_2
(SERINE/THREONINE-PRO
TEIN KINASE B-RAF)		 2gqd 3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
SYNTHASE 2
(Staphylococcus
aureus) 		4 / 8 ILE A 349
GLY A 348
PHE A 400
ASN A 302
 None
 0.83A 5hieD-2gqdA:
undetectable		 5hieD-2gqdA:
20.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MLM_A_STRA401_1
(-)		 2gqd 3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
SYNTHASE 2
(Staphylococcus
aureus) 		5 / 12 ILE A 258
ALA A 186
SER A 246
VAL A 179
ILE A 241
 None
 1.39A 5mlmA-2gqdA:
undetectable		 5mlmA-2gqdA:
22.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0R_A_SAMA501_1
(PEPTIDE
N-METHYLTRANSFERASE)		 2gqd 3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
SYNTHASE 2
(Staphylococcus
aureus) 		4 / 4 SER A 246
ALA A 247
GLN A  91
THR A  10
 None
 1.07A 5n0rA-2gqdA:
undetectable		 5n0rA-2gqdA:
23.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0S_A_SAMA501_1
(PEPTIDE
N-METHYLTRANSFERASE)		 2gqd 3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
SYNTHASE 2
(Staphylococcus
aureus) 		4 / 4 SER A 246
ALA A 247
GLN A  91
THR A  10
 None
 1.09A 5n0sA-2gqdA:
undetectable		 5n0sA-2gqdA:
24.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0T_A_SAMA501_1
(PEPTIDE
N-METHYLTRANSFERASE)		 2gqd 3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
SYNTHASE 2
(Staphylococcus
aureus) 		4 / 5 SER A 246
ALA A 247
GLN A  91
THR A  10
 None
 1.09A 5n0tA-2gqdA:
undetectable		 5n0tA-2gqdA:
23.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0W_A_SAMA501_1
(PEPTIDE
N-METHYLTRANSFERASE)		 2gqd 3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
SYNTHASE 2
(Staphylococcus
aureus) 		4 / 4 SER A 246
ALA A 247
GLN A  91
THR A  10
 None
 1.07A 5n0wA-2gqdA:
undetectable		 5n0wA-2gqdA:
24.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0W_B_SAMB501_1
(PEPTIDE
N-METHYLTRANSFERASE)		 2gqd 3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
SYNTHASE 2
(Staphylococcus
aureus) 		4 / 5 SER A 246
ALA A 247
GLN A  91
THR A  10
 None
 1.06A 5n0wB-2gqdA:
undetectable		 5n0wB-2gqdA:
24.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0X_A_SAMA501_1
(PEPTIDE
N-METHYLTRANSFERASE)		 2gqd 3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
SYNTHASE 2
(Staphylococcus
aureus) 		4 / 4 SER A 246
ALA A 247
GLN A  91
THR A  10
 None
 1.06A 5n0xA-2gqdA:
undetectable		 5n0xA-2gqdA:
23.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N4I_A_SAMA501_1
(PEPTIDE
N-METHYLTRANSFERASE)		 2gqd 3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
SYNTHASE 2
(Staphylococcus
aureus) 		4 / 5 SER A 246
ALA A 247
GLN A  91
THR A  10
 None
 1.06A 5n4iA-2gqdA:
undetectable		 5n4iA-2gqdA:
23.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TWJ_A_SAMA201_0
(RIBOSOMAL RNA LARGE
SUBUNIT
METHYLTRANSFERASE H)		 2gqd 3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
SYNTHASE 2
(Staphylococcus
aureus) 		5 / 12 LEU A 342
ILE A 349
GLY A 348
GLY A 190
LEU A  15
 None
 0.94A 5twjA-2gqdA:
undetectable		 5twjA-2gqdA:
16.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TWJ_B_SAMB201_0
(RIBOSOMAL RNA LARGE
SUBUNIT
METHYLTRANSFERASE H)		 2gqd 3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
SYNTHASE 2
(Staphylococcus
aureus) 		5 / 10 LEU A 342
ILE A 349
GLY A 348
GLY A 190
LEU A  15
 None
 0.96A 5twjB-2gqdA:
undetectable		 5twjB-2gqdA:
16.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VKQ_A_PCFA1803_0
(NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L)		 2gqd 3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
SYNTHASE 2
(Staphylococcus
aureus) 		5 / 10 TYR A 255
LYS A 359
ILE A 358
ILE A 390
LEU A 388
 None
 1.30A 5vkqA-2gqdA:
undetectable
5vkqD-2gqdA:
undetectable		 5vkqA-2gqdA:
14.49
5vkqD-2gqdA:
14.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VKQ_B_PCFB1808_0
(NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L)		 2gqd 3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
SYNTHASE 2
(Staphylococcus
aureus) 		5 / 10 TYR A 255
LYS A 359
ILE A 358
ILE A 390
LEU A 388
 None
 1.30A 5vkqA-2gqdA:
undetectable
5vkqB-2gqdA:
undetectable		 5vkqA-2gqdA:
14.49
5vkqB-2gqdA:
14.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VKQ_D_PCFD1801_0
(NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L)		 2gqd 3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
SYNTHASE 2
(Staphylococcus
aureus) 		5 / 10 TYR A 255
LYS A 359
ILE A 358
ILE A 390
LEU A 388
 None
 1.30A 5vkqC-2gqdA:
undetectable
5vkqD-2gqdA:
undetectable		 5vkqC-2gqdA:
14.49
5vkqD-2gqdA:
14.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VW4_A_NCAA403_0
(FERREDOXIN--NADP
REDUCTASE)		 2gqd 3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
SYNTHASE 2
(Staphylococcus
aureus) 		5 / 9 SER A 397
GLY A 168
ALA A 166
GLY A 348
GLU A 350
 None
 0.98A 5vw4A-2gqdA:
undetectable		 5vw4A-2gqdA:
21.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6F7L_B_ACTB503_0
(AMINE OXIDASE LKCE)		 2gqd 3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
SYNTHASE 2
(Staphylococcus
aureus) 		3 / 3 VAL A   7
GLU A 257
ILE A 241
 None
 0.63A 6f7lB-2gqdA:
undetectable		 6f7lB-2gqdA:
22.95