SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2gqf'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E7C_A_HLTA4007_1
(SERUM ALBUMIN)		 2gqf HYPOTHETICAL PROTEIN
HI0933
(Haemophilus
influenzae) 		4 / 8 TYR A 229
LEU A 261
ASN A 264
LEU A 216
 None
 0.64A 1e7cA-2gqfA:
undetectable		 1e7cA-2gqfA:
20.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1W76_A_GNTA1538_1
(ACETYLCHOLINESTERASE)		 2gqf HYPOTHETICAL PROTEIN
HI0933
(Haemophilus
influenzae) 		5 / 11 ASP A 105
GLY A  49
GLY A  48
SER A  46
PHE A  53
 None
None
None
FAD  A 403 (-4.5A)
None
 1.39A 1w76A-2gqfA:
undetectable		 1w76A-2gqfA:
22.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NNH_A_9CRA502_1
(CYTOCHROME P450 2C8)		 2gqf HYPOTHETICAL PROTEIN
HI0933
(Haemophilus
influenzae) 		5 / 12 ILE A  10
ILE A 181
LEU A 160
ASN A 159
VAL A 363
 FAD  A 403 (-4.9A)
None
None
None
None
 0.89A 2nnhA-2gqfA:
undetectable		 2nnhA-2gqfA:
22.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NNH_B_9CRB502_1
(CYTOCHROME P450 2C8)		 2gqf HYPOTHETICAL PROTEIN
HI0933
(Haemophilus
influenzae) 		5 / 10 ILE A  10
ILE A 181
LEU A 160
ASN A 159
VAL A 363
 FAD  A 403 (-4.9A)
None
None
None
None
 0.96A 2nnhB-2gqfA:
undetectable		 2nnhB-2gqfA:
22.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YY8_B_SAMB500_0
(UPF0106 PROTEIN
PH0461)		 2gqf HYPOTHETICAL PROTEIN
HI0933
(Haemophilus
influenzae) 		5 / 11 LEU A 321
VAL A 318
ILE A 325
HIS A 326
GLU A 268
 None
 0.87A 2yy8A-2gqfA:
2.9
2yy8B-2gqfA:
2.8		 2yy8A-2gqfA:
20.24
2yy8B-2gqfA:
20.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3APW_B_DP0B190_1
(ALPHA-1-ACID
GLYCOPROTEIN 2)		 2gqf HYPOTHETICAL PROTEIN
HI0933
(Haemophilus
influenzae) 		5 / 12 VAL A  87
ILE A  92
GLN A 110
ALA A  14
PHE A 384
 None
None
None
FAD  A 403 (-3.7A)
FAD  A 403 (-3.7A)
 1.29A 3apwB-2gqfA:
undetectable		 3apwB-2gqfA:
17.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3APW_B_DP0B190_1
(ALPHA-1-ACID
GLYCOPROTEIN 2)		 2gqf HYPOTHETICAL PROTEIN
HI0933
(Haemophilus
influenzae) 		5 / 12 VAL A  87
ILE A  92
LEU A  44
GLN A 110
PHE A 384
 None
None
None
None
FAD  A 403 (-3.7A)
 1.38A 3apwB-2gqfA:
undetectable		 3apwB-2gqfA:
17.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3C6G_B_VD3B700_1
(CYTOCHROME P450 2R1)		 2gqf HYPOTHETICAL PROTEIN
HI0933
(Haemophilus
influenzae) 		5 / 12 PHE A  18
ALA A  74
ALA A 395
THR A  54
VAL A  58
 None
 1.13A 3c6gB-2gqfA:
undetectable		 3c6gB-2gqfA:
20.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DZY_D_BRLD478_2
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 2gqf HYPOTHETICAL PROTEIN
HI0933
(Haemophilus
influenzae) 		4 / 4 ILE A 220
GLN A 246
ILE A 239
LEU A  99
 None
 1.23A 3dzyD-2gqfA:
undetectable		 3dzyD-2gqfA:
18.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VYW_B_SAMB401_0
(MNMC2)		 2gqf HYPOTHETICAL PROTEIN
HI0933
(Haemophilus
influenzae) 		5 / 12 GLY A  13
GLY A  40
LEU A  44
ALA A 163
PHE A 384
 FAD  A 403 (-3.1A)
None
None
FAD  A 403 (-4.6A)
FAD  A 403 (-3.7A)
 1.26A 3vywB-2gqfA:
undetectable		 3vywB-2gqfA:
23.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WZE_A_BAXA1201_2
(VASCULAR ENDOTHELIAL
GROWTH FACTOR
RECEPTOR 2)		 2gqf HYPOTHETICAL PROTEIN
HI0933
(Haemophilus
influenzae) 		5 / 8 VAL A 189
VAL A 348
LEU A 373
ILE A 190
PHE A  70
 None
 1.50A 3wzeA-2gqfA:
undetectable		 3wzeA-2gqfA:
22.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JQ1_B_NPSB401_1
(ALDO-KETO REDUCTASE
FAMILY 1 MEMBER C2)		 2gqf HYPOTHETICAL PROTEIN
HI0933
(Haemophilus
influenzae) 		4 / 8 TYR A 201
VAL A 244
ILE A 220
LEU A 261
 None
 0.92A 4jq1B-2gqfA:
undetectable		 4jq1B-2gqfA:
23.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QTU_B_SAMB301_0
(PUTATIVE
METHYLTRANSFERASE
BUD23)		 2gqf HYPOTHETICAL PROTEIN
HI0933
(Haemophilus
influenzae) 		5 / 12 GLY A  16
GLY A  11
ILE A  39
ILE A 161
ALA A  20
 None
FAD  A 403 (-3.1A)
None
None
None
 1.10A 4qtuB-2gqfA:
undetectable		 4qtuB-2gqfA:
20.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QTU_D_SAMD301_0
(PUTATIVE
METHYLTRANSFERASE
BUD23)		 2gqf HYPOTHETICAL PROTEIN
HI0933
(Haemophilus
influenzae) 		5 / 12 GLY A  16
GLY A  11
ILE A  39
ILE A 161
ALA A  20
 None
FAD  A 403 (-3.1A)
None
None
None
 1.11A 4qtuD-2gqfA:
undetectable		 4qtuD-2gqfA:
20.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V20_A_ACTA1444_0
(CELLOBIOHYDROLASE)		 2gqf HYPOTHETICAL PROTEIN
HI0933
(Haemophilus
influenzae) 		4 / 5 GLY A 166
THR A 344
GLY A 347
GLU A 371
 None
None
None
FAD  A 403 (-4.1A)
 1.08A 4v20A-2gqfA:
undetectable		 4v20A-2gqfA:
20.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XOY_A_DX4A401_0
(MITOGEN-ACTIVATED
PROTEIN KINASE 1)		 2gqf HYPOTHETICAL PROTEIN
HI0933
(Haemophilus
influenzae) 		4 / 6 ALA A  21
LYS A  25
GLN A  22
LEU A  86
 None
 0.90A 4xoyA-2gqfA:
undetectable		 4xoyA-2gqfA:
23.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XP3_A_DX4A401_0
(MITOGEN-ACTIVATED
PROTEIN KINASE 1)		 2gqf HYPOTHETICAL PROTEIN
HI0933
(Haemophilus
influenzae) 		4 / 6 ALA A  21
LYS A  25
GLN A  22
LEU A  86
 None
 0.92A 4xp3A-2gqfA:
undetectable		 4xp3A-2gqfA:
23.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5D4U_C_SAMC301_0
(UNCHARACTERIZED
PROTEIN MJ0489)		 2gqf HYPOTHETICAL PROTEIN
HI0933
(Haemophilus
influenzae) 		5 / 12 ILE A 161
MET A 358
LEU A 160
GLY A  11
ILE A  10
 None
None
None
FAD  A 403 (-3.1A)
FAD  A 403 (-4.9A)
 1.03A 5d4uC-2gqfA:
undetectable		 5d4uC-2gqfA:
20.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HES_B_032B401_2
(MITOGEN-ACTIVATED
PROTEIN KINASE
KINASE KINASE MLT)		 2gqf HYPOTHETICAL PROTEIN
HI0933
(Haemophilus
influenzae) 		4 / 4 CYH A  51
PHE A 103
ILE A  84
GLY A 381
 None
None
None
FAD  A 403 (-3.0A)
 0.85A 5hesB-2gqfA:
undetectable		 5hesB-2gqfA:
21.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IK1_A_CAMA503_0
(CAMPHOR
5-MONOOXYGENASE)		 2gqf HYPOTHETICAL PROTEIN
HI0933
(Haemophilus
influenzae) 		4 / 7 PHE A 368
GLY A 186
ILE A 353
VAL A 352
 None
 0.82A 5ik1A-2gqfA:
undetectable		 5ik1A-2gqfA:
21.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NWU_A_ACAA18_2
(WTFP-TAG,GP41)		 2gqf HYPOTHETICAL PROTEIN
HI0933
(Haemophilus
influenzae) 		3 / 3 LEU A 262
LEU A 261
TRP A 328
 None
 0.79A 5nwuA-2gqfA:
undetectable		 5nwuA-2gqfA:
8.65