SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2gqw'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HRK_B_CHDB2502_0
(FERROCHELATASE)		 2gqw FERREDOXIN REDUCTASE
(Pseudomonas
sp.
KKS102) 		4 / 8 ARG A 208
LEU A 220
VAL A 151
GLY A 152
 None
 1.02A 1hrkB-2gqwA:
undetectable		 1hrkB-2gqwA:
20.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2P2F_B_ACTB653_0
(ACETYL-COENZYME A
SYNTHETASE)		 2gqw FERREDOXIN REDUCTASE
(Pseudomonas
sp.
KKS102) 		4 / 4 VAL A 274
THR A 275
VAL A 257
GLY A 261
 None
 1.15A 2p2fB-2gqwA:
2.8		 2p2fB-2gqwA:
20.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PO5_B_CHDB503_0
(FERROCHELATASE,
MITOCHONDRIAL)		 2gqw FERREDOXIN REDUCTASE
(Pseudomonas
sp.
KKS102) 		3 / 3 LEU A 377
PRO A 376
LEU A 380
 None
 0.56A 2po5B-2gqwA:
undetectable		 2po5B-2gqwA:
20.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PO7_B_CHDB503_0
(FERROCHELATASE,
MITOCHONDRIAL)		 2gqw FERREDOXIN REDUCTASE
(Pseudomonas
sp.
KKS102) 		3 / 3 LEU A 377
PRO A 376
LEU A 380
 None
 0.57A 2po7B-2gqwA:
undetectable		 2po7B-2gqwA:
20.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WA2_A_SAMA1248_0
(NON-STRUCTURAL
PROTEIN 5)		 2gqw FERREDOXIN REDUCTASE
(Pseudomonas
sp.
KKS102) 		5 / 12 GLY A 298
GLY A  14
GLY A  16
SER A  21
THR A  81
 None
FAD  A1449 (-3.2A)
FAD  A1449 (-3.5A)
None
FAD  A1449 ( 4.3A)
 0.83A 2wa2A-2gqwA:
2.1		 2wa2A-2gqwA:
22.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YQZ_B_SAMB401_0
(HYPOTHETICAL PROTEIN
TTHA0223)		 2gqw FERREDOXIN REDUCTASE
(Pseudomonas
sp.
KKS102) 		5 / 12 GLY A 153
ILE A 235
VAL A 151
LEU A 173
VAL A 202
 None
 0.90A 2yqzB-2gqwA:
3.4		 2yqzB-2gqwA:
23.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A2Q_A_ACAA602_1
(6-AMINOHEXANOATE-CYC
LIC-DIMER HYDROLASE)		 2gqw FERREDOXIN REDUCTASE
(Pseudomonas
sp.
KKS102) 		4 / 7 ASN A 293
ALA A 270
ALA A 108
GLN A 277
 None
 0.87A 3a2qA-2gqwA:
undetectable		 3a2qA-2gqwA:
27.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_E_SVRE510_3
(PHOSPHOLIPASE A2)		 2gqw FERREDOXIN REDUCTASE
(Pseudomonas
sp.
KKS102) 		4 / 5 VAL A 106
VAL A  12
THR A 275
THR A 104
 None
 1.13A 3bjwG-2gqwA:
undetectable		 3bjwG-2gqwA:
15.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_F_SVRF509_1
(PHOSPHOLIPASE A2)		 2gqw FERREDOXIN REDUCTASE
(Pseudomonas
sp.
KKS102) 		4 / 5 VAL A 106
VAL A  12
THR A 275
THR A 104
 None
 1.11A 3bjwC-2gqwA:
undetectable		 3bjwC-2gqwA:
15.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_H_SVRH511_2
(PHOSPHOLIPASE A2)		 2gqw FERREDOXIN REDUCTASE
(Pseudomonas
sp.
KKS102) 		4 / 5 VAL A 106
VAL A  12
THR A 275
THR A 104
 None
 1.05A 3bjwD-2gqwA:
undetectable		 3bjwD-2gqwA:
15.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EL5_B_1UNB201_2
(PROTEASE)		 2gqw FERREDOXIN REDUCTASE
(Pseudomonas
sp.
KKS102) 		5 / 12 GLY A 121
ALA A 122
VAL A 231
THR A 128
VAL A 126
 None
FMT  A2002 (-3.7A)
None
GOL  A1001 (-4.3A)
None
 0.93A 3el5B-2gqwA:
undetectable		 3el5B-2gqwA:
11.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HCR_A_CHDA4_0
(FERROCHELATASE,
MITOCHONDRIAL)		 2gqw FERREDOXIN REDUCTASE
(Pseudomonas
sp.
KKS102) 		3 / 3 LEU A 377
PRO A 376
LEU A 380
 None
 0.51A 3hcrA-2gqwA:
2.1		 3hcrA-2gqwA:
20.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4BLV_A_SAMA1281_0
(RIBOSOMAL RNA LARGE
SUBUNIT
METHYLTRANSFERASE J)		 2gqw FERREDOXIN REDUCTASE
(Pseudomonas
sp.
KKS102) 		5 / 12 GLY A  14
GLY A 110
LEU A  77
GLY A  79
PRO A  45
 FAD  A1449 (-3.2A)
FAD  A1449 (-3.3A)
None
None
None
 1.01A 4blvA-2gqwA:
2.4		 4blvA-2gqwA:
22.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KRA_C_CPFC401_1
(OUTER MEMBRANE
PROTEIN F)		 2gqw FERREDOXIN REDUCTASE
(Pseudomonas
sp.
KKS102) 		5 / 9 ARG A  48
TYR A  46
GLU A  43
GLY A  79
THR A  81
 FAD  A1449 (-4.0A)
None
None
None
FAD  A1449 ( 4.3A)
 1.10A 4kraC-2gqwA:
0.0		 4kraC-2gqwA:
21.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OLT_A_GCSA303_1
(CHITOSANASE)		 2gqw FERREDOXIN REDUCTASE
(Pseudomonas
sp.
KKS102) 		4 / 6 ILE A 255
ASP A 241
ARG A 245
GLY A 248
 None
 0.96A 4oltA-2gqwA:
undetectable		 4oltA-2gqwA:
21.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OQR_A_2UOA502_1
(CYP105AS1)		 2gqw FERREDOXIN REDUCTASE
(Pseudomonas
sp.
KKS102) 		5 / 9 VAL A 274
ILE A 299
ALA A 302
VAL A  12
ALA A 108
 None
 1.11A 4oqrA-2gqwA:
undetectable		 4oqrA-2gqwA:
25.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5E5J_A_017A201_3
(PROTEASE)		 2gqw FERREDOXIN REDUCTASE
(Pseudomonas
sp.
KKS102) 		3 / 3 ASP A 134
VAL A 232
LEU A 160
 None
 0.66A 5e5jB-2gqwA:
undetectable		 5e5jB-2gqwA:
13.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGL_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 2gqw FERREDOXIN REDUCTASE
(Pseudomonas
sp.
KKS102) 		3 / 3 VAL A 171
VAL A 202
GLN A 200
 None
 0.66A 5qglA-2gqwA:
undetectable		 5qglA-2gqwA:
19.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGN_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 2gqw FERREDOXIN REDUCTASE
(Pseudomonas
sp.
KKS102) 		3 / 3 VAL A 171
VAL A 202
GLN A 200
 None
 0.64A 5qgnA-2gqwA:
undetectable		 5qgnA-2gqwA:
19.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGV_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 2gqw FERREDOXIN REDUCTASE
(Pseudomonas
sp.
KKS102) 		3 / 3 VAL A 171
VAL A 202
GLN A 200
 None
 0.68A 5qgvA-2gqwA:
undetectable		 5qgvA-2gqwA:
19.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGW_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 2gqw FERREDOXIN REDUCTASE
(Pseudomonas
sp.
KKS102) 		3 / 3 VAL A 171
VAL A 202
GLN A 200
 None
 0.71A 5qgwA-2gqwA:
undetectable		 5qgwA-2gqwA:
19.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGX_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 2gqw FERREDOXIN REDUCTASE
(Pseudomonas
sp.
KKS102) 		3 / 3 VAL A 171
VAL A 202
GLN A 200
 None
 0.68A 5qgxA-2gqwA:
undetectable		 5qgxA-2gqwA:
19.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QH1_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 2gqw FERREDOXIN REDUCTASE
(Pseudomonas
sp.
KKS102) 		3 / 3 VAL A 171
VAL A 202
GLN A 200
 None
 0.67A 5qh1A-2gqwA:
undetectable		 5qh1A-2gqwA:
19.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QH4_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 2gqw FERREDOXIN REDUCTASE
(Pseudomonas
sp.
KKS102) 		3 / 3 VAL A 171
VAL A 202
GLN A 200
 None
 0.68A 5qh4A-2gqwA:
undetectable		 5qh4A-2gqwA:
19.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QH5_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 2gqw FERREDOXIN REDUCTASE
(Pseudomonas
sp.
KKS102) 		3 / 3 VAL A 171
VAL A 202
GLN A 200
 None
 0.64A 5qh5A-2gqwA:
undetectable		 5qh5A-2gqwA:
19.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QH7_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 2gqw FERREDOXIN REDUCTASE
(Pseudomonas
sp.
KKS102) 		3 / 3 VAL A 171
VAL A 202
GLN A 200
 None
 0.68A 5qh7A-2gqwA:
undetectable		 5qh7A-2gqwA:
19.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QH9_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 2gqw FERREDOXIN REDUCTASE
(Pseudomonas
sp.
KKS102) 		3 / 3 VAL A 171
VAL A 202
GLN A 200
 None
 0.72A 5qh9A-2gqwA:
undetectable		 5qh9A-2gqwA:
19.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QHC_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 2gqw FERREDOXIN REDUCTASE
(Pseudomonas
sp.
KKS102) 		3 / 3 VAL A 171
VAL A 202
GLN A 200
 None
 0.68A 5qhcA-2gqwA:
undetectable		 5qhcA-2gqwA:
19.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QHE_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 2gqw FERREDOXIN REDUCTASE
(Pseudomonas
sp.
KKS102) 		3 / 3 VAL A 171
VAL A 202
GLN A 200
 None
 0.72A 5qheA-2gqwA:
undetectable		 5qheA-2gqwA:
19.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QHF_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 2gqw FERREDOXIN REDUCTASE
(Pseudomonas
sp.
KKS102) 		3 / 3 VAL A 171
VAL A 202
GLN A 200
 None
 0.71A 5qhfA-2gqwA:
undetectable		 5qhfA-2gqwA:
19.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QHG_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 2gqw FERREDOXIN REDUCTASE
(Pseudomonas
sp.
KKS102) 		3 / 3 VAL A 171
VAL A 202
GLN A 200
 None
 0.64A 5qhgA-2gqwA:
undetectable		 5qhgA-2gqwA:
19.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UUN_A_ACTA312_0
(GLUTATHIONE
S-TRANSFERASE-LIKE
PROTEIN)		 2gqw FERREDOXIN REDUCTASE
(Pseudomonas
sp.
KKS102) 		3 / 3 ILE A 328
VAL A 368
PRO A 350
 None
 0.64A 5uunA-2gqwA:
undetectable		 5uunA-2gqwA:
21.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CZM_D_HISD402_0
(ATP
PHOSPHORIBOSYLTRANSF
ERASE CATALYTIC
SUBUNIT)		 2gqw FERREDOXIN REDUCTASE
(Pseudomonas
sp.
KKS102) 		5 / 8 GLY A  14
LEU A  13
VAL A 268
VAL A 274
LEU A 105
 FAD  A1449 (-3.2A)
None
None
None
None
 1.36A 6czmD-2gqwA:
undetectable
6czmF-2gqwA:
undetectable		 6czmD-2gqwA:
23.29
6czmF-2gqwA:
23.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CZM_E_HISE402_0
(ATP
PHOSPHORIBOSYLTRANSF
ERASE CATALYTIC
SUBUNIT)		 2gqw FERREDOXIN REDUCTASE
(Pseudomonas
sp.
KKS102) 		5 / 9 VAL A 268
VAL A 274
LEU A 105
GLY A  14
LEU A  13
 None
None
None
FAD  A1449 (-3.2A)
None
 1.33A 6czmD-2gqwA:
undetectable
6czmE-2gqwA:
undetectable		 6czmD-2gqwA:
23.29
6czmE-2gqwA:
23.29