SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2gs0'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V55_C_CHDC3271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE III
CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART)		 2gs0 RNA POLYMERASE II
TRANSCRIPTION FACTOR
B SUBUNIT 1
(Saccharomyces
cerevisiae) 		4 / 7 LYS A 101
LEU A 104
GLN A 105
PHE A  89
 None
 1.03A 1v55C-2gs0A:
undetectable
1v55J-2gs0A:
undetectable		 1v55C-2gs0A:
14.18
1v55J-2gs0A:
17.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIJ_C_CHDC271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)		 2gs0 RNA POLYMERASE II
TRANSCRIPTION FACTOR
B SUBUNIT 1
(Saccharomyces
cerevisiae) 		4 / 7 LYS A 101
LEU A 104
GLN A 105
PHE A  89
 None
 1.04A 2eijC-2gs0A:
undetectable
2eijJ-2gs0A:
undetectable		 2eijC-2gs0A:
14.18
2eijJ-2gs0A:
17.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIJ_P_CHDP1271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)		 2gs0 RNA POLYMERASE II
TRANSCRIPTION FACTOR
B SUBUNIT 1
(Saccharomyces
cerevisiae) 		4 / 7 LYS A 101
LEU A 104
GLN A 105
PHE A  89
 None
 1.04A 2eijP-2gs0A:
undetectable
2eijW-2gs0A:
undetectable		 2eijP-2gs0A:
14.18
2eijW-2gs0A:
17.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIM_C_CHDC271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)		 2gs0 RNA POLYMERASE II
TRANSCRIPTION FACTOR
B SUBUNIT 1
(Saccharomyces
cerevisiae) 		4 / 7 LYS A 101
LEU A 104
GLN A 105
PHE A  89
 None
 0.98A 2eimC-2gs0A:
undetectable
2eimJ-2gs0A:
undetectable		 2eimC-2gs0A:
14.18
2eimJ-2gs0A:
17.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WEY_B_EV1B1771_1
(CAMP AND
CAMP-INHIBITED CGMP
3', 5'-CYCLIC
PHOSPHODIESTERASE)		 2gs0 RNA POLYMERASE II
TRANSCRIPTION FACTOR
B SUBUNIT 1
(Saccharomyces
cerevisiae) 		4 / 8 LEU A  48
VAL A  40
ILE A  16
PHE A  91
 None
 0.95A 2weyB-2gs0A:
undetectable		 2weyB-2gs0A:
14.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EL9_A_DR7A100_1
(PROTEASE)		 2gs0 RNA POLYMERASE II
TRANSCRIPTION FACTOR
B SUBUNIT 1
(Saccharomyces
cerevisiae) 		4 / 8 ASP A  35
GLY A  14
ILE A  15
THR A  39
 None
 0.65A 3el9A-2gs0A:
undetectable		 3el9A-2gs0A:
23.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K5V_B_STIB2_2
(TYROSINE-PROTEIN
KINASE ABL1)		 2gs0 RNA POLYMERASE II
TRANSCRIPTION FACTOR
B SUBUNIT 1
(Saccharomyces
cerevisiae) 		4 / 6 LEU A  60
VAL A  22
VAL A  40
ILE A 107
 None
 1.18A 3k5vB-2gs0A:
undetectable		 3k5vB-2gs0A:
17.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4G19_A_ACTA304_0
(GLUTATHIONE
TRANSFERASE GTE1)		 2gs0 RNA POLYMERASE II
TRANSCRIPTION FACTOR
B SUBUNIT 1
(Saccharomyces
cerevisiae) 		4 / 5 ALA A  50
ILE A 100
LEU A 104
LYS A 101
 None
 1.11A 4g19A-2gs0A:
undetectable		 4g19A-2gs0A:
16.94