SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2gs4'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TUV_A_VK3A4558_1
(PROTEIN YGIN)		 2gs4 PROTEIN YCIF
(Escherichia
coli) 		4 / 7 GLU A 110
HIS A  47
LEU A  28
MET A  78
 None
 1.06A 1tuvA-2gs4A:
undetectable		 1tuvA-2gs4A:
22.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V54_C_CHDC3525_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE I
CYTOCHROME C OXIDASE
POLYPEPTIDE III)		 2gs4 PROTEIN YCIF
(Escherichia
coli) 		4 / 7 ASP A  16
THR A  17
TYR A  18
HIS A  47
 None
 1.19A 1v54A-2gs4A:
2.4
1v54C-2gs4A:
4.0		 1v54A-2gs4A:
14.17
1v54C-2gs4A:
20.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V54_P_CHDP4525_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE I
CYTOCHROME C OXIDASE
POLYPEPTIDE III)		 2gs4 PROTEIN YCIF
(Escherichia
coli) 		4 / 7 ASP A  16
THR A  17
TYR A  18
HIS A  47
 None
 1.20A 1v54N-2gs4A:
2.3
1v54P-2gs4A:
4.0		 1v54N-2gs4A:
14.17
1v54P-2gs4A:
20.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V55_C_CHDC3525_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE I
CYTOCHROME C OXIDASE
POLYPEPTIDE III)		 2gs4 PROTEIN YCIF
(Escherichia
coli) 		4 / 7 ASP A  16
THR A  17
TYR A  18
HIS A  47
 None
 1.19A 1v55A-2gs4A:
2.4
1v55C-2gs4A:
4.0		 1v55A-2gs4A:
14.17
1v55C-2gs4A:
20.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V55_P_CHDP4525_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE I
CYTOCHROME C OXIDASE
POLYPEPTIDE III)		 2gs4 PROTEIN YCIF
(Escherichia
coli) 		4 / 7 ASP A  16
THR A  17
TYR A  18
HIS A  47
 None
 1.19A 1v55C-2gs4A:
4.0
1v55N-2gs4A:
undetectable
1v55P-2gs4A:
4.0		 1v55C-2gs4A:
20.32
1v55N-2gs4A:
14.17
1v55P-2gs4A:
20.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYR_C_CHDC525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 2gs4 PROTEIN YCIF
(Escherichia
coli) 		4 / 7 ASP A  16
THR A  17
TYR A  18
HIS A  47
 None
 1.20A 2dyrA-2gs4A:
undetectable
2dyrC-2gs4A:
4.0		 2dyrA-2gs4A:
14.17
2dyrC-2gs4A:
20.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYR_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 2gs4 PROTEIN YCIF
(Escherichia
coli) 		4 / 7 ASP A  16
THR A  17
TYR A  18
HIS A  47
 None
 1.20A 2dyrN-2gs4A:
2.4
2dyrP-2gs4A:
3.9		 2dyrN-2gs4A:
14.17
2dyrP-2gs4A:
20.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYS_C_CHDC304_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 2gs4 PROTEIN YCIF
(Escherichia
coli) 		4 / 6 ASP A  16
THR A  17
TYR A  18
HIS A  47
 None
 1.22A 2dysA-2gs4A:
undetectable
2dysC-2gs4A:
4.0		 2dysA-2gs4A:
14.17
2dysC-2gs4A:
20.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYS_P_CHDP304_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 2gs4 PROTEIN YCIF
(Escherichia
coli) 		4 / 6 ASP A  16
THR A  17
TYR A  18
HIS A  47
 None
 1.17A 2dysN-2gs4A:
undetectable
2dysP-2gs4A:
3.1		 2dysN-2gs4A:
14.17
2dysP-2gs4A:
20.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIJ_C_CHDC525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 2gs4 PROTEIN YCIF
(Escherichia
coli) 		4 / 7 ASP A  16
THR A  17
TYR A  18
HIS A  47
 None
 1.19A 2eijA-2gs4A:
undetectable
2eijC-2gs4A:
4.0		 2eijA-2gs4A:
14.17
2eijC-2gs4A:
20.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIJ_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 2gs4 PROTEIN YCIF
(Escherichia
coli) 		4 / 7 ASP A  16
THR A  17
TYR A  18
HIS A  47
 None
 1.19A 2eijN-2gs4A:
undetectable
2eijP-2gs4A:
4.0		 2eijN-2gs4A:
14.17
2eijP-2gs4A:
20.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIK_C_CHDC525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 2gs4 PROTEIN YCIF
(Escherichia
coli) 		4 / 7 ASP A  16
THR A  17
TYR A  18
HIS A  47
 None
 1.21A 2eikA-2gs4A:
undetectable
2eikC-2gs4A:
4.0		 2eikA-2gs4A:
14.17
2eikC-2gs4A:
20.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIK_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 2gs4 PROTEIN YCIF
(Escherichia
coli) 		4 / 7 ASP A  16
THR A  17
TYR A  18
HIS A  47
 None
 1.19A 2eikN-2gs4A:
undetectable
2eikP-2gs4A:
4.0		 2eikN-2gs4A:
14.17
2eikP-2gs4A:
20.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIL_C_CHDC525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 2gs4 PROTEIN YCIF
(Escherichia
coli) 		4 / 7 ASP A  16
THR A  17
TYR A  18
HIS A  47
 None
 1.22A 2eilA-2gs4A:
undetectable
2eilC-2gs4A:
4.0		 2eilA-2gs4A:
14.17
2eilC-2gs4A:
20.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIL_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 2gs4 PROTEIN YCIF
(Escherichia
coli) 		4 / 7 ASP A  16
THR A  17
TYR A  18
HIS A  47
 None
 1.19A 2eilN-2gs4A:
2.4
2eilP-2gs4A:
4.0		 2eilN-2gs4A:
14.17
2eilP-2gs4A:
20.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIM_A_CHDA525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 2gs4 PROTEIN YCIF
(Escherichia
coli) 		4 / 6 ASP A  16
THR A  17
TYR A  18
HIS A  47
 None
 1.16A 2eimA-2gs4A:
2.4
2eimC-2gs4A:
4.1		 2eimA-2gs4A:
14.17
2eimC-2gs4A:
20.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIM_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 2gs4 PROTEIN YCIF
(Escherichia
coli) 		4 / 6 ASP A  16
THR A  17
TYR A  18
HIS A  47
 None
 1.18A 2eimN-2gs4A:
2.6
2eimP-2gs4A:
3.9		 2eimN-2gs4A:
14.17
2eimP-2gs4A:
20.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIN_C_CHDC525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 2gs4 PROTEIN YCIF
(Escherichia
coli) 		4 / 6 ASP A  16
THR A  17
TYR A  18
HIS A  47
 None
 1.16A 2einA-2gs4A:
3.9
2einC-2gs4A:
4.0		 2einA-2gs4A:
14.17
2einC-2gs4A:
20.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIN_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 2gs4 PROTEIN YCIF
(Escherichia
coli) 		4 / 6 ASP A  16
THR A  17
TYR A  18
HIS A  47
 None
 1.17A 2einN-2gs4A:
3.8
2einP-2gs4A:
4.0		 2einN-2gs4A:
14.17
2einP-2gs4A:
20.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y69_A_CHDA1517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 2gs4 PROTEIN YCIF
(Escherichia
coli) 		4 / 7 ASP A  16
THR A  17
TYR A  18
HIS A  47
 None
 1.19A 2y69A-2gs4A:
2.4
2y69C-2gs4A:
4.1		 2y69A-2gs4A:
14.17
2y69C-2gs4A:
20.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZXW_C_CHDC525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 2gs4 PROTEIN YCIF
(Escherichia
coli) 		4 / 6 ASP A  16
THR A  17
TYR A  18
HIS A  47
 None
 1.19A 2zxwA-2gs4A:
2.5
2zxwC-2gs4A:
3.9		 2zxwA-2gs4A:
14.17
2zxwC-2gs4A:
20.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZXW_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 2gs4 PROTEIN YCIF
(Escherichia
coli) 		4 / 6 ASP A  16
THR A  17
TYR A  18
HIS A  47
 None
 1.15A 2zxwN-2gs4A:
3.1
2zxwP-2gs4A:
3.0		 2zxwN-2gs4A:
14.17
2zxwP-2gs4A:
20.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABK_C_CHDC525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 2gs4 PROTEIN YCIF
(Escherichia
coli) 		4 / 7 ASP A  16
THR A  17
TYR A  18
HIS A  47
 None
 1.23A 3abkA-2gs4A:
3.2
3abkC-2gs4A:
4.1		 3abkA-2gs4A:
14.17
3abkC-2gs4A:
20.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABK_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 2gs4 PROTEIN YCIF
(Escherichia
coli) 		4 / 7 ASP A  16
THR A  17
TYR A  18
HIS A  47
 None
 1.25A 3abkN-2gs4A:
3.1
3abkP-2gs4A:
4.0		 3abkN-2gs4A:
14.17
3abkP-2gs4A:
20.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABM_C_CHDC525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 2gs4 PROTEIN YCIF
(Escherichia
coli) 		4 / 8 ASP A  16
THR A  17
TYR A  18
HIS A  47
 None
 1.16A 3abmA-2gs4A:
2.3
3abmC-2gs4A:
4.0
3abmP-2gs4A:
4.0		 3abmA-2gs4A:
14.17
3abmC-2gs4A:
20.32
3abmP-2gs4A:
20.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABM_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 2gs4 PROTEIN YCIF
(Escherichia
coli) 		4 / 7 ASP A  16
THR A  17
TYR A  18
HIS A  47
 None
 1.17A 3abmN-2gs4A:
2.8
3abmP-2gs4A:
4.0		 3abmN-2gs4A:
14.17
3abmP-2gs4A:
20.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG1_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 2gs4 PROTEIN YCIF
(Escherichia
coli) 		4 / 6 ASP A  16
THR A  17
TYR A  18
HIS A  47
 None
 1.25A 3ag1N-2gs4A:
2.5
3ag1P-2gs4A:
3.9		 3ag1N-2gs4A:
14.17
3ag1P-2gs4A:
20.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG2_A_CHDA525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 2gs4 PROTEIN YCIF
(Escherichia
coli) 		4 / 7 ASP A  16
THR A  17
TYR A  18
HIS A  47
 None
 1.24A 3ag2A-2gs4A:
2.4
3ag2C-2gs4A:
4.1		 3ag2A-2gs4A:
14.17
3ag2C-2gs4A:
20.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG2_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 2gs4 PROTEIN YCIF
(Escherichia
coli) 		4 / 7 ASP A  16
THR A  17
TYR A  18
HIS A  47
 None
 1.21A 3ag2N-2gs4A:
2.6
3ag2P-2gs4A:
3.8		 3ag2N-2gs4A:
14.17
3ag2P-2gs4A:
20.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG3_C_CHDC525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 2gs4 PROTEIN YCIF
(Escherichia
coli) 		4 / 7 ASP A  16
THR A  17
TYR A  18
HIS A  47
 None
 1.24A 3ag3A-2gs4A:
undetectable
3ag3C-2gs4A:
4.0		 3ag3A-2gs4A:
14.17
3ag3C-2gs4A:
20.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG3_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 2gs4 PROTEIN YCIF
(Escherichia
coli) 		4 / 7 ASP A  16
THR A  17
TYR A  18
HIS A  47
 None
 1.23A 3ag3N-2gs4A:
undetectable
3ag3P-2gs4A:
4.0		 3ag3N-2gs4A:
14.17
3ag3P-2gs4A:
20.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG4_C_CHDC525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 2gs4 PROTEIN YCIF
(Escherichia
coli) 		4 / 7 ASP A  16
THR A  17
TYR A  18
HIS A  47
 None
 1.23A 3ag4A-2gs4A:
2.4
3ag4C-2gs4A:
4.0		 3ag4A-2gs4A:
14.17
3ag4C-2gs4A:
20.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG4_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 2gs4 PROTEIN YCIF
(Escherichia
coli) 		4 / 7 ASP A  16
THR A  17
TYR A  18
HIS A  47
 None
 1.21A 3ag4N-2gs4A:
2.4
3ag4P-2gs4A:
4.0		 3ag4N-2gs4A:
14.17
3ag4P-2gs4A:
20.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASN_C_CHDC525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 2gs4 PROTEIN YCIF
(Escherichia
coli) 		4 / 6 ASP A  16
THR A  17
TYR A  18
HIS A  47
 None
 1.20A 3asnA-2gs4A:
undetectable
3asnC-2gs4A:
4.0		 3asnA-2gs4A:
14.17
3asnC-2gs4A:
20.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASO_C_CHDC525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 2gs4 PROTEIN YCIF
(Escherichia
coli) 		4 / 8 ASP A  16
THR A  17
TYR A  18
HIS A  47
 None
 1.21A 3asoA-2gs4A:
2.2
3asoC-2gs4A:
4.0
3asoP-2gs4A:
4.0		 3asoA-2gs4A:
14.17
3asoC-2gs4A:
20.32
3asoP-2gs4A:
20.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WG7_C_CHDC306_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 2gs4 PROTEIN YCIF
(Escherichia
coli) 		4 / 8 ASP A  16
THR A  17
TYR A  18
HIS A  47
 None
 1.19A 3wg7A-2gs4A:
undetectable
3wg7C-2gs4A:
4.0
3wg7P-2gs4A:
4.0		 3wg7A-2gs4A:
14.17
3wg7C-2gs4A:
20.32
3wg7P-2gs4A:
20.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WG7_P_CHDP307_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 2gs4 PROTEIN YCIF
(Escherichia
coli) 		4 / 8 ASP A  16
THR A  17
TYR A  18
HIS A  47
 None
 1.21A 3wg7C-2gs4A:
4.0
3wg7N-2gs4A:
undetectable
3wg7P-2gs4A:
4.1		 3wg7C-2gs4A:
20.32
3wg7N-2gs4A:
14.17
3wg7P-2gs4A:
20.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3X2Q_C_CHDC305_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 2gs4 PROTEIN YCIF
(Escherichia
coli) 		4 / 8 ASP A  16
THR A  17
TYR A  18
HIS A  47
 None
 1.17A 3x2qA-2gs4A:
2.6
3x2qC-2gs4A:
4.0
3x2qP-2gs4A:
3.9		 3x2qA-2gs4A:
14.17
3x2qC-2gs4A:
20.32
3x2qP-2gs4A:
20.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3X2Q_P_CHDP308_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 2gs4 PROTEIN YCIF
(Escherichia
coli) 		4 / 8 ASP A  16
THR A  17
TYR A  18
HIS A  47
 None
 1.18A 3x2qC-2gs4A:
4.0
3x2qN-2gs4A:
3.5
3x2qP-2gs4A:
4.0		 3x2qC-2gs4A:
20.32
3x2qN-2gs4A:
14.17
3x2qP-2gs4A:
20.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DU2_B_LDPB501_1
(CYTOCHROME P450 BM3
VARIANT B7)		 2gs4 PROTEIN YCIF
(Escherichia
coli) 		5 / 7 ALA A 106
PHE A  44
ALA A  43
LEU A 150
THR A 146
 None
 1.42A 4du2B-2gs4A:
undetectable		 4du2B-2gs4A:
18.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M2R_A_BZ1A302_2
(CARBONIC ANHYDRASE 2)		 2gs4 PROTEIN YCIF
(Escherichia
coli) 		4 / 4 HIS A 111
GLU A 143
HIS A  47
LEU A  31
 None
 1.41A 4m2rA-2gs4A:
undetectable		 4m2rA-2gs4A:
20.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1A_C_CHDC305_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 2gs4 PROTEIN YCIF
(Escherichia
coli) 		4 / 8 ASP A  16
THR A  17
TYR A  18
HIS A  47
 None
 1.20A 5b1aA-2gs4A:
undetectable
5b1aC-2gs4A:
4.1
5b1aP-2gs4A:
4.0		 5b1aA-2gs4A:
14.17
5b1aC-2gs4A:
20.32
5b1aP-2gs4A:
20.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1A_P_CHDP307_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 2gs4 PROTEIN YCIF
(Escherichia
coli) 		4 / 7 ASP A  16
THR A  17
TYR A  18
HIS A  47
 None
 1.19A 5b1aN-2gs4A:
undetectable
5b1aP-2gs4A:
4.0		 5b1aN-2gs4A:
14.17
5b1aP-2gs4A:
20.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1B_P_CHDP307_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 2gs4 PROTEIN YCIF
(Escherichia
coli) 		4 / 7 ASP A  16
THR A  17
TYR A  18
HIS A  47
 None
 1.20A 5b1bN-2gs4A:
3.3
5b1bP-2gs4A:
4.0		 5b1bN-2gs4A:
14.17
5b1bP-2gs4A:
20.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B3S_C_CHDC301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 2gs4 PROTEIN YCIF
(Escherichia
coli) 		4 / 8 ASP A  16
THR A  17
TYR A  18
HIS A  47
 None
 1.20A 5b3sA-2gs4A:
undetectable
5b3sC-2gs4A:
4.0
5b3sP-2gs4A:
3.0		 5b3sA-2gs4A:
14.17
5b3sC-2gs4A:
20.32
5b3sP-2gs4A:
20.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B3S_P_CHDP301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 2gs4 PROTEIN YCIF
(Escherichia
coli) 		4 / 7 ASP A  16
THR A  17
TYR A  18
HIS A  47
 None
 1.20A 5b3sN-2gs4A:
undetectable
5b3sP-2gs4A:
3.0		 5b3sN-2gs4A:
14.17
5b3sP-2gs4A:
20.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IY5_C_CHDC301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 2gs4 PROTEIN YCIF
(Escherichia
coli) 		4 / 7 ASP A  16
THR A  17
TYR A  18
HIS A  47
 None
 1.20A 5iy5A-2gs4A:
2.3
5iy5C-2gs4A:
4.0		 5iy5A-2gs4A:
14.17
5iy5C-2gs4A:
19.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IY5_P_CHDP301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 2gs4 PROTEIN YCIF
(Escherichia
coli) 		4 / 8 ASP A  16
THR A  17
TYR A  18
HIS A  47
 None
 1.18A 5iy5C-2gs4A:
4.0
5iy5N-2gs4A:
undetectable
5iy5P-2gs4A:
4.0		 5iy5C-2gs4A:
19.92
5iy5N-2gs4A:
14.17
5iy5P-2gs4A:
19.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X19_P_CHDP306_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 2gs4 PROTEIN YCIF
(Escherichia
coli) 		4 / 6 ASP A  16
THR A  17
TYR A  18
HIS A  47
 None
 1.18A 5x19N-2gs4A:
2.5
5x19P-2gs4A:
3.0		 5x19N-2gs4A:
14.17
5x19P-2gs4A:
20.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1B_P_CHDP306_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 2gs4 PROTEIN YCIF
(Escherichia
coli) 		4 / 6 ASP A  16
THR A  17
TYR A  18
HIS A  47
 None
 1.20A 5x1bN-2gs4A:
3.3
5x1bP-2gs4A:
3.8		 5x1bN-2gs4A:
14.17
5x1bP-2gs4A:
20.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1F_P_CHDP305_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 2gs4 PROTEIN YCIF
(Escherichia
coli) 		4 / 7 ASP A  16
THR A  17
TYR A  18
HIS A  47
 None
 1.24A 5x1fN-2gs4A:
2.4
5x1fP-2gs4A:
3.9		 5x1fN-2gs4A:
14.17
5x1fP-2gs4A:
20.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDQ_C_CHDC301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 2gs4 PROTEIN YCIF
(Escherichia
coli) 		4 / 8 ASP A  16
THR A  17
TYR A  18
HIS A  47
 None
 1.21A 5xdqA-2gs4A:
undetectable
5xdqC-2gs4A:
4.0
5xdqP-2gs4A:
4.0		 5xdqA-2gs4A:
14.17
5xdqC-2gs4A:
20.32
5xdqP-2gs4A:
20.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDQ_P_CHDP301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 2gs4 PROTEIN YCIF
(Escherichia
coli) 		4 / 8 ASP A  16
THR A  17
TYR A  18
HIS A  47
 None
 1.20A 5xdqC-2gs4A:
4.0
5xdqN-2gs4A:
undetectable
5xdqP-2gs4A:
3.9		 5xdqC-2gs4A:
20.32
5xdqN-2gs4A:
14.17
5xdqP-2gs4A:
20.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z84_C_CHDC301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 2gs4 PROTEIN YCIF
(Escherichia
coli) 		4 / 8 ASP A  16
THR A  17
TYR A  18
HIS A  47
 None
 1.17A 5z84A-2gs4A:
undetectable
5z84C-2gs4A:
4.1
5z84P-2gs4A:
4.0		 5z84A-2gs4A:
14.17
5z84C-2gs4A:
20.32
5z84P-2gs4A:
20.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z84_P_CHDP301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 2gs4 PROTEIN YCIF
(Escherichia
coli) 		4 / 7 ASP A  16
THR A  17
TYR A  18
HIS A  47
 None
 1.18A 5z84C-2gs4A:
4.0
5z84N-2gs4A:
undetectable
5z84P-2gs4A:
4.0		 5z84C-2gs4A:
20.32
5z84N-2gs4A:
14.17
5z84P-2gs4A:
20.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z85_C_CHDC301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 2gs4 PROTEIN YCIF
(Escherichia
coli) 		4 / 8 ASP A  16
THR A  17
TYR A  18
HIS A  47
 None
 1.18A 5z85A-2gs4A:
undetectable
5z85C-2gs4A:
4.0
5z85P-2gs4A:
4.0		 5z85A-2gs4A:
14.17
5z85C-2gs4A:
20.32
5z85P-2gs4A:
20.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z85_P_CHDP301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 2gs4 PROTEIN YCIF
(Escherichia
coli) 		4 / 7 ASP A  16
THR A  17
TYR A  18
HIS A  47
 None
 1.19A 5z85C-2gs4A:
4.0
5z85N-2gs4A:
undetectable
5z85P-2gs4A:
4.0		 5z85C-2gs4A:
20.32
5z85N-2gs4A:
14.17
5z85P-2gs4A:
20.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z86_C_CHDC301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 2gs4 PROTEIN YCIF
(Escherichia
coli) 		4 / 8 ASP A  16
THR A  17
TYR A  18
HIS A  47
 None
 1.19A 5z86A-2gs4A:
undetectable
5z86C-2gs4A:
4.0
5z86P-2gs4A:
3.0		 5z86A-2gs4A:
14.17
5z86C-2gs4A:
20.32
5z86P-2gs4A:
20.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z86_P_CHDP301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 2gs4 PROTEIN YCIF
(Escherichia
coli) 		4 / 8 ASP A  16
THR A  17
TYR A  18
HIS A  47
 None
 1.21A 5z86C-2gs4A:
4.0
5z86N-2gs4A:
2.3
5z86P-2gs4A:
3.0		 5z86C-2gs4A:
20.32
5z86N-2gs4A:
14.17
5z86P-2gs4A:
20.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCO_C_CHDC301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 2gs4 PROTEIN YCIF
(Escherichia
coli) 		4 / 8 ASP A  16
THR A  17
TYR A  18
HIS A  47
 None
 1.19A 5zcoA-2gs4A:
2.4
5zcoC-2gs4A:
3.9
5zcoP-2gs4A:
2.8		 5zcoA-2gs4A:
14.17
5zcoC-2gs4A:
20.32
5zcoP-2gs4A:
20.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCO_P_CHDP301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 2gs4 PROTEIN YCIF
(Escherichia
coli) 		4 / 8 ASP A  16
THR A  17
TYR A  18
HIS A  47
 None
 1.21A 5zcoC-2gs4A:
4.0
5zcoN-2gs4A:
undetectable
5zcoP-2gs4A:
2.8		 5zcoC-2gs4A:
20.32
5zcoN-2gs4A:
14.17
5zcoP-2gs4A:
20.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCP_C_CHDC301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 2gs4 PROTEIN YCIF
(Escherichia
coli) 		4 / 8 ASP A  16
THR A  17
TYR A  18
HIS A  47
 None
 1.19A 5zcpA-2gs4A:
2.4
5zcpC-2gs4A:
4.0
5zcpP-2gs4A:
3.9		 5zcpA-2gs4A:
14.17
5zcpC-2gs4A:
20.32
5zcpP-2gs4A:
20.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCP_P_CHDP301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 2gs4 PROTEIN YCIF
(Escherichia
coli) 		4 / 8 ASP A  16
THR A  17
TYR A  18
HIS A  47
 None
 1.20A 5zcpC-2gs4A:
4.0
5zcpN-2gs4A:
undetectable
5zcpP-2gs4A:
4.0		 5zcpC-2gs4A:
20.32
5zcpN-2gs4A:
14.17
5zcpP-2gs4A:
20.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCQ_C_CHDC301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 2gs4 PROTEIN YCIF
(Escherichia
coli) 		4 / 8 ASP A  16
THR A  17
TYR A  18
HIS A  47
 None
 1.18A 5zcqA-2gs4A:
2.4
5zcqC-2gs4A:
4.0
5zcqP-2gs4A:
4.0		 5zcqA-2gs4A:
14.17
5zcqC-2gs4A:
20.32
5zcqP-2gs4A:
20.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCQ_P_CHDP301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 2gs4 PROTEIN YCIF
(Escherichia
coli) 		4 / 7 ASP A  16
THR A  17
TYR A  18
HIS A  47
 None
 1.19A 5zcqN-2gs4A:
2.4
5zcqP-2gs4A:
4.0		 5zcqN-2gs4A:
14.17
5zcqP-2gs4A:
20.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NKN_C_CHDC301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 2gs4 PROTEIN YCIF
(Escherichia
coli) 		4 / 6 ASP A  16
THR A  17
TYR A  18
HIS A  47
 None
 1.20A 6nknA-2gs4A:
1.8
6nknC-2gs4A:
3.9		 6nknA-2gs4A:
14.17
6nknC-2gs4A:
20.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NMF_C_CHDC306_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 2gs4 PROTEIN YCIF
(Escherichia
coli) 		4 / 7 ASP A  16
THR A  17
TYR A  18
HIS A  47
 None
 1.21A 6nmfA-2gs4A:
undetectable
6nmfC-2gs4A:
3.9
6nmfP-2gs4A:
3.9		 6nmfA-2gs4A:
14.17
6nmfC-2gs4A:
20.32
6nmfP-2gs4A:
20.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NMP_C_CHDC303_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 2gs4 PROTEIN YCIF
(Escherichia
coli) 		4 / 6 ASP A  16
THR A  17
TYR A  18
HIS A  47
 None
 1.17A 6nmpA-2gs4A:
2.1
6nmpC-2gs4A:
4.0		 6nmpA-2gs4A:
14.17
6nmpC-2gs4A:
20.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NMP_P_CHDP302_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 2gs4 PROTEIN YCIF
(Escherichia
coli) 		4 / 7 ASP A  16
THR A  17
TYR A  18
HIS A  47
 None
 1.20A 6nmpN-2gs4A:
2.1
6nmpP-2gs4A:
4.0		 6nmpN-2gs4A:
14.17
6nmpP-2gs4A:
20.32