SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2gs5'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JGS_A_SALA256_1
(MULTIPLE ANTIBIOTIC
RESISTANCE PROTEIN
MARR)		 2gs5 CONSERVED
HYPOTHETICAL PROTEIN
(Corynebacterium
diphtheriae) 		4 / 7 VAL A  91
LEU A 109
THR A 107
LEU A 106
 None
 0.91A 1jgsA-2gs5A:
undetectable		 1jgsA-2gs5A:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q23_B_FUAB703_1
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 2gs5 CONSERVED
HYPOTHETICAL PROTEIN
(Corynebacterium
diphtheriae) 		5 / 12 THR A  94
LEU A  38
VAL A  50
PHE A 135
VAL A 165
 None
 1.12A 1q23B-2gs5A:
undetectable		 1q23B-2gs5A:
18.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q23_C_FUAC701_2
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 2gs5 CONSERVED
HYPOTHETICAL PROTEIN
(Corynebacterium
diphtheriae) 		5 / 12 THR A  94
LEU A  38
VAL A  50
PHE A 135
VAL A 165
 None
 1.20A 1q23C-2gs5A:
undetectable		 1q23C-2gs5A:
18.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q23_I_FUAI707_2
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 2gs5 CONSERVED
HYPOTHETICAL PROTEIN
(Corynebacterium
diphtheriae) 		5 / 11 THR A  94
LEU A  38
VAL A  50
PHE A 135
VAL A 165
 None
 1.24A 1q23I-2gs5A:
undetectable		 1q23I-2gs5A:
18.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q23_K_FUAK712_1
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 2gs5 CONSERVED
HYPOTHETICAL PROTEIN
(Corynebacterium
diphtheriae) 		5 / 10 THR A  94
LEU A  38
VAL A  50
PHE A 135
VAL A 165
 None
 1.17A 1q23K-2gs5A:
undetectable		 1q23K-2gs5A:
18.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q23_L_FUAL710_2
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 2gs5 CONSERVED
HYPOTHETICAL PROTEIN
(Corynebacterium
diphtheriae) 		5 / 11 THR A  94
LEU A  38
VAL A  50
PHE A 135
VAL A 165
 None
 1.15A 1q23L-2gs5A:
undetectable		 1q23L-2gs5A:
18.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TL9_A_ROCA401_4
(PROTEASE)		 2gs5 CONSERVED
HYPOTHETICAL PROTEIN
(Corynebacterium
diphtheriae) 		4 / 4 ASP A 172
ASP A 176
GLY A 169
THR A 166
 None
 1.38A 3tl9B-2gs5A:
undetectable		 3tl9B-2gs5A:
22.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U9F_B_CLMB221_0
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 2gs5 CONSERVED
HYPOTHETICAL PROTEIN
(Corynebacterium
diphtheriae) 		5 / 12 THR A  94
LEU A  38
VAL A  50
PHE A 135
VAL A 165
 None
 1.21A 3u9fB-2gs5A:
undetectable
3u9fC-2gs5A:
undetectable		 3u9fB-2gs5A:
18.45
3u9fC-2gs5A:
18.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U9F_H_CLMH221_0
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 2gs5 CONSERVED
HYPOTHETICAL PROTEIN
(Corynebacterium
diphtheriae) 		5 / 12 THR A  94
LEU A  38
VAL A  50
PHE A 135
VAL A 165
 None
 1.21A 3u9fH-2gs5A:
undetectable
3u9fI-2gs5A:
undetectable		 3u9fH-2gs5A:
18.45
3u9fI-2gs5A:
18.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U9F_S_CLMS221_0
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 2gs5 CONSERVED
HYPOTHETICAL PROTEIN
(Corynebacterium
diphtheriae) 		5 / 12 THR A  94
LEU A  38
VAL A  50
PHE A 135
VAL A 165
 None
 1.23A 3u9fP-2gs5A:
undetectable
3u9fS-2gs5A:
undetectable		 3u9fP-2gs5A:
18.45
3u9fS-2gs5A:
18.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ACB_B_DXCB1473_0
(TRANSLATION
ELONGATION FACTOR
SELB)		 2gs5 CONSERVED
HYPOTHETICAL PROTEIN
(Corynebacterium
diphtheriae) 		4 / 8 ILE A  79
GLY A  81
VAL A  58
GLN A  86
 None
 0.87A 4acbB-2gs5A:
undetectable
4acbC-2gs5A:
undetectable		 4acbB-2gs5A:
18.39
4acbC-2gs5A:
18.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5C6P_A_4YHA601_1
(PROTEIN C)		 2gs5 CONSERVED
HYPOTHETICAL PROTEIN
(Corynebacterium
diphtheriae) 		4 / 6 ALA A 167
SER A 163
ASP A 172
PRO A 192
 None
 1.17A 5c6pA-2gs5A:
undetectable		 5c6pA-2gs5A:
17.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ECL_A_ILEA602_0
(JASMONIC ACID-AMIDO
SYNTHETASE JAR1)		 2gs5 CONSERVED
HYPOTHETICAL PROTEIN
(Corynebacterium
diphtheriae) 		4 / 6 ALA A  95
THR A  94
VAL A  98
VAL A 116
 None
 1.00A 5eclA-2gs5A:
undetectable		 5eclA-2gs5A:
19.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I8F_A_ML1A211_1
(PHENOLIC OXIDATIVE
COUPLING PROTEIN)		 2gs5 CONSERVED
HYPOTHETICAL PROTEIN
(Corynebacterium
diphtheriae) 		4 / 6 VAL A  20
ALA A 158
GLN A 181
VAL A 177
 None
 0.93A 5i8fA-2gs5A:
undetectable		 5i8fA-2gs5A:
21.05