SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2gsb'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JKJ_D_CLMD1142_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 2gsb RAS
GTPASE-ACTIVATING
PROTEIN 1
(Homo
sapiens) 		4 / 5 PRO A  45
PRO A  50
GLY A  51
TYR A  53
 None
 1.05A 2jkjD-2gsbA:
undetectable		 2jkjD-2gsbA:
24.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JKJ_F_CLMF1143_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 2gsb RAS
GTPASE-ACTIVATING
PROTEIN 1
(Homo
sapiens) 		4 / 5 PRO A  45
PRO A  50
GLY A  51
TYR A  53
 None
 1.06A 2jkjF-2gsbA:
undetectable		 2jkjF-2gsbA:
24.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LSF_B_PZIB802_0
(GLUTAMATE RECEPTOR 2)		 2gsb RAS
GTPASE-ACTIVATING
PROTEIN 1
(Homo
sapiens) 		3 / 3 SER A  24
ASP A  47
ASN A  48
 None
 0.98A 3lsfB-2gsbA:
undetectable
3lsfE-2gsbA:
undetectable		 3lsfB-2gsbA:
18.52
3lsfE-2gsbA:
18.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LSF_E_PZIE802_0
(GLUTAMATE RECEPTOR 2)		 2gsb RAS
GTPASE-ACTIVATING
PROTEIN 1
(Homo
sapiens) 		3 / 3 ASP A  47
ASN A  48
SER A  24
 None
 0.95A 3lsfB-2gsbA:
undetectable
3lsfE-2gsbA:
undetectable		 3lsfB-2gsbA:
18.52
3lsfE-2gsbA:
18.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LB2_B_DM5B601_1
(SERUM ALBUMIN)		 2gsb RAS
GTPASE-ACTIVATING
PROTEIN 1
(Homo
sapiens) 		5 / 9 LEU A  42
VAL A  43
PRO A  45
TYR A  29
ILE A  63
 None
 1.22A 4lb2B-2gsbA:
undetectable		 4lb2B-2gsbA:
9.76