SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2gsc'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2VQ5_B_LDPB1197_1 (S-NORCOCLAURINE SYNTHASE)	2gsc	PUTATIVE UNCHARACTERIZED PROTEIN XCC0516 (Xanthomonas campestris)	4 / 7	LEU A 42 LEU A 46 PHE A 34 LEU A 93	None	0.87A	2vq5B-2gscA: undetectable	2vq5B-2gscA: 17.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3B9M_A_SALA1100_1 (SERUM ALBUMIN)	2gsc	PUTATIVE UNCHARACTERIZED PROTEIN XCC0516 (Xanthomonas campestris)	4 / 4	LEU A 14 ARG A 124 LEU A 122 ALA A 117	None	1.12A	3b9mA-2gscA: 3.8	3b9mA-2gscA: 13.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3ELZ_A_CHDA152_0 (ILEAL BILE ACID-BINDING PROTEIN)	2gsc	PUTATIVE UNCHARACTERIZED PROTEIN XCC0516 (Xanthomonas campestris)	3 / 3	VAL A 111 LYS A 114 HIS A 11	None	0.80A	3elzA-2gscA: undetectable	3elzA-2gscA: 20.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3LBD_A_9CRA424_1 (RETINOIC ACID RECEPTOR GAMMA)	2gsc	PUTATIVE UNCHARACTERIZED PROTEIN XCC0516 (Xanthomonas campestris)	5 / 12	ALA A 76 LEU A 118 LEU A 115 SER A 81 ALA A 61	None	1.37A	3lbdA-2gscA: undetectable	3lbdA-2gscA: 19.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4IKI_A_IMNA201_1 (TRANSTHYRETIN)	2gsc	PUTATIVE UNCHARACTERIZED PROTEIN XCC0516 (Xanthomonas campestris)	3 / 3	LYS A 114 LEU A 110 ALA A 113	None	0.62A	4ikiA-2gscA: undetectable	4ikiA-2gscA: 21.77

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["2VQ5_B_LDPB1197_1","S-NORCOCLAURINE SYNTHASE","2gsc","PUTATIVE UNCHARACTERIZED PROTEIN XCC0516","Xanthomonas campestris",4,"LEU A  42;LEU A  46;PHE A  34;LEU A  93","None","0.87A","2vq5B-2gscA:undetectable","2vq5B-2gscA:17.71"],["3B9M_A_SALA1100_1","SERUM ALBUMIN","2gsc","PUTATIVE UNCHARACTERIZED PROTEIN XCC0516","Xanthomonas campestris",4,"LEU A  14;ARG A 124;LEU A 122;ALA A 117","None","1.12A","3b9mA-2gscA:3.8","3b9mA-2gscA:13.36"],["3ELZ_A_CHDA152_0","ILEAL BILE ACID-BINDING PROTEIN","2gsc","PUTATIVE UNCHARACTERIZED PROTEIN XCC0516","Xanthomonas campestris",3,"VAL A 111;LYS A 114;HIS A  11","None","0.80A","3elzA-2gscA:undetectable","3elzA-2gscA:20.41"],["3LBD_A_9CRA424_1","RETINOIC ACID RECEPTOR GAMMA","2gsc","PUTATIVE UNCHARACTERIZED PROTEIN XCC0516","Xanthomonas campestris",5,"ALA A  76;LEU A 118;LEU A 115;SER A  81;ALA A  61","None","1.37A","3lbdA-2gscA:undetectable","3lbdA-2gscA:19.50"],["4IKI_A_IMNA201_1","TRANSTHYRETIN","2gsc","PUTATIVE UNCHARACTERIZED PROTEIN XCC0516","Xanthomonas campestris",3,"LYS A 114;LEU A 110;ALA A 113","None","0.62A","4ikiA-2gscA:undetectable","4ikiA-2gscA:21.77"]]