SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2gsj'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FM4_A_DXCA1002_0
(MAJOR POLLEN
ALLERGEN BET V 1-L)		 2gsj PROTEIN PPL-2
(Parkia
platycephala) 		5 / 12 TYR A   6
VAL A   4
ILE A  27
ASN A  29
LEU A 165
 None
 1.18A 1fm4A-2gsjA:
undetectable		 1fm4A-2gsjA:
19.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L2I_B_CCSB417_0
(ESTROGEN RECEPTOR)		 2gsj PROTEIN PPL-2
(Parkia
platycephala) 		4 / 6 PRO A 194
PHE A 189
GLN A 236
VAL A 241
 None
 1.37A 1l2iB-2gsjA:
undetectable		 1l2iB-2gsjA:
21.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3A_A_TEPA1433_1
(CHITINASE)		 2gsj PROTEIN PPL-2
(Parkia
platycephala) 		6 / 11 TYR A   6
PHE A  32
GLY A  80
GLU A 127
TYR A 182
TRP A 253
 None
 0.55A 2a3aA-2gsjA:
19.7		 2a3aA-2gsjA:
23.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3A_B_TEPB2433_1
(CHITINASE)		 2gsj PROTEIN PPL-2
(Parkia
platycephala) 		5 / 9 PHE A  32
GLY A  80
GLU A 127
TYR A 182
TRP A 253
 None
 0.56A 2a3aB-2gsjA:
19.6		 2a3aB-2gsjA:
23.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3B_B_CFFB2435_1
(CHITINASE)		 2gsj PROTEIN PPL-2
(Parkia
platycephala) 		6 / 10 PHE A  32
GLY A  80
ASP A 125
GLU A 127
TYR A 182
TRP A 253
 None
 1.11A 2a3bB-2gsjA:
19.6		 2a3bB-2gsjA:
23.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3C_A_PNXA1434_1
(CHITINASE)		 2gsj PROTEIN PPL-2
(Parkia
platycephala) 		7 / 12 TYR A   6
PHE A  32
GLY A  80
ASP A 125
GLU A 127
TYR A 182
TRP A 253
 None
 1.14A 2a3cA-2gsjA:
19.7		 2a3cA-2gsjA:
23.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3C_B_PNXB2433_1
(CHITINASE)		 2gsj PROTEIN PPL-2
(Parkia
platycephala) 		6 / 12 PHE A  32
GLY A  80
ASP A 125
GLU A 127
TYR A 182
TRP A 253
 None
 1.11A 2a3cB-2gsjA:
19.7		 2a3cB-2gsjA:
23.77
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2UY4_A_AZMA1311_1
(ENDOCHITINASE)		 2gsj PROTEIN PPL-2
(Parkia
platycephala) 		6 / 9 TYR A   6
PHE A  32
ASP A 125
GLN A 180
TYR A 182
TRP A 253
 None
 0.97A 2uy4A-2gsjA:
36.8		 2uy4A-2gsjA:
36.88
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2UY4_A_AZMA1311_1
(ENDOCHITINASE)		 2gsj PROTEIN PPL-2
(Parkia
platycephala) 		7 / 9 TYR A   6
PHE A  32
GLY A  80
ASP A 125
GLU A 127
TYR A 182
TRP A 253
 None
 0.38A 2uy4A-2gsjA:
36.8		 2uy4A-2gsjA:
36.88
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2XTK_A_AZMA1339_1
(CLASS III CHITINASE
CHIA1)		 2gsj PROTEIN PPL-2
(Parkia
platycephala) 		6 / 11 GLY A  81
GLU A 127
TYR A 182
ASN A 183
ALA A 223
TRP A 253
 None
 1.16A 2xtkA-2gsjA:
36.0		 2xtkA-2gsjA:
34.09
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2XTK_A_AZMA1339_1
(CLASS III CHITINASE
CHIA1)		 2gsj PROTEIN PPL-2
(Parkia
platycephala) 		6 / 11 PHE A  32
GLY A  80
GLU A 127
GLN A 157
ASN A 183
ALA A 223
 None
 1.23A 2xtkA-2gsjA:
36.0		 2xtkA-2gsjA:
34.09
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2XTK_A_AZMA1339_1
(CLASS III CHITINASE
CHIA1)		 2gsj PROTEIN PPL-2
(Parkia
platycephala) 		7 / 11 TYR A   6
PHE A  32
ASP A 125
GLN A 180
TYR A 182
ALA A 223
TRP A 253
 None
 0.97A 2xtkA-2gsjA:
36.0		 2xtkA-2gsjA:
34.09
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2XTK_A_AZMA1339_1
(CLASS III CHITINASE
CHIA1)		 2gsj PROTEIN PPL-2
(Parkia
platycephala) 		9 / 11 TYR A   6
PHE A  32
GLY A  80
ASP A 125
GLU A 127
TYR A 182
ASN A 183
ALA A 223
TRP A 253
 None
 0.60A 2xtkA-2gsjA:
36.0		 2xtkA-2gsjA:
34.09
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2XTK_A_AZMA1339_1
(CLASS III CHITINASE
CHIA1)		 2gsj PROTEIN PPL-2
(Parkia
platycephala) 		7 / 11 TYR A   6
PHE A  32
GLY A  80
ASP A 125
TYR A 182
ALA A 222
TRP A 253
 None
 1.10A 2xtkA-2gsjA:
36.0		 2xtkA-2gsjA:
34.09
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2XTK_B_AZMB1339_1
(CLASS III CHITINASE
CHIA1)		 2gsj PROTEIN PPL-2
(Parkia
platycephala) 		6 / 10 TYR A   6
PHE A  32
ASP A 125
GLN A 180
TYR A 182
TRP A 253
 None
 0.96A 2xtkB-2gsjA:
36.1		 2xtkB-2gsjA:
34.09
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2XTK_B_AZMB1339_1
(CLASS III CHITINASE
CHIA1)		 2gsj PROTEIN PPL-2
(Parkia
platycephala) 		7 / 10 TYR A   6
PHE A  32
GLY A  80
ASP A 125
GLU A 127
TYR A 182
TRP A 253
 None
 0.39A 2xtkB-2gsjA:
36.1		 2xtkB-2gsjA:
34.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FPJ_A_SAMA301_0
(PUTATIVE
UNCHARACTERIZED
PROTEIN)		 2gsj PROTEIN PPL-2
(Parkia
platycephala) 		5 / 12 ILE A  64
GLY A  63
VAL A  60
ALA A  66
VAL A  74
 None
 1.01A 3fpjA-2gsjA:
undetectable		 3fpjA-2gsjA:
21.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FRQ_A_ERYA195_0
(REPRESSOR PROTEIN
MPHR(A))		 2gsj PROTEIN PPL-2
(Parkia
platycephala) 		5 / 12 VAL A 271
LEU A 233
SER A  22
VAL A 250
THR A 261
 None
 1.18A 3frqA-2gsjA:
undetectable		 3frqA-2gsjA:
20.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G6M_A_CFFA1_1
(CHITINASE)		 2gsj PROTEIN PPL-2
(Parkia
platycephala) 		6 / 11 TYR A   6
PHE A  32
GLY A  80
GLU A 127
TYR A 182
TRP A 253
 None
 0.64A 3g6mA-2gsjA:
20.1		 3g6mA-2gsjA:
22.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HAV_A_SRYA403_1
(AMINOGLYCOSIDE
PHOSPHOTRANSFERASE)		 2gsj PROTEIN PPL-2
(Parkia
platycephala) 		4 / 8 ASP A 123
ASP A 125
ASP A 258
TYR A 182
 None
 0.99A 3havA-2gsjA:
undetectable		 3havA-2gsjA:
21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LOQ_A_ACTA277_0
(UNIVERSAL STRESS
PROTEIN)		 2gsj PROTEIN PPL-2
(Parkia
platycephala) 		3 / 3 ASP A  92
SER A  88
ARG A  40
 None
 1.02A 3loqA-2gsjA:
undetectable		 3loqA-2gsjA:
22.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NK2_X_LDPX433_1
(6-HYDROXY-L-NICOTINE
OXIDASE)		 2gsj PROTEIN PPL-2
(Parkia
platycephala) 		4 / 7 TYR A 133
LEU A 105
LEU A 136
PHE A  36
 None
 1.02A 3nk2X-2gsjA:
undetectable		 3nk2X-2gsjA:
20.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PMZ_E_TUBE220_1
(SOLUBLE
ACETYLCHOLINE
RECEPTOR)		 2gsj PROTEIN PPL-2
(Parkia
platycephala) 		4 / 6 TYR A  25
GLN A  26
ILE A  72
SER A 264
 None
 1.26A 3pmzD-2gsjA:
undetectable		 3pmzD-2gsjA:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WQV_A_GCSA501_1
(CHITINASE)		 2gsj PROTEIN PPL-2
(Parkia
platycephala) 		6 / 11 PHE A  32
GLY A  80
ASP A 125
GLU A 127
TYR A 182
TRP A 253
 None
 0.53A 3wqvA-2gsjA:
19.7		 3wqvA-2gsjA:
22.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WQW_A_GCSA501_1
(CHITINASE)		 2gsj PROTEIN PPL-2
(Parkia
platycephala) 		6 / 11 PHE A  32
GLY A  80
ASP A 125
GLU A 127
TYR A 182
TRP A 253
 None
 0.54A 3wqwA-2gsjA:
19.7		 3wqwA-2gsjA:
22.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PST_A_FOLA201_1
(DIHYDROFOLATE
REDUCTASE)		 2gsj PROTEIN PPL-2
(Parkia
platycephala) 		3 / 3 ILE A  64
ASP A 120
ARG A 112
 None
 0.81A 4pstA-2gsjA:
undetectable		 4pstA-2gsjA:
18.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QZU_B_RTLB201_0
(RETINOL-BINDING
PROTEIN 2)		 2gsj PROTEIN PPL-2
(Parkia
platycephala) 		5 / 12 PHE A 124
ALA A 137
ARG A  94
LEU A  87
LEU A  33
 None
 1.35A 4qzuB-2gsjA:
0.0		 4qzuB-2gsjA:
21.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XEY_A_1N1A601_2
(TYROSINE-PROTEIN
KINASE ABL1)		 2gsj PROTEIN PPL-2
(Parkia
platycephala) 		3 / 3 MET A 251
ASP A 125
PHE A 124
 None
 0.89A 4xeyA-2gsjA:
undetectable		 4xeyA-2gsjA:
21.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XEY_B_1N1B601_2
(TYROSINE-PROTEIN
KINASE ABL1)		 2gsj PROTEIN PPL-2
(Parkia
platycephala) 		3 / 3 MET A 251
ASP A 125
PHE A 124
 None
 0.86A 4xeyB-2gsjA:
undetectable		 4xeyB-2gsjA:
21.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5F9Z_B_HFGB703_0
(AMINOACYL-TRNA
SYNTHETASE)		 2gsj PROTEIN PPL-2
(Parkia
platycephala) 		5 / 12 LEU A 169
PHE A 174
VAL A 177
PRO A 156
GLY A  81
 None
 1.19A 5f9zB-2gsjA:
undetectable		 5f9zB-2gsjA:
17.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GQB_A_GCSA603_1
(CHITINASE)		 2gsj PROTEIN PPL-2
(Parkia
platycephala) 		5 / 8 PHE A  32
GLY A  80
GLU A 127
TYR A 182
TRP A 253
 None
 0.52A 5gqbA-2gsjA:
10.1		 5gqbA-2gsjA:
20.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IGV_A_ZITA404_2
(MACROLIDE
2'-PHOSPHOTRANSFERAS
E II)		 2gsj PROTEIN PPL-2
(Parkia
platycephala) 		4 / 4 ASN A 235
ILE A   3
TYR A 263
PHE A 181
 None
 1.44A 5igvA-2gsjA:
undetectable		 5igvA-2gsjA:
19.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TWJ_B_SAMB201_0
(RIBOSOMAL RNA LARGE
SUBUNIT
METHYLTRANSFERASE H)		 2gsj PROTEIN PPL-2
(Parkia
platycephala) 		5 / 10 ILE A  78
LEU A 140
SER A 141
LEU A 152
VAL A 122
 None
 1.12A 5twjB-2gsjA:
undetectable		 5twjB-2gsjA:
19.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TWJ_C_SAMC201_0
(RIBOSOMAL RNA LARGE
SUBUNIT
METHYLTRANSFERASE H)		 2gsj PROTEIN PPL-2
(Parkia
platycephala) 		5 / 12 ILE A  78
LEU A 140
SER A 141
LEU A 152
VAL A 122
 None
 1.13A 5twjC-2gsjA:
undetectable		 5twjC-2gsjA:
19.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X80_C_SALC201_1
(UNCHARACTERIZED
HTH-TYPE
TRANSCRIPTIONAL
REGULATOR RV2887)		 2gsj PROTEIN PPL-2
(Parkia
platycephala) 		4 / 7 ARG A  70
ARG A 255
VAL A  28
GLY A  23
 SO4  A1001 (-2.3A)
None
None
None
 0.87A 5x80C-2gsjA:
undetectable
5x80D-2gsjA:
undetectable		 5x80C-2gsjA:
21.48
5x80D-2gsjA:
21.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6F6S_A_CXQA507_1
(ENVELOPE
GLYCOPROTEIN,ENVELOP
E GLYCOPROTEIN,GP1
ENVELOPE
GLYCOPROTEIN)		 2gsj PROTEIN PPL-2
(Parkia
platycephala) 		4 / 5 ARG A  94
ALA A  93
TYR A 132
GLN A  91
 None
 1.12A 6f6sA-2gsjA:
undetectable
6f6sB-2gsjA:
undetectable		 6f6sA-2gsjA:
16.33
6f6sB-2gsjA:
13.41