SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2gt2'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HZQ_A_STRA300_1
(APOLIPOPROTEIN D)		 2gt2 GDP-MANNOSE MANNOSYL
HYDROLASE
(Escherichia
coli) 		4 / 7 THR A 101
ALA A 143
ASN A 144
PHE A  47
 None
 0.95A 2hzqA-2gt2A:
undetectable		 2hzqA-2gt2A:
22.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IZQ_C_DVAC8_0
(GRAMICIDIN D)		 2gt2 GDP-MANNOSE MANNOSYL
HYDROLASE
(Escherichia
coli) 		3 / 3 VAL A  48
TRP A  46
VAL A 141
 None
 0.96A 2izqC-2gt2A:
undetectable
2izqD-2gt2A:
undetectable		 2izqC-2gt2A:
7.58
2izqD-2gt2A:
7.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VQ5_B_LDPB1197_1
(S-NORCOCLAURINE
SYNTHASE)		 2gt2 GDP-MANNOSE MANNOSYL
HYDROLASE
(Escherichia
coli) 		4 / 7 LEU A  21
LEU A 106
PHE A 108
GLU A  60
 None
 0.93A 2vq5B-2gt2A:
undetectable		 2vq5B-2gt2A:
20.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UUN_B_ACTB307_0
(GLUTATHIONE
S-TRANSFERASE-LIKE
PROTEIN)		 2gt2 GDP-MANNOSE MANNOSYL
HYDROLASE
(Escherichia
coli) 		3 / 3 LEU A 150
ALA A 151
LEU A 136
 None
 0.21A 5uunB-2gt2A:
undetectable		 5uunB-2gt2A:
19.26