SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2gu1'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z2B_C_VLBC800_1
(TUBULIN BETA CHAIN
TUBULIN ALPHA CHAIN)		 2gu1 ZINC PEPTIDASE
(Vibrio
cholerae) 		4 / 8 VAL A 245
ASP A 207
TYR A 278
LEU A 281
 None
 0.96A 1z2bB-2gu1A:
undetectable		 1z2bB-2gu1A:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q0I_A_BEZA990_0
(QUINOLONE SIGNAL
RESPONSE PROTEIN)		 2gu1 ZINC PEPTIDASE
(Vibrio
cholerae) 		4 / 8 ASP A 236
GLU A 315
HIS A 232
LEU A  40
 ZN  A 362 (-2.1A)
None
ZN  A 362 (-3.2A)
None
 1.01A 2q0iA-2gu1A:
undetectable		 2q0iA-2gu1A:
21.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q0J_A_BEZA500_0
(QUINOLONE SIGNAL
RESPONSE PROTEIN)		 2gu1 ZINC PEPTIDASE
(Vibrio
cholerae) 		5 / 10 HIS A 311
ASP A 236
GLU A 315
HIS A 232
LEU A  40
 None
ZN  A 362 (-2.1A)
None
ZN  A 362 (-3.2A)
None
 1.22A 2q0jA-2gu1A:
0.0		 2q0jA-2gu1A:
20.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q0J_B_BEZB500_0
(QUINOLONE SIGNAL
RESPONSE PROTEIN)		 2gu1 ZINC PEPTIDASE
(Vibrio
cholerae) 		5 / 11 HIS A 311
ASP A 236
GLU A 315
HIS A 232
LEU A  40
 None
ZN  A 362 (-2.1A)
None
ZN  A 362 (-3.2A)
None
 1.18A 2q0jB-2gu1A:
undetectable		 2q0jB-2gu1A:
20.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3C0Z_A_SHHA301_1
(HISTONE DEACETYLASE
7A)		 2gu1 ZINC PEPTIDASE
(Vibrio
cholerae) 		4 / 5 HIS A 311
HIS A 280
ASP A 236
HIS A 313
 None
None
ZN  A 362 (-2.1A)
ZN  A 362 (-3.1A)
 1.03A 3c0zA-2gu1A:
undetectable		 3c0zA-2gu1A:
23.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3C0Z_C_SHHC301_1
(HISTONE DEACETYLASE
7A)		 2gu1 ZINC PEPTIDASE
(Vibrio
cholerae) 		4 / 6 HIS A 311
HIS A 280
ASP A 236
HIS A 313
 None
None
ZN  A 362 (-2.1A)
ZN  A 362 (-3.1A)
 1.04A 3c0zC-2gu1A:
undetectable		 3c0zC-2gu1A:
23.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IV6_A_SAMA301_0
(PUTATIVE
ZN-DEPENDENT ALCOHOL
DEHYDROGENASE)		 2gu1 ZINC PEPTIDASE
(Vibrio
cholerae) 		5 / 12 PHE A 103
GLY A 105
PHE A 172
SER A 171
ILE A 107
 None
 1.23A 3iv6A-2gu1A:
undetectable		 3iv6A-2gu1A:
22.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4G1B_C_ECNC403_1
(FLAVOHEMOGLOBIN)		 2gu1 ZINC PEPTIDASE
(Vibrio
cholerae) 		5 / 9 ILE A  35
TYR A  89
GLN A  44
LEU A  45
LEU A  67
 None
 1.19A 4g1bC-2gu1A:
undetectable		 4g1bC-2gu1A:
22.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JLC_A_1YNA602_2
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 2gu1 ZINC PEPTIDASE
(Vibrio
cholerae) 		4 / 5 GLY A 309
THR A 308
GLY A 295
LEU A 281
 None
 0.79A 5jlcA-2gu1A:
undetectable		 5jlcA-2gu1A:
19.39