SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2gu9'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OYA_A_RLTA398_1
(PFV INTEGRASE)		 2gu9 TETRACENOMYCIN
POLYKETIDE SYNTHESIS
PROTEIN
(Xanthomonas
campestris) 		4 / 8 ASP A  45
TYR A  96
PRO A  98
GLN A  20
 None
 1.15A 3oyaA-2gu9A:
undetectable		 3oyaA-2gu9A:
14.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S3M_A_DLUA398_1
(PFV INTEGRASE)		 2gu9 TETRACENOMYCIN
POLYKETIDE SYNTHESIS
PROTEIN
(Xanthomonas
campestris) 		4 / 8 ASP A  45
TYR A  96
PRO A  98
GLN A  20
 None
 1.04A 3s3mA-2gu9A:
undetectable		 3s3mA-2gu9A:
14.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S3O_A_DLUA399_1
(PFV INTEGRASE)		 2gu9 TETRACENOMYCIN
POLYKETIDE SYNTHESIS
PROTEIN
(Xanthomonas
campestris) 		4 / 7 ASP A  45
TYR A  96
PRO A  98
GLN A  20
 None
 1.01A 3s3oA-2gu9A:
undetectable		 3s3oA-2gu9A:
14.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FGL_A_CLQA303_0
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 2gu9 TETRACENOMYCIN
POLYKETIDE SYNTHESIS
PROTEIN
(Xanthomonas
campestris) 		5 / 12 GLY A  36
TYR A 101
ILE A  82
GLN A  78
ILE A  74
 None
 1.28A 4fglA-2gu9A:
undetectable
4fglB-2gu9A:
undetectable		 4fglA-2gu9A:
19.57
4fglB-2gu9A:
19.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CZM_D_HISD402_0
(ATP
PHOSPHORIBOSYLTRANSF
ERASE CATALYTIC
SUBUNIT)		 2gu9 TETRACENOMYCIN
POLYKETIDE SYNTHESIS
PROTEIN
(Xanthomonas
campestris) 		4 / 8 GLY A  55
LEU A  66
GLN A  67
LEU A  48
 None
 0.82A 6czmD-2gu9A:
undetectable
6czmF-2gu9A:
undetectable		 6czmD-2gu9A:
17.33
6czmF-2gu9A:
17.33