SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2gup'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

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	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	11GS_A_EAAA211_1 (GLUTATHIONE S-TRANSFERASE)	2gup	ROK FAMILY PROTEIN (Streptococcus pneumoniae)	4 / 7	TYR A 78 VAL A 76 ILE A 30 GLY A 9	None	0.81A	11gsA-2gupA: undetectable	11gsA-2gupA: 21.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1GRM_A_DVAA6_0 (GRAMICIDIN A)	2gup	ROK FAMILY PROTEIN (Streptococcus pneumoniae)	3 / 3	ALA A 204 VAL A 173 TRP A 185	None	0.94A	1grmA-2gupA: undetectable	1grmA-2gupA: 5.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1GRM_B_DVAB6_0 (GRAMICIDIN A)	2gup	ROK FAMILY PROTEIN (Streptococcus pneumoniae)	3 / 3	ALA A 204 VAL A 173 TRP A 185	None	0.94A	1grmB-2gupA: undetectable	1grmB-2gupA: 5.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1JO4_A_DVAA6_0 (GRAMICIDIN C)	2gup	ROK FAMILY PROTEIN (Streptococcus pneumoniae)	3 / 3	ALA A 204 VAL A 173 TRP A 185	None	0.91A	1jo4A-2gupA: undetectable	1jo4A-2gupA: 6.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1JO4_B_DVAB6_0 (GRAMICIDIN C)	2gup	ROK FAMILY PROTEIN (Streptococcus pneumoniae)	3 / 3	ALA A 204 VAL A 173 TRP A 185	None	0.91A	1jo4B-2gupA: undetectable	1jo4B-2gupA: 6.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1MAG_A_DVAA6_0 (GRAMICIDIN A)	2gup	ROK FAMILY PROTEIN (Streptococcus pneumoniae)	3 / 3	ALA A 204 VAL A 173 TRP A 185	None	0.96A	1magA-2gupA: undetectable	1magA-2gupA: 5.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1MAG_B_DVAB6_0 (GRAMICIDIN A)	2gup	ROK FAMILY PROTEIN (Streptococcus pneumoniae)	3 / 3	ALA A 204 VAL A 173 TRP A 185	None	0.96A	1magB-2gupA: undetectable	1magB-2gupA: 5.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1TD2_A_PXLA288_1 (PYRIDOXAMINE KINASE)	2gup	ROK FAMILY PROTEIN (Streptococcus pneumoniae)	5 / 10	SER A 107 VAL A 104 ALA A 273 HIS A 270 GLN A 236	None SUC A 290 (-4.7A) SUC A 290 ( 4.2A) SUC A 290 ( 3.9A) None	1.49A	1td2A-2gupA: undetectable	1td2A-2gupA: 21.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1X7P_A_SAMA301_0 (RRNA METHYLTRANSFERASE)	2gup	ROK FAMILY PROTEIN (Streptococcus pneumoniae)	6 / 11	GLU A 108 GLY A 231 ILE A 132 SER A 107 ALA A 101 ALA A 130	None SUC A 290 ( 4.5A) None None None None	1.36A	1x7pA-2gupA: undetectable 1x7pB-2gupA: undetectable	1x7pA-2gupA: 21.91 1x7pB-2gupA: 21.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2B60_B_RITB100_2 (GAG-POL POLYPROTEIN)	2gup	ROK FAMILY PROTEIN (Streptococcus pneumoniae)	5 / 11	ALA A 101 ASP A 100 GLY A 232 ILE A 123 ALA A 119	None TRS A 293 (-2.8A) SUC A 290 (-3.2A) None None	0.95A	2b60B-2gupA: undetectable	2b60B-2gupA: 18.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2B7Z_B_MK1B200_1 (HIV-1 PROTEASE)	2gup	ROK FAMILY PROTEIN (Streptococcus pneumoniae)	5 / 12	ALA A 101 ASP A 100 GLY A 232 ILE A 123 ALA A 119	None TRS A 293 (-2.8A) SUC A 290 (-3.2A) None None	0.99A	2b7zA-2gupA: undetectable	2b7zA-2gupA: 15.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2BJF_A_DXCA330_0 (CHOLOYLGLYCINE HYDROLASE)	2gup	ROK FAMILY PROTEIN (Streptococcus pneumoniae)	5 / 12	CYH A 103 ALA A 56 ASN A 274 ILE A 30 LEU A 275	None None SUC A 290 (-2.8A) None None	1.21A	2bjfA-2gupA: undetectable	2bjfA-2gupA: 21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2GSS_A_EAAA0_1 (GLUTATHIONE S-TRANSFERASE P1-1)	2gup	ROK FAMILY PROTEIN (Streptococcus pneumoniae)	4 / 8	TYR A 78 VAL A 76 ILE A 30 GLY A 9	None	0.84A	2gssA-2gupA: undetectable	2gssA-2gupA: 21.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2GSS_B_EAAB0_1 (GLUTATHIONE S-TRANSFERASE P1-1)	2gup	ROK FAMILY PROTEIN (Streptococcus pneumoniae)	4 / 8	TYR A 78 VAL A 76 ILE A 30 GLY A 9	None	0.85A	2gssB-2gupA: undetectable	2gssB-2gupA: 21.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3A51_E_VDYE6178_1 (VITAMIN D HYDROXYLASE)	2gup	ROK FAMILY PROTEIN (Streptococcus pneumoniae)	5 / 12	ILE A 264 ALA A 247 VAL A 252 PRO A 262 LEU A 217	None	1.18A	3a51E-2gupA: undetectable	3a51E-2gupA: 21.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3ADX_B_IMNB3_1 (PEROXISOME PROLIFERATOR-ACTIVAT ED RECEPTOR GAMMA)	2gup	ROK FAMILY PROTEIN (Streptococcus pneumoniae)	5 / 12	GLY A 231 ILE A 219 LEU A 216 VAL A 244 ILE A 241	SUC A 290 ( 4.5A) None None None None	0.97A	3adxB-2gupA: undetectable	3adxB-2gupA: 23.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3ADX_B_IMNB3_1 (PEROXISOME PROLIFERATOR-ACTIVAT ED RECEPTOR GAMMA)	2gup	ROK FAMILY PROTEIN (Streptococcus pneumoniae)	6 / 12	LEU A 43 GLY A 81 SER A 83 LEU A 97 VAL A 59 ILE A 79	None	1.21A	3adxB-2gupA: undetectable	3adxB-2gupA: 23.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3DOU_A_SAMA1_0 (RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE J)	2gup	ROK FAMILY PROTEIN (Streptococcus pneumoniae)	5 / 12	ALA A 266 SER A 233 GLY A 232 GLY A 231 ILE A 190	None SUC A 291 (-2.7A) SUC A 290 (-3.2A) SUC A 290 ( 4.5A) None	0.91A	3douA-2gupA: undetectable	3douA-2gupA: 18.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3G9E_A_RO7A1_1 (PEROXISOME PROLIFERATOR-ACTIVAT ED RECEPTOR GAMMA)	2gup	ROK FAMILY PROTEIN (Streptococcus pneumoniae)	5 / 12	GLY A 81 SER A 83 LEU A 97 VAL A 59 ILE A 79	None	1.18A	3g9eA-2gupA: undetectable	3g9eA-2gupA: 24.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3GSS_A_EAAA212_1 (GLUTATHIONE S-TRANSFERASE P1-1)	2gup	ROK FAMILY PROTEIN (Streptococcus pneumoniae)	4 / 7	TYR A 78 VAL A 76 ILE A 30 GLY A 9	None	0.82A	3gssA-2gupA: undetectable	3gssA-2gupA: 21.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3GSS_B_EAAB211_1 (GLUTATHIONE S-TRANSFERASE P1-1)	2gup	ROK FAMILY PROTEIN (Streptococcus pneumoniae)	4 / 7	TYR A 78 VAL A 76 ILE A 30 GLY A 9	None	0.82A	3gssB-2gupA: undetectable	3gssB-2gupA: 21.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3N9J_A_EAAA210_1 (GLUTATHIONE S-TRANSFERASE P)	2gup	ROK FAMILY PROTEIN (Streptococcus pneumoniae)	4 / 8	TYR A 78 VAL A 76 ILE A 30 GLY A 9	None	0.81A	3n9jA-2gupA: undetectable	3n9jA-2gupA: 21.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3OXC_A_ROCA401_3 (PROTEASE)	2gup	ROK FAMILY PROTEIN (Streptococcus pneumoniae)	5 / 12	LEU A 283 GLY A 277 ALA A 278 ILE A 6 ILE A 24	None	1.03A	3oxcB-2gupA: undetectable	3oxcB-2gupA: 15.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3OXV_B_478B200_2 (HIV-1 PROTEASE)	2gup	ROK FAMILY PROTEIN (Streptococcus pneumoniae)	5 / 10	ALA A 119 VAL A 227 GLY A 105 VAL A 104 ILE A 228	None None None SUC A 290 (-4.7A) None	1.08A	3oxvB-2gupA: undetectable	3oxvB-2gupA: 16.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3SO9_A_017A100_1 (HIV-1 PROTEASE)	2gup	ROK FAMILY PROTEIN (Streptococcus pneumoniae)	5 / 8	GLY A 129 ALA A 101 ASP A 100 GLY A 124 ILE A 123	None None TRS A 293 (-2.8A) None None	1.17A	3so9A-2gupA: undetectable	3so9A-2gupA: 16.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4JLT_A_8PRA505_1 (CYTOCHROME P450 2B4)	2gup	ROK FAMILY PROTEIN (Streptococcus pneumoniae)	4 / 8	ILE A 234 ILE A 190 ALA A 204 VAL A 244	None	0.76A	4jltA-2gupA: undetectable	4jltA-2gupA: 19.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4KOE_H_TR6H101_1 (DNA TOPOISOMERASE 4 SUBUNIT A DNA TOPOISOMERASE 4 SUBUNIT B E-SITE DNA4)	2gup	ROK FAMILY PROTEIN (Streptococcus pneumoniae)	4 / 7	SER A 235 ASP A 100 GLY A 129 GLU A 147	None TRS A 293 (-2.8A) None None	0.69A	4koeA-2gupA: undetectable 4koeB-2gupA: undetectable 4koeD-2gupA: 2.5	4koeA-2gupA: 20.76 4koeB-2gupA: 20.76 4koeD-2gupA: 18.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4OBW_C_SAMC601_0 (2-METHOXY-6-POLYPREN YL-1,4-BENZOQUINOL METHYLASE, MITOCHONDRIAL)	2gup	ROK FAMILY PROTEIN (Streptococcus pneumoniae)	5 / 12	GLY A 105 SER A 107 GLY A 146 SER A 229 PHE A 148	None	1.16A	4obwC-2gupA: undetectable	4obwC-2gupA: 21.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4OQR_A_2UOA502_1 (CYP105AS1)	2gup	ROK FAMILY PROTEIN (Streptococcus pneumoniae)	5 / 9	VAL A 104 ILE A 70 VAL A 63 ALA A 62 ALA A 101	SUC A 290 (-4.7A) None None None None	1.14A	4oqrA-2gupA: undetectable	4oqrA-2gupA: 20.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4XUM_B_IMNB501_1 (PEROXISOME PROLIFERATOR-ACTIVAT ED RECEPTOR GAMMA)	2gup	ROK FAMILY PROTEIN (Streptococcus pneumoniae)	5 / 11	GLY A 231 ALA A 119 ILE A 219 LEU A 216 ILE A 241	SUC A 290 ( 4.5A) None None None None	1.15A	4xumB-2gupA: undetectable	4xumB-2gupA: 24.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4Z53_H_TR6H101_1 (DNA TOPOISOMERASE 4 SUBUNIT B,DNA TOPOISOMERASE 4 SUBUNIT A E-SITE DNA)	2gup	ROK FAMILY PROTEIN (Streptococcus pneumoniae)	4 / 7	ASP A 100 GLY A 129 GLU A 147 SER A 235	TRS A 293 (-2.8A) None None None	0.69A	4z53A-2gupA: undetectable 4z53B-2gupA: undetectable	4z53A-2gupA: 17.98 4z53B-2gupA: 17.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5CDQ_F_MFXF2101_1 (DNA GYRASE SUBUNIT A DNA GYRASE SUBUNIT B,DNA GYRASE SUBUNIT B)	2gup	ROK FAMILY PROTEIN (Streptococcus pneumoniae)	4 / 6	SER A 235 ASP A 100 GLY A 129 GLU A 147	None TRS A 293 (-2.8A) None None	0.92A	5cdqA-2gupA: undetectable 5cdqC-2gupA: undetectable 5cdqD-2gupA: undetectable	5cdqA-2gupA: 21.69 5cdqC-2gupA: 21.69 5cdqD-2gupA: 24.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5FPD_B_PZAB1385_0 (HEAT SHOCK-RELATED 70KDA PROTEIN 2)	2gup	ROK FAMILY PROTEIN (Streptococcus pneumoniae)	4 / 7	ASN A 274 VAL A 104 GLY A 128 VAL A 122	SUC A 290 (-2.8A) SUC A 290 (-4.7A) None None	0.80A	5fpdB-2gupA: 10.6	5fpdB-2gupA: 22.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5HI2_A_BAXA801_2 (SERINE/THREONINE-PRO TEIN KINASE B-RAF)	2gup	ROK FAMILY PROTEIN (Streptococcus pneumoniae)	5 / 8	ILE A 177 VAL A 176 VAL A 244 ILE A 123 ILE A 127	None	1.39A	5hi2A-2gupA: undetectable	5hi2A-2gupA: 21.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5MUE_A_VIVA302_0 (ALPHA-TOCOPHEROL TRANSFER PROTEIN)	2gup	ROK FAMILY PROTEIN (Streptococcus pneumoniae)	5 / 12	ILE A 8 PHE A 82 LEU A 97 VAL A 59 ILE A 70	None	0.99A	5mueA-2gupA: undetectable	5mueA-2gupA: 19.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5YCN_A_8LXA501_0 (PEROXISOME PROLIFERATOR-ACTIVAT ED RECEPTOR GAMMA)	2gup	ROK FAMILY PROTEIN (Streptococcus pneumoniae)	5 / 12	ILE A 234 GLY A 231 LEU A 216 VAL A 244 ILE A 241	None SUC A 290 ( 4.5A) None None None	1.03A	5ycnA-2gupA: undetectable	5ycnA-2gupA: 23.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5ZGB_B_PQNB844_1 (PSAB)	2gup	ROK FAMILY PROTEIN (Streptococcus pneumoniae)	5 / 9	ILE A 241 MET A 151 ALA A 213 LEU A 212 ALA A 167	None	1.21A	5zgbB-2gupA: undetectable	5zgbB-2gupA: 15.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6DWN_B_AQ4B602_1 (CYTOCHROME P450 1A1)	2gup	ROK FAMILY PROTEIN (Streptococcus pneumoniae)	4 / 7	SER A 74 ASN A 102 VAL A 95 LEU A 97	None None SUC A 292 (-4.1A) None	0.80A	6dwnB-2gupA: undetectable	6dwnB-2gupA: 12.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6GIQ_I_PCFI101_0 (CYTOCHROME B-C1 COMPLEX SUBUNIT 1, MITOCHONDRIAL CYTOCHROME B-C1 COMPLEX SUBUNIT 9 CYTOCHROME B-C1 COMPLEX SUBUNIT RIESKE, MITOCHONDRIAL)	2gup	ROK FAMILY PROTEIN (Streptococcus pneumoniae)	5 / 9	ASP A 7 SER A 58 GLY A 126 SER A 164 ASN A 99	SUC A 290 (-3.5A) None None None TRS A 293 (-3.9A)	1.47A	6giqA-2gupA: 0.0 6giqE-2gupA: 0.0 6giqI-2gupA: 0.0	6giqA-2gupA: 23.64 6giqE-2gupA: 21.68 6giqI-2gupA: 13.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6HU9_H_PCFH604_0 (CYTOCHROME B-C1 COMPLEX SUBUNIT 8 CYTOCHROME C OXIDASE POLYPEPTIDE 5A, MITOCHONDRIAL)	2gup	ROK FAMILY PROTEIN (Streptococcus pneumoniae)	5 / 8	GLY A 231 HIS A 270 GLY A 277 SER A 107 ALA A 111	SUC A 290 ( 4.5A) SUC A 290 ( 3.9A) None None None	1.21A	6hu9H-2gupA: undetectable 6hu9e-2gupA: undetectable	6hu9H-2gupA: 16.44 6hu9e-2gupA: 17.93

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["11GS_A_EAAA211_1","GLUTATHIONE S-TRANSFERASE","2gup","ROK FAMILY PROTEIN","Streptococcus pneumoniae",4,"TYR A  78;VAL A  76;ILE A  30;GLY A   9","None","0.81A","11gsA-2gupA:undetectable","11gsA-2gupA:21.48"],["1GRM_A_DVAA6_0","GRAMICIDIN A","2gup","ROK FAMILY PROTEIN","Streptococcus pneumoniae",3,"ALA A 204;VAL A 173;TRP A 185","None","0.94A","1grmA-2gupA:undetectable","1grmA-2gupA:5.29"],["1GRM_B_DVAB6_0","GRAMICIDIN A","2gup","ROK FAMILY PROTEIN","Streptococcus pneumoniae",3,"ALA A 204;VAL A 173;TRP A 185","None","0.94A","1grmB-2gupA:undetectable","1grmB-2gupA:5.29"],["1JO4_A_DVAA6_0","GRAMICIDIN C","2gup","ROK FAMILY PROTEIN","Streptococcus pneumoniae",3,"ALA A 204;VAL A 173;TRP A 185","None","0.91A","1jo4A-2gupA:undetectable","1jo4A-2gupA:6.17"],["1JO4_B_DVAB6_0","GRAMICIDIN C","2gup","ROK FAMILY PROTEIN","Streptococcus pneumoniae",3,"ALA A 204;VAL A 173;TRP A 185","None","0.91A","1jo4B-2gupA:undetectable","1jo4B-2gupA:6.17"],["1MAG_A_DVAA6_0","GRAMICIDIN A","2gup","ROK FAMILY PROTEIN","Streptococcus pneumoniae",3,"ALA A 204;VAL A 173;TRP A 185","None","0.96A","1magA-2gupA:undetectable","1magA-2gupA:5.29"],["1MAG_B_DVAB6_0","GRAMICIDIN A","2gup","ROK FAMILY PROTEIN","Streptococcus pneumoniae",3,"ALA A 204;VAL A 173;TRP A 185","None","0.96A","1magB-2gupA:undetectable","1magB-2gupA:5.29"],["1TD2_A_PXLA288_1","PYRIDOXAMINE KINASE","2gup","ROK FAMILY PROTEIN","Streptococcus pneumoniae",5,"SER A 107;VAL A 104;ALA A 273;HIS A 270;GLN A 236","None;SUC A 290 (-4.7A);SUC A 290 ( 4.2A);SUC A 290 ( 3.9A);None","1.49A","1td2A-2gupA:undetectable","1td2A-2gupA:21.49"],["1X7P_A_SAMA301_0","RRNA METHYLTRANSFERASE","2gup","ROK FAMILY PROTEIN","Streptococcus pneumoniae",6,"GLU A 108;GLY A 231;ILE A 132;SER A 107;ALA A 101;ALA A 130","None;SUC A 290 ( 4.5A);None;None;None;None","1.36A","1x7pA-2gupA:undetectable;1x7pB-2gupA:undetectable","1x7pA-2gupA:21.91;1x7pB-2gupA:21.91"],["2B60_B_RITB100_2","GAG-POL POLYPROTEIN","2gup","ROK FAMILY PROTEIN","Streptococcus pneumoniae",5,"ALA A 101;ASP A 100;GLY A 232;ILE A 123;ALA A 119","None;TRS A 293 (-2.8A);SUC A 290 (-3.2A);None;None","0.95A","2b60B-2gupA:undetectable","2b60B-2gupA:18.33"],["2B7Z_B_MK1B200_1","HIV-1 PROTEASE;HIV-1 PROTEASE","2gup","ROK FAMILY PROTEIN","Streptococcus pneumoniae",5,"ALA A 101;ASP A 100;GLY A 232;ILE A 123;ALA A 119","None;TRS A 293 (-2.8A);SUC A 290 (-3.2A);None;None","0.99A","2b7zA-2gupA:undetectable","2b7zA-2gupA:15.41"],["2BJF_A_DXCA330_0","CHOLOYLGLYCINE HYDROLASE","2gup","ROK FAMILY PROTEIN","Streptococcus pneumoniae",5,"CYH A 103;ALA A  56;ASN A 274;ILE A  30;LEU A 275","None;None;SUC A 290 (-2.8A);None;None","1.21A","2bjfA-2gupA:undetectable","2bjfA-2gupA:21.88"],["2GSS_A_EAAA0_1","GLUTATHIONE S-TRANSFERASE P1-1","2gup","ROK FAMILY PROTEIN","Streptococcus pneumoniae",4,"TYR A  78;VAL A  76;ILE A  30;GLY A   9","None","0.84A","2gssA-2gupA:undetectable","2gssA-2gupA:21.48"],["2GSS_B_EAAB0_1","GLUTATHIONE S-TRANSFERASE P1-1","2gup","ROK FAMILY PROTEIN","Streptococcus pneumoniae",4,"TYR A  78;VAL A  76;ILE A  30;GLY A   9","None","0.85A","2gssB-2gupA:undetectable","2gssB-2gupA:21.48"],["3A51_E_VDYE6178_1","VITAMIN D HYDROXYLASE","2gup","ROK FAMILY PROTEIN","Streptococcus pneumoniae",5,"ILE A 264;ALA A 247;VAL A 252;PRO A 262;LEU A 217","None","1.18A","3a51E-2gupA:undetectable","3a51E-2gupA:21.21"],["3ADX_B_IMNB3_1","PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR GAMMA","2gup","ROK FAMILY PROTEIN","Streptococcus pneumoniae",5,"GLY A 231;ILE A 219;LEU A 216;VAL A 244;ILE A 241","SUC A 290 ( 4.5A);None;None;None;None","0.97A","3adxB-2gupA:undetectable","3adxB-2gupA:23.87"],["3ADX_B_IMNB3_1","PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR GAMMA","2gup","ROK FAMILY PROTEIN","Streptococcus pneumoniae",6,"LEU A  43;GLY A  81;SER A  83;LEU A  97;VAL A  59;ILE A  79","None","1.21A","3adxB-2gupA:undetectable","3adxB-2gupA:23.87"],["3DOU_A_SAMA1_0","RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE J","2gup","ROK FAMILY PROTEIN","Streptococcus pneumoniae",5,"ALA A 266;SER A 233;GLY A 232;GLY A 231;ILE A 190","None;SUC A 291 (-2.7A);SUC A 290 (-3.2A);SUC A 290 ( 4.5A);None","0.91A","3douA-2gupA:undetectable","3douA-2gupA:18.97"],["3G9E_A_RO7A1_1","PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR GAMMA","2gup","ROK FAMILY PROTEIN","Streptococcus pneumoniae",5,"GLY A  81;SER A  83;LEU A  97;VAL A  59;ILE A  79","None","1.18A","3g9eA-2gupA:undetectable","3g9eA-2gupA:24.37"],["3GSS_A_EAAA212_1","GLUTATHIONE S-TRANSFERASE P1-1","2gup","ROK FAMILY PROTEIN","Streptococcus pneumoniae",4,"TYR A  78;VAL A  76;ILE A  30;GLY A   9","None","0.82A","3gssA-2gupA:undetectable","3gssA-2gupA:21.48"],["3GSS_B_EAAB211_1","GLUTATHIONE S-TRANSFERASE P1-1","2gup","ROK FAMILY PROTEIN","Streptococcus pneumoniae",4,"TYR A  78;VAL A  76;ILE A  30;GLY A   9","None","0.82A","3gssB-2gupA:undetectable","3gssB-2gupA:21.48"],["3N9J_A_EAAA210_1","GLUTATHIONE S-TRANSFERASE P","2gup","ROK FAMILY PROTEIN","Streptococcus pneumoniae",4,"TYR A  78;VAL A  76;ILE A  30;GLY A   9","None","0.81A","3n9jA-2gupA:undetectable","3n9jA-2gupA:21.48"],["3OXC_A_ROCA401_3","PROTEASE;PROTEASE","2gup","ROK FAMILY PROTEIN","Streptococcus pneumoniae",5,"LEU A 283;GLY A 277;ALA A 278;ILE A   6;ILE A  24","None","1.03A","3oxcB-2gupA:undetectable","3oxcB-2gupA:15.86"],["3OXV_B_478B200_2","HIV-1 PROTEASE","2gup","ROK FAMILY PROTEIN","Streptococcus pneumoniae",5,"ALA A 119;VAL A 227;GLY A 105;VAL A 104;ILE A 228","None;None;None;SUC A 290 (-4.7A);None","1.08A","3oxvB-2gupA:undetectable","3oxvB-2gupA:16.55"],["3SO9_A_017A100_1","HIV-1 PROTEASE","2gup","ROK FAMILY PROTEIN","Streptococcus pneumoniae",5,"GLY A 129;ALA A 101;ASP A 100;GLY A 124;ILE A 123","None;None;TRS A 293 (-2.8A);None;None","1.17A","3so9A-2gupA:undetectable","3so9A-2gupA:16.44"],["4JLT_A_8PRA505_1","CYTOCHROME P450 2B4","2gup","ROK FAMILY PROTEIN","Streptococcus pneumoniae",4,"ILE A 234;ILE A 190;ALA A 204;VAL A 244","None","0.76A","4jltA-2gupA:undetectable","4jltA-2gupA:19.11"],["4KOE_H_TR6H101_1","DNA TOPOISOMERASE 4 SUBUNIT A;DNA TOPOISOMERASE 4 SUBUNIT A;DNA TOPOISOMERASE 4 SUBUNIT B;E-SITE DNA4","2gup","ROK FAMILY PROTEIN","Streptococcus pneumoniae",4,"SER A 235;ASP A 100;GLY A 129;GLU A 147","None;TRS A 293 (-2.8A);None;None","0.69A","4koeA-2gupA:undetectable;4koeB-2gupA:undetectable;4koeD-2gupA:2.5","4koeA-2gupA:20.76;4koeB-2gupA:20.76;4koeD-2gupA:18.24"],["4OBW_C_SAMC601_0","2-METHOXY-6-POLYPRENYL-1,4-BENZOQUINOL METHYLASE, MITOCHONDRIAL","2gup","ROK FAMILY PROTEIN","Streptococcus pneumoniae",5,"GLY A 105;SER A 107;GLY A 146;SER A 229;PHE A 148","None","1.16A","4obwC-2gupA:undetectable","4obwC-2gupA:21.52"],["4OQR_A_2UOA502_1","CYP105AS1","2gup","ROK FAMILY PROTEIN","Streptococcus pneumoniae",5,"VAL A 104;ILE A  70;VAL A  63;ALA A  62;ALA A 101","SUC A 290 (-4.7A);None;None;None;None","1.14A","4oqrA-2gupA:undetectable","4oqrA-2gupA:20.17"],["4XUM_B_IMNB501_1","PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR GAMMA","2gup","ROK FAMILY PROTEIN","Streptococcus pneumoniae",5,"GLY A 231;ALA A 119;ILE A 219;LEU A 216;ILE A 241","SUC A 290 ( 4.5A);None;None;None;None","1.15A","4xumB-2gupA:undetectable","4xumB-2gupA:24.53"],["4Z53_H_TR6H101_1","DNA TOPOISOMERASE 4 SUBUNIT B,DNA TOPOISOMERASE 4 SUBUNIT A;DNA TOPOISOMERASE 4 SUBUNIT B,DNA TOPOISOMERASE 4 SUBUNIT A;E-SITE DNA","2gup","ROK FAMILY PROTEIN","Streptococcus pneumoniae",4,"ASP A 100;GLY A 129;GLU A 147;SER A 235","TRS A 293 (-2.8A);None;None;None","0.69A","4z53A-2gupA:undetectable;4z53B-2gupA:undetectable","4z53A-2gupA:17.98;4z53B-2gupA:17.98"],["5CDQ_F_MFXF2101_1","DNA GYRASE SUBUNIT A;DNA GYRASE SUBUNIT A;DNA GYRASE SUBUNIT B,DNA GYRASE SUBUNIT B","2gup","ROK FAMILY PROTEIN","Streptococcus pneumoniae",4,"SER A 235;ASP A 100;GLY A 129;GLU A 147","None;TRS A 293 (-2.8A);None;None","0.92A","5cdqA-2gupA:undetectable;5cdqC-2gupA:undetectable;5cdqD-2gupA:undetectable","5cdqA-2gupA:21.69;5cdqC-2gupA:21.69;5cdqD-2gupA:24.13"],["5FPD_B_PZAB1385_0","HEAT SHOCK-RELATED 70KDA PROTEIN 2","2gup","ROK FAMILY PROTEIN","Streptococcus pneumoniae",4,"ASN A 274;VAL A 104;GLY A 128;VAL A 122","SUC A 290 (-2.8A);SUC A 290 (-4.7A);None;None","0.80A","5fpdB-2gupA:10.6","5fpdB-2gupA:22.39"],["5HI2_A_BAXA801_2","SERINE\/THREONINE-PROTEIN KINASE B-RAF","2gup","ROK FAMILY PROTEIN","Streptococcus pneumoniae",5,"ILE A 177;VAL A 176;VAL A 244;ILE A 123;ILE A 127","None","1.39A","5hi2A-2gupA:undetectable","5hi2A-2gupA:21.81"],["5MUE_A_VIVA302_0","ALPHA-TOCOPHEROL TRANSFER PROTEIN","2gup","ROK FAMILY PROTEIN","Streptococcus pneumoniae",5,"ILE A   8;PHE A  82;LEU A  97;VAL A  59;ILE A  70","None","0.99A","5mueA-2gupA:undetectable","5mueA-2gupA:19.40"],["5YCN_A_8LXA501_0","PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR GAMMA","2gup","ROK FAMILY PROTEIN","Streptococcus pneumoniae",5,"ILE A 234;GLY A 231;LEU A 216;VAL A 244;ILE A 241","None;SUC A 290 ( 4.5A);None;None;None","1.03A","5ycnA-2gupA:undetectable","5ycnA-2gupA:23.78"],["5ZGB_B_PQNB844_1","PSAB","2gup","ROK FAMILY PROTEIN","Streptococcus pneumoniae",5,"ILE A 241;MET A 151;ALA A 213;LEU A 212;ALA A 167","None","1.21A","5zgbB-2gupA:undetectable","5zgbB-2gupA:15.33"],["6DWN_B_AQ4B602_1","CYTOCHROME P450 1A1","2gup","ROK FAMILY PROTEIN","Streptococcus pneumoniae",4,"SER A  74;ASN A 102;VAL A  95;LEU A  97","None;None;SUC A 292 (-4.1A);None","0.80A","6dwnB-2gupA:undetectable","6dwnB-2gupA:12.46"],["6GIQ_I_PCFI101_0","CYTOCHROME B-C1 COMPLEX SUBUNIT 1, MITOCHONDRIAL;CYTOCHROME B-C1 COMPLEX SUBUNIT 9;CYTOCHROME B-C1 COMPLEX SUBUNIT RIESKE, MITOCHONDRIAL","2gup","ROK FAMILY PROTEIN","Streptococcus pneumoniae",5,"ASP A   7;SER A  58;GLY A 126;SER A 164;ASN A  99","SUC A 290 (-3.5A);None;None;None;TRS A 293 (-3.9A)","1.47A","6giqA-2gupA:0.0;6giqE-2gupA:0.0;6giqI-2gupA:0.0","6giqA-2gupA:23.64;6giqE-2gupA:21.68;6giqI-2gupA:13.67"],["6HU9_H_PCFH604_0","CYTOCHROME B-C1 COMPLEX SUBUNIT 8;CYTOCHROME C OXIDASE POLYPEPTIDE 5A, MITOCHONDRIAL","2gup","ROK FAMILY PROTEIN","Streptococcus pneumoniae",5,"GLY A 231;HIS A 270;GLY A 277;SER A 107;ALA A 111","SUC A 290 ( 4.5A);SUC A 290 ( 3.9A);None;None;None","1.21A","6hu9H-2gupA:undetectable;6hu9e-2gupA:undetectable","6hu9H-2gupA:16.44;6hu9e-2gupA:17.93"]]