SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2gux'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F8D_B_BEZB1003_0
(HTH-TYPE
TRANSCRIPTIONAL
REGULATOR BENM)		 2gux GRIFFITHSIN
(Griffithsia) 		5 / 10 GLY A 105
LEU A 114
ILE A 116
LEU A  18
ILE A  34
 None
 1.04A 2f8dB-2guxA:
undetectable		 2f8dB-2guxA:
20.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VAQ_A_ADNA401_1
(PUTATIVE ADENOSINE
KINASE)		 2gux GRIFFITHSIN
(Griffithsia) 		5 / 12 ILE A  63
LEU A 114
GLY A  87
GLY A  86
LEU A 111
 None
 0.93A 3vaqA-2guxA:
undetectable		 3vaqA-2guxA:
20.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4B53_B_ACTB1445_0
(IG GAMMA-4 CHAIN C
REGION)		 2gux GRIFFITHSIN
(Griffithsia) 		3 / 3 GLU A  75
GLY A  79
SER A  59
 None
 0.50A 4b53B-2guxA:
undetectable		 4b53B-2guxA:
20.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L8F_B_MTXB301_1
(GAMMA-GLUTAMYL
HYDROLASE)		 2gux GRIFFITHSIN
(Griffithsia) 		5 / 11 GLY A  41
GLY A  43
GLY A  44
ALA A  31
HIS A  38
 None
 1.04A 4l8fB-2guxA:
undetectable		 4l8fB-2guxA:
18.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L8F_D_MTXD301_1
(GAMMA-GLUTAMYL
HYDROLASE)		 2gux GRIFFITHSIN
(Griffithsia) 		5 / 11 GLY A  41
GLY A  43
GLY A  44
ALA A  31
HIS A  38
 None
 1.04A 4l8fD-2guxA:
undetectable		 4l8fD-2guxA:
18.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6J20_A_GBQA1201_0
(SUBSTANCE-P
RECEPTOR,ENDOLYSIN)		 2gux GRIFFITHSIN
(Griffithsia) 		5 / 12 VAL A 100
ILE A  33
ILE A 116
PHE A  74
PHE A  82
 None
 1.37A 6j20A-2guxA:
undetectable		 6j20A-2guxA:
14.44