SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2gv0'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KYV_B_RBFB502_1
(6,7-DIMETHYL-8-RIBIT
YLLUMAZINE SYNTHASE)		 2gv0 LYSOZYME C
(Pelodiscus
sinensis) 		5 / 11 HIS A  35
TRP A 125
GLY A  27
TRP A  29
LEU A   9
 None
 1.44A 1kyvA-2gv0A:
undetectable
1kyvB-2gv0A:
undetectable		 1kyvA-2gv0A:
21.69
1kyvB-2gv0A:
21.69
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1N4F_A_ASRA141_0
(LYSOZYME C)		 2gv0 LYSOZYME C
(Pelodiscus
sinensis) 		4 / 6 ASN A  67
ASP A  68
GLY A  69
THR A  71
 None
 0.21A 1n4fA-2gv0A:
25.9		 1n4fA-2gv0A:
68.46
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1N4F_A_ASRA141_0
(LYSOZYME C)		 2gv0 LYSOZYME C
(Pelodiscus
sinensis) 		4 / 6 ASN A  67
ASP A  68
THR A  71
PRO A  72
 None
 0.99A 1n4fA-2gv0A:
25.9		 1n4fA-2gv0A:
68.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P6K_A_MTLA870_0
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 2gv0 LYSOZYME C
(Pelodiscus
sinensis) 		4 / 8 SER A  62
GLN A  51
ASN A  61
ASP A  50
 None
 1.17A 1p6kA-2gv0A:
undetectable		 1p6kA-2gv0A:
15.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P6K_B_MTLB871_0
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 2gv0 LYSOZYME C
(Pelodiscus
sinensis) 		4 / 8 SER A  62
GLN A  51
ASN A  61
ASP A  50
 None
 1.19A 1p6kB-2gv0A:
undetectable		 1p6kB-2gv0A:
15.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RS6_A_MTLA870_0
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 2gv0 LYSOZYME C
(Pelodiscus
sinensis) 		4 / 8 SER A  62
GLN A  51
ASN A  61
ASP A  50
 None
 1.14A 1rs6A-2gv0A:
undetectable		 1rs6A-2gv0A:
15.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RS6_B_MTLB871_0
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 2gv0 LYSOZYME C
(Pelodiscus
sinensis) 		4 / 8 SER A  62
GLN A  51
ASN A  61
ASP A  50
 None
 1.16A 1rs6B-2gv0A:
undetectable		 1rs6B-2gv0A:
15.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RS7_B_MTLB871_0
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 2gv0 LYSOZYME C
(Pelodiscus
sinensis) 		4 / 8 SER A  62
GLN A  51
ASN A  61
ASP A  50
 None
 1.21A 1rs7B-2gv0A:
undetectable		 1rs7B-2gv0A:
15.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZZQ_A_MTLA870_0
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 2gv0 LYSOZYME C
(Pelodiscus
sinensis) 		4 / 8 SER A  62
GLN A  51
ASN A  61
ASP A  50
 None
 1.15A 1zzqA-2gv0A:
undetectable		 1zzqA-2gv0A:
14.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZZQ_B_MTLB871_0
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 2gv0 LYSOZYME C
(Pelodiscus
sinensis) 		4 / 8 SER A  62
GLN A  51
ASN A  61
ASP A  50
 None
 1.16A 1zzqB-2gv0A:
undetectable		 1zzqB-2gv0A:
14.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZZU_B_MTLB871_0
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 2gv0 LYSOZYME C
(Pelodiscus
sinensis) 		4 / 8 SER A  62
GLN A  51
ASN A  61
ASP A  50
 None
 1.19A 1zzuB-2gv0A:
undetectable		 1zzuB-2gv0A:
14.76
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4AGA_A_ACTA1131_0
(LYSOZYME C)		 2gv0 LYSOZYME C
(Pelodiscus
sinensis) 		3 / 3 ASN A  47
ASP A  54
ASN A  61
 None
 0.34A 4agaA-2gv0A:
25.6		 4agaA-2gv0A:
68.46
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4II8_A_010A210_0
(LYSOZYME C)		 2gv0 LYSOZYME C
(Pelodiscus
sinensis) 		7 / 7 GLU A  36
ASP A  54
GLN A  59
ASN A  61
TRP A  65
ILE A 100
TRP A 110
 None
 0.28A 4ii8A-2gv0A:
25.7		 4ii8A-2gv0A:
68.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCN_B_MTLB806_0
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2gv0 LYSOZYME C
(Pelodiscus
sinensis) 		4 / 7 SER A  62
GLN A  51
ASN A  61
ASP A  50
 None
 1.25A 4kcnB-2gv0A:
undetectable		 4kcnB-2gv0A:
14.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V1F_B_BQ1B1087_0
(F0F1 ATP SYNTHASE
SUBUNIT C)		 2gv0 LYSOZYME C
(Pelodiscus
sinensis) 		5 / 8 ALA A  88
ILE A  90
TYR A   4
PHE A  39
LEU A   9
 None
 1.10A 4v1fA-2gv0A:
undetectable
4v1fB-2gv0A:
undetectable		 4v1fA-2gv0A:
17.60
4v1fB-2gv0A:
17.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V1F_B_BQ1B1087_0
(F0F1 ATP SYNTHASE
SUBUNIT C)		 2gv0 LYSOZYME C
(Pelodiscus
sinensis) 		5 / 8 ALA A  88
ILE A  90
TYR A   4
PHE A  39
LEU A   9
 None
 1.46A 4v1fA-2gv0A:
undetectable
4v1fB-2gv0A:
undetectable		 4v1fA-2gv0A:
17.60
4v1fB-2gv0A:
17.60
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5DL9_A_ACTA214_0
(LYSOZYME C)		 2gv0 LYSOZYME C
(Pelodiscus
sinensis) 		5 / 5 GLU A  36
ASP A  54
TRP A 110
VAL A 111
ALA A 112
 None
 0.54A 5dl9A-2gv0A:
25.5		 5dl9A-2gv0A:
68.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUN_A_MTLA805_0
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2gv0 LYSOZYME C
(Pelodiscus
sinensis) 		4 / 8 SER A  62
GLN A  51
ASN A  61
ASP A  50
 None
 1.23A 5vunA-2gv0A:
undetectable		 5vunA-2gv0A:
14.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUN_B_MTLB805_0
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2gv0 LYSOZYME C
(Pelodiscus
sinensis) 		4 / 8 SER A  62
GLN A  51
ASN A  61
ASP A  50
 None
 1.23A 5vunB-2gv0A:
undetectable		 5vunB-2gv0A:
14.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUO_B_MTLB805_0
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2gv0 LYSOZYME C
(Pelodiscus
sinensis) 		4 / 8 SER A  62
GLN A  51
ASN A  61
ASP A  50
 None
 1.21A 5vuoB-2gv0A:
undetectable		 5vuoB-2gv0A:
14.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VW9_A_NCAA403_0
(FERREDOXIN--NADP
REDUCTASE)		 2gv0 LYSOZYME C
(Pelodiscus
sinensis) 		5 / 8 SER A  37
THR A  41
GLY A  56
ALA A  43
GLU A  36
 None
 1.18A 5vw9A-2gv0A:
undetectable		 5vw9A-2gv0A:
17.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUU_B_MTLB805_0
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2gv0 LYSOZYME C
(Pelodiscus
sinensis) 		4 / 8 SER A  62
GLN A  51
ASN A  61
ASP A  50
 None
 1.21A 6auuB-2gv0A:
undetectable		 6auuB-2gv0A:
14.69