SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2gv8'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FM4_A_DXCA1002_0
(MAJOR POLLEN
ALLERGEN BET V 1-L)		 2gv8 MONOOXYGENASE
(Schizosaccharomy
ces
pombe) 		5 / 12 VAL A 316
ILE A 171
VAL A 138
SER A 298
LEU A 309
 None
None
FAD  A 500 (-4.0A)
None
None
 1.18A 1fm4A-2gv8A:
undetectable		 1fm4A-2gv8A:
19.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1USQ_F_CLMF1144_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 2gv8 MONOOXYGENASE
(Schizosaccharomy
ces
pombe) 		4 / 7 PRO A  43
GLY A  15
ILE A  11
GLY A  13
 None
FAD  A 500 (-3.4A)
None
FAD  A 500 (-3.1A)
 0.85A 1usqF-2gv8A:
undetectable		 1usqF-2gv8A:
14.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YMX_A_CFXA1001_2
(BETA-LACTAMASE
CTX-M-9)		 2gv8 MONOOXYGENASE
(Schizosaccharomy
ces
pombe) 		4 / 5 CYH A 287
TYR A 176
PRO A 179
SER A 223
 None
NDP  A 501 ( 3.8A)
None
NDP  A 501 (-2.8A)
 1.33A 1ymxA-2gv8A:
undetectable		 1ymxA-2gv8A:
20.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z9H_A_IMNA379_1
(MEMBRANE-ASSOCIATED
PROSTAGLANDIN E
SYNTHASE-2)		 2gv8 MONOOXYGENASE
(Schizosaccharomy
ces
pombe) 		6 / 12 THR A 288
CYH A 287
SER A  61
TYR A 180
ILE A 181
LEU A 291
 NDP  A 501 (-4.2A)
None
None
None
None
None
 1.31A 1z9hA-2gv8A:
undetectable		 1z9hA-2gv8A:
22.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z9H_B_IMNB381_1
(MEMBRANE-ASSOCIATED
PROSTAGLANDIN E
SYNTHASE-2)		 2gv8 MONOOXYGENASE
(Schizosaccharomy
ces
pombe) 		6 / 12 THR A 288
CYH A 287
SER A  61
TYR A 180
ILE A 181
LEU A 291
 NDP  A 501 (-4.2A)
None
None
None
None
None
 1.31A 1z9hB-2gv8A:
undetectable		 1z9hB-2gv8A:
22.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z9H_C_IMNC379_1
(MEMBRANE-ASSOCIATED
PROSTAGLANDIN E
SYNTHASE-2)		 2gv8 MONOOXYGENASE
(Schizosaccharomy
ces
pombe) 		5 / 12 THR A 288
CYH A 287
SER A  61
ILE A 181
LEU A 291
 NDP  A 501 (-4.2A)
None
None
None
None
 0.98A 1z9hC-2gv8A:
undetectable		 1z9hC-2gv8A:
22.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z9H_C_IMNC379_1
(MEMBRANE-ASSOCIATED
PROSTAGLANDIN E
SYNTHASE-2)		 2gv8 MONOOXYGENASE
(Schizosaccharomy
ces
pombe) 		5 / 12 THR A 288
SER A  61
TYR A 180
ILE A 181
LEU A 291
 NDP  A 501 (-4.2A)
None
None
None
None
 1.37A 1z9hC-2gv8A:
undetectable		 1z9hC-2gv8A:
22.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z9H_D_IMND476_1
(MEMBRANE-ASSOCIATED
PROSTAGLANDIN E
SYNTHASE-2)		 2gv8 MONOOXYGENASE
(Schizosaccharomy
ces
pombe) 		6 / 12 THR A 288
CYH A 287
SER A  61
TYR A 180
ILE A 181
LEU A 291
 NDP  A 501 (-4.2A)
None
None
None
None
None
 1.31A 1z9hD-2gv8A:
undetectable		 1z9hD-2gv8A:
22.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZGY_A_BRLA503_1
(PEROXISOME
PROLIFERATOR
ACTIVATED RECEPTOR
GAMMA)		 2gv8 MONOOXYGENASE
(Schizosaccharomy
ces
pombe) 		5 / 12 GLY A 220
SER A 223
TYR A 290
HIS A 200
LEU A 227
 NDP  A 501 ( 4.2A)
NDP  A 501 (-2.8A)
None
None
None
 1.47A 1zgyA-2gv8A:
undetectable		 1zgyA-2gv8A:
21.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXG_A_IBPA2002_1
(SERUM ALBUMIN)		 2gv8 MONOOXYGENASE
(Schizosaccharomy
ces
pombe) 		4 / 8 ARG A 360
ALA A 354
GLU A 416
LEU A  26
 None
 0.90A 2bxgA-2gv8A:
undetectable		 2bxgA-2gv8A:
22.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F6D_A_ACRA996_1
(GLUCOAMYLASE GLU1)		 2gv8 MONOOXYGENASE
(Schizosaccharomy
ces
pombe) 		4 / 7 ASP A 312
THR A 288
GLY A 289
TYR A 180
 None
NDP  A 501 (-4.2A)
NDP  A 501 ( 3.7A)
None
 0.95A 2f6dA-2gv8A:
undetectable		 2f6dA-2gv8A:
22.52
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2GVC_B_MMZB501_1
(MONOOXYGENASE)		 2gv8 MONOOXYGENASE
(Schizosaccharomy
ces
pombe) 		3 / 3 ASN A  91
TYR A 176
SER A 223
 NDP  A 501 ( 3.5A)
NDP  A 501 ( 3.8A)
NDP  A 501 (-2.8A)
 0.65A 2gvcB-2gv8A:
65.0		 2gvcB-2gv8A:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2GVC_E_MMZE501_1
(MONOOXYGENASE)		 2gv8 MONOOXYGENASE
(Schizosaccharomy
ces
pombe) 		3 / 3 ASN A  91
TYR A 176
SER A 223
 NDP  A 501 ( 3.5A)
NDP  A 501 ( 3.8A)
NDP  A 501 (-2.8A)
 0.65A 2gvcE-2gv8A:
65.1		 2gvcE-2gv8A:
100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HJH_B_NCAB901_0
(NAD-DEPENDENT
HISTONE DEACETYLASE
SIR2)		 2gv8 MONOOXYGENASE
(Schizosaccharomy
ces
pombe) 		4 / 5 ILE A 181
PRO A 182
PHE A 263
VAL A 218
 None
None
None
NDP  A 501 ( 4.7A)
 1.16A 2hjhB-2gv8A:
1.3		 2hjhB-2gv8A:
21.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JFA_B_RALB600_2
(ESTROGEN RECEPTOR)		 2gv8 MONOOXYGENASE
(Schizosaccharomy
ces
pombe) 		4 / 4 LEU A  66
THR A  68
ILE A 181
HIS A 200
 None
 1.36A 2jfaB-2gv8A:
undetectable		 2jfaB-2gv8A:
20.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JKJ_A_CLMA1141_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 2gv8 MONOOXYGENASE
(Schizosaccharomy
ces
pombe) 		4 / 6 PRO A  43
GLY A  15
ILE A  11
GLY A  13
 None
FAD  A 500 (-3.4A)
None
FAD  A 500 (-3.1A)
 0.84A 2jkjA-2gv8A:
undetectable		 2jkjA-2gv8A:
14.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JKJ_B_CLMB1141_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 2gv8 MONOOXYGENASE
(Schizosaccharomy
ces
pombe) 		4 / 6 PRO A  43
GLY A  15
ILE A  11
GLY A  13
 None
FAD  A 500 (-3.4A)
None
FAD  A 500 (-3.1A)
 0.84A 2jkjB-2gv8A:
undetectable		 2jkjB-2gv8A:
14.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JKJ_C_CLMC1141_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 2gv8 MONOOXYGENASE
(Schizosaccharomy
ces
pombe) 		4 / 6 PRO A  43
GLY A  15
ILE A  11
GLY A  13
 None
FAD  A 500 (-3.4A)
None
FAD  A 500 (-3.1A)
 0.84A 2jkjC-2gv8A:
undetectable		 2jkjC-2gv8A:
14.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JKJ_E_CLME1141_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 2gv8 MONOOXYGENASE
(Schizosaccharomy
ces
pombe) 		4 / 7 PRO A  43
GLY A  15
ILE A  11
GLY A  13
 None
FAD  A 500 (-3.4A)
None
FAD  A 500 (-3.1A)
 0.83A 2jkjE-2gv8A:
undetectable		 2jkjE-2gv8A:
14.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RHM_B_BEZB194_0
(PUTATIVE KINASE)		 2gv8 MONOOXYGENASE
(Schizosaccharomy
ces
pombe) 		4 / 5 PRO A  70
ARG A  40
ARG A  39
ASP A 137
 None
FAD  A 500 (-4.0A)
FAD  A 500 (-3.6A)
FAD  A 500 (-4.2A)
 1.41A 2rhmB-2gv8A:
1.8		 2rhmB-2gv8A:
18.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RHM_D_BEZD194_0
(PUTATIVE KINASE)		 2gv8 MONOOXYGENASE
(Schizosaccharomy
ces
pombe) 		4 / 5 PRO A  70
ARG A  40
ARG A  39
ASP A 137
 None
FAD  A 500 (-4.0A)
FAD  A 500 (-3.6A)
FAD  A 500 (-4.2A)
 1.43A 2rhmD-2gv8A:
1.8		 2rhmD-2gv8A:
18.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YGQ_A_PCFA1275_0
(WNT INHIBITORY
FACTOR 1)		 2gv8 MONOOXYGENASE
(Schizosaccharomy
ces
pombe) 		5 / 12 LEU A 231
LEU A 278
ILE A 239
PRO A 258
ILE A 260
 None
 0.97A 2ygqA-2gv8A:
undetectable		 2ygqA-2gv8A:
18.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DTU_C_DXCC576_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 2)		 2gv8 MONOOXYGENASE
(Schizosaccharomy
ces
pombe) 		4 / 8 PRO A 344
ALA A 348
ALA A 351
ILE A 399
 None
 0.73A 3dtuC-2gv8A:
undetectable
3dtuD-2gv8A:
undetectable		 3dtuC-2gv8A:
21.93
3dtuD-2gv8A:
17.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KP6_B_SALB3004_1
(TRANSCRIPTIONAL
REGULATOR TCAR)		 2gv8 MONOOXYGENASE
(Schizosaccharomy
ces
pombe) 		4 / 5 ILE A 260
PHE A 263
ASP A 264
GLU A 269
 None
 0.96A 3kp6A-2gv8A:
undetectable
3kp6B-2gv8A:
undetectable		 3kp6A-2gv8A:
17.95
3kp6B-2gv8A:
17.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V1N_A_BEZA288_0
(2-HYDROXY-6-OXO-6-PH
ENYLHEXA-2,4-DIENOAT
E HYDROLASE)		 2gv8 MONOOXYGENASE
(Schizosaccharomy
ces
pombe) 		5 / 8 GLY A  45
GLY A  44
GLY A  18
ILE A 132
LEU A 128
 FAD  A 500 (-3.3A)
None
None
None
None
 1.01A 3v1nA-2gv8A:
undetectable		 3v1nA-2gv8A:
21.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VAS_B_ADNB401_2
(PUTATIVE ADENOSINE
KINASE)		 2gv8 MONOOXYGENASE
(Schizosaccharomy
ces
pombe) 		4 / 5 LEU A  25
ALA A  27
THR A  21
PHE A 417
 None
 1.37A 3vasB-2gv8A:
3.4		 3vasB-2gv8A:
22.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A9J_A_TYLA1188_1
(BROMODOMAIN
CONTAINING 2)		 2gv8 MONOOXYGENASE
(Schizosaccharomy
ces
pombe) 		4 / 5 VAL A 316
LEU A 336
ASN A 173
ILE A 171
 None
 0.94A 4a9jA-2gv8A:
undetectable		 4a9jA-2gv8A:
15.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AFG_C_QMRC1214_1
(CAPITELLA TELETA
ACHBP)		 2gv8 MONOOXYGENASE
(Schizosaccharomy
ces
pombe) 		4 / 8 VAL A 228
TYR A  85
ILE A 239
ILE A 285
 None
 1.02A 4afgD-2gv8A:
undetectable
4afgE-2gv8A:
undetectable		 4afgD-2gv8A:
18.67
4afgE-2gv8A:
18.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E0F_A_RBFA301_2
(RIBOFLAVIN SYNTHASE
SUBUNIT ALPHA)		 2gv8 MONOOXYGENASE
(Schizosaccharomy
ces
pombe) 		3 / 3 LYS A 133
THR A 136
ILE A 161
 None
 0.83A 4e0fB-2gv8A:
undetectable		 4e0fB-2gv8A:
18.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4F84_A_SAMA501_0
(GERANYL DIPHOSPHATE
2-C-METHYLTRANSFERAS
E)		 2gv8 MONOOXYGENASE
(Schizosaccharomy
ces
pombe) 		5 / 12 GLY A  18
GLY A  15
VAL A  20
LEU A 128
VAL A  34
 None
FAD  A 500 (-3.4A)
None
None
None
 1.11A 4f84A-2gv8A:
undetectable		 4f84A-2gv8A:
21.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FGK_A_0TXA302_0
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 2gv8 MONOOXYGENASE
(Schizosaccharomy
ces
pombe) 		4 / 6 PHE A 440
ILE A  94
PRO A  93
PHE A 441
 None
 1.25A 4fgkA-2gv8A:
undetectable		 4fgkA-2gv8A:
20.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FU8_A_ACTA304_0
(UROKINASE-TYPE
PLASMINOGEN
ACTIVATOR)		 2gv8 MONOOXYGENASE
(Schizosaccharomy
ces
pombe) 		3 / 3 ARG A 114
HIS A 113
TYR A  49
 None
None
GOL  A 502 (-4.8A)
 1.18A 4fu8A-2gv8A:
undetectable		 4fu8A-2gv8A:
21.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FU8_A_ACTA304_0
(UROKINASE-TYPE
PLASMINOGEN
ACTIVATOR)		 2gv8 MONOOXYGENASE
(Schizosaccharomy
ces
pombe) 		3 / 3 ARG A 114
HIS A 115
TYR A  49
 None
None
GOL  A 502 (-4.8A)
 1.05A 4fu8A-2gv8A:
undetectable		 4fu8A-2gv8A:
21.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FU9_A_ACTA312_0
(UROKINASE-TYPE
PLASMINOGEN
ACTIVATOR)		 2gv8 MONOOXYGENASE
(Schizosaccharomy
ces
pombe) 		3 / 3 ARG A 114
HIS A 113
TYR A  49
 None
None
GOL  A 502 (-4.8A)
 1.08A 4fu9A-2gv8A:
undetectable		 4fu9A-2gv8A:
21.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FU9_A_ACTA312_0
(UROKINASE-TYPE
PLASMINOGEN
ACTIVATOR)		 2gv8 MONOOXYGENASE
(Schizosaccharomy
ces
pombe) 		3 / 3 ARG A 114
HIS A 115
TYR A  49
 None
None
GOL  A 502 (-4.8A)
 1.07A 4fu9A-2gv8A:
undetectable		 4fu9A-2gv8A:
21.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JEC_B_478B401_3
(HIV-1 PROTEASE)		 2gv8 MONOOXYGENASE
(Schizosaccharomy
ces
pombe) 		3 / 3 ASP A 145
LEU A   3
VAL A 169
 None
 0.48A 4jecB-2gv8A:
undetectable		 4jecB-2gv8A:
12.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L4B_A_CAMA502_0
(CAMPHOR
5-MONOOXYGENASE)		 2gv8 MONOOXYGENASE
(Schizosaccharomy
ces
pombe) 		4 / 8 LEU A 331
VAL A 169
ASP A 140
VAL A 138
 None
None
None
FAD  A 500 (-4.0A)
 1.07A 4l4bA-2gv8A:
undetectable		 4l4bA-2gv8A:
23.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OT2_A_ACTA605_0
(SERUM ALBUMIN)		 2gv8 MONOOXYGENASE
(Schizosaccharomy
ces
pombe) 		3 / 3 LYS A   3
LYS A 143
ALA A 168
 None
 0.96A 4ot2A-2gv8A:
0.0		 4ot2A-2gv8A:
21.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z2D_F_LFXF102_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT B
SYMMETRIZED E-SITE
DNA)		 2gv8 MONOOXYGENASE
(Schizosaccharomy
ces
pombe) 		3 / 4 ARG A  40
GLY A  41
GLU A  38
 FAD  A 500 (-4.0A)
None
FAD  A 500 (-2.5A)
 0.67A 4z2dB-2gv8A:
undetectable
4z2dC-2gv8A:
undetectable		 4z2dB-2gv8A:
22.04
4z2dC-2gv8A:
19.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ERG_B_SAMB401_1
(TRNA
(ADENINE(58)-N(1))-M
ETHYLTRANSFERASE
CATALYTIC SUBUNIT
TRM61)		 2gv8 MONOOXYGENASE
(Schizosaccharomy
ces
pombe) 		4 / 7 GLY A  13
GLY A  15
GLU A  38
ASP A 137
 FAD  A 500 (-3.1A)
FAD  A 500 (-3.4A)
FAD  A 500 (-2.5A)
FAD  A 500 (-4.2A)
 0.65A 5ergB-2gv8A:
3.1		 5ergB-2gv8A:
22.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GSN_C_MMZC503_1
(FLAVIN-CONTAINING
MONOOXYGENASE)		 2gv8 MONOOXYGENASE
(Schizosaccharomy
ces
pombe) 		4 / 4 TYR A  85
ASN A  91
SER A 222
SER A 223
 None
NDP  A 501 ( 3.5A)
NDP  A 501 (-2.9A)
NDP  A 501 (-2.8A)
 0.80A 5gsnC-2gv8A:
35.0		 5gsnC-2gv8A:
25.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L6E_B_ACTB401_0
(N6-ADENOSINE-METHYLT
RANSFERASE 70 KDA
SUBUNIT
N6-ADENOSINE-METHYLT
RANSFERASE SUBUNIT
METTL14)		 2gv8 MONOOXYGENASE
(Schizosaccharomy
ces
pombe) 		4 / 6 GLU A  28
ARG A 360
LEU A 361
ARG A 355
 None
 0.98A 5l6eA-2gv8A:
undetectable
5l6eB-2gv8A:
undetectable		 5l6eA-2gv8A:
18.35
5l6eB-2gv8A:
19.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NUM_A_Z80A201_1
(BETA-LACTOGLOBULIN)		 2gv8 MONOOXYGENASE
(Schizosaccharomy
ces
pombe) 		5 / 8 VAL A 257
ILE A 260
LEU A 272
ILE A 270
ILE A 281
 None
 1.38A 5numA-2gv8A:
undetectable		 5numA-2gv8A:
10.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OEX_A_CUA604_0
(THIOCYANATE
DEHYDROGENASE)		 2gv8 MONOOXYGENASE
(Schizosaccharomy
ces
pombe) 		3 / 3 HIS A 388
HIS A 315
HIS A 317
 None
 0.95A 5oexA-2gv8A:
undetectable		 5oexA-2gv8A:
21.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CP4_A_CAMA422_0
(CYTOCHROME P450CAM)		 2gv8 MONOOXYGENASE
(Schizosaccharomy
ces
pombe) 		4 / 8 LEU A 331
VAL A 169
ASP A 140
VAL A 138
 None
None
None
FAD  A 500 (-4.0A)
 1.08A 6cp4A-2gv8A:
undetectable		 6cp4A-2gv8A:
23.03