SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2gvh'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HK2_A_T44A3003_1
(SERUM ALBUMIN)		 2gvh AGR_L_2016P
(Agrobacterium
fabrum) 		4 / 6 PHE A 200
ILE A 242
ALA A 170
MET A 165
 None
 1.15A 1hk2A-2gvhA:
undetectable		 1hk2A-2gvhA:
18.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RG7_A_MTXA161_2
(DIHYDROFOLATE
REDUCTASE)		 2gvh AGR_L_2016P
(Agrobacterium
fabrum) 		3 / 3 ILE A  20
ILE A  78
THR A  82
 None
 0.63A 1rg7A-2gvhA:
undetectable		 1rg7A-2gvhA:
21.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SJ0_X_DXCX75_0
(CYTOCHROME C7)		 2gvh AGR_L_2016P
(Agrobacterium
fabrum) 		4 / 7 ILE A  22
PHE A  81
MET A  43
GLY A  39
 None
 1.12A 3sj0X-2gvhA:
undetectable		 3sj0X-2gvhA:
13.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SJ0_X_DXCX75_0
(CYTOCHROME C7)		 2gvh AGR_L_2016P
(Agrobacterium
fabrum) 		4 / 7 ILE A  78
PHE A  81
MET A  43
GLY A  39
 None
 1.21A 3sj0X-2gvhA:
undetectable		 3sj0X-2gvhA:
13.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X5F_A_FOLA201_0
(DIHYDROFOLATE
REDUCTASE)		 2gvh AGR_L_2016P
(Agrobacterium
fabrum) 		5 / 12 ILE A  78
ALA A 101
LEU A  34
THR A  82
ARG A  45
 None
 1.12A 4x5fA-2gvhA:
undetectable		 4x5fA-2gvhA:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X5F_B_FOLB201_0
(DIHYDROFOLATE
REDUCTASE)		 2gvh AGR_L_2016P
(Agrobacterium
fabrum) 		5 / 12 ILE A  78
ALA A 101
LEU A  34
THR A  82
ARG A  45
 None
 1.11A 4x5fB-2gvhA:
undetectable		 4x5fB-2gvhA:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DZK_2_BEZ2801_0
(ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 1
BEZ-LEU-LEU)		 2gvh AGR_L_2016P
(Agrobacterium
fabrum) 		4 / 4 LEU A  19
ARG A  53
ILE A  49
ILE A 209
 None
 1.32A 5dzk2-2gvhA:
undetectable
5dzkM-2gvhA:
undetectable
5dzkN-2gvhA:
undetectable		 5dzk2-2gvhA:
1.34
5dzkM-2gvhA:
22.83
5dzkN-2gvhA:
22.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZSF_A_6T0A910_0
(TOLL-LIKE RECEPTOR 7)		 2gvh AGR_L_2016P
(Agrobacterium
fabrum) 		4 / 7 THR A 228
LEU A 230
ILE A 242
THR A 243
 None
 1.03A 5zsfA-2gvhA:
undetectable
5zsfB-2gvhA:
undetectable		 5zsfA-2gvhA:
14.76
5zsfB-2gvhA:
14.76