SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2gwg'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ITU_B_CILB452_1
(RENAL DIPEPTIDASE)		 2gwg 4-OXALOMESACONATE
HYDRATASE
(Rhodopseudomonas
palustris) 		5 / 12 GLU A 284
HIS A   8
HIS A   6
HIS A 223
VAL A 179
 ZN  A 401 (-2.9A)
ZN  A 401 (-3.3A)
ZN  A 401 (-3.4A)
None
None
 1.14A 1ituB-2gwgA:
15.8		 1ituB-2gwgA:
20.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MZ9_A_VDYA1002_2
(CARTILAGE OLIGOMERIC
MATRIX PROTEIN)		 2gwg 4-OXALOMESACONATE
HYDRATASE
(Rhodopseudomonas
palustris) 		3 / 3 ILE A 125
LEU A 128
VAL A 132
 None
 0.44A 1mz9B-2gwgA:
undetectable		 1mz9B-2gwgA:
9.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OS2_D_HAED574_1
(MACROPHAGE
METALLOELASTASE)		 2gwg 4-OXALOMESACONATE
HYDRATASE
(Rhodopseudomonas
palustris) 		4 / 4 HIS A   6
GLU A 284
HIS A   8
HIS A 178
 ZN  A 401 (-3.4A)
ZN  A 401 (-2.9A)
ZN  A 401 (-3.3A)
ZN  A 401 (-3.5A)
 1.06A 1os2D-2gwgA:
undetectable		 1os2D-2gwgA:
18.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTZ_B_HAEB1266_1
(MACROPHAGE
METALLOELASTASE)		 2gwg 4-OXALOMESACONATE
HYDRATASE
(Rhodopseudomonas
palustris) 		4 / 4 HIS A   6
GLU A 284
HIS A   8
HIS A 178
 ZN  A 401 (-3.4A)
ZN  A 401 (-2.9A)
ZN  A 401 (-3.3A)
ZN  A 401 (-3.5A)
 1.08A 1utzB-2gwgA:
undetectable		 1utzB-2gwgA:
17.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V54_N_CUN517_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE I)		 2gwg 4-OXALOMESACONATE
HYDRATASE
(Rhodopseudomonas
palustris) 		3 / 3 HIS A 178
HIS A   8
HIS A   6
 ZN  A 401 (-3.5A)
ZN  A 401 (-3.3A)
ZN  A 401 (-3.4A)
 0.77A 1v54N-2gwgA:
undetectable		 1v54N-2gwgA:
22.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V55_A_CUA517_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE I)		 2gwg 4-OXALOMESACONATE
HYDRATASE
(Rhodopseudomonas
palustris) 		3 / 3 HIS A 178
HIS A   8
HIS A   6
 ZN  A 401 (-3.5A)
ZN  A 401 (-3.3A)
ZN  A 401 (-3.4A)
 0.75A 1v55A-2gwgA:
undetectable		 1v55A-2gwgA:
22.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V55_N_CUN517_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE I)		 2gwg 4-OXALOMESACONATE
HYDRATASE
(Rhodopseudomonas
palustris) 		3 / 3 HIS A 178
HIS A   8
HIS A   6
 ZN  A 401 (-3.5A)
ZN  A 401 (-3.3A)
ZN  A 401 (-3.4A)
 0.75A 1v55N-2gwgA:
undetectable		 1v55N-2gwgA:
22.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WSV_A_THHA3001_1
(AMINOMETHYLTRANSFERA
SE)		 2gwg 4-OXALOMESACONATE
HYDRATASE
(Rhodopseudomonas
palustris) 		3 / 3 ASP A 268
GLU A 317
TYR A 322
 None
 0.78A 1wsvA-2gwgA:
undetectable		 1wsvA-2gwgA:
23.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIK_A_CUA517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 2gwg 4-OXALOMESACONATE
HYDRATASE
(Rhodopseudomonas
palustris) 		3 / 3 HIS A 178
HIS A   8
HIS A   6
 ZN  A 401 (-3.5A)
ZN  A 401 (-3.3A)
ZN  A 401 (-3.4A)
 0.73A 2eikA-2gwgA:
undetectable		 2eikA-2gwgA:
22.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIM_A_CUA517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 2gwg 4-OXALOMESACONATE
HYDRATASE
(Rhodopseudomonas
palustris) 		3 / 3 HIS A 178
HIS A   8
HIS A   6
 ZN  A 401 (-3.5A)
ZN  A 401 (-3.3A)
ZN  A 401 (-3.4A)
 0.74A 2eimA-2gwgA:
undetectable		 2eimA-2gwgA:
22.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HU6_A_HAEA269_1
(MACROPHAGE
METALLOELASTASE)		 2gwg 4-OXALOMESACONATE
HYDRATASE
(Rhodopseudomonas
palustris) 		4 / 4 HIS A   6
GLU A 284
HIS A   8
HIS A 178
 ZN  A 401 (-3.4A)
ZN  A 401 (-2.9A)
ZN  A 401 (-3.3A)
ZN  A 401 (-3.5A)
 1.08A 2hu6A-2gwgA:
undetectable		 2hu6A-2gwgA:
17.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OZR_D_HAED3002_1
(COLLAGENASE 3)		 2gwg 4-OXALOMESACONATE
HYDRATASE
(Rhodopseudomonas
palustris) 		4 / 4 HIS A   6
GLU A 284
HIS A   8
HIS A 178
 ZN  A 401 (-3.4A)
ZN  A 401 (-2.9A)
ZN  A 401 (-3.3A)
ZN  A 401 (-3.5A)
 0.96A 2ozrD-2gwgA:
undetectable		 2ozrD-2gwgA:
15.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PRG_A_BRLA1_2
(PEROXISOME
PROLIFERATOR
ACTIVATED RECEPTOR
GAMMA)		 2gwg 4-OXALOMESACONATE
HYDRATASE
(Rhodopseudomonas
palustris) 		3 / 3 ILE A 177
ILE A 255
LEU A 128
 None
 0.57A 2prgA-2gwgA:
undetectable		 2prgA-2gwgA:
23.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QHF_A_ACTA502_0
(CHORISMATE SYNTHASE)		 2gwg 4-OXALOMESACONATE
HYDRATASE
(Rhodopseudomonas
palustris) 		3 / 3 GLY A  80
ASP A  81
SER A 116
 None
 0.53A 2qhfA-2gwgA:
undetectable		 2qhfA-2gwgA:
20.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y69_A_CUA517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 2gwg 4-OXALOMESACONATE
HYDRATASE
(Rhodopseudomonas
palustris) 		3 / 3 HIS A 178
HIS A   8
HIS A   6
 ZN  A 401 (-3.5A)
ZN  A 401 (-3.3A)
ZN  A 401 (-3.4A)
 0.71A 2y69A-2gwgA:
undetectable		 2y69A-2gwgA:
22.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y69_N_CUN517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 2gwg 4-OXALOMESACONATE
HYDRATASE
(Rhodopseudomonas
palustris) 		3 / 3 HIS A 178
HIS A   8
HIS A   6
 ZN  A 401 (-3.5A)
ZN  A 401 (-3.3A)
ZN  A 401 (-3.4A)
 0.73A 2y69N-2gwgA:
undetectable		 2y69N-2gwgA:
22.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YGO_A_PCFA1213_0
(WNT INHIBITORY
FACTOR 1)		 2gwg 4-OXALOMESACONATE
HYDRATASE
(Rhodopseudomonas
palustris) 		5 / 12 LEU A  65
ILE A   5
ILE A   3
MET A   1
ILE A 173
 None
 1.03A 2ygoA-2gwgA:
undetectable		 2ygoA-2gwgA:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZXW_A_CUA517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 2gwg 4-OXALOMESACONATE
HYDRATASE
(Rhodopseudomonas
palustris) 		3 / 3 HIS A 178
HIS A   8
HIS A   6
 ZN  A 401 (-3.5A)
ZN  A 401 (-3.3A)
ZN  A 401 (-3.4A)
 0.72A 2zxwA-2gwgA:
undetectable		 2zxwA-2gwgA:
22.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZXW_N_CUN517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 2gwg 4-OXALOMESACONATE
HYDRATASE
(Rhodopseudomonas
palustris) 		3 / 3 HIS A 178
HIS A   8
HIS A   6
 ZN  A 401 (-3.5A)
ZN  A 401 (-3.3A)
ZN  A 401 (-3.4A)
 0.75A 2zxwN-2gwgA:
undetectable		 2zxwN-2gwgA:
22.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABK_A_CUA517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 2gwg 4-OXALOMESACONATE
HYDRATASE
(Rhodopseudomonas
palustris) 		3 / 3 HIS A 178
HIS A   8
HIS A   6
 ZN  A 401 (-3.5A)
ZN  A 401 (-3.3A)
ZN  A 401 (-3.4A)
 0.74A 3abkA-2gwgA:
undetectable		 3abkA-2gwgA:
22.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABK_N_CUN517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 2gwg 4-OXALOMESACONATE
HYDRATASE
(Rhodopseudomonas
palustris) 		3 / 3 HIS A 178
HIS A   8
HIS A   6
 ZN  A 401 (-3.5A)
ZN  A 401 (-3.3A)
ZN  A 401 (-3.4A)
 0.71A 3abkN-2gwgA:
undetectable		 3abkN-2gwgA:
22.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABL_A_CUA517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 2gwg 4-OXALOMESACONATE
HYDRATASE
(Rhodopseudomonas
palustris) 		3 / 3 HIS A 178
HIS A   8
HIS A   6
 ZN  A 401 (-3.5A)
ZN  A 401 (-3.3A)
ZN  A 401 (-3.4A)
 0.76A 3ablA-2gwgA:
undetectable		 3ablA-2gwgA:
22.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABL_N_CUN517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 2gwg 4-OXALOMESACONATE
HYDRATASE
(Rhodopseudomonas
palustris) 		3 / 3 HIS A 178
HIS A   8
HIS A   6
 ZN  A 401 (-3.5A)
ZN  A 401 (-3.3A)
ZN  A 401 (-3.4A)
 0.77A 3ablN-2gwgA:
undetectable		 3ablN-2gwgA:
22.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABM_A_CUA517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 2gwg 4-OXALOMESACONATE
HYDRATASE
(Rhodopseudomonas
palustris) 		3 / 3 HIS A 178
HIS A   8
HIS A   6
 ZN  A 401 (-3.5A)
ZN  A 401 (-3.3A)
ZN  A 401 (-3.4A)
 0.73A 3abmA-2gwgA:
undetectable		 3abmA-2gwgA:
22.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABM_N_CUN517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 2gwg 4-OXALOMESACONATE
HYDRATASE
(Rhodopseudomonas
palustris) 		3 / 3 HIS A 178
HIS A   8
HIS A   6
 ZN  A 401 (-3.5A)
ZN  A 401 (-3.3A)
ZN  A 401 (-3.4A)
 0.75A 3abmN-2gwgA:
undetectable		 3abmN-2gwgA:
22.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG1_A_CUA517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 2gwg 4-OXALOMESACONATE
HYDRATASE
(Rhodopseudomonas
palustris) 		3 / 3 HIS A 178
HIS A   8
HIS A   6
 ZN  A 401 (-3.5A)
ZN  A 401 (-3.3A)
ZN  A 401 (-3.4A)
 0.71A 3ag1A-2gwgA:
undetectable		 3ag1A-2gwgA:
22.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG1_N_CUN517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 2gwg 4-OXALOMESACONATE
HYDRATASE
(Rhodopseudomonas
palustris) 		3 / 3 HIS A 178
HIS A   8
HIS A   6
 ZN  A 401 (-3.5A)
ZN  A 401 (-3.3A)
ZN  A 401 (-3.4A)
 0.73A 3ag1N-2gwgA:
undetectable		 3ag1N-2gwgA:
22.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG2_A_CUA517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 2gwg 4-OXALOMESACONATE
HYDRATASE
(Rhodopseudomonas
palustris) 		3 / 3 HIS A 178
HIS A   8
HIS A   6
 ZN  A 401 (-3.5A)
ZN  A 401 (-3.3A)
ZN  A 401 (-3.4A)
 0.74A 3ag2A-2gwgA:
undetectable		 3ag2A-2gwgA:
22.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG2_N_CUN517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 2gwg 4-OXALOMESACONATE
HYDRATASE
(Rhodopseudomonas
palustris) 		3 / 3 HIS A 178
HIS A   8
HIS A   6
 ZN  A 401 (-3.5A)
ZN  A 401 (-3.3A)
ZN  A 401 (-3.4A)
 0.75A 3ag2N-2gwgA:
undetectable		 3ag2N-2gwgA:
22.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG3_A_CUA517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 2gwg 4-OXALOMESACONATE
HYDRATASE
(Rhodopseudomonas
palustris) 		3 / 3 HIS A 178
HIS A   8
HIS A   6
 ZN  A 401 (-3.5A)
ZN  A 401 (-3.3A)
ZN  A 401 (-3.4A)
 0.74A 3ag3A-2gwgA:
undetectable		 3ag3A-2gwgA:
22.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG3_N_CUN517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 2gwg 4-OXALOMESACONATE
HYDRATASE
(Rhodopseudomonas
palustris) 		3 / 3 HIS A 178
HIS A   8
HIS A   6
 ZN  A 401 (-3.5A)
ZN  A 401 (-3.3A)
ZN  A 401 (-3.4A)
 0.74A 3ag3N-2gwgA:
undetectable		 3ag3N-2gwgA:
22.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASN_A_CUA517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 2gwg 4-OXALOMESACONATE
HYDRATASE
(Rhodopseudomonas
palustris) 		3 / 3 HIS A 178
HIS A   8
HIS A   6
 ZN  A 401 (-3.5A)
ZN  A 401 (-3.3A)
ZN  A 401 (-3.4A)
 0.75A 3asnA-2gwgA:
undetectable		 3asnA-2gwgA:
22.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASN_N_CUN517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 2gwg 4-OXALOMESACONATE
HYDRATASE
(Rhodopseudomonas
palustris) 		3 / 3 HIS A 178
HIS A   8
HIS A   6
 ZN  A 401 (-3.5A)
ZN  A 401 (-3.3A)
ZN  A 401 (-3.4A)
 0.73A 3asnN-2gwgA:
undetectable		 3asnN-2gwgA:
22.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASO_A_CUA517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 2gwg 4-OXALOMESACONATE
HYDRATASE
(Rhodopseudomonas
palustris) 		3 / 3 HIS A 178
HIS A   8
HIS A   6
 ZN  A 401 (-3.5A)
ZN  A 401 (-3.3A)
ZN  A 401 (-3.4A)
 0.74A 3asoA-2gwgA:
undetectable		 3asoA-2gwgA:
22.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASO_N_CUN517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 2gwg 4-OXALOMESACONATE
HYDRATASE
(Rhodopseudomonas
palustris) 		3 / 3 HIS A 178
HIS A   8
HIS A   6
 ZN  A 401 (-3.5A)
ZN  A 401 (-3.3A)
ZN  A 401 (-3.4A)
 0.75A 3asoN-2gwgA:
0.7		 3asoN-2gwgA:
22.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DHIC8_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		 2gwg 4-OXALOMESACONATE
HYDRATASE
(Rhodopseudomonas
palustris) 		3 / 3 SER A 100
GLY A 109
GLY A 136
 None
 0.55A 3bogA-2gwgA:
undetectable
3bogC-2gwgA:
undetectable		 3bogA-2gwgA:
undetectable
3bogC-2gwgA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BUF_A_AEGA394_0
(BETA-SECRETASE 1)		 2gwg 4-OXALOMESACONATE
HYDRATASE
(Rhodopseudomonas
palustris) 		4 / 5 LEU A 270
ILE A 321
ILE A 274
GLY A 224
 None
 0.85A 3bufA-2gwgA:
undetectable		 3bufA-2gwgA:
22.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BVD_A_CUA803_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 2gwg 4-OXALOMESACONATE
HYDRATASE
(Rhodopseudomonas
palustris) 		3 / 3 HIS A 178
HIS A   8
HIS A   6
 ZN  A 401 (-3.5A)
ZN  A 401 (-3.3A)
ZN  A 401 (-3.4A)
 0.69A 3bvdA-2gwgA:
undetectable		 3bvdA-2gwgA:
20.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DTU_A_CUA1023_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 2gwg 4-OXALOMESACONATE
HYDRATASE
(Rhodopseudomonas
palustris) 		3 / 3 HIS A 178
HIS A   8
HIS A   6
 ZN  A 401 (-3.5A)
ZN  A 401 (-3.3A)
ZN  A 401 (-3.4A)
 0.71A 3dtuA-2gwgA:
undetectable		 3dtuA-2gwgA:
21.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DTU_C_CUC569_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 2gwg 4-OXALOMESACONATE
HYDRATASE
(Rhodopseudomonas
palustris) 		3 / 3 HIS A 178
HIS A   8
HIS A   6
 ZN  A 401 (-3.5A)
ZN  A 401 (-3.3A)
ZN  A 401 (-3.4A)
 0.74A 3dtuC-2gwgA:
undetectable		 3dtuC-2gwgA:
21.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ELZ_A_CHDA150_0
(ILEAL BILE
ACID-BINDING PROTEIN)		 2gwg 4-OXALOMESACONATE
HYDRATASE
(Rhodopseudomonas
palustris) 		5 / 12 GLN A 264
THR A 303
VAL A 276
ILE A 321
TYR A 322
 None
 1.30A 3elzA-2gwgA:
undetectable		 3elzA-2gwgA:
16.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ELZ_B_CHDB150_0
(ILEAL BILE
ACID-BINDING PROTEIN)		 2gwg 4-OXALOMESACONATE
HYDRATASE
(Rhodopseudomonas
palustris) 		5 / 11 GLN A 264
THR A 303
VAL A 276
ILE A 321
TYR A 322
 None
 1.31A 3elzB-2gwgA:
undetectable		 3elzB-2gwgA:
16.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ELZ_C_CHDC150_0
(ILEAL BILE
ACID-BINDING PROTEIN)		 2gwg 4-OXALOMESACONATE
HYDRATASE
(Rhodopseudomonas
palustris) 		5 / 12 GLN A 264
THR A 303
VAL A 276
ILE A 321
TYR A 322
 None
 1.23A 3elzC-2gwgA:
undetectable		 3elzC-2gwgA:
16.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IXL_A_PACA5000_0
(ARYLMALONATE
DECARBOXYLASE)		 2gwg 4-OXALOMESACONATE
HYDRATASE
(Rhodopseudomonas
palustris) 		5 / 10 THR A 152
SER A 153
VAL A 179
GLY A 149
GLY A 148
 None
 1.25A 3ixlA-2gwgA:
1.7		 3ixlA-2gwgA:
18.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_J_TFPJ202_1
(PROTEIN S100-A4)		 2gwg 4-OXALOMESACONATE
HYDRATASE
(Rhodopseudomonas
palustris) 		5 / 11 ASP A 258
LEU A  65
ASP A   4
LEU A 333
ILE A 108
 None
 1.27A 3ko0A-2gwgA:
undetectable
3ko0B-2gwgA:
undetectable
3ko0I-2gwgA:
undetectable
3ko0J-2gwgA:
0.0		 3ko0A-2gwgA:
14.66
3ko0B-2gwgA:
14.66
3ko0I-2gwgA:
14.66
3ko0J-2gwgA:
14.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KP2_A_PNNA5001_0
(TRANSCRIPTIONAL
REGULATOR TCAR)		 2gwg 4-OXALOMESACONATE
HYDRATASE
(Rhodopseudomonas
palustris) 		4 / 8 THR A  66
SER A 283
HIS A   6
ASN A 141
 None
None
ZN  A 401 (-3.4A)
None
 1.01A 3kp2A-2gwgA:
undetectable
3kp2B-2gwgA:
undetectable		 3kp2A-2gwgA:
18.95
3kp2B-2gwgA:
18.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KPC_A_SAMA1000_0
(UNCHARACTERIZED
PROTEIN MJ0100)		 2gwg 4-OXALOMESACONATE
HYDRATASE
(Rhodopseudomonas
palustris) 		5 / 11 ILE A 274
ILE A 221
ASN A 254
ILE A 255
PRO A 229
 None
 1.19A 3kpcA-2gwgA:
undetectable		 3kpcA-2gwgA:
17.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3POC_B_ACRB665_1
(ALPHA-GLUCOSIDASE)		 2gwg 4-OXALOMESACONATE
HYDRATASE
(Rhodopseudomonas
palustris) 		4 / 6 GLU A  60
ASP A 302
TYR A 299
ASP A 301
 None
 1.34A 3pocB-2gwgA:
4.5		 3pocB-2gwgA:
19.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RFM_A_CFFA330_1
(ADENOSINE RECEPTOR
A2A)		 2gwg 4-OXALOMESACONATE
HYDRATASE
(Rhodopseudomonas
palustris) 		4 / 7 VAL A 138
LEU A  65
MET A   1
ILE A   3
 None
 1.00A 3rfmA-2gwgA:
undetectable		 3rfmA-2gwgA:
23.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S33_A_CUA803_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 2gwg 4-OXALOMESACONATE
HYDRATASE
(Rhodopseudomonas
palustris) 		3 / 3 HIS A 178
HIS A   8
HIS A   6
 ZN  A 401 (-3.5A)
ZN  A 401 (-3.3A)
ZN  A 401 (-3.4A)
 0.77A 3s33A-2gwgA:
undetectable		 3s33A-2gwgA:
20.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S38_A_CUA803_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 2gwg 4-OXALOMESACONATE
HYDRATASE
(Rhodopseudomonas
palustris) 		3 / 3 HIS A 178
HIS A   8
HIS A   6
 ZN  A 401 (-3.5A)
ZN  A 401 (-3.3A)
ZN  A 401 (-3.4A)
 0.77A 3s38A-2gwgA:
undetectable		 3s38A-2gwgA:
20.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S39_A_CUA803_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 2gwg 4-OXALOMESACONATE
HYDRATASE
(Rhodopseudomonas
palustris) 		3 / 3 HIS A 178
HIS A   8
HIS A   6
 ZN  A 401 (-3.5A)
ZN  A 401 (-3.3A)
ZN  A 401 (-3.4A)
 0.79A 3s39A-2gwgA:
undetectable		 3s39A-2gwgA:
20.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S3A_A_CUA803_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 2gwg 4-OXALOMESACONATE
HYDRATASE
(Rhodopseudomonas
palustris) 		3 / 3 HIS A 178
HIS A   8
HIS A   6
 ZN  A 401 (-3.5A)
ZN  A 401 (-3.3A)
ZN  A 401 (-3.4A)
 0.74A 3s3aA-2gwgA:
undetectable		 3s3aA-2gwgA:
20.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S3B_A_CUA803_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 2gwg 4-OXALOMESACONATE
HYDRATASE
(Rhodopseudomonas
palustris) 		3 / 3 HIS A 178
HIS A   8
HIS A   6
 ZN  A 401 (-3.5A)
ZN  A 401 (-3.3A)
ZN  A 401 (-3.4A)
 0.80A 3s3bA-2gwgA:
undetectable		 3s3bA-2gwgA:
20.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S3D_A_CUA803_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 2gwg 4-OXALOMESACONATE
HYDRATASE
(Rhodopseudomonas
palustris) 		3 / 3 HIS A 178
HIS A   8
HIS A   6
 ZN  A 401 (-3.5A)
ZN  A 401 (-3.3A)
ZN  A 401 (-3.4A)
 0.76A 3s3dA-2gwgA:
undetectable		 3s3dA-2gwgA:
20.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U9H_A_NCAA1163_0
(TANKYRASE-2)		 2gwg 4-OXALOMESACONATE
HYDRATASE
(Rhodopseudomonas
palustris) 		4 / 8 GLY A 136
LYS A 130
TYR A 135
GLU A 127
 None
 0.83A 3u9hA-2gwgA:
undetectable		 3u9hA-2gwgA:
20.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U9H_B_NCAB1164_0
(TANKYRASE-2)		 2gwg 4-OXALOMESACONATE
HYDRATASE
(Rhodopseudomonas
palustris) 		4 / 8 GLY A 136
LYS A 130
TYR A 135
GLU A 127
 None
 0.83A 3u9hB-2gwgA:
undetectable		 3u9hB-2gwgA:
20.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WG7_A_CUA603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 2gwg 4-OXALOMESACONATE
HYDRATASE
(Rhodopseudomonas
palustris) 		3 / 3 HIS A 178
HIS A   8
HIS A   6
 ZN  A 401 (-3.5A)
ZN  A 401 (-3.3A)
ZN  A 401 (-3.4A)
 0.71A 3wg7A-2gwgA:
undetectable		 3wg7A-2gwgA:
22.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WG7_N_CUN603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 2gwg 4-OXALOMESACONATE
HYDRATASE
(Rhodopseudomonas
palustris) 		3 / 3 HIS A 178
HIS A   8
HIS A   6
 ZN  A 401 (-3.5A)
ZN  A 401 (-3.3A)
ZN  A 401 (-3.4A)
 0.72A 3wg7N-2gwgA:
undetectable		 3wg7N-2gwgA:
22.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3X2Q_A_CUA604_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 2gwg 4-OXALOMESACONATE
HYDRATASE
(Rhodopseudomonas
palustris) 		3 / 3 HIS A 178
HIS A   8
HIS A   6
 ZN  A 401 (-3.5A)
ZN  A 401 (-3.3A)
ZN  A 401 (-3.4A)
 0.74A 3x2qA-2gwgA:
undetectable		 3x2qA-2gwgA:
22.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3X2Q_N_CUN604_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 2gwg 4-OXALOMESACONATE
HYDRATASE
(Rhodopseudomonas
palustris) 		3 / 3 HIS A 178
HIS A   8
HIS A   6
 ZN  A 401 (-3.5A)
ZN  A 401 (-3.3A)
ZN  A 401 (-3.4A)
 0.71A 3x2qN-2gwgA:
undetectable		 3x2qN-2gwgA:
22.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4BJC_A_RPBA2162_1
(TANKYRASE-2)		 2gwg 4-OXALOMESACONATE
HYDRATASE
(Rhodopseudomonas
palustris) 		4 / 8 GLY A 136
LYS A 130
TYR A 135
GLU A 127
 None
 0.81A 4bjcA-2gwgA:
undetectable		 4bjcA-2gwgA:
20.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EJW_A_SRYA2001_1
(TRANSCRIPTIONAL
REGULATOR TCAR)		 2gwg 4-OXALOMESACONATE
HYDRATASE
(Rhodopseudomonas
palustris) 		5 / 12 LEU A  46
ALA A  48
GLU A  52
GLN A  59
TYR A   9
 None
 1.26A 4ejwA-2gwgA:
0.0		 4ejwA-2gwgA:
18.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EJW_A_SRYA2001_1
(TRANSCRIPTIONAL
REGULATOR TCAR)		 2gwg 4-OXALOMESACONATE
HYDRATASE
(Rhodopseudomonas
palustris) 		5 / 12 LEU A  46
ALA A  48
GLU A  52
SER A  49
TYR A   9
 None
 1.31A 4ejwA-2gwgA:
0.0		 4ejwA-2gwgA:
18.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1A_A_CUA603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 2gwg 4-OXALOMESACONATE
HYDRATASE
(Rhodopseudomonas
palustris) 		3 / 3 HIS A 178
HIS A   8
HIS A   6
 ZN  A 401 (-3.5A)
ZN  A 401 (-3.3A)
ZN  A 401 (-3.4A)
 0.72A 5b1aA-2gwgA:
undetectable		 5b1aA-2gwgA:
22.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1A_N_CUN603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 2gwg 4-OXALOMESACONATE
HYDRATASE
(Rhodopseudomonas
palustris) 		3 / 3 HIS A 178
HIS A   8
HIS A   6
 ZN  A 401 (-3.5A)
ZN  A 401 (-3.3A)
ZN  A 401 (-3.4A)
 0.76A 5b1aN-2gwgA:
undetectable		 5b1aN-2gwgA:
22.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1B_A_CUA603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 2gwg 4-OXALOMESACONATE
HYDRATASE
(Rhodopseudomonas
palustris) 		3 / 3 HIS A 178
HIS A   8
HIS A   6
 ZN  A 401 (-3.5A)
ZN  A 401 (-3.3A)
ZN  A 401 (-3.4A)
 0.72A 5b1bA-2gwgA:
undetectable		 5b1bA-2gwgA:
22.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1B_N_CUN603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 2gwg 4-OXALOMESACONATE
HYDRATASE
(Rhodopseudomonas
palustris) 		3 / 3 HIS A 178
HIS A   8
HIS A   6
 ZN  A 401 (-3.5A)
ZN  A 401 (-3.3A)
ZN  A 401 (-3.4A)
 0.74A 5b1bN-2gwgA:
undetectable		 5b1bN-2gwgA:
22.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B3S_A_CUA603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 2gwg 4-OXALOMESACONATE
HYDRATASE
(Rhodopseudomonas
palustris) 		3 / 3 HIS A 178
HIS A   8
HIS A   6
 ZN  A 401 (-3.5A)
ZN  A 401 (-3.3A)
ZN  A 401 (-3.4A)
 0.73A 5b3sA-2gwgA:
undetectable		 5b3sA-2gwgA:
22.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B3S_N_CUN603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 2gwg 4-OXALOMESACONATE
HYDRATASE
(Rhodopseudomonas
palustris) 		3 / 3 HIS A 178
HIS A   8
HIS A   6
 ZN  A 401 (-3.5A)
ZN  A 401 (-3.3A)
ZN  A 401 (-3.4A)
 0.74A 5b3sN-2gwgA:
undetectable		 5b3sN-2gwgA:
22.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HI2_A_BAXA801_2
(SERINE/THREONINE-PRO
TEIN KINASE B-RAF)		 2gwg 4-OXALOMESACONATE
HYDRATASE
(Rhodopseudomonas
palustris) 		5 / 8 VAL A  67
ILE A 255
ILE A 274
ILE A 221
ASP A 258
 None
 1.21A 5hi2A-2gwgA:
undetectable		 5hi2A-2gwgA:
23.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IY5_A_CUA601_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 2gwg 4-OXALOMESACONATE
HYDRATASE
(Rhodopseudomonas
palustris) 		3 / 3 HIS A 178
HIS A   8
HIS A   6
 ZN  A 401 (-3.5A)
ZN  A 401 (-3.3A)
ZN  A 401 (-3.4A)
 0.73A 5iy5A-2gwgA:
undetectable		 5iy5A-2gwgA:
22.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IY5_N_CUN602_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 2gwg 4-OXALOMESACONATE
HYDRATASE
(Rhodopseudomonas
palustris) 		3 / 3 HIS A 178
HIS A   8
HIS A   6
 ZN  A 401 (-3.5A)
ZN  A 401 (-3.3A)
ZN  A 401 (-3.4A)
 0.74A 5iy5N-2gwgA:
undetectable		 5iy5N-2gwgA:
22.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N5J_A_HAEA306_1
(MACROPHAGE
METALLOELASTASE)		 2gwg 4-OXALOMESACONATE
HYDRATASE
(Rhodopseudomonas
palustris) 		4 / 4 HIS A   6
GLU A 284
HIS A   8
HIS A 178
 ZN  A 401 (-3.4A)
ZN  A 401 (-2.9A)
ZN  A 401 (-3.3A)
ZN  A 401 (-3.5A)
 1.09A 5n5jA-2gwgA:
undetectable		 5n5jA-2gwgA:
17.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5U63_A_ACTA405_0
(THIOREDOXIN
REDUCTASE)		 2gwg 4-OXALOMESACONATE
HYDRATASE
(Rhodopseudomonas
palustris) 		3 / 3 GLY A 226
LEU A 195
HIS A 223
 None
 0.54A 5u63A-2gwgA:
undetectable		 5u63A-2gwgA:
21.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5U63_B_ACTB405_0
(THIOREDOXIN
REDUCTASE)		 2gwg 4-OXALOMESACONATE
HYDRATASE
(Rhodopseudomonas
palustris) 		3 / 3 GLY A 226
LEU A 195
HIS A 223
 None
 0.54A 5u63B-2gwgA:
undetectable		 5u63B-2gwgA:
21.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5W97_A_CUA603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 2gwg 4-OXALOMESACONATE
HYDRATASE
(Rhodopseudomonas
palustris) 		3 / 3 HIS A 178
HIS A   8
HIS A   6
 ZN  A 401 (-3.5A)
ZN  A 401 (-3.3A)
ZN  A 401 (-3.4A)
 0.72A 5w97a-2gwgA:
undetectable		 5w97a-2gwgA:
22.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WAU_A_CUA603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 2gwg 4-OXALOMESACONATE
HYDRATASE
(Rhodopseudomonas
palustris) 		3 / 3 HIS A 178
HIS A   8
HIS A   6
 ZN  A 401 (-3.5A)
ZN  A 401 (-3.3A)
ZN  A 401 (-3.4A)
 0.73A 5waua-2gwgA:
undetectable		 5waua-2gwgA:
22.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X19_A_CUA603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 2gwg 4-OXALOMESACONATE
HYDRATASE
(Rhodopseudomonas
palustris) 		3 / 3 HIS A 178
HIS A   8
HIS A   6
 ZN  A 401 (-3.5A)
ZN  A 401 (-3.3A)
ZN  A 401 (-3.4A)
 0.72A 5x19A-2gwgA:
undetectable		 5x19A-2gwgA:
22.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X19_N_CUN603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 2gwg 4-OXALOMESACONATE
HYDRATASE
(Rhodopseudomonas
palustris) 		3 / 3 HIS A 178
HIS A   8
HIS A   6
 ZN  A 401 (-3.5A)
ZN  A 401 (-3.3A)
ZN  A 401 (-3.4A)
 0.71A 5x19N-2gwgA:
undetectable		 5x19N-2gwgA:
22.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1B_A_CUA603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 2gwg 4-OXALOMESACONATE
HYDRATASE
(Rhodopseudomonas
palustris) 		3 / 3 HIS A 178
HIS A   8
HIS A   6
 ZN  A 401 (-3.5A)
ZN  A 401 (-3.3A)
ZN  A 401 (-3.4A)
 0.65A 5x1bA-2gwgA:
undetectable		 5x1bA-2gwgA:
22.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1B_N_CUN603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 2gwg 4-OXALOMESACONATE
HYDRATASE
(Rhodopseudomonas
palustris) 		3 / 3 HIS A 178
HIS A   8
HIS A   6
 ZN  A 401 (-3.5A)
ZN  A 401 (-3.3A)
ZN  A 401 (-3.4A)
 0.65A 5x1bN-2gwgA:
undetectable		 5x1bN-2gwgA:
22.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1F_A_CUA603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 2gwg 4-OXALOMESACONATE
HYDRATASE
(Rhodopseudomonas
palustris) 		3 / 3 HIS A 178
HIS A   8
HIS A   6
 ZN  A 401 (-3.5A)
ZN  A 401 (-3.3A)
ZN  A 401 (-3.4A)
 0.70A 5x1fA-2gwgA:
undetectable		 5x1fA-2gwgA:
22.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1F_N_CUN603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 2gwg 4-OXALOMESACONATE
HYDRATASE
(Rhodopseudomonas
palustris) 		3 / 3 HIS A 178
HIS A   8
HIS A   6
 ZN  A 401 (-3.5A)
ZN  A 401 (-3.3A)
ZN  A 401 (-3.4A)
 0.67A 5x1fN-2gwgA:
undetectable		 5x1fN-2gwgA:
22.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDQ_A_CUA603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 2gwg 4-OXALOMESACONATE
HYDRATASE
(Rhodopseudomonas
palustris) 		3 / 3 HIS A 178
HIS A   8
HIS A   6
 ZN  A 401 (-3.5A)
ZN  A 401 (-3.3A)
ZN  A 401 (-3.4A)
 0.71A 5xdqA-2gwgA:
undetectable		 5xdqA-2gwgA:
22.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDQ_N_CUN603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 2gwg 4-OXALOMESACONATE
HYDRATASE
(Rhodopseudomonas
palustris) 		3 / 3 HIS A 178
HIS A   8
HIS A   6
 ZN  A 401 (-3.5A)
ZN  A 401 (-3.3A)
ZN  A 401 (-3.4A)
 0.72A 5xdqN-2gwgA:
undetectable		 5xdqN-2gwgA:
22.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDX_A_CUA603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 2gwg 4-OXALOMESACONATE
HYDRATASE
(Rhodopseudomonas
palustris) 		3 / 3 HIS A 178
HIS A   8
HIS A   6
 ZN  A 401 (-3.5A)
ZN  A 401 (-3.3A)
ZN  A 401 (-3.4A)
 0.71A 5xdxA-2gwgA:
undetectable		 5xdxA-2gwgA:
22.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDX_N_CUN603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 2gwg 4-OXALOMESACONATE
HYDRATASE
(Rhodopseudomonas
palustris) 		3 / 3 HIS A 178
HIS A   8
HIS A   6
 ZN  A 401 (-3.5A)
ZN  A 401 (-3.3A)
ZN  A 401 (-3.4A)
 0.71A 5xdxN-2gwgA:
undetectable		 5xdxN-2gwgA:
22.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z84_A_CUA603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 2gwg 4-OXALOMESACONATE
HYDRATASE
(Rhodopseudomonas
palustris) 		3 / 3 HIS A 178
HIS A   8
HIS A   6
 ZN  A 401 (-3.5A)
ZN  A 401 (-3.3A)
ZN  A 401 (-3.4A)
 0.77A 5z84A-2gwgA:
undetectable		 5z84A-2gwgA:
22.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z84_N_CUN604_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 2gwg 4-OXALOMESACONATE
HYDRATASE
(Rhodopseudomonas
palustris) 		3 / 3 HIS A 178
HIS A   8
HIS A   6
 ZN  A 401 (-3.5A)
ZN  A 401 (-3.3A)
ZN  A 401 (-3.4A)
 0.74A 5z84N-2gwgA:
undetectable		 5z84N-2gwgA:
22.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z85_A_CUA603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 2gwg 4-OXALOMESACONATE
HYDRATASE
(Rhodopseudomonas
palustris) 		3 / 3 HIS A 178
HIS A   8
HIS A   6
 ZN  A 401 (-3.5A)
ZN  A 401 (-3.3A)
ZN  A 401 (-3.4A)
 0.77A 5z85A-2gwgA:
0.7		 5z85A-2gwgA:
22.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z85_N_CUN603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 2gwg 4-OXALOMESACONATE
HYDRATASE
(Rhodopseudomonas
palustris) 		3 / 3 HIS A 178
HIS A   8
HIS A   6
 ZN  A 401 (-3.5A)
ZN  A 401 (-3.3A)
ZN  A 401 (-3.4A)
 0.73A 5z85N-2gwgA:
undetectable		 5z85N-2gwgA:
22.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z86_A_CUA603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 2gwg 4-OXALOMESACONATE
HYDRATASE
(Rhodopseudomonas
palustris) 		3 / 3 HIS A 178
HIS A   8
HIS A   6
 ZN  A 401 (-3.5A)
ZN  A 401 (-3.3A)
ZN  A 401 (-3.4A)
 0.72A 5z86A-2gwgA:
undetectable		 5z86A-2gwgA:
22.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z86_N_CUN603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 2gwg 4-OXALOMESACONATE
HYDRATASE
(Rhodopseudomonas
palustris) 		3 / 3 HIS A 178
HIS A   8
HIS A   6
 ZN  A 401 (-3.5A)
ZN  A 401 (-3.3A)
ZN  A 401 (-3.4A)
 0.74A 5z86N-2gwgA:
undetectable		 5z86N-2gwgA:
22.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCO_A_CUA603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 2gwg 4-OXALOMESACONATE
HYDRATASE
(Rhodopseudomonas
palustris) 		3 / 3 HIS A 178
HIS A   8
HIS A   6
 ZN  A 401 (-3.5A)
ZN  A 401 (-3.3A)
ZN  A 401 (-3.4A)
 0.76A 5zcoA-2gwgA:
undetectable		 5zcoA-2gwgA:
22.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCO_N_CUN604_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 2gwg 4-OXALOMESACONATE
HYDRATASE
(Rhodopseudomonas
palustris) 		3 / 3 HIS A 178
HIS A   8
HIS A   6
 ZN  A 401 (-3.5A)
ZN  A 401 (-3.3A)
ZN  A 401 (-3.4A)
 0.73A 5zcoN-2gwgA:
undetectable		 5zcoN-2gwgA:
22.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCP_A_CUA603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 2gwg 4-OXALOMESACONATE
HYDRATASE
(Rhodopseudomonas
palustris) 		3 / 3 HIS A 178
HIS A   8
HIS A   6
 ZN  A 401 (-3.5A)
ZN  A 401 (-3.3A)
ZN  A 401 (-3.4A)
 0.74A 5zcpA-2gwgA:
undetectable		 5zcpA-2gwgA:
22.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCP_N_CUN604_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 2gwg 4-OXALOMESACONATE
HYDRATASE
(Rhodopseudomonas
palustris) 		3 / 3 HIS A 178
HIS A   8
HIS A   6
 ZN  A 401 (-3.5A)
ZN  A 401 (-3.3A)
ZN  A 401 (-3.4A)
 0.77A 5zcpN-2gwgA:
undetectable		 5zcpN-2gwgA:
22.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCQ_A_CUA603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 2gwg 4-OXALOMESACONATE
HYDRATASE
(Rhodopseudomonas
palustris) 		3 / 3 HIS A 178
HIS A   8
HIS A   6
 ZN  A 401 (-3.5A)
ZN  A 401 (-3.3A)
ZN  A 401 (-3.4A)
 0.75A 5zcqA-2gwgA:
undetectable		 5zcqA-2gwgA:
22.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCQ_N_CUN603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 2gwg 4-OXALOMESACONATE
HYDRATASE
(Rhodopseudomonas
palustris) 		3 / 3 HIS A 178
HIS A   8
HIS A   6
 ZN  A 401 (-3.5A)
ZN  A 401 (-3.3A)
ZN  A 401 (-3.4A)
 0.75A 5zcqN-2gwgA:
undetectable		 5zcqN-2gwgA:
22.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HU9_A_CUA601_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 2gwg 4-OXALOMESACONATE
HYDRATASE
(Rhodopseudomonas
palustris) 		3 / 3 HIS A 178
HIS A   8
HIS A   6
 ZN  A 401 (-3.5A)
ZN  A 401 (-3.3A)
ZN  A 401 (-3.4A)
 0.72A 6hu9a-2gwgA:
undetectable		 6hu9a-2gwgA:
22.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HU9_M_CUM601_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 2gwg 4-OXALOMESACONATE
HYDRATASE
(Rhodopseudomonas
palustris) 		3 / 3 HIS A 178
HIS A   8
HIS A   6
 ZN  A 401 (-3.5A)
ZN  A 401 (-3.3A)
ZN  A 401 (-3.4A)
 0.74A 6hu9m-2gwgA:
undetectable		 6hu9m-2gwgA:
22.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NKN_A_CUA601_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 2gwg 4-OXALOMESACONATE
HYDRATASE
(Rhodopseudomonas
palustris) 		3 / 3 HIS A 178
HIS A   8
HIS A   6
 ZN  A 401 (-3.5A)
ZN  A 401 (-3.3A)
ZN  A 401 (-3.4A)
 0.71A 6nknA-2gwgA:
undetectable		 6nknA-2gwgA:
22.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NKN_N_CUN602_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 2gwg 4-OXALOMESACONATE
HYDRATASE
(Rhodopseudomonas
palustris) 		3 / 3 HIS A 178
HIS A   8
HIS A   6
 ZN  A 401 (-3.5A)
ZN  A 401 (-3.3A)
ZN  A 401 (-3.4A)
 0.73A 6nknN-2gwgA:
undetectable		 6nknN-2gwgA:
22.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NMF_A_CUA603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 2gwg 4-OXALOMESACONATE
HYDRATASE
(Rhodopseudomonas
palustris) 		3 / 3 HIS A 178
HIS A   8
HIS A   6
 ZN  A 401 (-3.5A)
ZN  A 401 (-3.3A)
ZN  A 401 (-3.4A)
 0.67A 6nmfA-2gwgA:
undetectable		 6nmfA-2gwgA:
22.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NMF_N_CUN603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 2gwg 4-OXALOMESACONATE
HYDRATASE
(Rhodopseudomonas
palustris) 		3 / 3 HIS A 178
HIS A   8
HIS A   6
 ZN  A 401 (-3.5A)
ZN  A 401 (-3.3A)
ZN  A 401 (-3.4A)
 0.70A 6nmfN-2gwgA:
undetectable		 6nmfN-2gwgA:
22.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NMP_A_CUA601_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 2gwg 4-OXALOMESACONATE
HYDRATASE
(Rhodopseudomonas
palustris) 		3 / 3 HIS A 178
HIS A   8
HIS A   6
 ZN  A 401 (-3.5A)
ZN  A 401 (-3.3A)
ZN  A 401 (-3.4A)
 0.69A 6nmpA-2gwgA:
undetectable		 6nmpA-2gwgA:
22.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NMP_N_CUN601_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 2gwg 4-OXALOMESACONATE
HYDRATASE
(Rhodopseudomonas
palustris) 		3 / 3 HIS A 178
HIS A   8
HIS A   6
 ZN  A 401 (-3.5A)
ZN  A 401 (-3.3A)
ZN  A 401 (-3.4A)
 0.74A 6nmpN-2gwgA:
undetectable		 6nmpN-2gwgA:
22.67